Aliases for WDPCP Gene
External Ids for WDPCP Gene
Previous HGNC Symbols for WDPCP Gene
Previous GeneCards Identifiers for WDPCP Gene
This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for WDPCP Gene
WDPCP (WD Repeat Containing Planar Cell Polarity Effector) is a Protein Coding gene. Diseases associated with WDPCP include congenital heart defects, hamartomas of tongue, and polysyndactyly and bardet-biedl syndrome 15.
UniProtKB/Swiss-Prot for WDPCP Gene
Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements.