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WDPCP Gene

protein-coding   GIFtS: 42
GCID: GC02M063349

WD Repeat Containing Planar Cell Polarity Effector

(Previous name: chromosome 2 open reading frame 86)
(Previous symbol: C2orf86)
  See WDPCP-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
WD Repeat Containing Planar Cell Polarity Effector1 2     FRTZ2
C2orf861 2 3 5     WD Repeat-Containing And Planar Cell Polarity Effector Protein Fritz
Homolog2
BBS152 3 5     WD Repeat-Containing Protein C2orf862
FRITZ2 3     hFRTZ3
Bardet-Biedl Syndrome 15 Protein2 3     WD Repeat-Containing And Planar Cell Polarity Effector Protein3
Chromosome 2 Open Reading Frame 861     

External Ids:    HGNC: 280271   Entrez Gene: 510572   Ensembl: ENSG000001439517   OMIM: 6135805   UniProtKB: O958763   

Export aliases for WDPCP gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for WDPCP Gene:
This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity
protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization.
Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber
syndrome. (provided by RefSeq, Feb 2011)

GeneCards Summary for WDPCP Gene:
WDPCP (WD repeat containing planar cell polarity effector) is a protein-coding gene. Diseases associated with WDPCP include wdpcp-related bardet-biedl syndrome, and bardet-biedl syndrome.

UniProtKB/Swiss-Prot: FRITZ_HUMAN, O95876
Function: Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton
in both ciliogenesis and collective cell movements (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for WDPCP
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for WDPCP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDPCP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p15   Ensembl cytogenetic band:  2p15   HGNC cytogenetic band: 2p15

WDPCP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDPCP gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M063349:  view genomic region     (about GC identifiers)

Start:
63,348,518 bp from pter      End:
64,054,977 bp from pter
Size:
706,460 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FRITZ_HUMAN, O95876 (See protein sequence)
Recommended Name: WD repeat-containing and planar cell polarity effector protein fritz homolog  
Size: 746 amino acids; 85084 Da
Caution: It is uncertain whether Met-1 or Met-34 is the initiator
Secondary accessions: Q53RW4 Q7Z2Z3
Alternative splicing: 3 isoforms:  O95876-1   O95876-2   O95876-3   

Explore the universe of human proteins at neXtProt for WDPCP: NX_O95876

Explore proteomics data for WDPCP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See WDPCP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056994.3  
    ENSEMBL proteins: 
     ENSP00000386795   ENSP00000272321   ENSP00000386592   ENSP00000386769   ENSP00000381552  
     ENSP00000387222   ENSP00000411429   ENSP00000430288   ENSP00000409982   ENSP00000396226  

    WDPCP Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for WDPCP
    OriGene Custom MassSpec
    OriGene Custom Protein Services for WDPCP
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    Novus Biologicals WDPCP Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for WDPCP 

    WDPCP Antibody Products:

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    Search for Antibodies for WDPCP at Abcam
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    ThermoFisher Antibodies for WDPCP
    LSBio Antibodies in human, mouse, rat for WDPCP

    WDPCP Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for WDPCP 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR024511 frtz
     IPR017986 WD40_repeat_dom

    Graphical View of Domain Structure for InterPro Entry O95876

    ProtoNet protein and cluster: O95876

    UniProtKB/Swiss-Prot: FRITZ_HUMAN, O95876
    Similarity: Belongs to the WD repeat fritz family
    Similarity: Contains 2 WD repeats


    Find genes that share domains with WDPCP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FRITZ_HUMAN, O95876
    Function: Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton
    in both ciliogenesis and collective cell movements (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with WDPCP           About GenesLikeMe


    Phenotypes:
         13 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Wdpcp):
     cardiovascular system  cellular  craniofacial  digestive/alimentary  embryogenesis 
     hearing/vestibular/ear  limbs/digits/tail  mortality/aging  nervous system  no phenotypic analysis 
     renal/urinary system  respiratory system  vision/eye 

    Find genes that share phenotypes with WDPCP           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Wdpcptm1.1Clo for WDPCP

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WDPCP
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for WDPCP

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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDPCP

    miRNA
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    Block miRNA regulation of human, mouse, rat WDPCP using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate WDPCP:
    hsa-miR-323-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat WDPCP

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: WDPCP (NM_015910)
    Sino Biological Human cDNA Clone for WDPCP
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDPCP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDPCP

    Cell Line
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FRITZ_HUMAN, O95876: Cell membrane (By similarity). Cytoplasm, cytoskeleton, cilium axoneme (By similarity)

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton IEA--
    GO:0005886colocalizes with plasma membrane ISS--
    GO:0005930axoneme ISS--
    GO:0005938colocalizes with cell cortex ISS--
    GO:0016324colocalizes with apical plasma membrane ISS--

    Find genes that share ontologies with WDPCP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDPCP
    Interactions:

        Search GeneGlobe Interaction Network for WDPCP

    1 Interacting protein for WDPCP (O958763) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RCHY1Q96PM53I2D: score=5 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016476regulation of embryonic cell shape ISS--
    GO:0032185septin cytoskeleton organization ISS--
    GO:0032880regulation of protein localization ISS--
    GO:0060271cilium morphogenesis ISS--

    Find genes that share ontologies with WDPCP           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDPCP (FRITZ)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for WDPCP gene (2 alternative transcripts): 
    NM_015910.5  NM_001042692.1  

    Unigene Cluster for WDPCP:

    WD repeat containing planar cell polarity effector
    Hs.414952  [show with all ESTs]
    Unigene Representative Sequence: BX647132
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409354 ENST00000272321(uc002sce.3 uc002scf.3 uc010ypu.2 uc002sch.3)
    ENST00000409199 ENST00000487280 ENST00000409120(uc002scg.3) ENST00000398544
    ENST00000409562 ENST00000409835 ENST00000417238(uc002sci.2) ENST00000462652
    ENST00000493315(uc010fcr.1) ENST00000473678 ENST00000418148 ENST00000490935
    ENST00000431065 ENST00000467687 ENST00000484073
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat WDPCP using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate WDPCP:
    hsa-miR-323-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for WDPCP
    Predesigned siRNA for gene silencing in human, mouse, rat WDPCP
    Clone
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    OriGene ORF clones in mouse, rat for WDPCP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDPCP (NM_015910)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDPCP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDPCP
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for WDPCP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDPCP
      QuantiTect SYBR Green Assays in human, mouse, rat WDPCP
      QuantiFast Probe-based Assays in human, mouse, rat WDPCP

    Additional mRNA sequence: 

    AF131737.1 AK001849.1 AK022647.1 AK055030.1 AK309028.1 AK310290.1 AL833623.1 BC093752.1 
    BC093754.1 BC143426.1 BX538331.1 BX647132.1 

    13 DOTS entries:

    DT.308953  DT.91720641  DT.95248434  DT.95366272  DT.40222722  DT.97838476  DT.100754390  DT.101981220 
    DT.91941635  DT.95366275  DT.100731062  DT.121010411  DT.121010510 

    Selected AceView cDNA sequences (see all 61):

    BE888656 AI279372 AL833623 AF131737 NM_015910 CB153284 AK022647 BG198790 
    BG575480 AW195576 AA568660 BG479284 AA911152 BG184304 AK055030 AI265876 
    AW078538 BE883073 BF111261 AK001849 BX478657 BE541068 AU135376 AI458350 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WDPCP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTGTGAAGC
    WDPCP Expression
    About this image


    WDPCP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Late Floor Plate Cells Mesencephalic Floor Plate
             Diencephalic Roof Plate
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Midbrain tegmentum
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Testis (Reproductive System)
    WDPCP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDPCP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.414952
        Custom PCR Arrays for WDPCP
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDPCP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for WDPCP gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdpcp1 , 5 WD repeat containing planar cell polarity effector1, 5 83.52(n)1
    79.78(a)1
      11 (13.90 cM)5
    2165601  NM_145425.31  NP_663400.21 
     215722355 
    chicken
    (Gallus gallus)
    Aves WDPCP1 WD repeat containing planar cell polarity effector 75.6(n)
    72.57(a)
      428553  XM_426108.4  XP_426108.4 
    lizard
    (Anolis carolinensis)
    Reptilia WDPCP6
    WD repeat containing planar cell polarity effector...
    62(a)
    1 ↔ 1
    1(120671917-120859317)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.142302 Transcribed sequence with weak similarity to protein more 76.86(n)    137716954 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003331251 WD repeat-containing and planar cell polarity effector more 54.56(n)
    46.45(a)
      100333125  XM_005158535.1  XP_005158592.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta frtz1 fritz 42.11(n)
    31.11(a)
      33349  NM_001272950.1  NP_001259879.1 


    ENSEMBL Gene Tree for WDPCP (if available)
    TreeFam Gene Tree for WDPCP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for WDPCP gene
    1 SIMAP similar gene for WDPCP using alignment to 6 protein entries:     FRITZ_HUMAN (see all proteins):
    LOC51057

    Find genes that share paralogs with WDPCP           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WDPCP (see all 7722)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1435964461,2
    C--63105229(+) TGTAT-/ACACACA 1 -- int10--------
    rs1434193261,2
    C--63108875(+) TAGGG-/GTGT  
            
    GTGTG
    1 -- int10--------
    rs2007835091,2
    C--63108875(+) TAGGG-/GTGTGTG 1 -- int10--------
    rs790655831,2
    C--63112931(+) ATGGGG/TTTTTC 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1903777541,2
    --63115693(+) ACACAC/TACACA 1 -- int10--------
    rs340013221,2
    C--63125805(+) AAAAA-/AGCAAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs799830191,2
    C--63171963(-) TCCACG/ACACCT 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1155701201,2
    C,F--63214049(+) GAAGGG/TTATGA 1 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1414396051,2
    --63214095(+) ACTATA/GGTTTC 1 -- ds50010--------
    rs1168827881,2
    F--63214234(+) TAGATG/TACACC 1 -- ds50011Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for WDPCP (63348518 - 63598518 bp, first 250kb of WDPCP)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for WDPCP (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2673093CNV Deletion23128226
    esv2035676CNV Deletion18987734
    esv2659646CNV Deletion23128226
    dgv705e199CNV Deletion23128226
    nsv2752CNV Insertion18451855
    esv1628034CNV Insertion17803354
    esv2479838CNV Insertion19546169
    esv1071119CNV Insertion17803354
    nsv874234CNV Loss21882294
    nsv470468CNV Loss18288195

    Human Gene Mutation Database (HGMD): WDPCP
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing WDPCP
    DNA2.0 Custom Variant and Variant Library Synthesis for WDPCP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613580   
    OMIM disorders: 209900  
    UniProtKB/Swiss-Prot: FRITZ_HUMAN, O95876
  • Bardet-Biedl syndrome 15 (BBS15) [MIM:209900]: A syndrome characterized by usually severe pigmentary
    retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation.
    Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome
    inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus)
    may be required for clinical manifestation of some forms of the disease. Note=The disease is caused by mutations
    affecting the gene represented in this entry
  • Note=Mutations in WDPCP may act as modifiers of the phenotypic expression of Bardet-Biedl syndrome and
    Meckel syndrome by interacting in trans with primary BBS and MKS loci

  • 5 diseases for WDPCP:    
    About MalaCards
    wdpcp-related bardet-biedl syndrome    bardet-biedl syndrome    meckel syndrome 1    bardet-biedl syndrome, modifier of
    bardet-biedl syndrome 15


    Find genes that share disorders with WDPCP           About GenesLikeMe


    Export disorders for WDPCP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WDPCP gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with WDPCP)
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    1. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. (PubMed id 20671153)1, 2 Kim S.K....Wallingford J.B. (Science 2010)
    2. The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis. (PubMed id 15654087)1, 3 Collier S....Adler P. (Genetics 2005)
    3. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    6. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PubMed id 18464913)1 Melzer D....Ferrucci L. (PLoS Genet. 2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51057 HGNC: 28027 AceView: LOC51057 Ensembl:ENSG00000143951 euGenes: HUgn51057
    ECgene: WDPCP H-InvDB: WDPCP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for WDPCP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for WDPCP gene:
    Search GeneIP for patents involving WDPCP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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