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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

WDFY4 Gene

protein-coding GIFtS: 44
GCID: GC10P049892

WDFY family member 4

(Previous name: chromosome 10 open reading frame 64 )
(Previous symbol: C10orf64)

Explore 6 diseases affiliated with
WDFY4 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
WDFY Family Member 4¹ ²		Chromosome 10 Open Reading Frame 64¹
C10orf64¹ ² ³		WD Repeat- And FYVE Domain-Containing Protein 4²
KIAA1607¹ ³ ⁵		EC 3.5.1.18⁸
Em:AC060234.3¹		EC 3.6.3.12⁸
FLJ45748¹

External Ids:	HGNC: 29323¹	Entrez Gene: 57705²	Ensembl: ENSG00000128815⁷	OMIM: 613316⁵	UniProtKB: Q6ZS81³

Export aliases for WDFY4 gene to outside databases

Previous GC identifers: GC10P049313 GC10U900444 GC10P049563 GC10P044158

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the WDFY4 gene promoter:
AML1a FOXD3 STAT3 Pax-4a FOXL1 C/EBPalpha
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for WDFY4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDFY4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.23 Ensembl cytogenetic band: 10q11.22 HGNC cytogenetic band: 10q11.23

WDFY4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDFY4 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P049892: view genomic region (about GC identifiers)

Start:	49,892,921 bp from pter	End:	50,191,001 bp from pter
Size:	298,081 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: WDFY4_HUMAN, Q6ZS81 (See protein sequence)

Recommended Name: WD repeat- and FYVE domain-containing protein 4

Size: 3184 amino acids; 353610 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Secondary accessions: B9ZVP2 Q86WZ4 Q8N4A3 Q8TEN7 Q96BE1 Q9H7H8 Q9HCG5

Alternative splicing: 5 isoforms: Q6ZS81-1 Q6ZS81-2 Q6ZS81-3 Q6ZS81-4 Q6ZS81-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for WDFY4: NX_Q6ZS81

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZS81

3 DME Specific Peptides for WDFY4 (Q6ZS81)

GQVIGSA

LTFFPAL

STVEGLQ

WDFY4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065996.1

ENSEMBL proteins:

ENSP00000354141 ENSP00000407881 ENSP00000309314 ENSP00000363276 ENSP00000265453

ENSP00000320563 ENSP00000403789

Human Recombinant Protein Products:

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	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for WDFY4
	GenScript Custom Purified and Recombinant Proteins Services for WDFY4
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for WDFY4

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

WDFY4 for ontologies About GeneDecksing

WDFY4 Antibody Products:

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	Novus Biologicals WDFY4 Antibody
	Search for Antibodies for WDFY4 at Abcam
	Uscn Antibodies for WDFY4
	Search ThermoFisher Antibodies for WDFY4

Assay Products for WDFY4:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for WDFY4
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for WDFY4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

WDFY4 for domains About GeneDecksing

5/8 InterPro domains/families (see all 8):

IPR000409 BEACH_dom

IPR011989 ARM-like

IPR019775 WD40_repeat_CS

IPR001680 WD40_repeat

IPR017986 WD40_repeat_dom

Graphical View of Domain Structure for InterPro Entry Q6ZS81

ProtoNet protein and cluster: Q6ZS81

UniProtKB/Swiss-Prot: WDFY4_HUMAN, Q6ZS81

Similarity: Contains 1 BEACH domain

Similarity: Contains 5 WD repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Enzyme Numbers (IUBMB): EC 3.6.3.12² EC 3.5.1.18²

miRNA Products:		OriGene 3'-UTR Clone: WDFY4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDFY4
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDFY4:
		hsa-miR-3163 hsa-miR-152 hsa-miR-148b hsa-miR-548u hsa-miR-148a
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDFY4 OriGene shRNA RFP: WDFY4 OriGene siRNA: WDFY4
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for WDFY4

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDFY4 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDFY4 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: WDFY4 (NM_020945)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for WDFY4
		Search LifeMap BioReagents cell lines for WDFY4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDFY4

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for WDFY4

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for WDFY4
Search CenterWatch for drugs/clinical trials and news about WDFY4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for WDFY4 gene:

NM_020945.1

Unigene Cluster for WDFY4:

WDFY family member 4

Hs.287379 [show with all ESTs]

Unigene Representative Sequence: NM_020945

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000360890(uc001jgy.3) ENST00000454161 ENST00000312002 ENST00000374161(uc001jhb.1)

ENST00000265453(uc009xob.3 uc010qgn.1) ENST00000465910 ENST00000497480

ENST00000490507 ENST00000325239(uc001jha.4) ENST00000413659

miRNA Products:		OriGene 3'-UTR Clone: WDFY4 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDFY4
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDFY4:
		hsa-miR-3163 hsa-miR-152 hsa-miR-148b hsa-miR-548u hsa-miR-148a
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDFY4 OriGene shRNA RFP: WDFY4 OriGene siRNA: WDFY4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDFY4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDFY4 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDFY4 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: WDFY4 (NM_020945)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDFY4
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat WDFY4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDFY4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat WDFY4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDFY4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDFY4

Additional cDNA sequence:

AB046827.1 AK074085.1 AK074443.1 AK093607.1 AK127650.1 AK301736.1 AL833669.1 BC015694.2

BC032420.1 BC034937.1 BC047574.1

11 DOTS entries:

DT.207837 DT.86853800 DT.100746825 DT.99928057 DT.91862719 DT.101958248 DT.97803385 DT.100865949

DT.121230791 DT.97814933 DT.40311322

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for WDFY4 (see all 12) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15a	·	15b	^	16	^	17a	·	17b	^	18	^	19	^	20	^	21a	·	21b	·	21c	^
SP1:
SP2:
SP3:																									-
SP4:
SP5:			-

ExUns:	22a	·	22b	^	23	^	24	^	25	^	26	^	27	^	28	^	29	^	30	^	31	^	32	^	33	^	34	^	35	^	36a	·	36b	^	37	^	38	^	39	^	40	^	41	^	42	^	43	^	44	^	45	^
SP1:											-																										-										-
SP2:																																					-										-
SP3:
SP4:
SP5:

ExUns:	46a	·	46b	^	47	^	48	^	49a	·	49b	^	50	^	51	^	52	^	53	^	54a	·	54b	^	55	^	56	^	57	^	58	^	59	^	60a	·	60b	^	61	^	62	^	63	^	64a	·	64b	^	65	^	66a	·
SP1:									-																										-
SP2:									-																										-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for WDFY4

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

WDFY4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

WDFY4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Blimp1- mVenus and stella-ECFP genetically modified stem cells (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See WDFY4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDFY4

SOURCE GeneReport for Unigene cluster: Hs.287379

SABiosciences Custom PCR Arrays for WDFY4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDFY4 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDFY4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDFY4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDFY4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDFY4 gene from 6/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Wdfy4^{1 , 5}	WD repeat and FYVE domain containing 4^{1, 5}	82.72(n)¹ 82.53(a)¹		14 (19.44 cM)⁵ 545030¹ NM_001146022.1¹ NP_001139494.1¹ 32959570⁵
chicken (Gallus gallus)	Aves	WDFY4¹	WDFY family member 4	64.22(n) 59.65(a)		423781 XM_003641478.1 XP_003641526.1
African clawed frog (Xenopus laevis)	Amphibia	CD326631.1²	--	73.82(n)		CD326631.1
zebrafish (Danio rerio)	Actinopterygii	wdfy4¹	WDFY family member 4	53.43(n) 43.41(a)		572477 XM_696196.5 XP_701288.5
thale cress (Arabidopsis thaliana)	eudicotyledons	SPI⁶ AT4G02660⁶	Beige/BEACH and WD40 domain-containing protein	16(a) 16(a)	many ↔ many many ↔ many	1(712473-726891) 4(1159667-1174321)
rice (Oryza sativa)	Liliopsida	--	WD domain containing protein, putative, expressed	16(a)	1 → many	3(30557073-30574933)

ENSEMBL Gene Tree for WDFY4 (if available)
TreeFam Gene Tree for WDFY4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for WDFY4 gene

NSMAF² LYST² LRBA² NBEAL1² NBEA² WDFY3² NBEAL2²

3 SIMAP similar genes for WDFY4 using alignment to 7 protein entries: WDFY4_HUMAN (see all proteins):

WDFY3 NBEA DKFZp686K03100

WDFY4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs111318849^1,2		--	44282775(+)	`ACCATC/AATTAT`	1	--	int¹		2		CSA WA	120
rs199845032^1,2	C	--	44382247(+)	`TTTTTA/TANNNN`	1	--	int¹		0	--	--	--	--
rs190605491^1,2		--	49891593(+)	`GGTGGA/GCCCTC`	1	--	us2k¹		0	--	--	--	--
rs111536127^1,2	C,	--	49891719(+)	`CCTCTG/-GTCTA`	1	--	us2k¹		1		CSA	2
rs11373535^1,2	C	--	49891720(+)	`CTCTG-/GTCTAA`	1	--	us2k¹		0	--	--	--	--
rs77575816^1,2	C,	--	49891728(+)	`TAATCC/AGCTCT`	1	--	us2k¹		4		NA WA	242
rs143264587^1,2		--	49891731(+)	`TCCGCC/TCTTAC`	1	--	us2k¹		0	--	--	--	--
rs150585375^1,2		--	49892120(+)	`GCCTC-/TCA GTCAGTCATG`	1	--	us2k¹		0	--	--	--	--
rs182326103^1,2		--	49892138(+)	`CATGGG/TCCACT`	1	--	us2k¹		0	--	--	--	--
rs72787278^1,2	C,F,	--	49892166(+)	`ACAAGC/AGATGA`	1	--	us2k¹		2		NA EA	240

HapMap Linkage Disequilibrium report for WDFY4 (49892921 - 50142921 bp, first 250kb of WDFY4)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for WDFY4
4 CNVs: 48562 6869 100941 48561
7 Indels: 42369 61019 60012 48560 44755 39748 24505
Human Gene Mutation Database (HGMD): WDFY4

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDFY4

DNA2.0 Custom Variant and Variant Library Synthesis for WDFY4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

WDFY4 for disorders           About GeneDecksing

OMIM gene information: 613316    OMIM disorders: --

6 diseases for WDFY4:    About MalaCards

chediak-higashi syndrome systemic lupus erythematosus lupus erythematosus alzheimer's disease

atherosclerosis malaria

Human Genome Epidemiology (HuGE) Navigator: WDFY4 (5 documents)

Export disorders for WDFY4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for WDFY4 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with WDFY4)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)^{1, 2, 3} Nagase T.... Ohara O. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Pharmacogenomic study of side-effects for antidepressa nt treatment options in STAR*D. (PubMed id 22041458)¹ Clark S.L....van den Oord E.J. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Genome-wide association study in Asian populations id entifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosu s. (PubMed id 20169177)¹ Yang W....Lau Y.L. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Genome-wide association study in a Chinese Han popula tion identifies nine new susceptibility loci for systemic lupus erythematosus. (PubMed id 19838193)¹ Han J.W....Zhang X.J. (2009)
Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)¹ Uhl G.R....Lerman C. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57705	HGNC: 29323	Ensembl:ENSG00000128815	euGenes: HUgn57705	ECgene: WDFY4
H-InvDB: WDFY4

(According to HUGE)
About This Section

HUGE: KIAA1607

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for WDFY4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for WDFY4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for WDFY4 gene:
Search GeneIP for patents involving WDFY4

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WDFY4 Gene

WDFY family member 4

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WDFY4 Gene

WDFY family member 4

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