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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDFY3 Gene

protein-coding   GIFtS: 54
GCID: GC04M085590

WD Repeat And FYVE Domain Containing 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WD Repeat And FYVE Domain Containing 31 2     WD Repeat And FYVE Domain-Containing Protein 32
Autophagy-Linked FYVE Protein2 3     Alfy3
ALFY2     KIAA09933
ZFYVE252     

External Ids:    HGNC: 207511   Entrez Gene: 230012   Ensembl: ENSG000001636257   UniProtKB: Q8IZQ13   

Export aliases for WDFY3 gene to outside databases

Previous GC identifers: GC04M085884 GC04M086049 GC04M085947 GC04M085809 GC04M081332


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDFY3 Gene:
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for
aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated
proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of
these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. (provided by
RefSeq, May 2010)

GeneCards Summary for WDFY3 Gene: 
WDFY3 (WD repeat and FYVE domain containing 3) is a protein-coding gene. Diseases associated with WDFY3 include chediak-higashi syndrome, and paget's disease of bone. GO annotations related to this gene include 1-phosphatidylinositol binding and beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity. An important paralog of this gene is NSMAF.

Gene Wiki entry for WDFY3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDFY3 gene promoter:
         AML1a   GCNF   Pax-6   Lmo2   PPAR-alpha   Nkx6-1   HFH-1   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDFY3 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDFY3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDFY3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.23   Ensembl cytogenetic band:  4q21.23   HGNC cytogenetic band: 4q21.3

WDFY3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDFY3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M085590:  view genomic region     (about GC identifiers)

Start:
85,590,690 bp from pter      End:
85,887,544 bp from pter
Size:
296,855 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDFY3_HUMAN, Q8IZQ1 (See protein sequence)
Recommended Name: WD repeat and FYVE domain-containing protein 3  
Size: 3526 amino acids; 395258 Da
Subcellular location: Membrane; Peripheral membrane protein; Cytoplasmic side. Note=Co-localizes with autophagic
structures in starved cells
Sequence caution: Sequence=AAH13377.1; Type=Erroneous initiation; Sequence=AAH15214.2; Type=Erroneous initiation;
Sequence=BAB71020.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=BAC04455.1; Type=Erroneous
initiation;
Secondary accessions: Q4W5K5 Q6P0Q5 Q8N1T2 Q8NAV6 Q96BS7 Q96D33 Q96N85 Q9Y2J7
Alternative splicing: 2 isoforms:  Q8IZQ1-1   Q8IZQ1-2   

Explore the universe of human proteins at neXtProt for WDFY3: NX_Q8IZQ1

Explore proteomics data for WDFY3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IZQ1

  • WDFY3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDFY3 Protein Expression
    REFSEQ proteins: NP_055806.2  
    ENSEMBL proteins: 
     ENSP00000295888   ENSP00000424987   ENSP00000426813   ENSP00000425699   ENSP00000422741  
     ENSP00000318466  

    Human Recombinant Protein Products for WDFY3: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WDFY3 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IDA15292400
    GO:0005737cytoplasm IDA15292400
    GO:0005776colocalizes with autophagic vacuole IDA15292400
    GO:0019898extrinsic to membrane IDA15292400

    WDFY3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZFYVE: Zinc fingers, FYVE domain containing
    WDR: WD repeat domain containing

    5/13 InterPro protein domains (see all 13):
     IPR000409 BEACH_dom
     IPR011989 ARM-like
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR000306 Znf_FYVE

    Graphical View of Domain Structure for InterPro Entry Q8IZQ1

    ProtoNet protein and cluster: Q8IZQ1

    2 Blocks protein domains:
    IPB000306 Zn-finger
    IPB000409 Beige/BEACH domain


    UniProtKB/Swiss-Prot: WDFY3_HUMAN, Q8IZQ1
    Similarity: Contains 1 BEACH domain
    Similarity: Contains 1 FYVE-type zinc finger
    Similarity: Contains 5 WD repeats


    WDFY3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003831beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA--
    GO:0005488binding ----
    GO:0005515protein binding IPI--
    GO:00055451-phosphatidylinositol binding IDA15292400
    GO:0046872metal ion binding IEA--
         
    WDFY3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for WDFY3:
     Decreased BPV1 E2 protein expr  Increased G1 DNA content  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDFY3 
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    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): WDFY3 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDFY3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDFY3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/19 Interacting proteins for WDFY3 (Q8IZQ11, 3 ENSP000002958884) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HTTP428581, 3, ENSP000003471844EBI-1569256,EBI-466029 I2D: score=2 STRING: ENSP00000347184
    ENSG00000206495Q9HCM93I2D: score=1 
    ENSG00000224994Q9HCM93I2D: score=1 
    ENSG00000226437Q9HCM93I2D: score=1 
    ENSG00000229929Q9HCM93I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDFY3

    Search CenterWatch for drugs/clinical trials and news about WDFY3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDFY3 gene (3 alternative transcripts): 
    NM_014991.4  NM_178583.2  NM_178585.2  

    Unigene Cluster for WDFY3:

    WD repeat and FYVE domain containing 3
    Hs.480116  [show with all ESTs]
    Unigene Representative Sequence: NM_014991
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000295888 ENST00000425179 ENST00000514711 ENST00000504839 ENST00000509825
    ENST00000505923 ENST00000512267 ENST00000426414(uc003hpf.3) ENST00000514071
    ENST00000504990 ENST00000509172 ENST00000502713 ENST00000322366(uc003hpc.3 uc003hpd.3 uc003hpe.1)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDFY3
    8/73 QIAGEN miScript miRNA Assays for microRNAs that regulate WDFY3 (see all 73):
    hsa-miR-140-5p hsa-miR-188-5p hsa-miR-106a hsa-miR-200a hsa-miR-519a hsa-miR-3916 hsa-miR-93 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): WDFY3 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDFY3
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    Additional mRNA sequence: 

    AB023210.2 AF131845.1 AK055806.1 AK092394.1 AK094910.1 BC015214.1 BC065502.1 BC150246.1 
    BX648077.1 BX648153.1 EF491804.1 EF491819.1 

    13 DOTS entries:

    DT.455599  DT.100779276  DT.95169174  DT.97808164  DT.121227189  DT.95256526  DT.100746625  DT.100779275 
    DT.40283706  DT.92005579  DT.95215555  DT.40265912  DT.91705863 

    24/206 AceView cDNA sequences (see all 206):

    BM661628 BQ008027 AI796438 AA973044 BQ960724 AB023210 BC065502 BE348236 
    AA321218 AK094910 CA314071 NM_178585 BM259606 AL536320 BM987247 BF514129 
    AI521819 AI423502 BE221984 AW614988 AW338128 AI341993 AI393528 BQ129293 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDFY3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTAAATGCA
    WDFY3 Expression
    About this image


    See WDFY3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDFY3

    SOURCE GeneReport for Unigene cluster: Hs.480116

    UniProtKB/Swiss-Prot: WDFY3_HUMAN, Q8IZQ1
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for WDFY3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDFY3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDFY3 gene from 9/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdfy31 , 5 WD repeat and FYVE domain containing 31, 5 86.45(n)1
    96.47(a)1
      5 (48.95 cM)5
    721451  NM_172882.31  NP_766470.21 
     1018329565 
    chicken
    (Gallus gallus)
    Aves WDFY31 WD repeat and FYVE domain containing 3 82.09(n)
    93.19(a)
      422613  XM_420572.2  XP_420572.2 
    lizard
    (Anolis carolinensis)
    Reptilia WDFY36
    WD repeat and FYVE domain containing 3
    91(a)
    1 ↔ 1
    5(43923342-44037663)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.181292 Transcribed sequence with weak similarity to protein more 80.42(n)    BX756198.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.174252 Transcribed sequence with weak similarity to protein more 79.61(n)    BM889904.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bchs1 blue cheese 52.9(n)
    51.11(a)
      33819  NM_135124.1  NP_608968.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C26H9A.21 Protein C26H9A.2 47.82(n)
    39.77(a)
      178220  NM_070019.2  NP_502420.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BPH1(YCR032W)4 PProtein homologous to human Chediak-Higashi syndrome more   --   3(179520-186023) 850398  NP_009961.2 
    rice
    (Oryza sativa)
    Liliopsida Os.232842 Transcribed sequence with moderate similarity to protein more 71.81(n)    CF307340.1 


    ENSEMBL Gene Tree for WDFY3 (if available)
    TreeFam Gene Tree for WDFY3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDFY3 gene
    NSMAF2  LYST2  NBEAL12  WDFY42  LRBA2  NBEA2  NBEAL22  
    6 SIMAP similar genes for WDFY3 using alignment to 6 protein entries:     WDFY3_HUMAN (see all proteins):
    WDF3    NBEAL2    DKFZp686K03100    WDFY4    NBEAL1    LRBA

    WDFY3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5082 SNPs in WDFY3 are shown (see all 5082)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22895941,2
    C,F,H--85590216(+) ACAGCG/AGCTGC 1 -- ds500116Minor allele frequency- A:0.08EA NS WA NA 3818
    rs2021194771,2
    --85590287(+) AAGAG-/ACACACA 1 -- ds50010--------
    rs1447877221,2
    C--85590295(+) CACAC-/ATATATA 1 -- ds50010--------
    rs2015373311,2
    C--85590295(+) ACACAC/TATATA 1 -- ds50010--------
    rs2003580671,2
    C--85590296(+) ATATA-/AT/TA 
            
    CACAC
    1 -- ds50010--------
    rs2005168341,2
    C--85590309(-) TGTGTA/GTATAT 1 -- ds50010--------
    rs1835272241,2
    --85590475(+) CCTGGA/GAATCC 1 -- ds50010--------
    rs1885219501,2
    --85590514(+) AAGCCC/TGATTT 1 -- ds50010--------
    rs2002315011,2
    C--85590732(+) AAATG-/AAAAAA 1 -- ut310--------
    rs1394672351,2
    --85590741(+) AAAAAG/TTACTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for WDFY3 (85590690 - 85840690 bp, first 250kb of WDFY3)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for WDFY3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1008012CNV Insertion20482838
    esv269362CNV Insertion20981092
    nsv879515CNV Loss21882294
    nsv508295CNV Loss20534489
    nsv879516CNV Loss21882294
    nsv527581CNV Loss19592680
    nsv519588CNV Gain19592680


    Human Gene Mutation Database (HGMD): WDFY3
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing WDFY3
    DNA2.0 Custom Variant and Variant Library Synthesis for WDFY3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for WDFY3:    About MalaCards
    chediak-higashi syndrome    paget's disease of bone

    1 disease from the University of Copenhagen DISEASES database for WDFY3:
    Chediak-Higashi syndrome

    WDFY3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): WDFY3
    Human Genome Epidemiology (HuGE) Navigator: WDFY3 (1 document)

    Export disorders for WDFY3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDFY3 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with WDFY3)
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    1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. (PubMed id 15292400)1, 2 Simonsen A.... Stenmark H. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    7. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    8. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    9. Bcl2-associated Athanogene 3 Interactome Analysis Reve als a New Role in Modulating Proteasome Activity. (PubMed id 23824909)1 Chen Y....Ge F. (2013)
    10. Alfy-dependent elimination of aggregated proteins by macroautophagy: can there be too much of a good thing? (PubMed id 21150266)1 Yamamoto A. and Simonsen A. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23001 HGNC: 20751 AceView: WDFY3 Ensembl:ENSG00000163625 euGenes: HUgn23001
    ECgene: WDFY3 H-InvDB: WDFY3

    (According to HUGE)
    About This Section
    HUGE: KIAA0993

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDFY3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDFY3 gene:
    Search GeneIP for patents involving WDFY3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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