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Aliases for WDCP Gene

Aliases for WDCP Gene

  • WD Repeat And Coiled Coil Containing 2 3
  • C2orf44 3 4 5
  • Chromosome 2 Open Reading Frame 44 2 5
  • WD Repeat And Coiled-Coil-Containing Protein 4
  • WD Repeat-Containing Protein C2orf44 3
  • PP384 3

External Ids for WDCP Gene

Previous HGNC Symbols for WDCP Gene

  • C2orf44

Summaries for WDCP Gene

GeneCards Summary for WDCP Gene

WDCP (WD Repeat And Coiled Coil Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDCP Gene

Genomics for WDCP Gene

Regulatory Elements for WDCP Gene

Enhancers for WDCP Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around WDCP on UCSC Golden Path with GeneCards custom track

Promoters for WDCP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around WDCP on UCSC Golden Path with GeneCards custom track

Genomic Location for WDCP Gene

24,029,336 bp from pter
24,049,575 bp from pter
20,240 bases
Minus strand

Genomic View for WDCP Gene

Genes around WDCP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDCP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDCP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDCP Gene

Proteins for WDCP Gene

  • Protein details for WDCP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat and coiled-coil-containing protein C2orf44
    Protein Accession:
    Secondary Accessions:
    • D6W532
    • Q8IYK0
    • Q9HBP5

    Protein attributes for WDCP Gene

    721 amino acids
    Molecular mass:
    79136 Da
    Quaternary structure:
    • Oligomer. Interacts with HCK (via SH3 domain).

    Alternative splice isoforms for WDCP Gene


neXtProt entry for WDCP Gene

Proteomics data for WDCP Gene at MOPED

Post-translational modifications for WDCP Gene

Other Protein References for WDCP Gene

No data available for DME Specific Peptides for WDCP Gene

Domains & Families for WDCP Gene

Protein Domains for WDCP Gene


Suggested Antigen Peptide Sequences for WDCP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 WD repeats.
  • Contains 2 WD repeats.
genes like me logo Genes that share domains with WDCP: view

No data available for Gene Families for WDCP Gene

Function for WDCP Gene

Phenotypes for WDCP Gene

genes like me logo Genes that share phenotypes with WDCP: view

Animal Model Products

miRNA for WDCP Gene

miRTarBase miRNAs that target WDCP

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for WDCP Gene

Localization for WDCP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for WDCP Gene

Pathways & Interactions for WDCP Gene

SuperPathways for WDCP Gene

No Data Available

Gene Ontology (GO) - Biological Process for WDCP Gene


No data available for Pathways by source and SIGNOR curated interactions for WDCP Gene

Drugs & Compounds for WDCP Gene

No Compound Related Data Available

Transcripts for WDCP Gene

mRNA/cDNA for WDCP Gene

Unigene Clusters for WDCP Gene

Chromosome 2 open reading frame 44:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDCP Gene

No ASD Table

Relevant External Links for WDCP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDCP Gene

SOURCE GeneReport for Unigene cluster for WDCP Gene Hs.24624

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for WDCP Gene

Orthologs for WDCP Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDCP Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf44 35
  • 81.37 (n)
  • 75.71 (a)
C2orf44 36
  • 74 (a)
(Canis familiaris)
Mammalia C17H2orf44 35
  • 81.85 (n)
  • 74.16 (a)
C2orf44 36
  • 71 (a)
(Mus musculus)
Mammalia BC068281 35
  • 74.93 (n)
  • 66.98 (a)
BC068281 16
BC068281 36
  • 64 (a)
(Pan troglodytes)
Mammalia C2AH2orf44 35
  • 99.4 (n)
  • 98.89 (a)
C2orf44 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1563701 35
  • 74.3 (n)
  • 64.04 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
-- 36
  • 44 (a)
-- 36
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia C2orf44 36
  • 47 (a)
(Gallus gallus)
Aves LOC421975 35
  • 60.55 (n)
  • 52.87 (a)
C2orf44 36
  • 47 (a)
(Anolis carolinensis)
Reptilia C2orf44 36
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c2orf44 35
  • 57.55 (n)
  • 53.49 (a)
(Danio rerio)
Actinopterygii zgc:103511 35
  • 54.6 (n)
  • 50.54 (a)
C20H2orf44 36
  • 43 (a)
Species with no ortholog for WDCP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDCP Gene

Gene Tree for WDCP (if available)
Gene Tree for WDCP (if available)

Paralogs for WDCP Gene

No data available for Paralogs for WDCP Gene

Variants for WDCP Gene

Sequence variations from dbSNP and Humsavar for WDCP Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs872169 -- 24,036,318(-) ATGTT(C/G)CCTAG intron-variant
rs3215178 -- 24,030,142(-) TTTTT(-/T)AAATC utr-variant-3-prime
rs3731620 -- 24,039,190(-) GCTGA(C/T)GTCTC reference, missense
rs3203 -- 24,029,547(+) GTCAC(C/G/T)GCTCT utr-variant-3-prime
rs3204 -- 24,029,566(+) TGATT(A/G)CAGAC utr-variant-3-prime

Variation tolerance for WDCP Gene

Residual Variation Intolerance Score: 44% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.52; 64.68% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for WDCP Gene

Disorders for WDCP Gene

Relevant External Links for WDCP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDCP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDCP Gene

Publications for WDCP Gene

  1. Molecular characterization of WDCP, a novel fusion partner for the anaplastic lymphoma tyrosine kinase ALK. (PMID: 25469238) Yokoyama N. … Miller W.T. (Biomed. Rep. 2015) 2 3 4 67
  2. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. (PMID: 22327622) Lipson D. … Stephens P.J. (Nat. Med. 2012) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3

Products for WDCP Gene

Sources for WDCP Gene