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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WBSCR22 Gene

protein-coding   GIFtS: 56
GCID: GC07P073097

Williams Beuren Syndrome Chromosome Region 22

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Williams Beuren Syndrome Chromosome Region 221 2     PP33812
Metastasis-Related Methyltransferase 11 2     WBMT2
Williams-Beuren Syndrome Chromosomal Region 22 Protein2 3     Uncharacterized Methyltransferase WBSCR222
HASJ44422     Williams-Beuren Candidate Region Putative Methyltransferase2
HUSSY-32     EC 2.1.1.-3
MERM12     

External Ids:    HGNC: 164051   Entrez Gene: 1140492   Ensembl: ENSG000000714627   UniProtKB: O437093   

Export aliases for WBSCR22 gene to outside databases

Previous GC identifers: GC07P071738 GC07P072496 GC07P072509 GC07P072542 GC07P072735 GC07P068980


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WBSCR22 Gene:
This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif
typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is
deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at
7q11.23. Alternatively spliced transcript variants have been found. (provided by RefSeq, Feb 2011)

GeneCards Summary for WBSCR22 Gene: 
WBSCR22 (Williams Beuren syndrome chromosome region 22) is a protein-coding gene. Diseases associated with WBSCR22 include supravalvular aortic stenosis, and williams-beuren syndrome, and among its related super-pathways are Phenylalanine metabolism. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: WBS22_HUMAN, O43709
Function: Methyltransferase that may act on DNA

Gene Wiki entry for WBSCR22 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007933.15  NT_079593.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WBSCR22 gene promoter:
         AML1a   HNF-4alpha2   STAT5A   Nkx2-5   HNF-4alpha1   Roaz   Max   HOXA5   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWBSCR22 promoter sequence
   Search SABiosciences Chromatin IP Primers for WBSCR22

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WBSCR22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

WBSCR22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WBSCR22 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P073097:  view genomic region     (about GC identifiers)

Start:
73,097,355 bp from pter      End:
73,119,491 bp from pter
Size:
22,137 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 72,430,970-72,445,614     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WBS22_HUMAN, O43709 (See protein sequence)
Recommended Name: Uncharacterized methyltransferase WBSCR22  
Size: 281 amino acids; 31880 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAG17249.1; Type=Frameshift; Positions=194, 203;
Secondary accessions: A8K501 Q96P12 Q9BQ58 Q9HBP9
Alternative splicing: 2 isoforms:  O43709-1   O43709-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for WBSCR22: NX_O43709

Explore proteomics data for WBSCR22 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43709

  • WBSCR22 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WBSCR22 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001189489.1  NP_059998.2  

    ENSEMBL proteins: 
     ENSP00000265758   ENSP00000391761   ENSP00000390136   ENSP00000404981   ENSP00000392039  
     ENSP00000390048   ENSP00000391410   ENSP00000398314   ENSP00000401191   ENSP00000415387  
     ENSP00000398732   ENSP00000394852   ENSP00000397056  

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    Cloud-Clone Corp. Proteins for WBSCR22 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--

    WBSCR22 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR022238 Unchr_MeTrfase_Williams-Beuren
     IPR013216 Methyltransf_11

    Graphical View of Domain Structure for InterPro Entry O43709

    ProtoNet protein and cluster: O43709

    1 Blocks protein domain: IPB013216 Methyltransferase type 11

    UniProtKB/Swiss-Prot: WBS22_HUMAN, O43709
    Similarity: Belongs to the methyltransferase superfamily


    WBSCR22 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WBS22_HUMAN, O43709
    Function: Methyltransferase that may act on DNA

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity NAS11124703
         
    WBSCR22 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for WBSCR22:
     Nucleolar pre-40S maturation d 

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for WBSCR22 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Phenylalanine metabolism
    Tyrosine metabolism0.36
    2Histidine metabolism
    Histidine metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    2         Kegg Pathways  (Kegg details for WBSCR22):
        Histidine metabolism
    Tyrosine metabolism


    WBSCR22 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WBSCR22

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/23 Interacting proteins for WBSCR22 (O437093 ENSP000002657584) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DHX37Q8IY373, ENSP000003111354I2D: score=3 STRING: ENSP00000311135
    BYSLQ138953, ENSP000002303404I2D: score=1 STRING: ENSP00000230340
    PRKAB1Q9Y4783, ENSP000002293284I2D: score=1 STRING: ENSP00000229328
    CNBPP626333I2D: score=1 
    FOSP011003I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0008152metabolic process ----

    WBSCR22 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WBSCR22 (WBS22)

    Search CenterWatch for drugs/clinical trials and news about WBSCR22 / WBS22

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WBSCR22 gene (2 alternative transcripts): 
    NM_001202560.2  NM_017528.4  

    Unigene Cluster for WBSCR22:

    Williams Beuren syndrome chromosome region 22
    Hs.647063  [show with all ESTs]
    Unigene Representative Sequence: BF213257
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000464615 ENST00000265758(uc003tyu.3 uc003tyt.3 uc022afv.1)
    ENST00000421304 ENST00000432522 ENST00000421744(uc010lbi.1) ENST00000478670
    ENST00000496153 ENST00000441822 ENST00000428163 ENST00000436944 ENST00000463307
    ENST00000430270(uc003tyv.3) ENST00000423497 ENST00000487006 ENST00000430446
    ENST00000442099 ENST00000453316 ENST00000471215

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate WBSCR22:
    hsa-miR-576-5p hsa-miR-4263
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    Inhib. RNA
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    Additional mRNA sequence: 

    AF218007.1 AF412034.1 AF420248.1 AK291116.1 AK315032.1 BC000169.2 BC001780.1 BC011696.2 
    NR_037776.2 NR_045512.1 

    24/27 DOTS entries (see all 27):

    DT.95343883  DT.449036  DT.100045556  DT.91697291  DT.100882827  DT.92453336  DT.86853322  DT.100882803 
    DT.86840752  DT.100882800  DT.101985265  DT.40121831  DT.92453315  DT.97835286  DT.100774069  DT.100882797 
    DT.100882799  DT.121099520  DT.121099550  DT.121099594  DT.121099598  DT.75156889  DT.92453326  DT.95343877 

    24/434 AceView cDNA sequences (see all 434):

    CB152593 BU162699 CA773945 BE385255 AA720623 BE390452 BI084123 Z41689 
    CR623973 BC000169 AI423560 AW651736 AL045546 BU155227 CA771385 BQ576234 
    CB242251 AF412034 BQ927478 AA296867 BM672635 BQ066635 BU188540 BG655742 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for WBSCR22 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                                                                                      -           -     -                 -                     
    SP2:                          -     -     -     -                                         -           -     -                 -                     
    SP3:                          -     -     -     -                                                     -     -                 -                     
    SP4:                                -     -     -                                         -                                                         
    SP5:                                                                    -     -           -           -     -                 -                     


    ECgene alternative splicing isoforms for WBSCR22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WBSCR22 expression in normal human tissues (normalized intensities)      WBSCR22 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGCTGGAG
    WBSCR22 Expression
    About this image


    WBSCR22 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Kidney (Urinary System)
             renal vesicle e12.5   
     
     Gonad
             XY Germ Cells Testis Cord

    See WBSCR22 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WBSCR22

    SOURCE GeneReport for Unigene cluster: Hs.647063

    UniProtKB/Swiss-Prot: WBS22_HUMAN, O43709
    Tissue specificity: Strongly expressed in heart, skeletal muscle and kidney. Also expressed in spleen, liver, lung
    and testis

        SABiosciences Expression via Pathway-Focused PCR Array including WBSCR22: 
              Amino Acid Metabolism II in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WBSCR22 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wbscr221 , 5 Williams Beuren syndrome chromosome region 221, 5 82.68(n)1
    79.72(a)1
      5 (74.97 cM)5
    661381  NM_025375.31  NP_079651.21 
     1350529575 
    chicken
    (Gallus gallus)
    Aves WBSCR221 Williams Beuren syndrome chromosome region 22 70.46(n)
    70.46(a)
      431053  NM_001039332.1  NP_001034421.1 
    lizard
    (Anolis carolinensis)
    Reptilia WBSCR226
    Uncharacterized protein
    69(a)
    1 ↔ 1
    GL343734.1(229210-242735)
    zebrafish
    (Danio rerio)
    Actinopterygii wbscr221 Williams Beuren syndrome chromosome region 22 68.33(n)
    66.55(a)
      572367  NM_001082879.1  NP_001076348.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG109031 CG10903 59.22(n)
    60.44(a)
      40952  NM_141505.3  NP_649762.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C27F2.41 Protein C27F2.4 54.17(n)
    54.29(a)
      175671  NM_065650.2  NP_498051.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BUD23(YCR047C)4
    BUD231
    Methyltransferase, methylates residue G1575 of 18S more4
    Bud23p1
    53.21(n)1
    50(a)1
      3(211545-210718)4
    8504141, 4  NP_009976.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G572801 S-adenosyl-L-methionine-dependent methyltransferase-like more 55.2(n)
    52.98(a)
      835833  NM_125110.5  NP_200538.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g08043001 hypothetical protein 57.61(n)
    54.7(a)
      4331056  NM_001054967.1  NP_001048432.1 


    ENSEMBL Gene Tree for WBSCR22 (if available)
    TreeFam Gene Tree for WBSCR22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/310 SNPs in WBSCR22 are shown (see all 310)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1883361091,2
    --73099819(+) TCTATC/TGCCCA 4 -- int10--------
    rs1823572511,2
    --73099837(+) GTGCTA/GCAGTG 4 -- int10--------
    rs1853967791,2
    --73099899(+) CCCGAA/CTAGTT 4 -- int10--------
    rs352018751,2
    C--73100266(+) AAAAAA/-TTAGC 4 -- int11Minor allele frequency- -:0.00NA 2
    rs1435740651,2
    --73100350(+) TAACCC/TGGGAG 4 -- int10--------
    rs357032061,2
    C--73100429(+) GTCTC-/AAAAAA 4 -- int12Minor allele frequency- A:0.00NA CSA 4
    rs117621911,2
    C,F,A,H--73100487(+) TTCTTG/CACTGG 4 -- int111Minor allele frequency- C:0.47NA WA CSA EA 374
    rs755306541,2
    C,F--73100588(+) GAAACT/CATGGA 4 -- int11Minor allele frequency- C:0.05WA 118
    rs1906452051,2
    --73100637(+) AGCAGC/TCCAGC 4 -- int10--------
    rs21411671,2
    C,F,A,H--73100724(-) TATCAT/CTGCAC 4 -- int110Minor allele frequency- C:0.17NS EA NA CSA WA 782

    HapMap Linkage Disequilibrium report for WBSCR22 (73097355 - 73119491 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for WBSCR22:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831028CNV Loss17160897
    nsv888371CNV Loss21882294
    nsv888370CNV Loss21882294
    dgv7325n71CNV Loss21882294
    nsv469841CNV Complex16826518

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    UniProtKB/Swiss-Prot: WBS22_HUMAN, O43709
  • Note=WBSCR22 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a
    hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing
    over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of
    WBSCR22 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease

  • 5 diseases for WBSCR22:    About MalaCards
    supravalvular aortic stenosis    williams-beuren syndrome    williams syndrome    parkinson's disease
    gastric cancer

    2 diseases from the University of Copenhagen DISEASES database for WBSCR22:
    Williams-Beuren syndrome     Supravalvular aortic stenosis

    WBSCR22 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for WBSCR22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WBSCR22 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with WBSCR22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome. (PubMed id 11978965)1, 2, 3, 9 Doll A. and Grzeschik K.-H. (2001)
    2. Identification of additional transcripts in the Williams-Beuren syndrome critical region. (PubMed id 12073013)1, 2, 3 Merla G....Reymond A. (2002)
    3. The novel metastasis promoter Merm1/Wbscr22 enhances t umor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosi s. (PubMed id 21148752)1, 3 Nakazawa Y....Fujita N. (2011)
    4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    8. Characterization of 16 novel human genes showing high similarity to yeast sequences. (PubMed id 11124703)1, 2 Stanchi F.... Valle G. (2001)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 114049 HGNC: 16405 AceView: WBSCR22 Ensembl:ENSG00000071462 euGenes: HUgn114049
    ECgene: WBSCR22 Kegg: 114049 H-InvDB: WBSCR22

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WBSCR22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WBSCR22 gene:
    Search GeneIP for patents involving WBSCR22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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