Aliases for WBP2 Gene
External Ids for WBP2 Gene
Previous GeneCards Identifiers for WBP2 Gene
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]
GeneCards Summary for WBP2 Gene
WBP2 (WW Domain Binding Protein 2) is a Protein Coding gene. Among its related pathways are Wnt / Hedgehog / Notch and Tyrosine Kinases / Adaptors. GO annotations related to this gene include RNA polymerase II core promoter sequence-specific DNA binding and RNA polymerase II transcription coactivator activity. An important paralog of this gene is WBP2NL.