Aliases for WARS2 Gene
External Ids for WARS2 Gene
Previous GeneCards Identifiers for WARS2 Gene
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for WARS2 Gene
WARS2 (Tryptophanyl TRNA Synthetase 2, Mitochondrial) is a Protein Coding gene. Diseases associated with WARS2 include Autosomal Recessive Non-Syndromic Intellectual Disability and Long Qt Syndrome 1. Among its related pathways are tRNA Aminoacylation and Gene Expression. GO annotations related to this gene include nucleotide binding and tryptophan-tRNA ligase activity.