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Aliases for VWA8 Gene

Aliases for VWA8 Gene

  • Von Willebrand Factor A Domain Containing 8 2 3
  • KIAA0564 2 3 4
  • Von Willebrand Factor A Domain-Containing Protein 8 3

External Ids for VWA8 Gene

Previous HGNC Symbols for VWA8 Gene

  • KIAA0564

Previous GeneCards Identifiers for VWA8 Gene

  • GC13M042141

Summaries for VWA8 Gene

GeneCards Summary for VWA8 Gene

VWA8 (Von Willebrand Factor A Domain Containing 8) is a Protein Coding gene. GO annotations related to this gene include ATPase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VWA8 Gene

Genomics for VWA8 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for VWA8 Gene

41,566,825 bp from pter
41,961,120 bp from pter
394,296 bases
Minus strand

Genomic View for VWA8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VWA8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VWA8 Gene

No data available for Regulatory Elements for VWA8 Gene

Proteins for VWA8 Gene

  • Protein details for VWA8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    von Willebrand factor A domain-containing protein 8
    Protein Accession:
    Secondary Accessions:
    • O60310
    • Q5JTP6
    • Q5VW08
    • Q7Z6I9
    • Q86YC9
    • Q8N3E4

    Protein attributes for VWA8 Gene

    1905 amino acids
    Molecular mass:
    214824 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for VWA8 Gene


neXtProt entry for VWA8 Gene

Proteomics data for VWA8 Gene at MOPED

Post-translational modifications for VWA8 Gene

  • Glycosylation at Asn284, Asn855, Asn1096, Asn1142, and Asn1833
  • Modification sites at PhosphoSitePlus

Other Protein References for VWA8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VWA8 Gene

Domains for VWA8 Gene

Protein Domains for VWA8 Gene

Graphical View of Domain Structure for InterPro Entry



  • A3KMH1
  • Contains 1 VWFA domain.
genes like me logo Genes that share domains with VWA8: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for VWA8 Gene

Function for VWA8 Gene

Gene Ontology (GO) - Molecular Function for VWA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
GO:0016887 ATPase activity IEA --
genes like me logo Genes that share ontologies with VWA8: view

Animal Model Products

miRNA for VWA8 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VWA8

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for VWA8 Gene

Localization for VWA8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VWA8 Gene


Gene Ontology (GO) - Cellular Components for VWA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with VWA8: view

No data available for Subcellular locations from COMPARTMENTS for VWA8 Gene

Pathways for VWA8 Gene

SuperPathways for VWA8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for VWA8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006200 obsolete ATP catabolic process --
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with VWA8: view

No data available for Pathways by source for VWA8 Gene

Transcripts for VWA8 Gene

Unigene Clusters for VWA8 Gene

Von Willebrand factor A domain containing 8:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VWA8

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VWA8 Gene

No ASD Table

Relevant External Links for VWA8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VWA8 Gene

mRNA expression in normal human tissues for VWA8 Gene

Protein differential expression in normal tissues for VWA8 Gene

This gene is overexpressed in Kidney (11.5), Salivary gland (7.9), Stomach (6.6), Lymph node (6.4), and Liver (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for VWA8 Gene

SOURCE GeneReport for Unigene cluster for VWA8 Gene Hs.368282

genes like me logo Genes that share expressions with VWA8: view

Expression partners for VWA8 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for VWA8 Gene

Orthologs for VWA8 Gene

This gene was present in the common ancestor of animals.

Orthologs for VWA8 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia VWA8 35
  • 89.07 (n)
  • 91.79 (a)
VWA8 36
  • 88 (a)
(Canis familiaris)
Mammalia VWA8 35
  • 90.48 (n)
  • 91.82 (a)
VWA8 36
  • 92 (a)
(Mus musculus)
Mammalia Vwa8 35
  • 83.33 (n)
  • 86.24 (a)
Vwa8 16
Vwa8 36
  • 86 (a)
(Pan troglodytes)
Mammalia VWA8 35
  • 99.49 (n)
  • 99.32 (a)
VWA8 36
  • 99 (a)
(Monodelphis domestica)
Mammalia VWA8 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia VWA8 36
  • 74 (a)
(Gallus gallus)
Aves KIAA0564 35
  • 74.94 (n)
  • 79.06 (a)
VWA8 36
  • 78 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 76 (a)
-- 36
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17650 35
vwa8 35
  • 71.76 (n)
  • 76.23 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC68485 35
(Danio rerio)
Actinopterygii vwa8 35
  • 67.22 (n)
  • 72.12 (a)
vwa8 36
  • 71 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000545 35
  • 54.58 (n)
  • 55.76 (a)
fruit fly
(Drosophila melanogaster)
Insecta c12.2 35
  • 55.09 (n)
  • 54.68 (a)
c12.2 36
  • 52 (a)
(Caenorhabditis elegans)
Secernentea F11C1.5 35
  • 49.46 (n)
  • 41.04 (a)
F11C1.5 36
  • 38 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.972 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4168 36
  • 54 (a)
Species with no ortholog for VWA8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for VWA8 Gene

Gene Tree for VWA8 (if available)
Gene Tree for VWA8 (if available)

Paralogs for VWA8 Gene Pseudogenes for VWA8 Gene

genes like me logo Genes that share paralogs with VWA8: view

No data available for Paralogs for VWA8 Gene

Variants for VWA8 Gene

Sequence variations from dbSNP and Humsavar for VWA8 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs13862 -- 41,567,569(-) TGGAG(C/T)GCTTG utr-variant-3-prime
rs348238 -- 41,567,634(+) GCCAG(A/C)CTTTC utr-variant-3-prime
rs348256 -- 41,591,859(-) caaca(A/G)tgtaa intron-variant
rs348257 -- 41,591,218(+) TGCAA(A/G)TGGAA intron-variant
rs412731 -- 41,573,488(+) AAAAa(A/T)atata intron-variant

Relevant External Links for VWA8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for VWA8 Gene

Disorders for VWA8 Gene

No disorders were found for VWA8 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for VWA8 Gene

Publications for VWA8 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  2. Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PMID: 12421765) Nakayama M. … Ohara O. (Genome Res. 2002) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for VWA8 Gene

Sources for VWA8 Gene

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