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Aliases for VWA7 Gene

Aliases for VWA7 Gene

  • Von Willebrand Factor A Domain Containing 7 2 3
  • C6orf27 3 4 6
  • G7c 3 4 6
  • Protein G7c 3 4
  • NG37 3 4
  • Von Willebrand Factor A Domain-Containing Protein 7 3
  • Chromosome 6 Open Reading Frame 27 2

External Ids for VWA7 Gene

Previous HGNC Symbols for VWA7 Gene

  • C6orf27

Previous GeneCards Identifiers for VWA7 Gene

  • GC06M031740

Summaries for VWA7 Gene

GeneCards Summary for VWA7 Gene

VWA7 (Von Willebrand Factor A Domain Containing 7) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VWA7 Gene

Genomics for VWA7 Gene

Genomic Location for VWA7 Gene

Start:
31,765,401 bp from pter
End:
31,777,331 bp from pter
Size:
11,931 bases
Orientation:
Minus strand

Genomic View for VWA7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VWA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for VWA7 Gene

Proteins for VWA7 Gene

  • Protein details for VWA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y334-VWA7_HUMAN
    Recommended name:
    von Willebrand factor A domain-containing protein 7
    Protein Accession:
    Q9Y334
    Secondary Accessions:
    • A2BEX8
    • A6NHR6
    • B0V041
    • Q5SSR5
    • Q96QC8
    • Q9UMP9

    Protein attributes for VWA7 Gene

    Size:
    891 amino acids
    Molecular mass:
    96060 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Found in the major hispocompatibility complex class III region. May be implicated in susceptibility to lung tumors
    SequenceCaution:
    • Sequence=CAB52192.1; Type=Frameshift; Positions=553, 559, 783; Evidence={ECO:0000305};

    Alternative splice isoforms for VWA7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for VWA7 Gene

Proteomics data for VWA7 Gene at MOPED

Post-translational modifications for VWA7 Gene

  • Glycosylation at Asn55 and Asn781
  • Modification sites at PhosphoSitePlus

Other Protein References for VWA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VWA7 Gene

Domains for VWA7 Gene

Protein Domains for VWA7 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y334

UniProtKB/Swiss-Prot:

VWA7_HUMAN :
  • Q9Y334
Domain:
  • Contains 1 VWFA domain.
genes like me logo Genes that share domains with VWA7: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for VWA7 Gene

Function for VWA7 Gene

Gene Ontology (GO) - Molecular Function for VWA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with VWA7: view

Phenotypes for VWA7 Gene

GenomeRNAi human phenotypes for VWA7:
genes like me logo Genes that share phenotypes with VWA7: view

Animal Model Products

CRISPR Products

miRNA for VWA7 Gene

miRTarBase miRNAs that target VWA7

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for VWA7 Gene

Localization for VWA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VWA7 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for VWA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with VWA7: view

No data available for Subcellular locations from COMPARTMENTS for VWA7 Gene

Pathways for VWA7 Gene

SuperPathways for VWA7 Gene

No Data Available

Interacting Proteins for VWA7 Gene

Gene Ontology (GO) - Biological Process for VWA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with VWA7: view

No data available for Pathways by source for VWA7 Gene

Transcripts for VWA7 Gene

Unigene Clusters for VWA7 Gene

Von Willebrand factor A domain containing 7:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VWA7

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for VWA7
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VWA7 Gene

No ASD Table

Relevant External Links for VWA7 Gene

GeneLoc Exon Structure for
VWA7
ECgene alternative splicing isoforms for
VWA7

Expression for VWA7 Gene

mRNA expression in normal human tissues for VWA7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for VWA7 Gene

This gene is overexpressed in Pituitary (10.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for VWA7 Gene

SOURCE GeneReport for Unigene cluster for VWA7 Gene Hs.558553

mRNA Expression by UniProt/SwissProt for VWA7 Gene

Q9Y334-VWA7_HUMAN
Tissue specificity: Expressed at low level in different cell lines.
genes like me logo Genes that share expressions with VWA7: view

In Situ Assay Products

Orthologs for VWA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for VWA7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia VWA7 35
  • 99.25 (n)
  • 98.43 (a)
VWA7 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia VWA7 35
  • 86.23 (n)
  • 85.67 (a)
VWA7 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia VWA7 35
  • 85.68 (n)
  • 84.22 (a)
VWA7 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Vwa7 35
  • 83.26 (n)
  • 82.36 (a)
Vwa7 16
Vwa7 36
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia VWA7 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia VWA7 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Vwa7 35
  • 82.45 (n)
  • 81.21 (a)
lizard
(Anolis carolinensis)
Reptilia VWA7 36
  • 38 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia vwa7 35
  • 52.6 (n)
  • 45.49 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch73-235d11.1 35
  • 50.15 (n)
  • 44.01 (a)
VWA7 36
  • 30 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
OneToOne
Species with no ortholog for VWA7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VWA7 Gene

ENSEMBL:
Gene Tree for VWA7 (if available)
TreeFam:
Gene Tree for VWA7 (if available)

Paralogs for VWA7 Gene

No data available for Paralogs for VWA7 Gene

Variants for VWA7 Gene

Sequence variations from dbSNP and Humsavar for VWA7 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs707928 -- 31,774,813(-) AGCCC(C/T)AGTTT intron-variant
rs707929 -- 31,774,290(-) GGCAG(C/T)TTTGG intron-variant
rs707930 -- 31,773,882(-) ccacc(A/G)tgccc intron-variant
rs707931 -- 31,772,226(-) tgagg(C/T)tgcag intron-variant
rs707932 -- 31,770,566(-) gagat(A/G)gagtc intron-variant

Relevant External Links for VWA7 Gene

HapMap Linkage Disequilibrium report
VWA7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for VWA7 Gene

Disorders for VWA7 Gene

No disorders were found for VWA7 Gene.

No data available for UniProtKB/Swiss-Prot for VWA7 Gene

Publications for VWA7 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3 4
  3. G7c, a novel gene in the mouse and human major histocompatibility complex class III region, possibly controlling lung tumor susceptibility. (PMID: 10803853) Snoek M. … Campbell R.D. (Immunogenetics 2000) 3 4
  4. G7c in the lung tumor susceptibility (Lts) region of the Mhc class III region encodes a von Willebrand factor type A domain protein. (PMID: 11261934) KumA!novics A. … Lindahl K.F. (Immunogenetics 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for VWA7 Gene

Sources for VWA7 Gene

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