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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

VWA5A Gene

protein-coding GIFtS: 44
GCID: GC11P123987

von Willebrand factor A domain containing 5A

(Previous names: loss of heterozygosity, 11, chromosomal region 2, gene...)
(Previous symbol: LOH11CR2A)

Explore 4 diseases affiliated with
VWA5A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Von Willebrand Factor A Domain Containing 5A¹ ²		Breast Cancer Suppressor Candidate 1² ³
LOH11CR2A¹ ² ³ ⁵		Loss Of Heterozygosity 11 Chromosomal Region 2 Gene A Protein² ³
BCSC-1¹ ² ³		Ortholog Of Mouse AW551984²
BCSC1² ³ ⁵		Von Willebrand Factor A Domain-Containing Protein 5A²
Loss Of Heterozygosity, 11, Chromosomal Region 2, Gene A¹ ²

External Ids:	HGNC: 6658¹	Entrez Gene: 4013²	Ensembl: ENSG00000110002⁷	OMIM: 602929⁵	UniProtKB: O00534³

Export aliases for VWA5A gene to outside databases

Previous GC identifers: GC11P123492 GC11P119926

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: VMA5A_HUMAN, O00534

Function: May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of

the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the VWA5A gene promoter:
LHX3b/Lhx3b C/EBPbeta FOXD3 Olf-1 Gfi-1 AREB6 PPAR-gamma1 HOXA5 Cart-1 PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VWA5A promoter sequence

Search SABiosciences Chromatin IP Primers for VWA5A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VWA5A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.1 Ensembl cytogenetic band: 11q24.2 HGNC cytogenetic band: 11q24.1

VWA5A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VWA5A gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P123987: view genomic region (about GC identifiers)

Start:	123,986,069 bp from pter	End:	124,018,428 bp from pter
Size:	32,360 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VMA5A_HUMAN, O00534 (See protein sequence)

Recommended Name: von Willebrand factor A domain-containing protein 5A

Size: 786 amino acids; 86489 Da

Secondary accessions: Q6UN19 Q6UN20 Q9BVF8

Alternative splicing: 4 isoforms: O00534-1 O00534-2 O00534-3 O00534-4

Explore the universe of human proteins at neXtProt for VWA5A: NX_O00534

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O00534

VWA5A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001123614.1 NP_055437.2 NP_938057.1

ENSEMBL proteins:

ENSP00000407726 ENSP00000355070 ENSP00000404683 ENSP00000432231 ENSP00000431452

ENSP00000376501 ENSP00000376504 ENSP00000353485

Human Recombinant Protein Products for VWA5A:

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	Novus Biologicals VWA5A Proteins Novus Biologicals VWA5A Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for VWA5A

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--

VWA5A for ontologies About GeneDecksing

VWA5A Antibody Products:

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	Uscn Antibodies for VWA5A
	Search ThermoFisher Antibodies for VWA5A

Assay Products for VWA5A:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for VWA5A
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	Uscn ELISAs and CLIAs for VWA5A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

VWA5A for domains About GeneDecksing

2 InterPro domains/families:

IPR013694 VIT

IPR002035 VWF_A

Graphical View of Domain Structure for InterPro Entry O00534

ProtoNet protein and cluster: O00534

UniProtKB/Swiss-Prot: VMA5A_HUMAN, O00534

Similarity: Contains 1 VIT domain

Similarity: Contains 1 VWFA domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: VMA5A_HUMAN, O00534

Function: May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of

the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for VWA5A

miRNA Products:		OriGene 3'-UTR Clone (see all 3): VWA5A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VWA5A
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate VWA5A:
		hsa-miR-515-5p hsa-miR-4314 hsa-miR-519e*
		SwitchGear 3'UTR luciferase reporter plasmid: VWA5A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VWA5A (see all 4) OriGene shRNA RFP: VWA5A OriGene siRNA: VWA5A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VWA5A
		Sirion Biotech Custom design and validation of potent shRNA sequences against VWA5A

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for VWA5A
			Sirion Biotech Customized adenovirus for overexpression of VWA5A Sirion Biotech Customized adenovirus for potent knockdown of VWA5A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VWA5A (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VWA5A (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): VWA5A (NM_001130142)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VWA5A
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for VWA5A
		Search LifeMap BioReagents cell lines for VWA5A
		Sirion Biotech Customized stable knockdown cell line services for VWA5A Sirion Biotech Customized inducible knockdown cell line services for VWA5A Sirion Biotech Customized stable overexpressing cell line services for VWA5A Sirion Biotech Customized inducible overexpressing cell line services for VWA5A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VWA5A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for VWA5A

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for VWA5A (ENSP00000376504⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for VWA5A
Search CenterWatch for drugs/clinical trials and news about VWA5A / VMA5A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for VWA5A gene (3 alternative transcripts):

NM_001130142.1 NM_014622.4 NM_198315.2

Unigene Cluster for VWA5A:

Von Willebrand factor A domain containing 5A

Hs.152944 [show with all ESTs]

Unigene Representative Sequence: NM_001130142

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000456829(uc001pzu.3 uc001pzt.3) ENST00000361352(uc001pzr.3)

ENST00000449321(uc001pzs.3 uc010sae.2) ENST00000524524 ENST00000530025

ENST00000392744 ENST00000533623 ENST00000392748 ENST00000360334

miRNA Products:		OriGene 3'-UTR Clone (see all 3): VWA5A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VWA5A
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate VWA5A:
		hsa-miR-515-5p hsa-miR-4314 hsa-miR-519e*
		SwitchGear 3'UTR luciferase reporter plasmid: VWA5A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VWA5A (see all 4) OriGene shRNA RFP: VWA5A OriGene siRNA: VWA5A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VWA5A
		Sirion Biotech Custom design and validation of potent shRNA sequences against VWA5A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VWA5A (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VWA5A (see all 4) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): VWA5A (NM_001130142)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VWA5A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VWA5A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VWA5A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat VWA5A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VWA5A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VWA5A

Additional cDNA sequence:

AF002672.1 AK291698.1 AK295247.1 AK314934.1 AY366503.1 AY366504.1 AY366505.1 AY366506.1

AY366507.1 AY366508.1 BC001234.1 BT006655.1

14 DOTS entries:

DT.100783388 DT.411752 DT.100783387 DT.101980471 DT.120685663 DT.100783385 DT.120685664 DT.100783386

DT.97769769 DT.97841319 DT.100644637 DT.102826375 DT.102826376 DT.120685683

24/123 AceView cDNA sequences (see all 123):

CA952694 NM_014622 BU619632 BU633353 CR599674 AL548501 BT006655 CA424211

BP338115 AI564882 BM768378 AY366508 BI255861 BE856012 CA952446 AU279509

AU131195 AY366505 BI757746 BU618586 BM981561 AA534528 BC001234 AL541683

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for VWA5A (see all 8) About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19
SP1:					-						-																				-
SP2:			-		-						-																				-
SP3:					-						-
SP4:			-		-						-
SP5:					-						-												-		-		-		-		-		-		-		-		-		-		-		-

ECgene alternative splicing isoforms for VWA5A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

VWA5A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAACACCTTA

About this image

VWA5A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)

Cartilage, Neural Crest

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See VWA5A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VWA5A

SOURCE GeneReport for Unigene cluster: Hs.152944

UniProtKB/Swiss-Prot: VMA5A_HUMAN, O00534

Tissue specificity: Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested

SABiosciences Custom PCR Arrays for VWA5A

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VWA5A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VWA5A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for VWA5A gene from 4/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	VWA5A⁶	Uncharacterized protein	33(a)	1 ↔ 1	27(61775-69431)
lizard (Anolis carolinensis)	Reptilia	-- --	--	44(a) 38(a)	1 ↔ many 1 ↔ many	GL343253.1(1791085-1813620) GL343253.1(1882641-1896787)
African clawed frog (Xenopus laevis)	Amphibia	MGC68953²	hypothetical protein MGC68953	73.96(n)		BC057735.1
zebrafish (Danio rerio)	Actinopterygii	LOC100535146¹	von Willebrand factor A domain-containing protein 5A-like	54.57(n) 47.29(a)		100535146 XM_003201390.1 XP_003201438.1

ENSEMBL Gene Tree for VWA5A (if available)
TreeFam Gene Tree for VWA5A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for VWA5A gene

PARP4² VWA5B1² VWA5B2²

VWA5A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs80328531^1,2	F	--	123984177(+)	`TTAGGG/ATAAGA`	3	--	us2k¹		1		EA	120
rs184031577^1,2		--	123984255(+)	`GATACA/GGTGGC`	3	--	us2k¹		0	--	--	--	--
rs10790634^1,2	C,F,A,H	--	123984528(+)	`AGGCTG/AGGCAA`	3	--	us2k¹		12		NA WA CSA EA	374
rs1939849^1,2	C,H	--	123984666(+)	`CATCTA/TTATCG`	3	--	us2k¹ tfbs³		15		MN NS EA NA WA CSA	613
rs188761878^1,2		--	123984671(+)	`TTATCA/GGTTTA`	3	--	us2k¹		0	--	--	--	--
rs56923449^1,2	C	--	123984683(+)	`TTGTGT/CATATT`	3	--	us2k¹		2		WA	120
rs180781425^1,2		--	123984735(+)	`AACCAG/TCAACT`	3	--	us2k¹		0	--	--	--	--
rs4936893^1,2	C,F,A,H	--	123984748(+)	`TGTGTG/ATTTCC`	3	--	us2k¹		21		NS EA NA	2648
rs186217637^1,2		--	123984783(+)	`TGCATG/TCCTGG`	3	--	us2k¹		0	--	--	--	--
rs190339533^1,2		--	123984851(+)	`TGCCCA/GCGTTT`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for VWA5A (123986069 - 124018428 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for VWA5A: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VWA5A

DNA2.0 Custom Variant and Variant Library Synthesis for VWA5A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

VWA5A for disorders           About GeneDecksing

OMIM gene information: 602929    OMIM disorders: --

4 diseases for VWA5A:    About MalaCards

breast cancer nasopharynx carcinoma nasopharyngitis carcinoma

Export disorders for VWA5A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for VWA5A gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with VWA5A)

Utopia: connect your pdf to the dynamic
world of online information

The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene. (PubMed id 14504409)^{1, 2, 3} Martin E.S....Croce C.M. (2003)
Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23. (PubMed id 9417908)^{1, 2, 3} Monaco C.... Croce C.M. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Breast cancer suppressor candidate-1 (BCSC-1) is a mel anoma tumor suppressor that down regulates MITF. (PubMed id 22594792)¹ Anghel S.I....Piguet V. (2012)
A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)¹ Shi Y....Qin J. (2011)
A genome-wide association study of aging. (PubMed id 21782286)¹ Walter S....Franceschini N. (2011)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Frequent alterations of LOH11CR2A, PIG8 and CHEK1 gene s at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognosti c implications. (PubMed id 21803008)¹ Sinha S....Panda C.K. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 4013	HGNC: 6658	AceView: LOH11CR2A	Ensembl:ENSG00000110002	euGenes: HUgn4013
ECgene: VWA5A	H-InvDB: VWA5A

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for VWA5A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for VWA5A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for VWA5A gene:
Search GeneIP for patents involving VWA5A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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VWA5A Gene

von Willebrand factor A domain containing 5A

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VWA5A Gene

von Willebrand factor A domain containing 5A

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External Searches for VWA5A gene

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Specialized Databases showing VWA5A gene

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for VWA5A gene

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Intellectual Property
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