Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

VWA3A Gene

protein-coding GIFtS: 38
GCID: GC16P022103

Von Willebrand Factor A Domain Containing 3A

Search for VWA3A
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Von Willebrand Factor A Domain Containing 3A¹ ²
Von Willebrand Factor A Domain-Containing Protein 3A²

External Ids:	HGNC: 27088¹	Entrez Gene: 146177²	Ensembl: ENSG00000175267⁷	UniProtKB: A6NCI4³

Export aliases for VWA3A gene to outside databases

Previous GC identifers: GC16P022015 GC16P020349

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for VWA3A Gene:

VWA3A (von Willebrand factor A domain containing 3A) is a protein-coding gene. An important paralog of this gene is VWA3B.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NT_010393.16 NC_018927.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the VWA3A gene promoter:
c-Fos SRY AP-1 Pbx1a POU2F1 POU2F1a FosB c-Jun MRF-2 Evi-1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for VWA3A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VWA3A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2 Ensembl cytogenetic band: 16p12.2 HGNC cytogenetic band: 16p12.1

VWA3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VWA3A gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16P022103: view genomic region (about GC identifiers)

Start:	22,103,859 bp from pter	End:	22,168,287 bp from pter
Size:	64,429 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VWA3A_HUMAN, A6NCI4 (See protein sequence)

Recommended Name: von Willebrand factor A domain-containing protein 3A precursor

Size: 1184 amino acids; 134020 Da

Subcellular location: Secreted (Potential)

Secondary accessions: A4QMU8 A6NNC0 Q6UTX4 Q6ZQZ9 Q8IUY6 Q8N9W1

Alternative splicing: 4 isoforms: A6NCI4-1 A6NCI4-2 A6NCI4-3 A6NCI4-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VWA3A: NX_A6NCI4

Explore proteomics data for VWA3A at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_A6NCI4

VWA3A Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_775886.3

ENSEMBL proteins:

ENSP00000457368 ENSP00000457770 ENSP00000374049 ENSP00000299840 ENSP00000457167

ENSP00000456513 ENSP00000374048

Human Recombinant Protein Products for VWA3A:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for VWA3A OriGene Custom MassSpec OriGene Custom Protein Services for VWA3A
	GenScript Custom Purified and Recombinant Proteins Services for VWA3A
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

VWA3A for ontologies About GeneDecksing

VWA3A Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for VWA3A
	GenScript Custom Superior Antibodies Services for VWA3A
	Novus Biologicals VWA3A Antibodies
	Search for Antibodies for VWA3A at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibodies for VWA3A
	Search LSBio for Antibodies for VWA3A

Assay Products for VWA3A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for VWA3A
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for VWA3A
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro protein domain:

IPR002035 VWF_A

Graphical View of Domain Structure for InterPro Entry A6NCI4

ProtoNet protein and cluster: A6NCI4

UniProtKB/Swiss-Prot: VWA3A_HUMAN, A6NCI4

Similarity: Contains 2 VWFA domains

VWA3A for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for VWA3A

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for VWA3A

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VWA3A

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VWA3A

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VWA3A
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate VWA3A (see all 10):
		hsa-miR-31 hsa-miR-4303 hsa-miR-550a hsa-miR-4251 hsa-miR-4312 hsa-miR-520a-5p hsa-miR-3160-3p hsa-miR-525-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for VWA3A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VWA3A

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for VWA3A
			Sirion Biotech Customized adenovirus for overexpression of VWA3A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for VWA3A (see all 10) OriGene ORF clones in mouse, rat for VWA3A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: VWA3A (NM_173615)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VWA3A
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VWA3A
		Sirion Biotech Customized lentivirus for stable overexpression of VWA3A Customized lentivirus expression plasmids for stable overexpression of VWA3A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for VWA3A
		Search LifeMap BioReagents cell lines for VWA3A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VWA3A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for VWA3A

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for VWA3A

Search CenterWatch for drugs/clinical trials and news about VWA3A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for VWA3A gene (2 alternative transcripts):

NM_175059.2 NM_173615.3

Unigene Cluster for VWA3A:

Von Willebrand factor A domain containing 3A

Hs.10697 [show with all ESTs]

Unigene Representative Sequence: NM_173615

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000562340 ENST00000567131 ENST00000566668 ENST00000568328 ENST00000389398(uc010bxc.2 uc010vbq.2 uc010bxd.3 uc002dkg.4)

ENST00000299840 ENST00000563389 ENST00000563755 ENST00000389397(uc010bxe.1)

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VWA3A
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate VWA3A (see all 10):
		hsa-miR-31 hsa-miR-4303 hsa-miR-550a hsa-miR-4251 hsa-miR-4312 hsa-miR-520a-5p hsa-miR-3160-3p hsa-miR-525-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for VWA3A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VWA3A

Clone Products:		OriGene clones in human, mouse for VWA3A (see all 10) OriGene ORF clones in mouse, rat for VWA3A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: VWA3A (NM_173615)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VWA3A
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VWA3A
		Sirion Biotech Customized lentivirus for stable overexpression of VWA3A Customized lentivirus expression plasmids for stable overexpression of VWA3A

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for VWA3A
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat VWA3A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VWA3A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VWA3A

Additional mRNA sequence:

AK093467.1 AK128606.1 AK307544.1 AY360464.1 BC038400.1 BC109294.1 BC109295.1

8 DOTS entries:

DT.407129 DT.99998669 DT.100019005 DT.120658560 DT.120658938 DT.91923781 DT.120658787 DT.91666892

24/32 AceView cDNA sequences (see all 32):

CB241886 BF739772 BC038400 BU684516 N47075 AY360464 BX114698 BU683697

AK093467 BM998658 AK128606 AK098260 AI016658 CB241369 AA781930 AX748144

BE466460 BI916787 AA398185 BI755006 AI192034 BG570684 BI035585 CD705779

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for VWA3A About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19a	·	19b	^	20	^	21a	·	21b	^	22	^	23	^
SP1:																																							-
SP2:									-																-
SP3:
SP4:					-				-
SP5:					-

ExUns:	24	^	25a	·	25b	^	26	^	27	^	28	^	29	^	30	^	31	^	32	^	33a	·	33b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for VWA3A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

VWA3A expression in normal human tissues (normalized intensities) VWA3A embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ACTTTAACTG

About this image

VWA3A expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/2 selected tissues (see all 2) fully expand


Epithelium (Respiratory System) fully expand to see all 2 entries
bronchial epithelial cells

Pancreas (Endocrine System)
Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...

See VWA3A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VWA3A

SOURCE GeneReport for Unigene cluster: Hs.10697

SABiosciences Custom PCR Arrays for VWA3A

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for VWA3A
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat VWA3A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VWA3A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VWA3A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VWA3A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for VWA3A gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Vwa3a^{1 , 5}	von Willebrand factor A domain containing 3A^{1, 5}	79.62(n)¹ 73.35(a)¹		7 (64.90 cM)⁵ 233813¹ NM_177697.3¹ NP_808365.2¹ 120739557⁵
chicken (Gallus gallus)	Aves	VWA3A¹	von Willebrand factor A domain containing 3A	60.76(n) 55.86(a)		416616 XM_414917.3 XP_414917.3
lizard (Anolis carolinensis)	Reptilia	VWA3A⁶	von Willebrand factor A domain containing 3A	50(a)	1 ↔ 1	GL343846.1(113512-145914)
zebrafish (Danio rerio)	Actinopterygii	LOC100535802¹	von Willebrand factor A domain-containing protein 3A-like	49.61(n) 40.23(a)		100535802 XM_003198187.1 XP_003198235.1

ENSEMBL Gene Tree for VWA3A (if available)
TreeFam Gene Tree for VWA3A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for VWA3A gene

VWA3B²

1 SIMAP similar gene for VWA3A using alignment to 5 protein entries: VWA3A_HUMAN (see all proteins):

VWA3B

VWA3A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs184285417^1,2		--	22102308(+)	`GAAGCA/GAAGAA`	1	--	us2k¹		0	--	--	--	--
rs189186110^1,2		--	22102546(+)	`AATGCC/TGTGGT`	1	--	us2k¹		0	--	--	--	--
rs191614714^1,2		--	22102607(+)	`CTATTG/TTGAGC`	1	--	us2k¹		0	--	--	--	--
rs184888143^1,2		--	22102614(+)	`GAGCAC/TGTTGG`	1	--	us2k¹		0	--	--	--	--
rs189609648^1,2		--	22103060(+)	`ATTCTC/TAGAAA`	1	--	us2k¹		0	--	--	--	--
rs181535228^1,2		--	22103124(+)	`TTAGCA/GACTTA`	1	--	us2k¹		0	--	--	--	--
rs186847602^1,2		--	22103131(+)	`CTTACA/GAGTTG`	1	--	us2k¹		0	--	--	--	--
rs80135026^1,2	C,F	--	22103255(+)	`TTAAAA/CAGTCA`	1	--	us2k¹		1		WA	118
rs73533985^1,2	C,F	--	22103307(+)	`TGGGAA/TTGTTT`	1	--	us2k¹		2		WA	120
rs74012197^1,2	C,F	--	22103331(+)	`TCCAGG/ATGATT`	1	--	us2k¹		3		WA CSA	122

HapMap Linkage Disequilibrium report for VWA3A (22103859 - 22168287 bp)

Structural Variations
Database of Genomic Variants (DGV) 10/18 variations for VWA3A (see all 18): About this table

Variant ID	Type	Subtype	PubMed ID
esv2714075	CNV	Deletion	23290073
esv2714070	CNV	Deletion	23290073
esv2714073	CNV	Deletion	23290073
nsv435668	CNV	Deletion	17901297
dgv48n16	CNV	Insertion	17901297
nsv498860	CNV	Loss	21111241
nsv1764	CNV	Loss	18451855
dgv2647n71	CNV	Loss	21882294
nsv905598	CNV	Gain	21882294
nsv519813	CNV	Gain+Loss	19592680

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing VWA3A

DNA2.0 Custom Variant and Variant Library Synthesis for VWA3A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

VWA3A for disorders About MalaCards

VWA3A for disorders About GeneDecksing

Genetic Association Database (GAD): VWA3A

Export disorders for VWA3A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for VWA3A gene integrated from 9 sources:
(articles sorted by number of sources associating them with VWA3A)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)² Martin J.... Pennacchio L.A. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
The sequence of the human genome. (PubMed id 11181995)¹ Venter J.C.... Zhu X. (2001)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 146177	HGNC: 27088	AceView: LOC146177	Ensembl:ENSG00000175267	euGenes: HUgn146177
ECgene: VWA3A	H-InvDB: VWA3A

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for VWA3A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for VWA3A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for VWA3A gene:
Search GeneIP for patents involving VWA3A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for VWA3A
	Browse OriGene qPCR primer pairs and template standards		OriGene Protein Over-expression Lysate for VWA3A
	OriGene Custom Mass Spec		OriGene clones in human, mouse for VWA3A
	OriGene qSTAR qPCR primer pairs in human, mouse for VWA3A		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for VWA3A		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for VWA3A		OriGene Custom Protein Services for VWA3A

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VWA3A
	QIAGEN SeqTarget long-range PCR primers for resequencing VWA3A
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VWA3A
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VWA3A
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VWA3A
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VWA3A

	GenScript Custom Purified and Recombinant Proteins Services for VWA3A		GenScript cDNA clones with any tag delivered in your preferred vector for VWA3A
	GenScript Custom Assay Services for VWA3A		GenScript Custom Superior Antibodies Services for VWA3A
	GenScript Custom overexpressing Cell Line Services for VWA3A		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in VWA3A promoter
	Search Chromatin IP Primers for VWA3A
	RT² qPCR Primer Assay in human, mouse, rat VWA3A
	Search GNC Networks for VWA3A
	SABiosciences Custom PCR Arrays for VWA3A

Search Tocris compounds for VWA3A

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	VWA3A antibodies

	Search for Antibodies for VWA3A at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for VWA3A
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Search LifeMap BioReagents cell lines for VWA3A

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VWA3A

	Browse SwitchGear 3'UTR luciferase reporter plasmids for VWA3A
	Browse SwitchGear Promoter luciferase reporter plasmids for VWA3A

ThermoFisher Antibodies for VWA3A

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VWA3A

	inGenious Targeting Laboratory - Custom generated mouse model solutions for VWA3A
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for VWA3A

Customized:

	lentivirus for stable overexpression of VWA3A
	lentivirus expression plasmids for stable overexpression of VWA3A
	adenovirus for overexpression of VWA3A

Search LSBio for Antibodies for VWA3A

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes VWA3A gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

VWA3A Gene

Von Willebrand Factor A Domain Containing 3A

Aliases
for VWA3A gene

Summaries
for VWA3A gene

Genomic Views
for VWA3A gene

Proteins
for VWA3A gene

Protein Domains /
Families
for VWA3A gene

Function
for VWA3A gene

Pathways & Interactions
for VWA3A gene

Drugs & Compounds
for VWA3A gene

Transcripts
for VWA3A gene

Expression
for VWA3A gene

Orthologs
for VWA3A gene

Paralogs
for VWA3A gene

Genomic Variants
for VWA3A gene

Disorders / Diseases
for VWA3A gene

Publications
for VWA3A gene

External Searches for VWA3A gene

Genome Databases showing VWA3A gene

Other Databases showing VWA3A gene

Specialized Databases showing VWA3A gene

Intellectual Property
for VWA3A gene

Products
for VWA3A gene

View Random Gene

Advanced Search

Export list of displayed genes

VWA3A Gene

Von Willebrand Factor A Domain Containing 3A

Aliasesfor VWA3A gene

Summariesfor VWA3A gene

Genomic Viewsfor VWA3A gene

Proteinsfor VWA3A gene

Protein Domains /Familiesfor VWA3A gene

Functionfor VWA3A gene

Pathways & Interactionsfor VWA3A gene

Drugs & Compoundsfor VWA3A gene

Transcriptsfor VWA3A gene

Expression for VWA3A gene

Orthologsfor VWA3A gene

Paralogsfor VWA3A gene

Genomic Variantsfor VWA3A gene

Disorders / Diseasesfor VWA3A gene

Publicationsfor VWA3A gene

External Searches for VWA3A gene

Genome Databases showing VWA3A gene

Other Databases showing VWA3A gene

Specialized Databases showing VWA3A gene

Intellectual Propertyfor VWA3A gene

Productsfor VWA3A gene

View Random Gene

Aliases
for VWA3A gene

Summaries
for VWA3A gene

Genomic Views
for VWA3A gene

Proteins
for VWA3A gene

Protein Domains /
Families
for VWA3A gene

Function
for VWA3A gene

Pathways & Interactions
for VWA3A gene

Drugs & Compounds
for VWA3A gene

Transcripts
for VWA3A gene

Expression
for VWA3A gene

Orthologs
for VWA3A gene

Paralogs
for VWA3A gene

Genomic Variants
for VWA3A gene

Disorders / Diseases
for VWA3A gene

Publications
for VWA3A gene

Intellectual Property
for VWA3A gene

Products
for VWA3A gene