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Aliases for VTRNA1-2 Gene

Subcategory (RNA class) for VTRNA1-2 Gene

vault RNA

Quality Score for this RNA gene is


Aliases for VTRNA1-2 Gene

  • Vault RNA 1-2 2 3
  • Vault RNA Component 2 2 3
  • VAULTRC2 3 6
  • HVG2 3 6
  • Hvg-2 3
  • VR2 3

External Ids for VTRNA1-2 Gene

ORGUL Members for VTRNA1-2 Gene

Previous HGNC Symbols for VTRNA1-2 Gene


Previous GeneCards Identifiers for VTRNA1-2 Gene

  • GC05P140082
  • GC05P135243
  • GC05P140100
  • GC05P140102
  • GC05P140113

Summaries for VTRNA1-2 Gene

GeneCards Summary for VTRNA1-2 Gene

VTRNA1-2 (Vault RNA 1-2) is an RNA Gene, and is affiliated with the vault RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VTRNA1-2 Gene

Genomics for VTRNA1-2 Gene

Regulatory Elements for VTRNA1-2 Gene

Genomic Location for VTRNA1-2 Gene

140,718,925 bp from pter
140,719,013 bp from pter
89 bases
Plus strand

Genomic View for VTRNA1-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VTRNA1-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VTRNA1-2 Gene

Proteins for VTRNA1-2 Gene

Post-translational modifications for VTRNA1-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for VTRNA1-2 Gene

Domains for VTRNA1-2 Gene

Gene Families for VTRNA1-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with VTRNA1-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for VTRNA1-2 Gene

Function for VTRNA1-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for VTRNA1-2 Gene

Localization for VTRNA1-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for VTRNA1-2 Gene

Pathways for VTRNA1-2 Gene

SuperPathways for VTRNA1-2 Gene

No Data Available

Interacting Proteins for VTRNA1-2 Gene

Gene Ontology (GO) - Biological Process for VTRNA1-2 Gene


No data available for Pathways by source for VTRNA1-2 Gene

Transcripts for VTRNA1-2 Gene

mRNA/cDNA for VTRNA1-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for VTRNA1-2 Gene

No ASD Table

Relevant External Links for VTRNA1-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VTRNA1-2 Gene

mRNA expression in normal human tissues for VTRNA1-2 Gene

genes like me logo Genes that share expressions with VTRNA1-2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for VTRNA1-2 Gene

Orthologs for VTRNA1-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for VTRNA1-2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia Vault 36
  • 64 (a)
(Monodelphis domestica)
Mammalia Vault 36
  • 50 (a)
(Mus musculus)
Mammalia Vaultrc5 36
  • 43 (a)
(Pan troglodytes)
Mammalia Vault 36
  • 100 (a)
(Gallus gallus)
Aves Vault 36
  • 57 (a)
(Anolis carolinensis)
Reptilia Vault 36
  • 63 (a)
(Danio rerio)
Actinopterygii Vault 36
  • 49 (a)
Vault 36
  • 53 (a)
Vault 36
  • 52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea Vault 36
  • 49 (a)
Species with no ortholog for VTRNA1-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VTRNA1-2 Gene

Gene Tree for VTRNA1-2 (if available)
Gene Tree for VTRNA1-2 (if available)

Paralogs for VTRNA1-2 Gene

No data available for Paralogs for VTRNA1-2 Gene

Variants for VTRNA1-2 Gene

Sequence variations from dbSNP and Humsavar for VTRNA1-2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs2563296 -- 140,719,311(-) GGGCT(A/G)CAGGC downstream-variant-500B
rs2563297 -- 140,717,487(-) GCTGC(A/G)GTAAT upstream-variant-2KB
rs12188417 -- 140,719,011(+) GCTCT(G/T)TTACT nc-transcript-variant
rs35373660 -- 140,718,281(+) AATAA(-/T)ATAAA upstream-variant-2KB
rs35623644 -- 140,718,285(+) AATAA(-/T)ATGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for VTRNA1-2 Gene

Variant ID Type Subtype PubMed ID
nsv830508 CNV Loss 17160897
nsv882950 CNV Loss 21882294
esv2730832 CNV Deletion 23290073
esv2661261 CNV Deletion 23128226
esv23837 CNV Loss 19812545
esv2730833 CNV Deletion 23290073

Relevant External Links for VTRNA1-2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VTRNA1-2 Gene

Disorders for VTRNA1-2 Gene

No disorders were found for VTRNA1-2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for VTRNA1-2 Gene

Publications for VTRNA1-2 Gene

  1. Vaults are up-regulated in multidrug-resistant cancer cell lines. (PMID: 9535882) Kickhoefer V.A. … Rome L.H. (J. Biol. Chem. 1998) 2 3
  2. Epstein-barr virus-induced expression of a novel human vault RNA. (PMID: 19298825) Nandy C. … Polacek N. (J. Mol. Biol. 2009) 2 3
  3. Evolution of vault RNAs. (PMID: 19491402) Stadler P.F. … Ullmann K. (Mol. Biol. Evol. 2009) 2 3
  4. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz H.J. … Yaspo M.L. (J. Biol. Chem. 2011) 3
  5. Vaults and telomerase share a common subunit, TEP1. (PMID: 10551828) Kickhoefer V.A. … Rome L.H. (J. Biol. Chem. 1999) 3

Products for VTRNA1-2 Gene

Sources for VTRNA1-2 Gene

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