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Aliases for VTRNA1-2 Gene

Subcategory (RNA class) for VTRNA1-2 Gene

vault RNA

Quality Score for this RNA gene is

3

Aliases for VTRNA1-2 Gene

  • Vault RNA 1-2 2 3 5
  • Vault RNA Component 2 2 3
  • VAULTRC2 3
  • Hvg-2 3
  • HVG2 3
  • VR2 3

External Ids for VTRNA1-2 Gene

ORGUL Members for VTRNA1-2 Gene

Previous HGNC Symbols for VTRNA1-2 Gene

  • VAULTRC2

Previous GeneCards Identifiers for VTRNA1-2 Gene

  • GC05P140082
  • GC05P135243
  • GC05P140100
  • GC05P140102
  • GC05P140113
  • GC05P141428
  • GC05P141566
  • GC05P141668
  • GC05P141769
  • GC05P141869

Summaries for VTRNA1-2 Gene

GeneCards Summary for VTRNA1-2 Gene

VTRNA1-2 (Vault RNA 1-2) is an RNA Gene, and is affiliated with the vault RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VTRNA1-2 Gene

Genomics for VTRNA1-2 Gene

Regulatory Elements for VTRNA1-2 Gene

Enhancers for VTRNA1-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G140717 1.2 ENCODE 0.7 +0.2 212 2.7 MLX CREB3L1 ZNF416 ZNF263 SP3 PPARGC1A MEF2D GLIS1 RCOR2 NBN HDAC3 TMCO6 PURA LOC102723915 PCDHA3 IGIP PCDHB3 PCDHB9 PCDHB7 PCDHB15
GH05G140725 1.1 ENCODE 0.4 +7.1 7058 1.1 PKNOX1 ARNT ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 FOS KLF13 HDAC3 LOC102723915 PCDHA4 TMCO6 FCHSD1 HARS LOC101929719 PCDHA3 GC05P141999 VTRNA1-3
GH05G140712 0.6 Ensembl 0.4 -6.8 -6825 0.2 SMARCA5 RBAK ZNF512 ZNF133 ADNP ZNF624 ZEB1 LOC105378198 GC05P142003 VTRNA1-2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around VTRNA1-2 on UCSC Golden Path with GeneCards custom track

Promoters for VTRNA1-2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000187821 -325 401 PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A ZNF2 ZNF766 CBX5

Genomic Location for VTRNA1-2 Gene

Chromosome:
5
Start:
140,718,925 bp from pter
End:
140,719,013 bp from pter
Size:
89 bases
Orientation:
Plus strand

Genomic View for VTRNA1-2 Gene

Genes around VTRNA1-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
VTRNA1-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for VTRNA1-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VTRNA1-2 Gene

Proteins for VTRNA1-2 Gene

Post-translational modifications for VTRNA1-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for VTRNA1-2 Gene

Domains & Families for VTRNA1-2 Gene

Gene Families for VTRNA1-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with VTRNA1-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for VTRNA1-2 Gene

Function for VTRNA1-2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for VTRNA1-2 Gene

Localization for VTRNA1-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for VTRNA1-2 Gene

Pathways & Interactions for VTRNA1-2 Gene

SuperPathways for VTRNA1-2 Gene

No Data Available

Interacting Proteins for VTRNA1-2 Gene

Gene Ontology (GO) - Biological Process for VTRNA1-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for VTRNA1-2 Gene

Drugs & Compounds for VTRNA1-2 Gene

No Compound Related Data Available

Transcripts for VTRNA1-2 Gene

mRNA/cDNA for VTRNA1-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for VTRNA1-2 Gene

No ASD Table

Relevant External Links for VTRNA1-2 Gene

GeneLoc Exon Structure for
VTRNA1-2
ECgene alternative splicing isoforms for
VTRNA1-2

Expression for VTRNA1-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for VTRNA1-2 Gene

genes like me logo Genes that share expression patterns with VTRNA1-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for VTRNA1-2 Gene

Orthologs for VTRNA1-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for VTRNA1-2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia Vault 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia Vault 35
  • 64 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia Vault 35
  • 50 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Vaultrc5 35
  • 43 (a)
OneToMany
chicken
(Gallus gallus)
Aves Vault 35
  • 57 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia Vault 35
  • 63 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii Vault 35 35 35
  • 49 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea Vault 35
  • 49 (a)
OneToMany
Species where no ortholog for VTRNA1-2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VTRNA1-2 Gene

ENSEMBL:
Gene Tree for VTRNA1-2 (if available)
TreeFam:
Gene Tree for VTRNA1-2 (if available)

Paralogs for VTRNA1-2 Gene

No data available for Paralogs for VTRNA1-2 Gene

Variants for VTRNA1-2 Gene

Sequence variations from dbSNP and Humsavar for VTRNA1-2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1003663323 -- 140,717,608(+) TGCTG(G/T)TAAGT intron-variant, upstream-variant-2KB
rs1004069545 -- 140,719,438(+) ATCAC(-/AAAAAAAAA)AAAAA intron-variant, downstream-variant-500B
rs1004184283 -- 140,719,015(+) TTTTA(C/T)TGCTG intron-variant, downstream-variant-500B
rs1008523832 -- 140,717,980(+) GGGCC(A/C)GATGG intron-variant, upstream-variant-2KB
rs1010909034 -- 140,717,199(+) AGGAA(G/T)ATCCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for VTRNA1-2 Gene

Variant ID Type Subtype PubMed ID
esv23837 CNV loss 19812545
esv2661261 CNV deletion 23128226
esv2730832 CNV deletion 23290073
esv2730833 CNV deletion 23290073
esv3566720 CNV deletion 23714750
esv3570456 CNV loss 25503493
esv3606954 CNV loss 21293372
nsv1074334 CNV deletion 25765185
nsv599826 CNV loss 21841781
nsv830508 CNV loss 17160897

Relevant External Links for VTRNA1-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
VTRNA1-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for VTRNA1-2 Gene

Disorders for VTRNA1-2 Gene

Relevant External Links for VTRNA1-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
VTRNA1-2

No disorders were found for VTRNA1-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for VTRNA1-2 Gene

Publications for VTRNA1-2 Gene

  1. Epstein-barr virus-induced expression of a novel human vault RNA. (PMID: 19298825) Nandy C. … Polacek N. (J. Mol. Biol. 2009) 2 3 64
  2. Evolution of vault RNAs. (PMID: 19491402) Stadler P.F. … Ullmann K. (Mol. Biol. Evol. 2009) 2 3 64
  3. Vaults are up-regulated in multidrug-resistant cancer cell lines. (PMID: 9535882) Kickhoefer V.A. … Rome L.H. (J. Biol. Chem. 1998) 2 3 64
  4. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz H.J. … Yaspo M.L. (J. Biol. Chem. 2011) 3 64
  5. Vaults and telomerase share a common subunit, TEP1. (PMID: 10551828) Kickhoefer V.A. … Rome L.H. (J. Biol. Chem. 1999) 3 64

Products for VTRNA1-2 Gene

Sources for VTRNA1-2 Gene

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