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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VTI1B Gene

protein-coding   GIFtS: 59
GCID: GC14M068117

vesicle transport through interaction with t-SNAREs 1B

(Previous name: vesicle transport through interaction with t-SNAREs homolog...)
 Explore 5 diseases affiliated with
VTI1B via our new
 Human Malady Compendium 
Biological research products
for VTI1B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Vesicle Transport Through Interaction With T-SNAREs 1B1 2     V-SNARE1
VTI21 2 3     Vesicle Transport Through Interaction With T-SNAREs Homolog 1B2
Vesicle Transport V-SNARE Protein Vti1-Like 12 3     Vesicle-Associated Soluble NSF Attachment Protein Receptor2
VTI12 3     Vti1-Rp11
VTI1L2 3     VTI1L13
Vesicle Transport Through Interaction With T-SNAREs Homolog 1B (Yeast)1     Vti1-Rp11
VTI1-LIKE2     

External Ids:    HGNC: 177931   Entrez Gene: 104902   Ensembl: ENSG000001005687   OMIM: 6032075   UniProtKB: Q9UEU03   

Export aliases for VTI1B gene to outside databases

Previous GC identifers: GC14M061911 GC14M066103 GC14M066107 GC14M067187 GC14M048287


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: VTI1B_HUMAN, Q9UEU0
Function: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane.
These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of
the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence

Gene Wiki entry for VTI1B


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VTI1B gene promoter:
         TBP   ER-alpha   p53   MEF-2   MyoD   Arnt   AREB6   MEF-2A   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVTI1B promoter sequence
   Search SABiosciences Chromatin IP Primers for VTI1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VTI1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.1   Ensembl cytogenetic band:  14q24.1   HGNC cytogenetic band: 14q23.3

VTI1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VTI1B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M068117:  view genomic region     (about GC identifiers)

Start:
68,113,792 bp from pter      End:
68,141,602 bp from pter
Size:
27,811 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VTI1B_HUMAN, Q9UEU0 (See protein sequence)
Recommended Name: Vesicle transport through interaction with t-SNAREs homolog 1B  
Size: 232 amino acids; 26688 Da
Subunit: Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which
functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8
(By similarity)
Subcellular location: Endomembrane system; Single-pass type IV membrane protein. Cytoplasmic granule
1 PDB 3D structure from and Proteopedia for VTI1B:
2V8S (3D)    
Secondary accessions: O43547 Q96J28
Alternative splicing: 2 isoforms:  Q9UEU0-1   Q9UEU0-2   

Explore the universe of human proteins at neXtProt for VTI1B: NX_Q9UEU0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UEU0

  • VTI1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006361.1  
    ENSEMBL proteins: 
     ENSP00000450731   ENSP00000451661   ENSP00000451759   ENSP00000216456   ENSP00000452366  

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    Uscn Proteins for VTI1B

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IDA19224922
    GO:0012505endomembrane system IEA--
    GO:0016021integral to membrane IEA--
    GO:0031201SNARE complex ----


    VTI1B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    VTI1B for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000727 T_SNARE_dom
     IPR010989 t-SNARE
     IPR007705 Vesicle_trsprt_v-SNARE_N

    Graphical View of Domain Structure for InterPro Entry Q9UEU0

    ProtoNet protein and cluster: Q9UEU0

    1 Blocks protein family: IPB007705 Vesicle transport v-SNARE

    UniProtKB/Swiss-Prot: VTI1B_HUMAN, Q9UEU0
    Similarity: Belongs to the VTI1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: VTI1B_HUMAN, Q9UEU0
    Function: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane.
    These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of
    the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence

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    SwitchGear 3'UTR luciferase reporter plasmidVTI1B 3' UTR sequence
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    VTI1B for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Vti1btm1Gfvm for VTI1B
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Vti1b):
     cellular  endocrine/exocrine gland  growth/size  liver/biliary system  mortality/aging 
     nervous system  vision/eye 

    VTI1B for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin-dependent protein traffic
    Transport_Clathrin-coated vesicle cycle0.66
    wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)0.37
    2wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)
    wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)1.00
    3Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    SNARE interactions in vesicular transport0.40

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3 GeneGo (Thomson Reuters) Pathways for VTI1B
        wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
    Transport Clathrin-coated vesicle cycle
    wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)


    1         Kegg Pathway  (Kegg details for VTI1B):
        SNARE interactions in vesicular transport


    VTI1B for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VTI1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    5/23 Interacting proteins for VTI1B (Q9UEU02, 3 ENSP000002164564) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STX8Q9UNK02, 3, ENSP000003052554MINT-66165 I2D: score=7 STRING: ENSP00000305255
    GOLGB1Q147892, 3, ENSP000003418484MINT-64183 I2D: score=4 STRING: ENSP00000341848
    TNK2Q079122, 3MINT-64709 I2D: score=3 
    NSFP464593, ENSP000003812934I2D: score=3 STRING: ENSP00000381293
    STX7O154003, ENSP000003569184I2D: score=3 STRING: ENSP00000356918
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IEA--
    GO:0006904vesicle docking involved in exocytosis TAS9446565
    GO:0006944cellular membrane fusion TAS9446565
    GO:0008283cell proliferation TAS9446565
    GO:0016192vesicle-mediated transport TAS9446565


    VTI1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    VTI1B for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VTI1B
    10 Novoseek chemical compound relationships for VTI1B gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lm-a1 87.5 1 9657146 (1)
    vti 1 84.5 1 9446565 (1)
    n-ethylmaleimide 61.6 5 11066058 (1), 15037235 (1), 12244131 (1), 11781091 (1)
    calcium 33.3 11 19195551 (2), 17204559 (1), 16390104 (1), 19195550 (1) (see all 5)
    atp 28.4 2 11423412 (1), 15608145 (1)
    phospholipid 18.7 2 19195551 (1)
    lipid 13.9 7 11463334 (1), 19195551 (1), 16390104 (1), 19195550 (1)
    cysteine 12.7 2 17081110 (1), 14567912 (1)
    gtp 8.19 1 9657146 (1)
    glucose 2.91 1 10713150 (1)

    Search CenterWatch for drugs/clinical trials and news about VTI1B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for VTI1B gene: 
    NM_006370.2  

    Unigene Cluster for VTI1B:

    Vesicle transport through interaction with t-SNAREs 1B
    Hs.741177  [show with all ESTs]
    Unigene Representative Sequence: BC042390
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554659(uc001xjt.3 uc010aqp.3 uc001xju.3) ENST00000554636
    ENST00000556461 ENST00000216456 ENST00000553619 ENST00000555543

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    Additional cDNA sequence: 

    AF035824.1 AF060902.1 AK291689.1 AK310839.1 AK316572.1 BC003142.1 BC042390.1 BT019348.1 
    BT019960.1 CR456757.1 CR542095.1 

    16 DOTS entries:

    DT.80100028  DT.99995824  DT.318788  DT.91936909  DT.100798309  DT.120767834  DT.100798313  DT.120767794 
    DT.422252  DT.70100345  DT.100798312  DT.101983989  DT.120767762  DT.92046439  DT.95170339  DT.86845723 

    24/1100 AceView cDNA sequences (see all 1100):

    AA054437 AI753763 BU541331 BQ936653 CR602441 BC051291 AI659880 CB160058 
    AV651937 BE513333 CB151074 BM679606 BE407156 AJ715084 BE294361 BX360732 
    BQ685542 BE222992 BP336826 BM547083 AL135371 BM562255 BQ648240 AF395068 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for VTI1B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6
    SP1:                    -                                 
    SP2:              -     -                                 
    SP3:                                                      


    ECgene alternative splicing isoforms for VTI1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VTI1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATGTTAGGGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See VTI1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VTI1B

    SOURCE GeneReport for Unigene cluster: Hs.741177

    UniProtKB/Swiss-Prot: VTI1B_HUMAN, Q9UEU0
    Tissue specificity: Expressed in all tissues examined

        SABiosciences Custom PCR Arrays for VTI1B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VTI1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for VTI1B gene from 4/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves VTI1B1 vesicle transport through interaction with t-SNAREs more 72.59(n)
    78.22(a)
      423273  XM_421192.3  XP_421192.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    71(a)
    69(a)
    1 ↔ many
    1 ↔ many
    GL343272.1(1006371-1024225)
    GL343444.1(119612-121172)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.120132 Transcribed sequence with weak similarity to protein more 71.77(n)    BX732625.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc635252 similar to vesicle transport through interaction with more 73.28(n)   394011  BC055131.1 


    ENSEMBL Gene Tree for VTI1B (if available)
    TreeFam Gene Tree for VTI1B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for VTI1B gene
    VTI1A2  
    1 SIMAP similar gene for VTI1B using alignment to 5 protein entries:     VTI1B_HUMAN (see all proteins):
    VTI1A

    VTI1B for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for VTI1B
    PGOHUM00000239791 PGOHUM00000238116 PGOHUM00000246153 PGOHUM00000236776


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/449 NCBI SNPs in VTI1B are shown (see all 449    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1910226151,2
    --68119085(+) TGAAGA/TCAATC 1 -- int10--------
    rs171045471,2
    C,F,H,--68119093(+) ATCCCA/GTTTCT 1 -- int19Minor allele frequency- G:0.07NA NS EA CSA WA 682
    rs1823650691,2
    --68119099(+) TTTCTC/TGGGAA 1 -- int10--------
    rs171045501,2
    C,F,--68119120(+) AGCCAG/ACTGAT 1 -- int16Minor allele frequency- A:0.11NA WA EA 500
    rs1163126411,2
    F,--68119219(+) TTCCAT/CTCTTC 1 -- int11Minor allele frequency- C:0.08WA 118
    rs1874317591,2
    --68119294(+) GGTCCC/TCTGGG 1 -- int10--------
    rs1116977591,2
    C,--68119534(+) GAGACG/AGAGTC 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1495392821,2
    --68119541(+) AGTCTC/TGCTTT 1 -- int10--------
    rs1112696781,2
    --68119577(+) GCCATC/TTCGGC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1908984091,2
    --68119584(+) CGGCTC/TACTGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for VTI1B (68113792 - 68141602 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for VTI1B: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    VTI1B for disorders           About GeneDecksing

    OMIM gene information: 603207    OMIM disorders: --

    5 diseases for VTI1B:    About MalaCards
    insulin resistance    tetanus    cholesterol    melanoma
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for VTI1B:
    Hemophagocytic lymphohistiocytosis

    2 Novoseek disease relationships for VTI1B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tetanus 35.8 2 17567262 (1), 14973236 (1)
    insulin resistance 4.9 1 17848561 (1)

    Human Genome Epidemiology (HuGE) Navigator: VTI1B (1 document)

    Export disorders for VTI1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VTI1B gene, integrated from 9 sources (see all 103):
    (articles sorted by number of sources associating them with VTI1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways. (PubMed id 9446565)1, 2, 3, 9 Fischer von Mollard G. and Stevens T.H. (1998)
    2. A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts. (PubMed id 9636656)1, 2, 3 Li H.-C.... Ide T. (1998)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Combinational soluble N-ethylmaleimide-sensitive fact or attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antim icrobial and canonical autophagosomes with lysosomes. (PubMed id 20089838)1, 9 Furuta N....Amano A. (2010)
    5. Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells. (PubMed id 18570918)1, 9 Bilan F....Thoreau V. (2008)
    6. Defective HIV-1 particle assembly in AP-3-deficient ce lls derived from patients with Hermansky-Pudlak syndrome type 2. (PubMed id 22875976)1 Liu L....Dong X. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. ErbB2-associated changes in the lysosomal proteome. (PubMed id 21674799)1 Nylandsted J....Jaattela M. (2011)
    10. Docking of lytic granules at the immunological synaps e in human CTL requires Vti1b-dependent pairing with CD3 endosomes. (PubMed id 21562157)1 Qu B....Hoth M. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10490 HGNC: 17793 AceView: VTI1B Ensembl:ENSG00000100568 euGenes: HUgn10490
    ECgene: VTI1B Kegg: 10490 H-InvDB: VTI1B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VTI1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VTI1B gene:
    Search GeneIP for patents involving VTI1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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