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VTCN1 Gene

protein-coding   GIFtS: 51

GC01M117686
V-set domain containing T cell activation inhibitor 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
V-set domain containing T cell activation inhibitor 11 2     T-cell costimulatory molecule B7x2 3
B7H41 2 3     T cell costimulatory molecule B7x2
FLJ224181 2     PRO12912
B7-H41 2     V-set domain-containing T-cell activation inhibitor 12
B7X1 2     VCTN12
B7S11 2     RP11-229A19.42
Immune costimulatory protein B7-H42 3     Protein B7S13
B7h.52 3     

External Ids:    HGNC: 288731   Entrez Gene: 796792   Ensembl: ENSG000001342587   UniProtKB: Q7Z7D33   

Search outside databases for aliases for VTCN1 gene

Previous GC identifer: GC01M117399

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VTCN1:
B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the
surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes.(supplied by
OMIM)

UniProtKB/Swiss-Prot: VTCN1_HUMAN, Q7Z7D3
Function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine
production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an
important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific
T-cell immunity. Involved in promoting epithelial cell transformation

Gene Wiki entry for VTCN1
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
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Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the VTCN1 gene upstream (promoter) region "":
C/EBPalpha   CHOP-10   NF-kappaB1   NF-kappaB   NF-kappaB2   Tal-1beta   ITF-2   c-Rel   NRSF form 1   NRSF form 2   

Epigenetics:
"" Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for VTCN1 ""

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.1   Ensembl cytogenetic band:  1p13.1   HGNC cytogenetic band: 1p12

VTCN1 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M117686:  view genomic region     (about GC identifiers)

Start:
117,686,209 bp from pter
End:
117,753,556 bp from pter
Size:
67,348 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: VTCN1_HUMAN, Q7Z7D3 (See protein sequence)
Recommended Name: V-set domain-containing T-cell activation inhibitor 1 precursor  
Size: 282 amino acids; 30878 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein (Potential). Note=Expressed at the cell
surface. A soluble form has also been detected
Miscellaneous: May serve as a predictive marker for renal cell carcinoma
Caution: The mouse ortholog has been shown (PubMed:12818166) to be a GPI-anchored protein but the Gly residue which is
predicted to be the modified site in mouse and rat is not conserved in human
Secondary accessions: Q0GN76 Q45VN0 Q5WPZ3 Q9H6B2
Alternative splicing: 3 isoforms:  Q7Z7D3-1   Q7Z7D3-2   Q7Z7D3-3   

Post-translational modifications:

  • N-glycosylated1


  • REFSEQ proteins: NP_078902.2  

    ENSEMBL proteins: 
    ENSP00000358470 ENSP00000351899 ENSP00000328168 ENSP00000358468 


    Human Recombinant Proteins 
    ""Browse Purified and Recombinant Proteins at Millipore
    ""Browse Human Recombinant Proteins at Sigma-Aldrich
    "" Browse R&D Systems for human recombinant proteins
    ""Browse recombinant and purified proteins available from Enzo Life Sciences
    ""Browse Abnova for HuPro® and/or Recombinant Proteins
    ""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
    Novus Biologicals Lysate for VTCN1
    ""Browse Sino Biological Recombinant Proteins  ""

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886 plasma membrane IEA--
    GO:0016021 integral to membrane IEA--
    About this table

    "" VTCN1 for ontologies           About GeneDecksing



    Antibodies for VTCN1: 
    ""Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    ""Sigma-Aldrich Antibodies for VTCN1
    ""R&D Systems Antibodies for VTCN1 (B7-H4)
    ""Monoclonal and Polyclonal Antibodies from Abnova (VTCN1)
    "" Origene Antibodies: VTCN1 ""
    ""Novus Biologicals Antibodies for VTCN1
    ""Epitomics antibodies for VTCN1

    Assays for VTCN1: 
    ""Browse Kits and Assays available from Millipore
    ""Browse ELISAs at Sigma-Aldrich
    "" Browse R&D Systems for biochemical assays
    ""Browse Enzo Life Sciences for kits & assays

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    "" VTCN1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q7Z7D3

    ProtoNet protein and cluster: Q7Z7D3

    1 Blocks protein family: IPB013106 Immunoglobulin V-set

    UniProtKB/Swiss-Prot: VTCN1_HUMAN, Q7Z7D3
    Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family
    Similarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains

    (According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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    Inhib.
    RNA:
    ""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    "" Origene 29mer shRNA kits in GFP-retroviral vector: VTCN1
    Origene shRNA RFP: VTCN1
    Origene basic RS shRNA: VTCN1

    ""Applied Biosystems Silencer® siRNAs for VTCN1
    ""Sigma-Aldrich siRNA for VTCN1
    Sigma-Aldrich shRNA Panels and shRNA for VTCN1
    Explore Sigma-Aldrich super-pooled esiRNAs
    Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    ""Browse iPSC Reprogramming Factors at Sigma-Aldrich
    "" Origene GFP tagged cDNA clones in CMV expression vector: VTCN1
    Origene Myc/DDK tagged cDNA clones in CMV expression vector: VTCN1
    Origene untagged cDNA clones in CMV expression vector: VTCN1
    ""Sino Biological Human cDNA Clone for VTCN1  ""

    UniProtKB/Swiss-Prot: VTCN1_HUMAN, Q7Z7D3
    Function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine
    production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an
    important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific
    T-cell immunity. Involved in promoting epithelial cell transformation
    Induction: Up-regulated by IL-6 and IL-10 and inhibited by GM-CSF and IL-4 on antigen-presenting cells (APCs)

    1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102 receptor binding ----
    About this table

    "" VTCN1 for ontologies           About GeneDecksing

    Animal Models: 4 MGI mutant phenotypes (inferred from 4 alleles""(MGI details for Vtcn1):

    hematopoietic systemimmune systemlife span-post-weaning/agingnormal

    "" VTCN1 for phenotypes           About GeneDecksing

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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    "" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VTCN1

    2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955 immune response IEA--
    GO:0050868 negative regulation of T cell activation ----
    About this table

    "" VTCN1 for ontologies           About GeneDecksing


    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

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    "" VTCN1 for compounds           About GeneDecksing

    "" Browse drugs & compounds from Enzo Life Sciences
    ""Browse Small Molecules at Sigma-Aldrich

    "" Browse Tocris compounds for VTCN1
    4 ""Novoseek chemical compound relationships for VTCN1 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    indoleamine 1.94 1 19880363 (1)
    creatinine 0.41 1 17051145 (1)
    progesterone 0.27 1 15756008 (1)
    nitric oxide 0.09 1 16606666 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
    Expression Assays from Applied Biosystems)
    About This Section

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    Inhib.
    RNA:
    ""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    ""Applied Biosystems Silencer® siRNAs:  NM_024626  
    "" Origene 29mer shRNA kits in GFP-retroviral vector: VTCN1
    Origene shRNA RFP: VTCN1
    Origene basic RS shRNA: VTCN1

    ""Sigma-Aldrich siRNA for VTCN1
    Sigma-Aldrich shRNA Panels and shRNA for VTCN1
    Explore Sigma-Aldrich super-pooled esiRNAs

    microRNA:""9 SABiosciences microRNAs that regulate VTCN1""
    hsa-miR-125a-5p hsa-miR-15a hsa-miR-503 hsa-miR-497 hsa-miR-424 hsa-miR-125b hsa-miR-16 hsa-miR-195 hsa-miR-15b
    Assays:  ""Applied Biosystems TaqMan® Gene Expression Assays:  
    NM_024626  


    Clones:"" Origene GFP tagged cDNA clones in CMV expression vector: VTCN1
    Origene Myc/DDK tagged cDNA clones in CMV expression vector: VTCN1
    Origene untagged cDNA clones in CMV expression vector: VTCN1
    Primers:"" Origene genome-wide validated SYBR primer pairs: VTCN1
    ""SABiosciences RT2 qPCR Primer Assay for VTCN1: PPH09043A ""

    REFSEQ mRNAs for VTCN1 gene: 

    NM_024626.2  

    Additional cDNA sequence: 

    AK225413.1 AK303466.1 AK310812.1 AY280972.1 AY346100.1 AY358352.1 AY442303.1 BC065717.1 
    BC074729.2 BX648021.1 CR603772.1 DQ103757.1 DQ836392.1 

    3 DOTS entries:

    DT.100697933  DT.92070437  DT.312331 

    24/70 AceView cDNA sequences (see all 70 ):

    AY280972 AK026071 BM981657 CA311913 CR603772 AI682137 AI539195 CB852239 
    AI686571 AA404609 AI683712 NM_024626 CB241729 AI684143 AA291512 AI638559 
    AA171844 AI858190 BC074729 AW470108 BU680630 BE741325 BX499180 AI539668 

    "" highest scoring ESTs for VTCN1:

    AA333549 AI799522 AY280972 BC065717 BF680206 BX499180 BX648021 AA075579 AA075632 AA171844 

    Unigene Cluster for VTCN1:

    V-set domain containing T cell activation inhibitor 1
    Hs.546434  [show with all ESTs]
    Unigene Representative Sequence: BX648021


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for VTCN1

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c
    SP1:              -                                                         
    SP2:              -           -                                             
    SP3:                          -                                             
    SP4:              -           -     -                                       

    About this scheme

    ECgene alternative splicing isoforms for VTCN1

    6 Ensembl transcripts including schematic representations:
    ENST00000488493  ENST00000369458  ENST00000359008  ENST00000463461  ENST00000328189  ENST00000369456  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
    About This Section

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    VTCN1 expression in normal and diseased human tissues

    "" Applied Biosystems TaqMan ® Gene Expression Assays for VTCN1

    1""  / 2""  / 3""

    4 probe-sets matching VTCN1 gene

    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    45137_at2, 3 U95-B 1 1.00 1.00 0.99 0.77 AA075632 0.60 1.00 0.82 1
    72384_at2, 3 U95-D 2 1.00 0.91 0.94 1.28 AI799522 0.80 1.00 0.91 1
    219768_at2, 3 U133-A 1 1.00 1.00 -- -- NM_024626 0.40 1.00 0.76 1
    219768_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    "" VTCN1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TTGTTATAGA

    SOURCE GeneReport for Unigene cluster: Hs.546434

    UniProtKB/Swiss-Prot: VTCN1_HUMAN, Q7Z7D3
    Tissue specificity: Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers
    (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal
    tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis

    Primers:"" Origene genome-wide validated SYBR primer pairs: VTCN1 ""
    ""SABiosciences RT2 qPCR Primer Assay for VTCN1: PPH09043A ""
    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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    Orthologs for VTCN1 gene from 5/6 species (see all 6 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    VTCN11   -- V-set domain containing T cell activation inhibitor more 91.39(n)
    94.46(a)
    483140  XM_540258.2  XP_540258.2 
    chimpanzee
    (Pan troglodytes)
    VTCN11   -- V-set domain containing T cell activation inhibitor more 99.51(n)
    99.26(a)
    469433  XM_524817.2  XP_524817.2 
    cow
    (Bos taurus)
    VTCN11   -- V-set domain containing T cell activation inhibitor more 89.91(n)
    91.14(a)
    539919  XM_590312.3  XP_590312.2 
    rat
    (Rattus norvegicus)
    Vtcn11   -- V-set domain containing T cell activation inhibitor more 84.4(n)
    86.88(a)
    295322  NM_001024244.1  NP_001019415.1 
    mouse
    (Mus musculus)
    Vtcn11, 5 35
    V-set domain containing T cell activation inhibitor more1, 5 84.87(n)1
    87.59(a)1
    2421221  NM_178594.21  NP_848709.11 
     AK1432765  AK1456645  (see all 10)
    About this table        Species with no ortholog for VTCN1

    ENSEMBL Gene Tree for VTCN1
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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    Paralogs for VTCN1 gene
    HHLA22  

    "" VTCN1 for paralogs           About GeneDecksing


    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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    10/109 NCBI SNPs in VTCN1 are shown (see all 109 )
    (Click "" for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 144)
    ABGenomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 1 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    --
    rs19379561,2
    C,F,O,A,H117687125(-) CCTTGT/ACTATA 1 -- ut31""110Minor allele frequency- A:0.46NS EA NA PA EU CA WA 6998""
    --
    rs135051,2
    C,F,A,H117686492(-) ACCCTT/GCCTGG 1 -- ut31 ese3""6Minor allele frequency- G:0.22MN NA 380""
    ""
    rs14186681,2
    C,F,A,H115612801(-) AGCACC/TGGCAC 1 -- ng51""9Minor allele frequency- T:0.02NS EA NA WA 476""
    --
    rs66647591,2
    C,F,A,H117686914(+) GGCCTT/CTATCC 1 -- ut31 ese3""6Minor allele frequency- C:0.15NA EA WA 146""
    --
    rs64286791,2
    C,F,A,H117686827(+) cttagT/Ccctga 1 -- ut31 ese3""5Minor allele frequency- C:0.29NA 80""
    --
    rs66738371,2
    C,F,H115544042(+) TGCCAG/AGCTGG 1 -- ng31""18Minor allele frequency- A:0.09NS EA NA 1338""
    ""
    rs14186701,2
    C,F,H115612559(-) TTCTCC/TCTGCT 1 -- ng51""8Minor allele frequency- T:0.02NS EA WA NA 472""
    ""
    rs38063741,2
    C,F,A115612243(+) AATACC/TCAGAA 1 -- ng51 tfbs3""11Minor allele frequency- T:0.26NS EA NA WA 634""
    ""
    rs75402861,2
    C,F,A115613395(+) acaggC/Aaaaca 1 -- ng51 tfbs3""9Minor allele frequency- A:0.23NS EA WA NA 558""
    ""
    rs14186691,2
    C,H115612714(-) TCACTC/GCAACC 1 -- ng51""9Minor allele frequency- G:0.01NS EA NA WA 446""
    About this table

    HapMap Linkage Disequilibrium images for VTCN1 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
          Database of Genomic Variants (DGV) variations for VTCN1: --

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

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    "" VTCN1 for disorders           About GeneDecksing

    OMIM: 608162

    10/21 ""Novoseek disease relationships for VTCN1 gene (see all 21 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    ovarian cancer 18.88 15 15878339 (4), 17875732 (3), 16606666 (3), 16452214 (3) (see all 5)
    ovarian cancer stage 5.49 2 17498784 (2)
    ovarian tumor 4.46 3 16606666 (2), 17875732 (1)
    papillary serous carcinoma 4.24 2 16725184 (2)
    breast cancer 3.58 8 15756008 (4), 15878339 (3), 16452214 (1)
    benign ovarian tumor 2.30 1 17498784 (1)
    invasive lobular carcinoma 2.10 1 15756008 (1)
    tumor immunity 2.07 1 16606666 (1)
    gynecologic disease 1.96 1 16452214 (1)
    invasive ductal carcinoma 1.52 1 15756008 (1)
    About this table

    Human Genome Epidemiology Navigator: VTCN1 (2 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

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      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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    10/32 PubMed articles for VTCN1 gene (see all 32 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

      User Feedback
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79679 HGNC: 28873 AceView: B7-H4 Ensembl:ENSG00000134258 euGenes: HUgn79679
    ECgene: VTCN1 H-InvDB: VTCN1
    (According to HUGE)
    About This Section

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      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

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      --
    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section

      User Feedback
    Patent Information for VTCN1 gene: ""
    Search GeneIP for patents involving VTCN1

    GeneCards and IP: ""
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
    Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
    Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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    ""
    ""
    Products for VTCN1:
    "" TaqMan ® Gene Expression Assays
    "" TaqMan ® Genotyping Assays
     "" Free SNP selection tool

    ""
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    "" Millipore Preclinical / Clinical Development Services
    "" Millipore Immunoassay Services
    "" Millipore Target Screening & Profiling Services

    ""
    "" Predesigned and custom siRNAs for VTCN1"" Antibodies for VTCN1
    "" Explore super-pooled esiRNAs"" Browse proteins at Sigma-Aldrich
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    GeneCards Homepage - Last full update: 21 May 2010 - Incremental updates: 24 May 2010 , 20 Jun 2010

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    acyl-CoA synthetase family member 3
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