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Aliases for VSTM5 Gene

Aliases for VSTM5 Gene

  • V-Set And Transmembrane Domain Containing 5 2 3 5
  • C11orf90 3 4
  • V-Set And Transmembrane Domain-Containing Protein 5 3
  • Chromosome 11 Open Reading Frame 90 2

External Ids for VSTM5 Gene

Previous HGNC Symbols for VSTM5 Gene

  • C11orf90

Previous GeneCards Identifiers for VSTM5 Gene

  • GC11M093552
  • GC11M093554
  • GC11M093570

Summaries for VSTM5 Gene

GeneCards Summary for VSTM5 Gene

VSTM5 (V-Set And Transmembrane Domain Containing 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VSTM5 Gene

Genomics for VSTM5 Gene

Regulatory Elements for VSTM5 Gene

Enhancers for VSTM5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G093849 0.8 ENCODE 9.2 +0.5 548 1.4 HDAC1 CTCF PKNOX1 TAL1 ZNF48 CCNT2 TCF12 NCOR1 HES1 SMARCE1 VSTM5 PANX1 ENSG00000206911
GH11G093814 0.4 ENCODE 12 +35.3 35289 1.9 POLR2A HLF C11orf54 VSTM5 MED17 TAF1D GC11P093800 GC11P093828
GH11G093817 0.2 ENCODE 12 +32.9 32928 0.8 C11orf54 VSTM5 MED17 TAF1D GC11P093828 GC11P093800
GH11G093818 0.2 ENCODE 12 +32.4 32402 0.2 VSTM5 TAF1D MED17 GC11P093828 GC11P093800
GH11G093850 0.6 ENCODE 0.7 -0.2 -249 0.1 HDAC1 PKNOX1 ZNF740 ZKSCAN8 ID3 NR2C2 VSTM5 LOC101060084
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around VSTM5 on UCSC Golden Path with GeneCards custom track

Promoters for VSTM5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for VSTM5 Gene

93,818,232 bp from pter
93,850,531 bp from pter
32,300 bases
Minus strand

Genomic View for VSTM5 Gene

Genes around VSTM5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
VSTM5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for VSTM5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VSTM5 Gene

Proteins for VSTM5 Gene

  • Protein details for VSTM5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    V-set and transmembrane domain-containing protein 5
    Protein Accession:

    Protein attributes for VSTM5 Gene

    200 amino acids
    Molecular mass:
    22377 Da
    Quaternary structure:
    No Data Available

neXtProt entry for VSTM5 Gene

Post-translational modifications for VSTM5 Gene

  • Glycosylation at isoforms=102
  • Modification sites at PhosphoSitePlus

Other Protein References for VSTM5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VSTM5 Gene

Domains & Families for VSTM5 Gene

Gene Families for VSTM5 Gene

Protein Domains for VSTM5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with VSTM5: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for VSTM5 Gene

Function for VSTM5 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for VSTM5 Gene

Localization for VSTM5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VSTM5 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for VSTM5 gene
Compartment Confidence
plasma membrane 3
extracellular 1

Gene Ontology (GO) - Cellular Components for VSTM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with VSTM5: view

Pathways & Interactions for VSTM5 Gene

SuperPathways for VSTM5 Gene

No Data Available

Interacting Proteins for VSTM5 Gene

Gene Ontology (GO) - Biological Process for VSTM5 Gene


No data available for Pathways by source and SIGNOR curated interactions for VSTM5 Gene

Drugs & Compounds for VSTM5 Gene

No Compound Related Data Available

Transcripts for VSTM5 Gene

mRNA/cDNA for VSTM5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for VSTM5 Gene

V-set and transmembrane domain containing 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for VSTM5 Gene

No ASD Table

Relevant External Links for VSTM5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VSTM5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for VSTM5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for VSTM5 Gene

This gene is overexpressed in Brain - Hypothalamus (x6.8), Brain - Frontal Cortex (BA9) (x6.1), Brain - Cortex (x6.0), and Brain - Anterior cingulate cortex (BA24) (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of VSTM5 Gene:


SOURCE GeneReport for Unigene cluster for VSTM5 Gene:

genes like me logo Genes that share expression patterns with VSTM5: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for VSTM5 Gene

Orthologs for VSTM5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for VSTM5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia VSTM5 34 35
  • 86.33 (n)
(Rattus norvegicus)
Mammalia Vstm5 34
  • 81.74 (n)
(Mus musculus)
Mammalia Vstm5 34 16 35
  • 81.07 (n)
(Canis familiaris)
Mammalia VSTM5 34 35
  • 80 (n)
(Monodelphis domestica)
Mammalia VSTM5 35
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia VSTM5 35
  • 72 (a)
(Gallus gallus)
Aves VSTM5 34 35
  • 66.16 (n)
(Anolis carolinensis)
Reptilia VSTM5 35
  • 47 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia vstm5 34
  • 58.33 (n)
(Danio rerio)
Actinopterygii VSTM5 35
  • 32 (a)
Species where no ortholog for VSTM5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VSTM5 Gene

Gene Tree for VSTM5 (if available)
Gene Tree for VSTM5 (if available)

Paralogs for VSTM5 Gene

No data available for Paralogs for VSTM5 Gene

Variants for VSTM5 Gene

Sequence variations from dbSNP and Humsavar for VSTM5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000120295 -- 93,850,833(+) GAAGG(A/T)GGGAA upstream-variant-2KB
rs1000187537 -- 93,849,362(+) ATGTT(A/G)CCCAG intron-variant
rs1000270798 -- 93,826,406(+) TTTTC(-/T)TTTTT intron-variant
rs1000316950 -- 93,838,794(+) CCCTG(C/T)CTAAA intron-variant
rs1000319998 -- 93,843,134(+) TACCA(C/T)AGGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for VSTM5 Gene

Variant ID Type Subtype PubMed ID
dgv695n106 CNV deletion 24896259
esv1952279 CNV deletion 18987734
esv2744923 CNV deletion 23290073
esv2744924 CNV deletion 23290073
esv3250 CNV loss 18987735
esv3548173 CNV deletion 23714750
esv3627294 CNV gain 21293372
esv3627296 CNV loss 21293372
esv3892068 CNV gain 25118596
nsv1122656 CNV deletion 24896259
nsv1147650 CNV deletion 26484159
nsv826039 CNV loss 20364138
nsv957223 CNV deletion 24416366

Variation tolerance for VSTM5 Gene

Gene Damage Index Score: 3.50; 55.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for VSTM5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VSTM5 Gene

Disorders for VSTM5 Gene

Relevant External Links for VSTM5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for VSTM5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for VSTM5 Gene

Publications for VSTM5 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 2 3 4 64

Products for VSTM5 Gene

Sources for VSTM5 Gene

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