VSTM5 Gene
protein-coding GIFtS: 31
GCID: GC11M093552
|
|
V-set and transmembrane domain containing 5(Previous name: chromosome 11 open reading frame 90 )
(Previous symbol: C11orf90)
| |
Aliases
for VSTM5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| V-Set And Transmembrane Domain Containing 51 2 | | C11orf901 2 3 | | LOC3878041 | | Chromosome 11 Open Reading Frame 901 | | V-Set And Transmembrane Domain-Containing Protein 52 |
Export aliases for VSTM5 gene to outside databases |
Summaries
for VSTM5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for VSTM5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for VSTM5
Other transcription factors
Search SABiosciences Chromatin IP Primers for VSTM5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VSTM5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q21 Ensembl cytogenetic band: 11q21 HGNC cytogenetic band: 11q21VSTM5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M093552: view genomic region
(about GC identifiers)
Start:
|
93,551,398 bp from pter |
End:
|
93,583,697 bp from pter |
Size:
|
32,300 bases |
Orientation:
|
minus strand |
|
Proteins
for VSTM5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VSTM5_HUMAN, A8MXK1 (See
protein sequence)Recommended Name: V-set and transmembrane domain-containing protein 5 precursor Size: 200 amino acids; 22377 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)Explore the universe of human proteins at neXtProt for VSTM5: NX_A8MXK1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A8MXK1
VSTM5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001138343.1
ENSEMBL proteins: ENSP00000386607 ENSP00000381277
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
VSTM5 for ontologies About GeneDecksing
VSTM5 Antibody Products:
Assay Products for VSTM5: |
Protein
Domains /
Families
for VSTM5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VSTM5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A8MXK1ProtoNet protein and cluster: A8MXK1 UniProtKB/Swiss-Prot: VSTM5_HUMAN, A8MXK1Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain |
Function
for VSTM5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for VSTM5 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VSTM5 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VSTM5 |
|
Pathways & Interactions
for VSTM5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VSTM5
|
Drugs & Compounds
for VSTM5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VSTM5
Search CenterWatch for drugs/clinical trials and news about VSTM5
|
Transcripts
for VSTM5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VSTM5 gene: NM_001144871.1 Unigene Cluster for VSTM5: V-set and transmembrane domain containing 5 Hs.512252 [show with all ESTs]Unigene Representative Sequence: AL5237813 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000409977(uc010ruc.1) ENST00000398221 ENST00000414919
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for VSTM5 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VSTM5 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VSTM5 |
1 DOTS entry: DT.70102016 6 AceView cDNA sequences: BX090787 AI912018 BF444975 AL562263 AL523781 BG008840
GeneLoc Exon Structure
|
Expression
for VSTM5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VSTM5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGTTTGTA
About this image
See VSTM5 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.512252
SABiosciences Custom PCR Arrays for VSTM5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VSTM5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VSTM5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VSTM5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VSTM5 |
Orthologs
for VSTM5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for VSTM5 gene from 4/9 species (see all 9) About this table
ENSEMBL Gene Tree for VSTM5 (if available)
TreeFam Gene Tree for VSTM5 (if available) |
Paralogs
for VSTM5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for VSTM5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VSTM5 (93551398 - 93583697 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for VSTM5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VSTM5 |
|
Disorders
/ Diseases
for VSTM5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for VSTM5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for VSTM5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with VSTM5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2, 3 Taylor T.D....Sakaki Y. (2006)
|
External Searches for VSTM5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VSTM5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VSTM5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VSTM5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for VSTM5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for VSTM5 gene:
Search GeneIP for patents involving VSTM5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VSTM5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for VSTM5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VSTM5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VSTM5 | | | OriGene Protein Over-expression Lysate for VSTM5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VSTM5 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VSTM5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VSTM5 | | OriGene Custom Protein Services for VSTM5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VSTM5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VSTM5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VSTM5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VSTM5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VSTM5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VSTM5 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for VSTM5 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | VSTM5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for VSTM5 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VSTM5 |
|
|
|
|
