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Aliases for VSTM2L Gene

Aliases for VSTM2L Gene

  • V-Set And Transmembrane Domain Containing 2 Like 2 3
  • C20orf102 3 4
  • V-Set And Transmembrane Domain-Containing Protein 2-Like Protein 3
  • Chromosome 20 Open Reading Frame 102 2
  • DJ1118M15.2 3

External Ids for VSTM2L Gene

Previous Symbols for VSTM2L Gene

  • C20orf102

Summaries for VSTM2L Gene

GeneCards Summary for VSTM2L Gene

VSTM2L (V-Set And Transmembrane Domain Containing 2 Like) is a Protein Coding gene. An important paralog of this gene is VSTM2A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VSTM2L Gene

Genomics for VSTM2L Gene

Genomic Location for VSTM2L Gene

Start:
37,903,097 bp from pter
End:
37,945,350 bp from pter
Size:
42,254 bases
Orientation:
Plus strand

Genomic View for VSTM2L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VSTM2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VSTM2L Gene

Regulatory Elements for VSTM2L Gene

Proteins for VSTM2L Gene

  • Protein details for VSTM2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N03-VTM2L_HUMAN
    Recommended name:
    V-set and transmembrane domain-containing protein 2-like protein
    Protein Accession:
    Q96N03
    Secondary Accessions:
    • E1P5V7
    • Q5JWZ4
    • Q5JWZ5
    • Q8ND45
    • Q9BR37

    Protein attributes for VSTM2L Gene

    Size:
    204 amino acids
    Molecular mass:
    22349 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for VSTM2L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for VSTM2L Gene

Proteomics data for VSTM2L Gene at MOPED

Post-translational modifications for VSTM2L Gene

No Post-translational modifications

Other Protein References for VSTM2L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VSTM2L Gene

Domains for VSTM2L Gene

Gene Families for VSTM2L Gene

HGNC:
  • VSET :Immunoglobulin superfamily / V-set domain containing

Protein Domains for VSTM2L Gene

UniProtKB/Swiss-Prot:

VTM2L_HUMAN
Domain:
  • Contains 1 Ig-like (immunoglobulin-like) domain.:
    • Q96N03
genes like me logo Genes that share domains with VSTM2L: view

Function for VSTM2L Gene

Gene Ontology (GO) - Molecular Function for VSTM2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16713569
genes like me logo Genes that share ontologies with VSTM2L: view

Phenotypes for VSTM2L Gene

GenomeRNAi human phenotypes for VSTM2L:
genes like me logo Genes that share phenotypes with VSTM2L: view

miRNA for VSTM2L Gene

miRTarBase miRNAs that target VSTM2L

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for VSTM2L Gene

Localization for VSTM2L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for VSTM2L Gene COMPARTMENTS Subcellular localization image for VSTM2L gene
Compartment Confidence
extracellular 2
cytoskeleton 1
lysosome 1
nucleus 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for VSTM2L Gene

Pathways for VSTM2L Gene

SuperPathways for VSTM2L Gene

No Data Available

Interacting Proteins for VSTM2L Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000362560%0d%0a9606.ENSP00000386878%0d%0a9606.ENSP00000244769%0d%0a
Selected Interacting proteins: Q96N03-VTM2L_HUMAN ENSP00000362560 for VSTM2L Gene via MINT STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for VSTM2L Gene

None

No data available for Pathways by source for VSTM2L Gene

Transcripts for VSTM2L Gene

mRNA/cDNA for VSTM2L Gene

Unigene Clusters for VSTM2L Gene

V-set and transmembrane domain containing 2 like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for VSTM2L Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: -
SP2: - -
SP3:
SP4: - -
SP5: - - - - -

Relevant External Links for VSTM2L Gene

GeneLoc Exon Structure for
VSTM2L
ECgene alternative splicing isoforms for
VSTM2L

Expression for VSTM2L Gene

mRNA expression in normal human tissues for VSTM2L Gene

mRNA differential expression in normal tissues according to GTEx for VSTM2L Gene

This gene is overexpressed in Brain - Cortex (6.6), Brain - Frontal Cortex (BA9) (5.4), Heart - Atrial Appendage (5.0), Brain - Hippocampus (5.0), Brain - Anterior cingulate cortex (BA24) (4.6), and Brain - Amygdala (4.4).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for VSTM2L Gene

SOURCE GeneReport for Unigene cluster for VSTM2L Gene Hs.517029

genes like me logo Genes that share expressions with VSTM2L: view

Orthologs for VSTM2L Gene

This gene was present in the common ancestor of chordates.

Orthologs for VSTM2L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia VSTM2L 36
  • 99.18 (n)
  • 98.53 (a)
VSTM2L 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia VSTM2L 36
  • 95.42 (n)
  • 98.04 (a)
VSTM2L 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia VSTM2L 36
  • 95.26 (n)
  • 98.04 (a)
VSTM2L 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Vstm2l 36
  • 88.45 (n)
  • 92.08 (a)
Vstm2l 16
Vstm2l 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia VSTM2L 37
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1305725 36
  • 89.27 (n)
  • 92.08 (a)
chicken
(Gallus gallus)
Aves VSTM2L 36
  • 84.75 (n)
  • 87.29 (a)
VSTM2L 37
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia VSTM2L 37
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.19138 36
vstm2l 36
  • 68.12 (n)
  • 60.33 (a)
zebrafish
(Danio rerio)
Actinopterygii vstm2l 36
  • 65.53 (n)
  • 64.63 (a)
vstm2l 37
  • 50 (a)
OneToOne
zgc66133 36
Species with no ortholog for VSTM2L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VSTM2L Gene

ENSEMBL:
Gene Tree for VSTM2L (if available)
TreeFam:
Gene Tree for VSTM2L (if available)

Paralogs for VSTM2L Gene

Paralogs for VSTM2L Gene

Selected SIMAP similar genes for VSTM2L Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with VSTM2L: view

Variants for VSTM2L Gene

Sequence variations from dbSNP and Humsavar for VSTM2L Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs12662 -- 37,945,227(-) AGCTG(C/T)GGCAG utr-variant-3-prime
rs12743 -- 37,945,222(-) CGGCA(A/G)CCAGA utr-variant-3-prime
rs910763 -- 37,905,530(+) CCAGG(A/G)CAGGG intron-variant
rs910764 -- 37,906,595(+) ctgag(A/G)ctcag intron-variant
rs910765 -- 37,940,607(+) tgggc(A/G)agtca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for VSTM2L Gene

Variant ID Type Subtype PubMed ID
nsv833970 CNV Gain 17160897
esv2633566 CNV Insertion 19546169
nsv833971 CNV Gain 17160897

Relevant External Links for VSTM2L Gene

HapMap Linkage Disequilibrium report
VSTM2L

Disorders for VSTM2L Gene

No disorders were found for VSTM2L Gene.

No data available for UniProtKB/Swiss-Prot for VSTM2L Gene

Publications for VSTM2L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. (PMID: 11553796) Ho H.Y. … Kirschner M.W. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3

Products for VSTM2L Gene

Sources for VSTM2L Gene

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