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Aliases for VSTM2A Gene

Aliases for VSTM2A Gene

  • V-Set And Transmembrane Domain Containing 2A 2 3
  • V-Set And Transmembrane Domain Containing 2 2 3
  • VSTM2 3 4
  • V-Set And Transmembrane Domain-Containing Protein 2A 3
  • Hypothetical Protein MGC33530 3

External Ids for VSTM2A Gene

Previous HGNC Symbols for VSTM2A Gene

  • VSTM2

Previous GeneCards Identifiers for VSTM2A Gene

  • GC07P054578
  • GC07P054447

Summaries for VSTM2A Gene

GeneCards Summary for VSTM2A Gene

VSTM2A (V-Set And Transmembrane Domain Containing 2A) is a Protein Coding gene. An important paralog of this gene is VSTM2L.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VSTM2A Gene

Genomics for VSTM2A Gene

Regulatory Elements for VSTM2A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for VSTM2A Gene

54,542,315 bp from pter
54,574,114 bp from pter
31,800 bases
Plus strand

Genomic View for VSTM2A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VSTM2A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VSTM2A Gene

Proteins for VSTM2A Gene

  • Protein details for VSTM2A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    V-set and transmembrane domain-containing protein 2A
    Protein Accession:
    Secondary Accessions:
    • A4D2E9
    • B5MC94

    Protein attributes for VSTM2A Gene

    236 amino acids
    Molecular mass:
    25833 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH28404.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=EAL23809.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for VSTM2A Gene


neXtProt entry for VSTM2A Gene

Proteomics data for VSTM2A Gene at MOPED

Post-translational modifications for VSTM2A Gene

  • Glycosylation at Asn35 and Asn175
  • Modification sites at PhosphoSitePlus

Other Protein References for VSTM2A Gene

No data available for DME Specific Peptides for VSTM2A Gene

Domains for VSTM2A Gene

Gene Families for VSTM2A Gene

  • VSET :Immunoglobulin superfamily / V-set domain containing

Protein Domains for VSTM2A Gene

Suggested Antigen Peptide Sequences for VSTM2A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8TAG5
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
genes like me logo Genes that share domains with VSTM2A: view

Function for VSTM2A Gene

Gene Ontology (GO) - Molecular Function for VSTM2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with VSTM2A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for VSTM2A Gene

Localization for VSTM2A Gene

Subcellular locations from UniProtKB/Swiss-Prot for VSTM2A Gene


Subcellular locations from

Jensen Localization Image for VSTM2A Gene COMPARTMENTS Subcellular localization image for VSTM2A gene
Compartment Confidence
extracellular 3
plasma membrane 2
cytosol 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for VSTM2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with VSTM2A: view

Pathways for VSTM2A Gene

SuperPathways for VSTM2A Gene

No Data Available

Interacting Proteins for VSTM2A Gene

Gene Ontology (GO) - Biological Process for VSTM2A Gene


No data available for Pathways by source for VSTM2A Gene

Transcripts for VSTM2A Gene

Unigene Clusters for VSTM2A Gene

V-set and transmembrane domain containing 2A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VSTM2A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VSTM2A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - -
SP2: - - -
SP3: - -
SP4: - -
SP5: -

Relevant External Links for VSTM2A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VSTM2A Gene

mRNA expression in normal human tissues for VSTM2A Gene

mRNA differential expression in normal tissues according to GTEx for VSTM2A Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (9.3), Brain - Anterior cingulate cortex (BA24) (7.1), Brain - Nucleus accumbens (basal ganglia) (6.5), Brain - Cortex (6.0), Brain - Hypothalamus (5.2), Brain - Amygdala (4.5), and Brain - Caudate (basal ganglia) (4.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for VSTM2A Gene

SOURCE GeneReport for Unigene cluster for VSTM2A Gene Hs.335933

genes like me logo Genes that share expressions with VSTM2A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for VSTM2A Gene

Orthologs for VSTM2A Gene

This gene was present in the common ancestor of chordates.

Orthologs for VSTM2A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia VSTM2A 35
  • 94.2 (n)
  • 93.04 (a)
  • 69 (a)
(Bos Taurus)
Mammalia VSTM2A 35
  • 90.05 (n)
  • 93.36 (a)
  • 83 (a)
(Canis familiaris)
Mammalia VSTM2A 35
  • 92.42 (n)
  • 95.73 (a)
  • 88 (a)
(Mus musculus)
Mammalia Vstm2a 35
  • 89.83 (n)
  • 91.95 (a)
Vstm2a 16
Vstm2a 36
  • 83 (a)
(Monodelphis domestica)
Mammalia VSTM2A 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia VSTM2A 36
  • 83 (a)
(Gallus gallus)
Aves VSTM2A 35
  • 80.97 (n)
  • 85.85 (a)
  • 86 (a)
(Anolis carolinensis)
Reptilia VSTM2A 36
  • 74 (a)
(Danio rerio)
Actinopterygii VSTM2A (1 of 2) 36
  • 51 (a)
VSTM2A (2 of 2) 36
  • 46 (a)
zgc:110852 35
  • 62.85 (n)
  • 55.95 (a)
Species with no ortholog for VSTM2A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VSTM2A Gene

Gene Tree for VSTM2A (if available)
Gene Tree for VSTM2A (if available)

Paralogs for VSTM2A Gene

Paralogs for VSTM2A Gene

Selected SIMAP similar genes for VSTM2A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with VSTM2A: view

Variants for VSTM2A Gene

Sequence variations from dbSNP and Humsavar for VSTM2A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs485006 -- 54,546,889(+) CGCGT(G/T)GGAGC intron-variant
rs490207 -- 54,545,161(-) TGGGG(C/T)GGGGG intron-variant
rs513529 -- 54,542,600(-) TTGCT(C/T)GGCGA utr-variant-5-prime
rs538207 -- 54,542,961(-) ACTTT(A/T)AAAAA intron-variant
rs635315 -- 54,543,345(-) GTCCT(A/G)AACAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for VSTM2A Gene

Variant ID Type Subtype PubMed ID
esv2734425 CNV Deletion 23290073
nsv888052 CNV Gain 21882294
esv2734431 CNV Deletion 23290073
esv2272226 CNV Deletion 18987734

Relevant External Links for VSTM2A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VSTM2A Gene

Disorders for VSTM2A Gene

Relevant External Links for VSTM2A

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with VSTM2A: view

No data available for UniProtKB/Swiss-Prot for VSTM2A Gene

Publications for VSTM2A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  5. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang S.J. … Fox C.S. (BMC Med. Genet. 2007) 48

Products for VSTM2A Gene

Sources for VSTM2A Gene

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