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VSNL1 Gene

protein-coding   GIFtS: 61
GCID: GC02P017720

Visinin-Like 1

  Search for VSNL1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Visinin-Like 11 2     HPCAL32
Hippocalcin-Like Protein 31 2 3     HUVISL12
HLP32 3     VILIP-12
VILIP2 3     Visinin-Like Protein 12
VLP-12 3     VISL13

External Ids:    HGNC: 127221   Entrez Gene: 74472   Ensembl: ENSG000001630327   OMIM: 6008175   UniProtKB: P627603   

Export aliases for VSNL1 gene to outside databases

Previous GC identifers: GC02P017607 GC02P017706 GC02P017643 GC02P017496


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VSNL1 Gene:
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein
is strongly expressed in granule cells of the cerebellum where it associates with membranes in a
calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly
or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been
observed, but their full-length nature has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for VSNL1 Gene:
VSNL1 (visinin-like 1) is a protein-coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is HPCA.

UniProtKB/Swiss-Prot: VISL1_HUMAN, P62760
Function: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner (By
similarity)

Gene Wiki entry for VSNL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the VSNL1 gene promoter:
         AML1a   HSF1 (long)   NF-AT   NF-AT4   NF-AT2   HSF2   HSF1short   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVSNL1 promoter sequence
   Search Chromatin IP Primers for VSNL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VSNL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p24.3   Ensembl cytogenetic band:  2p24.2   HGNC cytogenetic band: 2p24.3

VSNL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VSNL1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P017720:  view genomic region     (about GC identifiers)

Start:
17,720,393 bp from pter      End:
17,838,285 bp from pter
Size:
117,893 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: VISL1_HUMAN, P62760 (See protein sequence)
Recommended Name: Visinin-like protein 1  
Size: 191 amino acids; 22142 Da
Miscellaneous: Probably binds three calcium ions
Secondary accessions: D6W515 P28677 P29103 P42323 Q9UM20

Explore the universe of human proteins at neXtProt for VSNL1: NX_P62760

Explore proteomics data for VSNL1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See VSNL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003376.2  
    ENSEMBL proteins: 
     ENSP00000384014   ENSP00000405511   ENSP00000295156   ENSP00000390124   ENSP00000384719  

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    Search eBioscience for ELISAs for VSNL1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing

    4 InterPro protein domains:
     IPR001125 Recoverin_like
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry P62760

    ProtoNet protein and cluster: P62760

    1 Blocks protein domain: IPB001125 Recoverin family signature

    UniProtKB/Swiss-Prot: VISL1_HUMAN, P62760
    Similarity: Belongs to the recoverin family
    Similarity: Contains 4 EF-hand domains


    Find genes that share domains with VSNL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VISL1_HUMAN, P62760
    Function: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner (By
    similarity)

         Genatlas biochemistry entry for VSNL1:
    visinin-like peptide 1,homolog to Rat RNVP1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    Find genes that share ontologies with VSNL1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VSNL1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VSNL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VSNL1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VSNL1

    miRNA
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    miRTarBase miRNAs that target VSNL1:
    hsa-mir-181b-5p (MIRT003036)

    Block miRNA regulation of human, mouse, rat VSNL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VSNL1 (see all 30):
    hsa-miR-217 hsa-miR-3910 hsa-miR-607 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-miR-4298 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidVSNL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat VSNL1

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    GenScript: all cDNA clones in your preferred vector: VSNL1 (NM_003385)
    Sino Biological Human cDNA Clone for VSNL1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VSNL1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VSNL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    peroxisome2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including VSNL1: 
              Polycomb & Trithorax Target Genes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for VSNL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for VSNL1 (P627602, 3 ENSP000002951564) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2864086 I2D: score=3 STRING: ENSP00000244769
    GFI1BQ5VTD92, 3, ENSP000003447824MINT-2864105 I2D: score=3 STRING: ENSP00000344782
    DTX2Q86UW92, 3, ENSP000003228854MINT-66129 I2D: score=4 STRING: ENSP00000322885
    ACTBP607093, ENSP000003499604I2D: score=2 STRING: ENSP00000349960
    CHRNA4P436813, ENSP000003592854I2D: score=1 STRING: ENSP00000359285
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VSNL1 (VISL1)

    1 HMDB Compound for VSNL1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 Novoseek inferred chemical compound relationship for VSNL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 44.1 20 10531361 (5), 9109541 (3), 12200122 (2), 8593671 (2) (see all 9)



    Find genes that share compounds with VSNL1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for VSNL1 gene: 
    NM_003385.4  

    Unigene Cluster for VSNL1:

    Visinin-like 1
    Hs.444212  [show with all ESTs]
    Unigene Representative Sequence: NM_003385
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000404666 ENST00000457525 ENST00000295156(uc002rcm.3) ENST00000451533
    ENST00000483921 ENST00000406397
    miRNA
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    Block miRNA regulation of human, mouse, rat VSNL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VSNL1 (see all 30):
    hsa-miR-217 hsa-miR-3910 hsa-miR-607 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-miR-4298 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidVSNL1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat VSNL1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VSNL1
    Primer
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    OriGene qPCR primer pairs and template standards for VSNL1
    OriGene qSTAR qPCR primer pairs in human, mouse for VSNL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VSNL1
      QuantiTect SYBR Green Assays in human, mouse, rat VSNL1
      QuantiFast Probe-based Assays in human, mouse, rat VSNL1

    Additional mRNA sequence: 

    AB001104.1 AF039555.1 AK308816.1 BC022012.2 U14747.1 

    11 DOTS entries:

    DT.75111377  DT.100816403  DT.100816400  DT.100816402  DT.121003084  DT.95073477  DT.95217781  DT.100816397 
    DT.95257430  DT.95217815  DT.400300 

    Selected AceView cDNA sequences (see all 187):

    BM727371 CR603967 AL157597 CR621143 BF591289 BX952397 BX440992 CR606471 
    BP347015 AI278768 CR610766 F03489 T16743 T33497 CR590184 AI318387 
    CB117549 F02525 BX508612 F02633 F06242 BX952064 F02034 BM695471 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for VSNL1    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5
    SP1:                                                
    SP2:        -     -                                 
    SP3:                                                


    ECgene alternative splicing isoforms for VSNL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VSNL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAAAAGTAA
    VSNL1 Expression
    About this image


    VSNL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 15 entries
             Thalamus
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 5 entries
             hIPS1
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Ureteric Bud Tip Cells Ureteric Bud
             Ureteric Bud
     
     Lung (Respiratory System)
             Basal Cells Trachea
    VSNL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VSNL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444212

    UniProtKB/Swiss-Prot: VISL1_HUMAN, P62760
    Tissue specificity: Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in
    the cerebrospinal fluid of Alzheimer disease patients (at protein level)

        Pathway & Disease-focused RT2 Profiler PCR Array including VSNL1: 
              Polycomb & Trithorax Target Genes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VSNL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for VSNL1 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vsnl11 , 5 visinin-like 11, 5 91.8(n)1
    100(a)1
      12 (5.58 cM)5
    269501  NM_012038.41  NP_036168.11 
     113252475 
    chicken
    (Gallus gallus)
    Aves VSNL11 visinin-like 1 89.18(n)
    100(a)
      396189  NM_205255.1  NP_990586.1 
    lizard
    (Anolis carolinensis)
    Reptilia VSNL16
    visinin-like 1
    84(a)
    1 ↔ 1
    1(143127052-143286260)
    African clawed frog
    (Xenopus laevis)
    Amphibia CD303254.12   -- 84.46(n)    CD303254.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK395750.12   -- 83.7(n)    CK395750.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nca3 negative regulation of phosphorylation
    calcium more
    71(a)
    (best of 2)
      3 76D8   --


    ENSEMBL Gene Tree for VSNL1 (if available)
    TreeFam Gene Tree for VSNL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for VSNL1 gene
    HPCA2  KCNIP32  KCNIP42  KCNIP12  GUCA1A2  RCVRN2  HPCAL12  GUCA1B2  
    NCALD2  KCNIP22  HPCAL42  NCS12  GUCA1C2  
    Selected SIMAP similar genes for VSNL1 using alignment to 5 protein entries:     VISL1_HUMAN (see all proteins) (see all similar genes):
    HPCAL4    NCALD    DKFZp781K1922    HPCAL1    HPCA    NCS1
    RCVRN    GUCA1A_C250T    KCNIP1    KCNIP4    KCNIP3    KCNIP2
    GUCA1B    GUCA1A_T320C    DKFZp686E1183    GUCA1A    EFCAB1    GUCA1C

    Find genes that share paralogs with VSNL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VSNL1 (see all 2109)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs789936621,2
    C,F--17719841(+) ACATTT/ATTTCC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1439645131,2
    --17719923(+) TAGGTA/GTATCT 1 -- us2k10--------
    rs1897896931,2
    --17719997(+) TTCTCC/GAGAGA 1 -- us2k10--------
    rs1812931441,2
    --17720043(+) GAAATA/CGACCA 1 -- us2k10--------
    rs130061721,2
    C,F--17720203(+) CCAGAG/ACGAAG 1 -- us2k13Minor allele frequency- A:0.26NA WA 240
    rs795016331,2
    C,F--17720270(+) GCGCCG/CTGGTC 1 -- us2k11Minor allele frequency- C:0.06NA 120
    rs621304411,2
    C,F--17720430(+) AGTTCC/ATGGGT 1 -- us2k12Minor allele frequency- A:0.07NA 122
    rs75938811,2
    C,F,A,H--17720520(+) GACTTG/CTCTGG 1 -- us2k1 ese36Minor allele frequency- C:0.14NS EA NA 538
    rs762609171,2
    C,F--17720675(+) GGTAGG/ATCAAC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1850759951,2
    --17720722(+) ACGCTC/GTGCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for VSNL1 (17720393 - 17838285 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for VSNL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719748CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VSNL1
    DNA2.0 Custom Variant and Variant Library Synthesis for VSNL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600817    OMIM disorders: --


    Find genes that share disorders with VSNL1           About GenesLikeMe

    1 Novoseek inferred disease relationship for VSNL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 37.4 2 11173883 (1), 19264852 (1)

    Genetic Association Database (GAD): VSNL1
    Human Genome Epidemiology (HuGE) Navigator: VSNL1 (1 document)

    Export disorders for VSNL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VSNL1 gene, integrated from 10 sources (see all 53):
    (articles sorted by number of sources associating them with VSNL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sequence characterization and genetic mapping of the human VSNL1 gene, a homologue of the rat visinin-like peptide RNVP1. (PubMed id 8530085)1, 2, 3, 9 Polymeropoulos M.H.... Lennon G.G. (Genomics 1995)
    2. Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes. (PubMed id 10520747)1, 2, 9 Kobayashi M.... Takamatsu K. (DNA Seq. 1998)
    3. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PubMed id 22005930)1, 4 Hollingworth P....Williams J. (Mol. Psychiatry 2012)
    4. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PubMed id 20347265)1, 4 Xu Y....Liu P. (Schizophr. Res. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Electron microscopic localization of gamma- and beta II-subspecies of protein kinase C in rat hippocampus. (PubMed id 2202488)1, 3 Kose A....Tanaka C. (Brain Res. 1990)
    7. Involvement of visinin-like protein-1 (VSNL-1) in regulating proliferative and invasive properties of neuroblastoma. (PubMed id 17615261)1, 9 Xie Y....Ren Y. (Carcinogenesis 2007)
    8. The neuronal calcium-sensor protein VILIP modulates cyclic AMP accumulation in stably transfected C6 glioma cells: amino-terminal myristoylation determines functional activity. (PubMed id 9109541)1, 9 Braunewell K.H....Gundelfinger E.D. (J. Neurochem. 1997)
    9. The neuronal EF-hand Ca(2+)-binding protein VILIP: interaction with cell membrane and actin-based cytoskeleton. (PubMed id 8780737)1, 9 Lenz S.E....Gundelfinger E.D. (Biochem. Biophys. Res. Commun. 1996)
    10. Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart. (PubMed id 20079378)1, 9 Buttgereit J....Bader M. (Regul. Pept. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7447 HGNC: 12722 AceView: VSNL1 Ensembl:ENSG00000163032 euGenes: HUgn7447
    ECgene: VSNL1 H-InvDB: VSNL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VSNL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VSNL1 gene:
    Search GeneIP for patents involving VSNL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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