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Aliases for VSIG10 Gene

Aliases for VSIG10 Gene

  • V-Set And Immunoglobulin Domain Containing 10 2 3

External Ids for VSIG10 Gene

Previous GeneCards Identifiers for VSIG10 Gene

  • GC12M116987
  • GC12M118501
  • GC12M115511

Summaries for VSIG10 Gene

GeneCards Summary for VSIG10 Gene

VSIG10 (V-Set And Immunoglobulin Domain Containing 10) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VSIG10 Gene

Genomics for VSIG10 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for VSIG10 Gene

118,063,593 bp from pter
118,136,026 bp from pter
72,434 bases
Minus strand

Genomic View for VSIG10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VSIG10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VSIG10 Gene

No data available for Regulatory Elements for VSIG10 Gene

Proteins for VSIG10 Gene

  • Protein details for VSIG10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    V-set and immunoglobulin domain-containing protein 10
    Protein Accession:
    Secondary Accessions:
    • Q9NWQ7

    Protein attributes for VSIG10 Gene

    540 amino acids
    Molecular mass:
    59217 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for VSIG10 Gene


neXtProt entry for VSIG10 Gene

Proteomics data for VSIG10 Gene at MOPED

Post-translational modifications for VSIG10 Gene

  • Glycosylation at Asn39, Asn46, Asn70, Asn108, Asn138, Asn171, Asn180, Asn198, and Asn326
  • Modification sites at PhosphoSitePlus

Other Protein References for VSIG10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VSIG10 Gene

Domains for VSIG10 Gene

Protein Domains for VSIG10 Gene

Suggested Antigen Peptide Sequences for VSIG10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
  • Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
genes like me logo Genes that share domains with VSIG10: view

Function for VSIG10 Gene

Gene Ontology (GO) - Molecular Function for VSIG10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with VSIG10: view

Phenotypes for VSIG10 Gene

GenomeRNAi human phenotypes for VSIG10:
genes like me logo Genes that share phenotypes with VSIG10: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VSIG10

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for VSIG10 Gene

Localization for VSIG10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VSIG10 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for VSIG10 Gene COMPARTMENTS Subcellular localization image for VSIG10 gene
Compartment Confidence
plasma membrane 3
cytosol 1

Gene Ontology (GO) - Cellular Components for VSIG10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with VSIG10: view

Pathways for VSIG10 Gene

SuperPathways for VSIG10 Gene

No Data Available

Interacting Proteins for VSIG10 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000352172 for VSIG10 Gene via STRING

Gene Ontology (GO) - Biological Process for VSIG10 Gene


No data available for Pathways by source for VSIG10 Gene

Transcripts for VSIG10 Gene

Unigene Clusters for VSIG10 Gene

V-set and immunoglobulin domain containing 10:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VSIG10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VSIG10 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP3: - - -
SP4: -
SP5: -

Relevant External Links for VSIG10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VSIG10 Gene

mRNA expression in normal human tissues for VSIG10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for VSIG10 Gene

This gene is overexpressed in Placenta (35.5) and Spleen (33.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for VSIG10 Gene

SOURCE GeneReport for Unigene cluster for VSIG10 Gene Hs.187624

genes like me logo Genes that share expressions with VSIG10: view

Expression partners for VSIG10 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for VSIG10 Gene

Orthologs for VSIG10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for VSIG10 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia VSIG10 35
  • 84.05 (n)
  • 77.28 (a)
VSIG10 36
  • 75 (a)
(Canis familiaris)
Mammalia VSIG10 35
  • 82.9 (n)
  • 78.15 (a)
VSIG10 36
  • 78 (a)
(Mus musculus)
Mammalia Vsig10 35
  • 75.68 (n)
  • 69.71 (a)
Vsig10 16
Vsig10 36
  • 64 (a)
(Pan troglodytes)
Mammalia VSIG10 35
  • 97.52 (n)
  • 96.09 (a)
VSIG10 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Vsig10 35
  • 75.95 (n)
  • 71.21 (a)
(Monodelphis domestica)
Mammalia VSIG10 36
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia VSIG10 36
  • 41 (a)
(Gallus gallus)
Aves VSIG10 36
  • 39 (a)
(Anolis carolinensis)
Reptilia VSIG10 36
  • 36 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia vsig10 35
  • 50.53 (n)
  • 42.47 (a)
(Danio rerio)
Actinopterygii vsig10 35
  • 45.42 (n)
  • 34.36 (a)
vsig10 36
  • 29 (a)
Species with no ortholog for VSIG10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VSIG10 Gene

Gene Tree for VSIG10 (if available)
Gene Tree for VSIG10 (if available)

Paralogs for VSIG10 Gene

No data available for Paralogs for VSIG10 Gene

Variants for VSIG10 Gene

Sequence variations from dbSNP and Humsavar for VSIG10 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs8239 -- 118,064,662(+) GCAAA(A/G)GACAA utr-variant-3-prime, downstream-variant-500B
rs1128304 -- 118,065,132(-) TAACA(C/G)TAAAT utr-variant-3-prime, nc-transcript-variant
rs1137584 -- 118,080,433(-) tctgt(A/G)atttc intron-variant
rs1137585 -- 118,080,432(-) ctgta(A/G)tttca intron-variant
rs1137586 -- 118,080,406(-) gaggc(A/G)ggtgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for VSIG10 Gene

Variant ID Type Subtype PubMed ID
nsv899546 CNV Gain 21882294
esv2746451 CNV Deletion 23290073
esv2148077 CNV Deletion 18987734
nsv53654 CNV Loss 16902084
esv2746453 CNV Deletion 23290073
esv2746454 CNV Deletion 23290073
nsv52642 CNV Loss 16902084

Relevant External Links for VSIG10 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VSIG10 Gene

Disorders for VSIG10 Gene

Relevant External Links for VSIG10

Genetic Association Database (GAD)

No disorders were found for VSIG10 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for VSIG10 Gene

Publications for VSIG10 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for VSIG10 Gene

Sources for VSIG10 Gene

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