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VSIG1 Gene

protein-coding   GIFtS: 51
GCID: GC0XP107288

V-Set And Immunoglobulin Domain Containing 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
V-Set And Immunoglobulin Domain Containing 11 2     1700062D20Rik2
GPA342 3 5     dJ889N15.12
Cell Surface A33 Antigen2 3     V-Set And Immunoglobulin Domain-Containing Protein 12
Glycoprotein A342 3     

External Ids:    HGNC: 286751   Entrez Gene: 3405472   Ensembl: ENSG000001018427   OMIM: 3006205   UniProtKB: Q86XK73   

Export aliases for VSIG1 gene to outside databases

Previous GC identifers: GC0XP107094 GC0XP107174 GC0XP096911


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VSIG1 Gene:
This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple
glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP)
repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric,
esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Dec 2009)

GeneCards Summary for VSIG1 Gene:
VSIG1 (V-set and immunoglobulin domain containing 1) is a protein-coding gene. An important paralog of this gene is CLMP.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VSIG1 gene promoter:
         FOXF2   MyoD   FOXO3   NF-kappaB   FOXO3b   SRY   FOXO3a   LyF-1   NF-kappaB1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVSIG1 promoter sequence
   Search Chromatin IP Primers for VSIG1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VSIG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.3   Ensembl cytogenetic band:  Xq22.3   HGNC cytogenetic band: Xq22.3

VSIG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VSIG1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP107288:  view genomic region     (about GC identifiers)

Start:
107,288,200 bp from pter      End:
107,322,414 bp from pter
Size:
34,215 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: VSIG1_HUMAN, Q86XK7 (See protein sequence)
Recommended Name: V-set and immunoglobulin domain-containing protein 1 precursor  
Size: 387 amino acids; 41811 Da
Sequence caution: Sequence=CAE45954.1; Type=Erroneous initiation;
Secondary accessions: C9J4P2 Q6MZS4
Alternative splicing: 2 isoforms:  Q86XK7-1   Q86XK7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VSIG1: NX_Q86XK7

Explore proteomics data for VSIG1 at MOPED

Post-translational modifications: 

  • Highly N-glycosylated. Appears not to contain significant amounts of O-linked carbohydrates or sialic acid in its
    sugar moieties1
  • Glycosylation2 at Asn32, Asn38, Asn133, Asn200, Asn219
  • Modification sites at PhosphoSitePlus

  • See VSIG1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001164024.1  NP_872413.1  

    ENSEMBL proteins: 
     ENSP00000217957   ENSP00000407102   ENSP00000402219  

    VSIG1 Human Recombinant Protein Products:

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    Novus Biologicals VSIG1 Protein
    Novus Biologicals VSIG1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for VSIG1

     
    Search eBioscience for Proteins for VSIG1 

    VSIG1 Antibody Products:

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    ThermoFisher Antibodies for VSIG1
    LSBio Antibodies in human, mouse, rat for VSIG1

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    Cloud-Clone Corp. ELISAs for VSIG1
    Cloud-Clone Corp. CLIAs for VSIG1
    Search eBioscience for ELISAs for VSIG1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing
    VSET: Immunoglobulin superfamily / V-set domain containing

    Selected InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry Q86XK7

    ProtoNet protein and cluster: Q86XK7

    1 Blocks protein domain: IPB003598 Immunoglobulin C-2 type

    UniProtKB/Swiss-Prot: VSIG1_HUMAN, Q86XK7
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    Find genes that share domains with VSIG1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with VSIG1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for VSIG1:
     Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VSIG1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VSIG1
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    miRNA
    Products:
        
    miRTarBase miRNAs that target VSIG1:
    hsa-mir-142-3p (MIRT021542)

    Block miRNA regulation of human, mouse, rat VSIG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VSIG1 (see all 10):
    hsa-miR-144* hsa-miR-499-3p hsa-miR-496 hsa-miR-3914 hsa-miR-873 hsa-miR-23b* hsa-miR-4279 hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidVSIG1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for VSIG1
    Predesigned siRNA for gene silencing in human, mouse, rat VSIG1

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: VSIG1 (NM_019086)
    Sino Biological Human cDNA Clone for VSIG1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VSIG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VSIG1

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VSIG1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VSIG1_HUMAN, Q86XK7: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with VSIG1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VSIG1
    Interactions:

        Search GeneGlobe Interaction Network for VSIG1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VSIG1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for VSIG1 gene (2 alternative transcripts): 
    NM_001170553.1  NM_182607.4  

    Unigene Cluster for VSIG1:

    V-set and immunoglobulin domain containing 1
    Hs.177164  [show with all ESTs]
    Unigene Representative Sequence: NM_001170553
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000217957 ENST00000458383 ENST00000485533 ENST00000479635 ENST00000415430(uc011msk.2 uc004eno.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat VSIG1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VSIG1 (see all 10):
    hsa-miR-144* hsa-miR-499-3p hsa-miR-496 hsa-miR-3914 hsa-miR-873 hsa-miR-23b* hsa-miR-4279 hsa-miR-493*
    SwitchGear 3'UTR luciferase reporter plasmidVSIG1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for VSIG1
    Predesigned siRNA for gene silencing in human, mouse, rat VSIG1
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: VSIG1 (NM_019086)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VSIG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VSIG1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for VSIG1
    OriGene qSTAR qPCR primer pairs in human, mouse for VSIG1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VSIG1
      QuantiTect SYBR Green Assays in human, mouse, rat VSIG1
      QuantiFast Probe-based Assays in human, mouse, rat VSIG1

    Additional mRNA sequence: 

    AK292472.1 AK301311.1 AK301783.1 AK315846.1 BC043216.2 BX640913.1 BX648658.1 

    2 DOTS entries:

    DT.95148618  DT.121322785 

    19 AceView cDNA sequences:

    BQ027344 BM782237 BC043216 BX640913 NM_182607 AI581519 AW864876 BX648658 
    BG772843 BI459739 CD358701 AI803868 BI464536 CD690155 AW085312 CD698346 
    BQ435687 BQ376500 BE939144 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VSIG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCATATTTC
    VSIG1 Expression
    About this image


    VSIG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)
             T Helper Cells Peripheral Blood
     
     Testis (Reproductive System)
     
     Stomach (Gastrointestinal Tract)
    VSIG1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VSIG1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.177164

    UniProtKB/Swiss-Prot: VSIG1_HUMAN, Q86XK7
    Tissue specificity: Detected only in stomach mucosa and testis, and to a much lesser level in pancreas (at protein
    level). Detected in gastric cancers (31%), esophageal carcinomas (50%) and ovarian cancers (23%)

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    QuantiFast Probe-based Assays in human, mouse, rat VSIG1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VSIG1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for VSIG1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vsig11 V-set and immunoglobulin domain containing 1 75.76(n)
    72.21(a)
      78789  NM_030181.3  NP_084457.2 
    chicken
    (Gallus gallus)
    Aves VSIG11 V-set and immunoglobulin domain containing 1 57.48(n)
    48.3(a)
      414795  NM_001001745.1  NP_001001745.1 
    lizard
    (Anolis carolinensis)
    Reptilia VSIG16
    V-set and immunoglobulin domain containing 1
    38(a)
    1 ↔ 1
    GL343202.1(3855496-3970150)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia vsig11 V-set and immunoglobulin domain containing 1 52.65(n)
    45.31(a)
      100127183  NM_001112909.1  NP_001106380.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1656046
    zgc:165604
    27(a)
    many ↔ many
    21(26952777-26964610) ENSDARG00000021241


    ENSEMBL Gene Tree for VSIG1 (if available)
    TreeFam Gene Tree for VSIG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for VSIG1 gene
    CLMP2  ESAM2  VSIG82  GPA332  CXADR2  VSIG22  C1orf2042  IGSF112  
    2 SIMAP similar genes for VSIG1 using alignment to 2 protein entries:     VSIG1_HUMAN (see all proteins):
    VSIG2    GPA33

    Find genes that share paralogs with VSIG1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VSIG1 (see all 512)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1876282301,2
    --107257957(+) TTGGAA/GCATGA 2 -- us2k10--------
    rs1457606851,2
    C--107258019(+) CCAGGA/GGGCCG 2 -- us2k10--------
    rs15476261,2
    C,F,A,H--107258064(-) TTGCAT/CGTCTC 2 -- us2k110Minor allele frequency- C:0.28NA EA NS WA CSA 675
    rs1470848081,2
    C--107258243(+) AGACTC/TATATT 2 -- us2k10--------
    rs1911466341,2
    --107258311(+) TGGGAC/TACGCT 2 -- us2k10--------
    rs1840723821,2
    --107258333(+) TGGGAA/GCTGCC 2 -- us2k10--------
    rs1871142671,2
    C--107258366(+) CTGGAA/GGGATT 2 -- us2k10--------
    rs59629321,2
    C,F,H--107258482(+) GCTAGG/AGTGGT 2 -- us2k113Minor allele frequency- A:0.07NS EA CSA 1979
    rs1916256691,2
    --107258736(+) TTTCCC/TGTAAA 2 -- us2k10--------
    rs1853381021,2
    --107258765(+) AACATA/GTCACT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for VSIG1 (107288200 - 107322414 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for VSIG1: --
    Human Gene Mutation Database (HGMD): VSIG1
    Locus Specific Mutation Databases (LSDB): VSIG1

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VSIG1
    DNA2.0 Custom Variant and Variant Library Synthesis for VSIG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300620    OMIM disorders: --


    Find genes that share disorders with VSIG1           About GenesLikeMe


    Export disorders for VSIG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VSIG1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with VSIG1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Glycoprotein A34, a novel target for antibody-based cancer immunotherapy. (PubMed id 16405301)1, 2, 9 Scanlan M.J.... Jungbluth A.A. (Cancer Immun. 2006)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Decreased expression of V-set and immunoglobulin domain containing 1 (VSIG1) is associated with poor prognosis in primary gastric cancer. (PubMed id 22095633)1 Chen Y....Li Q. (J Surg Oncol 2012)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    5. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 340547 HGNC: 28675 AceView: VSIG1 Ensembl:ENSG00000101842 euGenes: HUgn340547
    ECgene: VSIG1 H-InvDB: VSIG1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VSIG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VSIG1 gene:
    Search GeneIP for patents involving VSIG1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     EMD Millipore genomic analysis products

      
     Antibodies for VSIG1 (VSIG1)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for VSIG1  
     OriGene qPCR primer pairs and template standards for VSIG1   OriGene Protein Over-expression Lysate for VSIG1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for VSIG1  
     OriGene qSTAR qPCR primer pairs in human, mouse for VSIG1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for VSIG1   OriGene Custom Protein Services for VSIG1  

     
     
     Block miRNA regulation of human, mouse, rat VSIG1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing VSIG1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VSIG1 Predesigned siRNA for gene silencing in human, mouse, rat VSIG1
     QuantiFast Probe-based Assays in human, mouse, rat VSIG1 QuantiTect SYBR Green Assays in human, mouse, rat VSIG1
     Custom PCR Arrays for VSIG1 Search Chromatin IP Primers for VSIG1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VSIG1  Search GeneGlobe Interaction Network for VSIG1
     Regulatory tfbs in VSIG1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for VSIG1 GenScript cDNA clones with any tag delivered in your preferred vector for VSIG1
     GenScript Custom Assay Services for VSIG1 GenScript Custom overexpressing Cell Line Services for VSIG1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for VSIG1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for VSIG1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
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     Protein A/G/L resins
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     VSIG1 antibodies
     VSIG1 proteins
     VSIG1 lysates
     Antibodies for VSIG1
     See all of Abcam's Antibodies, Kits and Proteins for VSIG1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for VSIG1
     Antibodies for VSIG1
     ELISAs for VSIG1
     CLIAs for VSIG1



     Browse ESI BIO Cell Lines and PureStem Progenitors for VSIG1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VSIG1
     SwitchGear 3'UTR luciferase reporter plasmids for VSIG1
     SwitchGear Promoter luciferase reporter plasmids for VSIG1
     ThermoFisher Antibodies for VSIG1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VSIG1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VSIG1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VSIG1
     LSBio Antibodies in human, mouse, rat for VSIG1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for VSIG1
      Search eBioscience for proteins for VSIG1
      Search eBioscience for elisas for VSIG1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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