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Aliases for VRTN Gene

Aliases for VRTN Gene

  • Vertebrae Development Associated 2 3
  • Vertebrae Development Homolog (Pig) 2 3
  • C14orf115 3 4
  • Chromosome 14 Open Reading Frame 115 2
  • Vertnin 3

External Ids for VRTN Gene

Previous HGNC Symbols for VRTN Gene

  • C14orf115

Previous GeneCards Identifiers for VRTN Gene

  • GC14P074817

Summaries for VRTN Gene

GeneCards Summary for VRTN Gene

VRTN (Vertebrae Development Associated) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding and transposase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VRTN Gene

Genomics for VRTN Gene

Genomic Location for VRTN Gene

74,303,069 bp from pter
74,360,008 bp from pter
56,940 bases
Plus strand

Genomic View for VRTN Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VRTN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VRTN Gene

No data available for Regulatory Elements for VRTN Gene

Proteins for VRTN Gene

  • Protein details for VRTN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • Q9NVC7

    Protein attributes for VRTN Gene

    702 amino acids
    Molecular mass:
    78260 Da
    Quaternary structure:
    No Data Available

neXtProt entry for VRTN Gene

Proteomics data for VRTN Gene at MOPED

Post-translational modifications for VRTN Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for VRTN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VRTN Gene

Domains for VRTN Gene

Protein Domains for VRTN Gene

Suggested Antigen Peptide Sequences for VRTN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the vertnin family.
  • Belongs to the vertnin family.
genes like me logo Genes that share domains with VRTN: view

No data available for Gene Families for VRTN Gene

Function for VRTN Gene

Gene Ontology (GO) - Molecular Function for VRTN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0004803 transposase activity IEA --
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with VRTN: view

Phenotypes for VRTN Gene

GenomeRNAi human phenotypes for VRTN:
genes like me logo Genes that share phenotypes with VRTN: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VRTN

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for VRTN Gene

Localization for VRTN Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for VRTN Gene

Pathways for VRTN Gene

SuperPathways for VRTN Gene

No Data Available

Interacting Proteins for VRTN Gene

Selected Interacting proteins: Q9H8Y1-VRTN_HUMAN for VRTN Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for VRTN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006313 transposition, DNA-mediated IEA --
genes like me logo Genes that share ontologies with VRTN: view

No data available for Pathways by source for VRTN Gene

Transcripts for VRTN Gene

mRNA/cDNA for VRTN Gene

(5) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for VRTN Gene

Vertebrae development associated:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VRTN

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VRTN Gene

No ASD Table

Relevant External Links for VRTN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for VRTN Gene

mRNA expression in normal human tissues for VRTN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for VRTN Gene

This gene is overexpressed in Testis (38.5).

SOURCE GeneReport for Unigene cluster for VRTN Gene Hs.578167

genes like me logo Genes that share expressions with VRTN: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for VRTN Gene

Orthologs for VRTN Gene

This gene was present in the common ancestor of chordates.

Orthologs for VRTN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia VRTN 35
  • 84.25 (n)
  • 84.74 (a)
  • 83 (a)
(Canis familiaris)
Mammalia VRTN 35
  • 84.74 (n)
  • 83.53 (a)
  • 82 (a)
(Mus musculus)
Mammalia Vrtn 35
  • 79.05 (n)
  • 75.43 (a)
Vrtn 16
Vrtn 36
  • 70 (a)
(Pan troglodytes)
Mammalia LOC101057922 35
  • 98.86 (n)
  • 98.16 (a)
(Rattus norvegicus)
Mammalia Vrtn 35
  • 81.13 (n)
  • 78.6 (a)
(Monodelphis domestica)
Mammalia VRTN 36
  • 63 (a)
(Gallus gallus)
Aves VRTN 35
  • 66.62 (n)
  • 60.24 (a)
  • 57 (a)
(Anolis carolinensis)
Reptilia VRTN 36
  • 53 (a)
(Danio rerio)
Actinopterygii vrtn 35
  • 53.85 (n)
  • 47.69 (a)
vrtn 36
  • 44 (a)
Species with no ortholog for VRTN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VRTN Gene

Gene Tree for VRTN (if available)
Gene Tree for VRTN (if available)

Paralogs for VRTN Gene

No data available for Paralogs for VRTN Gene

Variants for VRTN Gene

Sequence variations from dbSNP and Humsavar for VRTN Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs999714 -- 74,349,967(+) TTTCA(G/T)ATCAC intron-variant
rs2108759 -- 74,355,193(-) aaaat(C/T)tcaat intron-variant
rs2232031 -- 74,356,846(+) GAGTG(C/T)GAAGG reference, synonymous-codon
rs2232032 - 74,356,940(+) CTGGC(C/T)TCCAG reference, missense
rs2232033 -- 74,357,299(+) TCCAA(C/T)GTGTG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for VRTN Gene

Variant ID Type Subtype PubMed ID
nsv902096 CNV Gain 21882294

Relevant External Links for VRTN Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VRTN Gene

Disorders for VRTN Gene

No disorders were found for VRTN Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for VRTN Gene

Publications for VRTN Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Identification of a second gene associated with variation in vertebral number in domestic pigs. (PMID: 21232157) Mikawa S. … Awata T. (BMC Genet. 2011) 2 3
  4. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4
  5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4

Products for VRTN Gene

Sources for VRTN Gene

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