VRK3 Gene
protein-coding GIFtS: 56
GCID: GC19M050479
|
|
vaccinia related kinase 3
| |
Aliases
for VRK3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Vaccinia Related Kinase 31 2 | | Serine/Threonine-Protein Pseudokinase VRK32 3 | | Vaccinia-Related Kinase 32 3 | | Inactive Serine/Threonine-Protein Kinase VRK32 | | Serine/Threonine-Protein Kinase VRK32 |
Export aliases for VRK3 gene to outside databasesPrevious GC identifers: GC19M055155 GC19M055171 GC19M046855 |
Summaries
for VRK3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for VRK3:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In bothhuman and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinaseshave been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. Theprotein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues andits protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding differentisoforms. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: VRK3_HUMAN, Q8IV63Function: Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specificallydephosphorylates and inactivates ERK in the nucleus (By similarity)
|
Genomic Views
for VRK3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the VRK3 gene promoter:
STAT5B NCX/Ncx Bach2 STAT5A AREB6 E2F-1 E2F Msx-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for VRK3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VRK3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.33VRK3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M050479: view genomic region
(about GC identifiers)
Start:
|
50,479,724 bp from pter |
End:
|
50,528,805 bp from pter |
Size:
|
49,082 bases |
Orientation:
|
minus strand |
|
Proteins
for VRK3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VRK3_HUMAN, Q8IV63 (See
protein sequence)Recommended Name: Inactive serine/threonine-protein kinase VRK3 Size: 474 amino acids; 52881 Da
Subunit: Interacts with DUSP3 (By similarity). Interacts with RAN
Subcellular location: Nucleus
Caution: Inactive as a kinase due to its inability to bind ATP (PubMed:19141289)
1 PDB 3D structure from  and Proteopedia  for VRK3:2JII (3D)
Secondary accessions: A6NEG5 A8KA53 Q502Y2 Q9P2V8Alternative splicing: 3 isoforms: Q8IV63-1 Q8IV63-2 Q8IV63-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for VRK3: NX_Q8IV63
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IV63
VRK3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001020949.1 NP_057524.3
ENSEMBL proteins: ENSP00000324636 ENSP00000366210 ENSP00000414907 ENSP00000402958
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
VRK3 for ontologies About GeneDecksing
VRK3 Antibody Products:
Assay Products for VRK3: |
Protein
Domains /
Families
for VRK3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VRK3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IV63ProtoNet protein and cluster: Q8IV63 UniProtKB/Swiss-Prot: VRK3_HUMAN, Q8IV63Similarity: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamilySimilarity: Contains 1 protein kinase domain |
Function
for VRK3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VRK3_HUMAN, Q8IV63Function: Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specificallydephosphorylates and inactivates ERK in the nucleus (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): VRK3 (NM_001025778) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VRK3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VRK3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VRK3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
VRK3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for VRK3:
Animal Models:
1 MGI phenotypic allele  for Vrk3 (no phenotypes)
VRK3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for VRK3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction Erk Interactions: Inhibition of Erk | | | 2 | MAP Kinase Signaling | | | 3 | Cell Cycle / Checkpoint Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for VRK3
2 
Cell Signaling Technology (CST) Pathways for VRK3
1  GeneGo (Thomson Reuters) Pathway for VRK3
VRK3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VRK3
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/8 Interacting proteins for VRK3 (Q8IV632, 3 ENSP000003246364) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0032516 | positive regulation of phosphoprotein phosphatase activity |
-- | -- | | GO:0070373 | negative regulation of ERK1 and ERK2 cascade |
-- | -- |
VRK3 for ontologies About GeneDecksing
|
Drugs & Compounds
for VRK3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VRK3
2 HMDB Compounds for VRK3 About this table
Search CenterWatch for drugs/clinical trials and news about VRK3
|
Transcripts
for VRK3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VRK3 gene (2 alternative transcripts): NM_001025778.1 NM_016440.3 Unigene Cluster for VRK3: Vaccinia related kinase 3 Hs.443330 [show with all ESTs]Unigene Representative Sequence: AK1238924 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000316763(uc002prg.2 uc002prh.1 uc002prk.2 uc010ent.2 uc002prl.3 uc010ybn.1)
ENST00000377011(uc002pri.1) ENST00000443401(uc010ens.2 uc010ybl.1 uc010ybm.1)
ENST00000424804
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): VRK3 (NM_001025778) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VRK3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VRK3 |
Additional cDNA sequence: AB031052.1 AF514788.1 AK123892.1 AK125747.1 AK225154.1 AK292918.1 AK294802.1 AK303010.1 AK303529.1 AK311220.1 BC003546.1 BC023556.2 BC095449.1 24/25 DOTS entries (see all 25): DT.101979050 DT.444386 DT.100836317 DT.91756372 DT.40120674 DT.411371 DT.40123017 DT.95230894 DT.424334 DT.100836321 DT.97791785 DT.97848304 DT.75124205 DT.95230903 DT.121502554 DT.92020322 DT.100836318 DT.100037067 DT.100836315 DT.121502544 DT.121502573 DT.91756370 DT.121502574 DT.91870679 24/377 AceView cDNA sequences (see all 377): BU195622 BQ438286 BP335032 BQ691691 AW628001 BX402717 AI823329 BQ063097 CR606658 CA307083 BX479817 BM707696 BU733229 BM922031 CD359131 BI913963 CA423008 BQ066426 BM906449 BM553868 BQ100960 AA436646 CD359612 BM553949
GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for VRK3 (see all 15) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21a | · | 21b |
|---|
|
| SP1: | - | | - | | | | | | | | | | | | |
| SP2: | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for VRK3
|
Expression
for VRK3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VRK3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGAGGAACA
About this image
See VRK3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VRK3
SOURCE GeneReport for Unigene cluster: Hs.443330
SABiosciences Custom PCR Arrays for VRK3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VRK3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VRK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VRK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VRK3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VRK3 |
Orthologs
for VRK3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for VRK3 gene from 8/25 species (see all 25) About this table
ENSEMBL Gene Tree for VRK3 (if available)
TreeFam Gene Tree for VRK3 (if available) |
Paralogs
for VRK3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for VRK3 gene
- VRK12 CSNK1G32 VRK22 CSNK1D2 CSNK1G22 CSNK1A12 CSNK1A1L2 TTBK12
- CSNK1G12 CSNK1E2 TTBK22
2 SIMAP similar genes for VRK3 using alignment to 13 protein entries: VRK3_HUMAN (see all proteins):VRK1 VRK2
VRK3 for paralogs About GeneDecksing
|
Genomic Variants
for VRK3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VRK3 (50479724 - 50528805 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 16 variations for VRK3
4 CNVs: 67580 8874 58885 32261
12 Indels: 78233 78229 89287 89286 78234 78228 78231 78235 89284 78232 78230 89285 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VRK3 |
|
Disorders
/ Diseases
for VRK3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
VRK3 for disorders About GeneDecksing
1  disease for VRK3: About MalaCardsvaccinia
1 disease from the University of Copenhagen DISEASES database for VRK3:Vaccinia Human Genome Epidemiology (HuGE) Navigator: VRK3 (1 document)
Export disorders for VRK3 gene to outside databases
|
Publications
for VRK3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VRK3 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with VRK3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of three paralogous members of the Mammalian vaccinia related kinase family. (PubMed id 14645249)1, 2, 9 Nichols R.J. and Traktman P. (2004)
- Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities. (PubMed id 18617507)1, 2 Sanz-Garcia M....Lazo P.A. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. (PubMed id 19141289)2 Scheeff E.D.... Manning G. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
|
External Searches for VRK3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VRK3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VRK3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VRK3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for VRK3 gene:
Search GeneIP for patents involving VRK3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VRK3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for VRK3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VRK3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VRK3 | | | OriGene Protein Over-expression Lysate for VRK3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VRK3 | | OriGene 3'-UTR Clone for VRK3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VRK3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for VRK3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VRK3 | | OriGene Custom Protein Services for VRK3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VRK3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VRK3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VRK3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VRK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VRK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VRK3 |
| |
 |  |  |  | |
| | Antibodies & Assays for VRK3 |
| | | | Search Tocris compounds for VRK3 |
| |  |  |  |  | | | | | | Recombinant Protein for VRK3 |
|
 |
 |
 |
 | | | VRK3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VRK3 |
|  |  |  | | | | ThermoFisher Antibodies for VRK3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VRK3 |
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