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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

VPS52 Gene

protein-coding GIFtS: 49
GCID: GC06M033218

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

(Previous names: SAC2 suppressor of actin mutations 2-like (yeast), vacuolar...)
(Previous symbol: SACM2L)

7 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)¹ ²		ARE1²
SACM2L¹ ² ³ ⁵		RP5-1033B10²
SAC2 Suppressor Of Actin Mutations 2-Like Protein² ³		SAC2²
SAC2 Suppressor Of Actin Mutations 2-Like (Yeast)¹		dJ1033B10.5²
Vacuolar Protein Sorting 52 (Yeast)¹		Vacuolar Protein Sorting-Associated Protein 52 Homolog²

External Ids:	HGNC: 10518¹	Entrez Gene: 6293²	Ensembl: ENSG00000223501⁷	OMIM: 603443⁵	UniProtKB: Q8N1B4³

Export aliases for VPS52 gene to outside databases

Previous GC identifers: GC06M033210 GC06M033264 GC06M033326 GC06M032960

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VPS52 Gene:

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms

a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from

from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a

head-to-head orientation with the gene encoding ribosomal protein S18. (provided by RefSeq, Jul 2008)

GeneCards Summary for VPS52 Gene:

VPS52 (vacuolar protein sorting 52 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with VPS52 include azoospermia, and macular degeneration. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4

Function: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is

required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this

cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD

Gene Wiki entry for VPS52 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NT_007592.15 NT_113891.2 NT_167245.1 NT_167247.1 NT_167248.1 NT_167249.1 NC_018917.2

NT_167246.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the VPS52 gene promoter:
ER-alpha p53 AP-1 ATF-2 Olf-1 Meis-1b HNF-4alpha1 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VPS52 promoter sequence

Search SABiosciences Chromatin IP Primers for VPS52

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS52

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.32 HGNC cytogenetic band: 6p21.3

VPS52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VPS52 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M033218: view genomic region (about GC identifiers)

Start:	33,218,049 bp from pter	End:	33,239,824 bp from pter
Size:	21,776 bases	Orientation:	minus strand

6 alternative locations:

Chr6-,NT_113891.2 4,661,875-4,683,472	Chr6-,NT_167247 4,691,839-4,713,432	Chr6-,NT_167249 4,698,274-4,719,864
Chr6-,NT_167246 4,675,353-4,677,055	Chr6-,NT_167245 4,499,369-4,520,984	Chr6-,NT_167248 4,450,268-4,471,898

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4 (See protein sequence)

Recommended Name: Vacuolar protein sorting-associated protein 52 homolog

Size: 723 amino acids; 82221 Da

Subunit: Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three)

complex, composed of VPS51, VPS52, VPS53 and VPS54. Interacts with RAB6A and STX10

Subcellular location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane;

Peripheral membrane protein

Sequence caution: Sequence=CAI95619.1; Type=Erroneous gene model prediction;

Secondary accessions: A2BF38 B0UZZ4 Q53GR4 Q5JPA0 Q5SQW1 Q8IUN6 Q9NPT5

Explore the universe of human proteins at neXtProt for VPS52: NX_Q8N1B4

Explore proteomics data for VPS52 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q8N1B4

VPS52 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_072047.4

ENSEMBL proteins:

ENSP00000436612 ENSP00000409952 ENSP00000395282

Human Recombinant Protein Products for VPS52:

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	Cloud-Clone Corp. Proteins for VPS52

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005794	Golgi apparatus	IEA	--
GO:0010008	endosome membrane	IEA	--

VPS52 for ontologies About GeneDecksing

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	Cloud-Clone Corp. ELISAs for VPS52 Cloud-Clone Corp. CLIAs for VPS52

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro protein domain:

IPR007258 Vps52

Graphical View of Domain Structure for InterPro Entry Q8N1B4

ProtoNet protein and cluster: Q8N1B4

UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4

Similarity: Belongs to the VPS52 family

VPS52 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: VPS52_HUMAN, Q8N1B4

Function: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is

required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this

cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--

VPS52 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for VPS52:

Increased gamma-H2AX phosphory

5 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Vps52):

cardiovascular system

embryogenesis

growth/size

mortality/aging

normal

VPS52 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Vps52^tm1.2Kab for VPS52

inGenious Targeting Laboratory - Custom generated mouse model solutions for VPS52

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miRNA Products:
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		hsa-miR-124* hsa-miR-1184 hsa-miR-544 hsa-miR-125a-3p hsa-miR-3613-3p hsa-miR-4255 hsa-miR-1827 hsa-miR-1205

		SwitchGear 3'UTR luciferase reporter plasmid: VPS52 3' UTR sequence

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS52

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for VPS52

5/62 Interacting proteins for VPS52 (Q8N1B4^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 62)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
VPS53	Q5VIR6³	I2D: score=8
ATP6V0D1	P61421³	I2D: score=5
EIF2B2	P49770³	I2D: score=5
SAR1B	Q9Y6B6³	I2D: score=5
SDAD1	Q9NVU7³	I2D: score=5

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0010668	ectodermal cell differentiation	IEA	--
GO:0015031	protein transport	IEA	--
GO:0048611	embryonic ectodermal digestive tract development	IEA	--

VPS52 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for VPS52

Search CenterWatch for drugs/clinical trials and news about VPS52

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for VPS52 gene:

NM_022553.4

Unigene Cluster for VPS52:

Vacuolar protein sorting 52 homolog (S. cerevisiae)

Hs.480356 [show with all ESTs]

Unigene Representative Sequence: AK093057

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000482399(uc003odo.1) ENST00000445902(uc003odm.1 uc011dqz.1)

ENST00000478934(uc003odn.1) ENST00000495981 ENST00000493674 ENST00000471309

ENST00000461743 ENST00000493379 ENST00000495755 ENST00000463486 ENST00000464425

ENST00000436044(uc011dqy.1)

miRNA Products:
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		8 QIAGEN miScript miRNA Assays for microRNAs that regulate VPS52:
		hsa-miR-124* hsa-miR-1184 hsa-miR-544 hsa-miR-125a-3p hsa-miR-3613-3p hsa-miR-4255 hsa-miR-1827 hsa-miR-1205

		SwitchGear 3'UTR luciferase reporter plasmid: VPS52 3' UTR sequence

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS52

Additional mRNA sequence:

AJ006026.1 AK001725.1 AK093057.1 AK222867.1 AK297935.1 AK299563.1 AK300308.1 AK300430.1

AK304080.1 AL390171.1 BC032108.1 BC040114.1

22 DOTS entries:

DT.100657026 DT.100872513 DT.121307939 DT.121307941 DT.100657029 DT.316371 DT.92441544 DT.92060210

DT.121308072 DT.121308068 DT.100688733 DT.95329711 DT.95329720 DT.100657028 DT.121307945 DT.121308017

DT.425507 DT.91696044 DT.95251824 DT.75119863 DT.95149522 DT.96085306

24/325 AceView cDNA sequences (see all 325):

AW292339 BQ228285 AA961126 AI937084 BM705047 AA593405 BQ423280 BI091965

BQ022405 NM_022553 AA972254 NM_080564 AW292560 AW237668 BQ130065 BQ070593

AL134887 BQ889637 BF197439 AA454912 BX378838 CD512140 BI821081 BG680371

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

VPS52 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AAGCCTCCTC

About this image

See VPS52 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VPS52

SOURCE GeneReport for Unigene cluster: Hs.480356

SABiosciences Custom PCR Arrays for VPS52

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS52

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS52

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for VPS52 gene from 9/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Vps52^{1 , 5}	vacuolar protein sorting 52 (yeast)^{1, 5}	88.98(n)¹ 98.2(a)¹		17 (17.98 cM)⁵ 224705¹ NM_172620.3¹ NP_766208.2¹ 33955812⁵
lizard (Anolis carolinensis)	Reptilia	VPS52⁶	Uncharacterized protein	76(a)	1 ↔ 1	GL343857.1(32393-55125)
African clawed frog (Xenopus laevis)	Amphibia	Xl.11507²	Xenopus laevis transcribed sequence with weak similarity more	76.85(n)		BU911662.1
zebrafish (Danio rerio)	Actinopterygii	BM141619.1²	--	76.89(n)		BM141619.1
fruit fly (Drosophila melanogaster)	Insecta	CG7371¹	CG7371	57.01(n) 51.46(a)		33774 NM_135087.2 NP_608931.1
worm (Caenorhabditis elegans)	Secernentea	vps-52¹	Protein VPS-52	46.33(n) 36.01(a)		181018 NM_076881.4 NP_509282.2
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	VPS52¹	Vps52p	38(n) 24.22(a)		852095 NP_010772.1
thale cress (Arabidopsis thaliana)	eudicotyledons	POK¹	Vps52 / Sac2-like protein	48.8(n) 36.08(a)		843468 NM_105796.3 NP_565015.1
rice (Oryza sativa)	Liliopsida	Os03g0417900¹	hypothetical protein	47.42(n) 36.48(a)		4333120 NM_001056907.1 NP_001050372.1

ENSEMBL Gene Tree for VPS52 (if available)
TreeFam Gene Tree for VPS52 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs142445456^1,2	C	--	33223169(+)	`GCCTTA/CATCTC`	1	--	int¹		0	--	--	--	--
rs115100599^1,2	C,F	--	33223188(+)	`ATCCCG/ACCTCA`	1	--	int¹		1		NA	120
rs112508703^1,2	C	--	33223334(+)	`CAAGGC/TGGGCA`	1	--	int¹		1		WA	2
rs418002^1,2	C	--	33223425(-)	`tgcccG/Agtatt`	1	--	int¹		3		NA EA	242
rs213218^1,2	C,F,A,H	--	33223426(+)	`ataccG/Aggcat`	1	--	int¹		9		NS EA WA NA	774
rs407819^1,2	C	--	33223462(-)	`cctccC/Tgagta`	1	--	int¹		0	--	--	--	--
rs12210802^1,2	C,F,H	--	33223622(+)	`aggcaG/Aatccc`	1	--	int¹		8		NS EA NA	1224
rs213219^1,2	C,F,A	--	33223659(+)	`agagaT/Gtctcc`	1	--	int¹		6		NA WA EA	364
rs113105559^1,2	C,F	--	33223979(+)	`AGACTC/ATCTTA`	1	--	int¹		3		CSA WA	122
rs200321514^1,2		--	33224085(+)	`TACAG-/AAAAAA`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for VPS52 (33218049 - 33239824 bp)

Structural Variations
Database of Genomic Variants (DGV) 3 variations for VPS52: About this table

Variant ID	Type	Subtype	PubMed ID
nsv830634	CNV	Loss	17160897
nsv830635	CNV	Loss	17160897
nsv5249	CNV	Loss	18451855

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VPS52

DNA2.0 Custom Variant and Variant Library Synthesis for VPS52

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

VPS52 for disorders           About GeneDecksing

OMIM gene information: 603443    OMIM disorders: --

7 diseases for VPS52:    About MalaCards

azoospermia macular degeneration ataxia systemic lupus erythematosus

lupus erythematosus prostate cancer prostatitis

Genetic Association Database (GAD): VPS52
Human Genome Epidemiology (HuGE) Navigator: VPS52 (4 documents)

Export disorders for VPS52 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for VPS52 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with VPS52)

Utopia: connect your pdf to the dynamic
world of online information

Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex. (PubMed id 9790748)^{1, 3, 9} Walter L. and Guenther E. (1998)
Ang2/fat-free is a conserved subunit of the Golgi-ass ociated retrograde protein complex. (PubMed id 20685960)^{1, 2} PAcrez-Victoria F.J....Bonifacino J.S. (2010)
High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)^{1, 4} Barcellos L.F....Criswell L.A. (2009)
Requirement of the Human GARP Complex for Mannose 6-phosphate- receptor-dependent Sorting of Cathepsin D to Lysosomes. (PubMed id 18367545)^{1, 2} Perez-Victoria F.J.... Bonifacino J.S. (2008)
Characterization of the human GARP (Golgi associated retrograde protein) complex. (PubMed id 15878329)^{1, 2} Liewen H.... Stenner-Liewen F. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Susceptibility locus for non-obstructive azoospermia is localized within the HLA-DR/DQ subregion: primary role of DQB1*0604. (PubMed id 12366783)^{1, 4} Matsuzaka Y....Inoko H. (2002)
Linkage between polymorphisms in the prostate specific antigen ARE1 gene region, prostate cancer risk, and circulating tumor cells. (PubMed id 12210484)^{1, 4} Medeiros R....Lopes C. (2002)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 6293	HGNC: 10518	AceView: VPS52	Ensembl:ENSG00000223501	euGenes: HUgn6293
ECgene: VPS52	H-InvDB: VPS52

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for VPS52	Pharmacogenomics, SNPs, Pathways

Intellectual Property for VPS52 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for VPS52 gene:
Search GeneIP for patents involving VPS52

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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VPS52 Gene

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

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VPS52 Gene

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

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