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VPS52 Gene

protein-coding GIFtS: 50
GCID: GC06M033218

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

(Previous names: SAC2 suppressor of actin mutations 2-like (yeast), vacuolar...)
(Previous symbol: SACM2L)

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)¹ ²		ARE1²
SACM2L¹ ² ³ ⁵		SAC2²
SAC2 Suppressor Of Actin Mutations 2-Like Protein² ³		dJ1033B10.5²
SAC2 Suppressor Of Actin Mutations 2-Like (Yeast)¹		Vacuolar Protein Sorting-Associated Protein 52 Homolog²
Vacuolar Protein Sorting 52 (Yeast)¹

External Ids:	HGNC: 10518¹	Entrez Gene: 6293²	Ensembl: ENSG00000223501⁷	OMIM: 603443⁵	UniProtKB: Q8N1B4³

Export aliases for VPS52 gene to outside databases

Previous GC identifers: GC06M033210 GC06M033264 GC06M033326 GC06M032960

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VPS52 Gene:

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein

forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle

trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on

chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing

results in multiple transcript variants. (provided by RefSeq, Jan 2014)

GeneCards Summary for VPS52 Gene:

VPS52 (vacuolar protein sorting 52 homolog (S. cerevisiae)) is a protein-coding gene.

UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4

Function: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex

is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes,

this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD

Gene Wiki entry for VPS52 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000006.11 NT_007592.16 NT_113891.3 NT_167245.2 NT_167247.2 NT_167248.2 NT_167249.2 NC_018917.2

NT_167246.2

Regulatory elements:

Regulatory transcription factor binding sites in the VPS52 gene promoter:
ER-alpha p53 AP-1 ATF-2 Olf-1 Meis-1b HNF-4alpha1 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VPS52 promoter sequence

Search Chromatin IP Primers for VPS52

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VPS52

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.32 HGNC cytogenetic band: 6p21.3

VPS52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VPS52 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M033218: view genomic region (about GC identifiers)

Start:	33,218,049 bp from pter	End:	33,239,824 bp from pter
Size:	21,776 bases	Orientation:	minus strand

6 alternative locations:

Chr6-,NT_167249 4,698,274-4,719,864	Chr6-,NT_167245 4,499,369-4,520,984	Chr6-,NT_167247 4,691,839-4,713,432
Chr6-,NT_167248 4,450,268-4,471,898	Chr6-,NT_113891.2 4,661,875-4,683,472	Chr6-,NT_167246 4,675,353-4,677,055

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4 (See protein sequence)

Recommended Name: Vacuolar protein sorting-associated protein 52 homolog

Size: 723 amino acids; 82221 Da

Subunit: Component of the Golgi-associated retrograde protein (GARP) complex, also called VFT (VPS fifty-three)

complex, composed of VPS51, VPS52, VPS53 and VPS54. Interacts with RAB6A and STX10

Sequence caution: Sequence=CAI95619.1; Type=Erroneous gene model prediction;

Secondary accessions: A2BF38 B0UZZ4 Q53GR4 Q5JPA0 Q5SQW1 Q8IUN6 Q9NPT5

Explore the universe of human proteins at neXtProt for VPS52: NX_Q8N1B4

Explore proteomics data for VPS52 at MOPED

Post-translational modifications:

Ubiquitination² at Lys205

Modification sites at PhosphoSitePlus

See VPS52 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts):

NP_001276103.1 NP_001276104.1 NP_001276105.1 NP_072047.4

ENSEMBL proteins:

ENSP00000436612 ENSP00000409952 ENSP00000395282

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:

IPR007258 Vps52

Graphical View of Domain Structure for InterPro Entry Q8N1B4

ProtoNet protein and cluster: Q8N1B4

UniProtKB/Swiss-Prot: VPS52_HUMAN, Q8N1B4

Similarity: Belongs to the VPS52 family

Find genes that share domains with VPS52 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: VPS52_HUMAN, Q8N1B4

Function: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex

is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes,

this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	18985028

Find genes that share ontologies with VPS52 About GenesLikeMe

Phenotypes:
1 GenomeRNAi human phenotype for VPS52:

Increased gamma-H2AX phosphory

5 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Vps52):

cardiovascular system

embryogenesis

growth/size/body

mortality/aging

normal

Find genes that share phenotypes with VPS52 About GenesLikeMe

Animal Models:
MGI mouse knock-out Vps52^tm1.2Kab for VPS52

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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

VPS52_HUMAN, Q8N1B4: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome

membrane; Peripheral membrane protein

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
endosome	5
golgi apparatus	3
cytosol	1
peroxisome	1

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Gene Ontology (GO): 2 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005794	Golgi apparatus	IEA	--
GO:0010008	endosome membrane	IEA	--

Find genes that share ontologies with VPS52 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for VPS52
Interactions:

GeneGlobe Interaction Network for VPS52

STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

Selected Interacting proteins for VPS52 (Q8N1B4^{2, 3} ENSP00000409952⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 78)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COG3	Q96JB2³, ENSP00000258654⁴	I2D: score=4 STRING: ENSP00000258654
RAB6B	Q9NRW1³, ENSP00000285208⁴	I2D: score=2 STRING: ENSP00000285208
TMEM30B	Q3MIR4³, ENSP00000347930⁴	I2D: score=1 STRING: ENSP00000347930
RAB6A	P20340³, ENSP00000311449⁴	I2D: score=2 STRING: ENSP00000311449
SC5D	O75845³, ENSP00000264027⁴	I2D: score=1 STRING: ENSP00000264027

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Gene Ontology (GO): 3 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0010668	ectodermal cell differentiation	IEA	--
GO:0015031	protein transport	IEA	--
GO:0048611	embryonic ectodermal digestive tract development	IEA	--

Find genes that share ontologies with VPS52 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

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Browse compounds at ApexBio

Browse Tocris compounds for VPS52

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for VPS52 gene (4 alternative transcripts):

NM_001289174.1 NM_001289175.1 NM_001289176.1 NM_022553.5

Unigene Cluster for VPS52:

Vacuolar protein sorting 52 homolog (S. cerevisiae)

Hs.480356 [show with all ESTs]

Unigene Representative Sequence: AK093057

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000482399(uc003odo.1) ENST00000445902(uc003odm.1 uc011dqz.1)

ENST00000478934(uc003odn.1) ENST00000495981 ENST00000493674 ENST00000471309

ENST00000461743 ENST00000493379 ENST00000495755 ENST00000463486 ENST00000464425

ENST00000436044(uc011dqy.1)

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		QuantiFast Probe-based Assays in human, mouse, rat VPS52

Additional mRNA sequence:

AJ006026.1 AK001725.1 AK093057.1 AK222867.1 AK297935.1 AK299563.1 AK300308.1 AK300430.1

AK304080.1 AL390171.1 BC032108.1 BC040114.1

22 DOTS entries:

DT.100657026 DT.100872513 DT.121307939 DT.121307941 DT.100657029 DT.316371 DT.92441544 DT.92060210

DT.121308072 DT.121308068 DT.100688733 DT.95329711 DT.95329720 DT.100657028 DT.121307945 DT.121308017

DT.425507 DT.91696044 DT.95251824 DT.75119863 DT.95149522 DT.96085306

Selected AceView cDNA sequences (see all 325):

BM272572 BC040114 AW247815 AI754310 BQ941334 AK093057 AW439761 AA593405

AL559461 CD107070 AW237668 BG680371 BQ067673 AA454912 CD558898 BC032108

AI434054 CB250483 BG231907 AW292560 AA961126 CD512140 BG260938 AU133227

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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VPS52 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: AAGCCTCCTC

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VPS52 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

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VPS52 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.480356

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for VPS52 gene from Selected species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Vps52^{1 , 5}	vacuolar protein sorting 52 (yeast)^{1, 5}	88.92(n)¹ 98.61(a)¹		17 (17.98 cM)⁵ 224705¹ NM_172620.3¹ NP_766208.2¹ 33955812⁵
lizard (Anolis carolinensis)	Reptilia	VPS52⁶	vacuolar protein sorting 52 homolog (S. cerevisiae...	76(a)	1 ↔ 1	GL343857.1(32393-55125)
African clawed frog (Xenopus laevis)	Amphibia	Xl.11507²	Xenopus laevis transcribed sequence with weak similarity more	76.85(n)		BU911662.1
zebrafish (Danio rerio)	Actinopterygii	BM141619.1²	--	76.89(n)		BM141619.1
fruit fly (Drosophila melanogaster)	Insecta	CG7371¹	CG7371	57.18(n) 51.73(a)		33774 NM_135087.2 NP_608931.1
worm (Caenorhabditis elegans)	Secernentea	vps-52¹	vps-52	46.75(n) 36.69(a)		181018 NM_076881.5 NP_509282.3
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	VPS52⁶	Component of the GARP (Golgi-associated retrograde...	19(a)	1 ↔ 1	IV(1422763-1424688) YDR484W
thale cress (Arabidopsis thaliana)	eudicotyledons	POK¹	POK	49.34(n) 36.69(a)		843468 NM_105796.3 NP_565015.1
rice (Oryza sativa)	Liliopsida	Os03g0417900¹	Os03g0417900	47.51(n) 36.85(a)		4333120 NM_001056907.1 NP_001050372.1

ENSEMBL Gene Tree for VPS52 (if available)
TreeFam Gene Tree for VPS52 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs142445456^1,2	C	--	33223169(+)	`GCCTTA/CATCTC`	1	--	int¹		0	--	--	--	--
rs115100599^1,2	C,F	--	33223188(+)	`ATCCCG/ACCTCA`	1	--	int¹		1		NA	120
rs112508703^1,2	C	--	33223334(+)	`CAAGGC/TGGGCA`	1	--	int¹		1		WA	2
rs418002^1,2	C	--	33223425(-)	`tgcccG/Agtatt`	1	--	int¹		3		NA EA	242
rs213218^1,2	C,F,A,H	--	33223426(+)	`ataccG/Aggcat`	1	--	int¹		9		NS EA WA NA	774
rs407819^1,2	C	--	33223462(-)	`cctccC/Tgagta`	1	--	int¹		0	--	--	--	--
rs12210802^1,2	C,F,H	--	33223622(+)	`aggcaG/Aatccc`	1	--	int¹		8		NS EA NA	1224
rs213219^1,2	C,F,A	--	33223659(+)	`agagaT/Gtctcc`	1	--	int¹		6		NA WA EA	364
rs113105559^1,2	C,F	--	33223979(+)	`AGACTC/ATCTTA`	1	--	int¹		3		CSA WA	122
rs200321514^1,2		--	33224085(+)	`TACAG-/AAAAAA`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for VPS52 (33218049 - 33239824 bp)

Structural Variations
Database of Genomic Variants (DGV) 3 variations for VPS52: About this table

Variant ID	Type	Subtype	PubMed ID
nsv830634	CNV	Loss	17160897
nsv830635	CNV	Loss	17160897
nsv5249	CNV	Loss	18451855

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing VPS52

DNA2.0 Custom Variant and Variant Library Synthesis for VPS52

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 603443 OMIM disorders: --

Find genes that share disorders with VPS52 About GenesLikeMe

Genetic Association Database (GAD): VPS52
Human Genome Epidemiology (HuGE) Navigator: VPS52 (4 documents)

Export disorders for VPS52 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for VPS52 gene, integrated from 10 sources (see all 24):
(articles sorted by number of sources associating them with VPS52)

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Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex. (PubMed id 9790748)^{1, 3, 9} Walter L. and Guenther E. (Genomics 1998)
Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex. (PubMed id 20685960)^{1, 2} Perez-Victoria F.J.... Bonifacino J.S. (Mol. Biol. Cell 2010)
High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)^{1, 4} Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
Requirement of the human GARP complex for mannose 6-phosphate- receptor-dependent sorting of cathepsin D to lysosomes. (PubMed id 18367545)^{1, 2} Perez-Victoria F.J.... Bonifacino J.S. (Mol. Biol. Cell 2008)
Characterization of the human GARP (Golgi associated retrograde protein) complex. (PubMed id 15878329)^{1, 2} Liewen H.... Stenner-Liewen F. (Exp. Cell Res. 2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (Nature 2003)
Susceptibility locus for non-obstructive azoospermia is localized within the HLA-DR/DQ subregion: primary role of DQB1*0604. (PubMed id 12366783)^{1, 4} Matsuzaka Y....Inoko H. (Tissue Antigens 2002)
Linkage between polymorphisms in the prostate specific antigen ARE1 gene region, prostate cancer risk, and circulating tumor cells. (PubMed id 12210484)^{1, 4} Medeiros R....Lopes C. (Prostate 2002)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (Cell 2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 6293	HGNC: 10518	AceView: VPS52	Ensembl:ENSG00000223501	euGenes: HUgn6293
ECgene: VPS52	H-InvDB: VPS52

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for VPS52	Pharmacogenomics, SNPs, Pathways

Intellectual Property for VPS52 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for VPS52 gene:
Search GeneIP for patents involving VPS52

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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VPS52 Gene

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

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VPS52 Gene

Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae)

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