VPS45 Gene
protein-coding GIFtS: 56
GCID: GC01P150039
|
|
vacuolar protein sorting 45 homolog (S. cerevisiae)(Previous names: vacuolar protein sorting 45A (yeast homolog), vacuolar...)
(Previous symbols: VPS45B, VPS45A)
| |
Aliases
for VPS45 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Vacuolar Protein Sorting 45 Homolog (S. Cerevisiae)1 2 | | H1VPS452 | | VPS45A1 2 3 5 | | VPS54A2 | | VPS45B1 2 3 | | VSP452 | | H11 2 | | VSP45A2 | | HlVps451 | | Leucocyte Vacuolar Protein Sorting 452 | | H-Vps451 | | Vacuolar Protein Sorting 45A2 | | Vacuolar Protein Sorting 45A (Yeast Homolog)1 | | Vacuolar Protein Sorting-Associated Protein 452 | | Vacuolar Protein Sorting 45A (Yeast)1 | | H-VPS451 |
Export aliases for VPS45 gene to outside databasesPrevious GC identifers: GC01P148306 GC01P121419 |
Summaries
for VPS45 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for VPS45:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinctorganelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved invesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequencesimilarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression inperipheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: VPS45_HUMAN, Q9NRW7Function: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network
Gene Wiki entry for VPS45
|
Genomic Views
for VPS45 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the VPS45 gene promoter:
Nkx3-1 Nkx3-1 v4 Brachyury Nkx3-1 v1 STAT5A IRF-1 Nkx3-1 v2 Nkx3-1 v3 LHX3a/Lhx3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for VPS45
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS45 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.2VPS45 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P150039: view genomic region
(about GC identifiers)
Start:
|
150,039,342 bp from pter |
End:
|
150,117,505 bp from pter |
Size:
|
78,164 bases |
Orientation:
|
plus strand |
|
Proteins
for VPS45 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VPS45_HUMAN, Q9NRW7 (See
protein sequence)Recommended Name: Vacuolar protein sorting-associated protein 45 Size: 570 amino acids; 65077 Da
Subunit: Interacts with STX6 (By similarity). Interacts with ZFYVE20
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein (By similarity). Endosome membrane;Peripheral membrane protein (By similarity). Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network(By similarity)
Secondary accessions: D3DUZ9 Q15715 Q5T4P6 Q9Y4Z6Explore the universe of human proteins at neXtProt for VPS45: NX_Q9NRW7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRW7
VPS45 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_009190.2
ENSEMBL proteins: ENSP00000358126 ENSP00000400143 ENSP00000440690 ENSP00000358124 Reactome Protein details: Q9NRW7
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
VPS45 for ontologies About GeneDecksing
VPS45 Antibody Products:
Assay Products for VPS45: |
Protein
Domains /
Families
for VPS45 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VPS45 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NRW7ProtoNet protein and cluster: Q9NRW7 1 Blocks protein family: IPB001619 Sec1-like protein
UniProtKB/Swiss-Prot: VPS45_HUMAN, Q9NRW7Similarity: Belongs to the STXBP/unc-18/SEC1 family |
Function
for VPS45 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VPS45_HUMAN, Q9NRW7Function: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: VPS45 (NM_007259) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VPS45 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS45 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS45 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0005515 | protein binding |
-- | -- |
VPS45 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for VPS45:
|
Pathways & Interactions
for VPS45 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Normal wtCFTR traffic / Sorting endosome formation | | | 2 | Factors involved in megakaryocyte development and platelet production | | | 3 | Endocytosis | | | 4 | Clathrin-dependent protein traffic | | | 5 | Platelet activation, signaling and aggregation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  GeneGo (Thomson Reuters) Pathways for VPS45
2 
Reactome Pathways for VPS45
1 
Kegg Pathway (Kegg details for VPS45):
VPS45 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VPS45
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/52 Interacting proteins for VPS45 (Q9NRW73 ENSP000003581264) via UniProtKB, MINT, STRING, and/or I2D (see all 52)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
VPS45 for ontologies About GeneDecksing
|
Drugs & Compounds
for VPS45 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VPS45
Search CenterWatch for drugs/clinical trials and news about VPS45
|
Transcripts
for VPS45 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VPS45 gene: NM_007259.3 Unigene Cluster for VPS45: Vacuolar protein sorting 45 homolog (S. cerevisiae) Hs.443750 [show with all ESTs]Unigene Representative Sequence: NM_00725912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369130(uc010pbr.1 uc009wlm.1 uc010pbp.1 uc001etp.3 uc010pbq.2 uc001etq.3)
ENST00000462852 ENST00000478999 ENST00000460366 ENST00000497638 ENST00000419023
ENST00000477558 ENST00000472756 ENST00000491789 ENST00000484306 ENST00000535106
ENST00000369128(uc010pbs.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: VPS45 (NM_007259) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VPS45 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS45 |
Additional cDNA sequence: AF165513.1 AJ133421.1 AK023170.1 AK223214.1 AK293555.1 AK295529.1 AK298786.1 AK298835.1 AK301994.1 AK307949.1 AY453586.1 BC012932.1 BC028382.2 19 DOTS entries: DT.447459 DT.95284029 DT.95194412 DT.100803657 DT.75164560 DT.95194417 DT.95239400 DT.121414882 DT.416990 DT.97845520 DT.99988117 DT.40113939 DT.92463595 DT.95194400 DT.95194413 DT.100803655 DT.40132558 DT.92463612 DT.95194414 24/253 AceView cDNA sequences (see all 253): AU131412 AA291962 BC028382 N50867 AI057492 BQ001991 BM454221 BM563489 BM681711 BU528438 BM724061 AA099573 AA809510 AW117623 AA738488 NM_007259 AA902761 BI489999 BE855917 H98649 BQ951312 AA765898 CB159551 BM708815
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for VPS45 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | - | | | | | | - | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | | | - | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b |
|---|
|
| SP1: | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for VPS45
|
Expression
for VPS45 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VPS45 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATGACCACA
About this image
See VPS45 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VPS45
SOURCE GeneReport for Unigene cluster: Hs.443750
UniProtKB/Swiss-Prot: VPS45_HUMAN, Q9NRW7Tissue specificity: Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen,prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheralblood leukocytes and liver
SABiosciences Expression via Pathway-Focused PCR Array including VPS45:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VPS45
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VPS45 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VPS45 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS45 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS45 |
Orthologs
for VPS45 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for VPS45 gene from 9/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
VPS451 |
vacuolar protein sorting 45 homolog (S. cerevisiae) |
79.89(n)
92.39(a) |
|
430741 NM_001031593.1 NP_001026764.1 |
lizard
(Anolis carolinensis) |
Reptilia |
VPS456 |
-- |
91(a) |
1 ↔ 1 |
GL345017.1(598-10330) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.87032 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.17(n) |
|
BU912999.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.158742 |
Transcribed sequence with moderate similarity to protein more |
75.23(n) |
|
57089617 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Vps451 |
Vacuolar protein sorting 45 |
56.66(n)
55.52(a) |
|
41153 NM_141652.1 NP_649909.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
vps-451 |
Protein VPS-45 |
51.54(n)
48.96(a) |
|
180449 NM_171622.3 NP_741714.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
VPS45(YGL095C)4
VPS451 |
Protein of the Sec1p/Munc-18 family, essential for more4
Vps45p1 |
49.07(n)1
39.88(a)1 |
|
7(330607-328874)4
8527851, 4 NP_011420.31 NP_011420.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
VPS451 |
vacuolar protein sorting-associated protein 45-like more |
52.6(n)
47.1(a) |
|
844050 NM_106364.1 NP_565150.1 |
rice
(Oryza sativa) |
Liliopsida |
AK066001.12 |
-- |
77.44(n) |
|
AK066001.1 |
ENSEMBL Gene Tree for VPS45 (if available)
TreeFam Gene Tree for VPS45 (if available) |
Paralogs
for VPS45 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for VPS45 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VPS45 (150039342 - 150117505 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for VPS45
1 CNV: 97505
1 Indel: 44449 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VPS45 |
|
Disorders
/ Diseases
for VPS45 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
VPS45 for disorders About GeneDecksing
OMIM gene information: 610035
OMIM disorders: --
2  diseases for VPS45: About MalaCardsmalaria prostatitis
Export disorders for VPS45 gene to outside databases
|
Publications
for VPS45 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VPS45 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with VPS45) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking. (PubMed id 8996080)1, 2, 3 Pevsner J.... Scheller R.H. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes. (PubMed id 11788822)1, 2 de Renzis S.... Zerial M. (2002)
- Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain. (PubMed id 11062261)1, 2 Nielsen E.... Zerial M. (2000)
- Molecular cloning and characterization of a cDNA encoding the human leucocyte vacuolar protein sorting (hlVps45). (PubMed id 10404641)1, 2 Rajasekariah P.... Sutherland G.R. (1999)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
|
External Searches for VPS45 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VPS45 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VPS45 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VPS45 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for VPS45 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for VPS45 gene:
Search GeneIP for patents involving VPS45
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VPS45 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for VPS45 | | OriGene shRNA RFP for VPS45 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VPS45 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VPS45 | | | OriGene Protein Over-expression Lysate for VPS45 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VPS45 | | OriGene 3'-UTR Clone for VPS45 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS45 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for VPS45 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VPS45 | | OriGene Custom Protein Services for VPS45 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VPS45 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VPS45 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS45 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VPS45 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS45 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VPS45 |
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| | | | Search Tocris compounds for VPS45 |
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 | | | VPS45 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS45 |
|  |  |  | | | | ThermoFisher Antibodies for VPS45 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS45 |
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