Aliases for VPS33A Gene
External Ids for VPS33A Gene
Previous GeneCards Identifiers for VPS33A Gene
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008]
GeneCards Summary for VPS33A Gene
VPS33A (Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae)) is a Protein Coding gene. An important paralog of this gene is VPS33B.
UniProtKB/Swiss-Prot for VPS33A Gene
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.