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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VPS29 Gene

protein-coding   GIFtS: 56
GCID: GC12M110929

Vacuolar Protein Sorting 29 Homolog (S. Cerevisiae)

(Previous names: vacuolar protein sorting 29 (yeast homolog), vacuolar protein...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Vacuolar Protein Sorting 29 Homolog (S. Cerevisiae)1 2     DC152
Vesicle Protein Sorting 292 3     PEP112
hVPS292 3     Retromer Protein2
PEP11 Homolog2 3     Vacuolar Protein Sorting-Associated Protein 292
EC 3.1.3.33 8     Vacuolar Sorting Protein VPS29/PEP112
Vacuolar Protein Sorting 29 (Yeast Homolog)1     X 007 Protein2
Vacuolar Protein Sorting 29 (Yeast)1     

External Ids:    HGNC: 143401   Entrez Gene: 516992   Ensembl: ENSG000001112377   OMIM: 6069325   UniProtKB: Q9UBQ03   

Export aliases for VPS29 gene to outside databases

Previous GC identifers: GC12M109953 GC12M110725 GC12M110771 GC12M109341 GC12M109392 GC12M107947


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VPS29 Gene:
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the
efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric
complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the
trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat
for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different
isoforms and representing non-protein coding transcripts have been found for this gene. (provided by RefSeq, Aug
2013)

GeneCards Summary for VPS29 Gene: 
VPS29 (vacuolar protein sorting 29 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with VPS29 include paraplegia, and down syndrome, and among its related super-pathways are Asparagine N-linked glycosylation and Signaling by GPCR. GO annotations related to this gene include phosphoserine phosphatase activity and metal ion binding.

UniProtKB/Swiss-Prot: VPS29_HUMAN, Q9UBQ0
Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors
(IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the
polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a
serine-phosphorylated peptide derived from IGF2R (in vitro)

Gene Wiki entry for VPS29 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009775.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VPS29 gene promoter:
         GR   AML1a   GATA-1   Evi-1   AREB6   Egr-2   FOXJ2 (long isoform)   GR-alpha   FOXJ2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVPS29 promoter sequence
   Search SABiosciences Chromatin IP Primers for VPS29

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS29


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24   Ensembl cytogenetic band:  12q24.11   HGNC cytogenetic band: 12q24

VPS29 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VPS29 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M110929:  view genomic region     (about GC identifiers)

Start:
110,928,902 bp from pter      End:
110,939,922 bp from pter
Size:
11,021 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VPS29_HUMAN, Q9UBQ0 (See protein sequence)
Recommended Name: Vacuolar protein sorting-associated protein 29  
Size: 182 amino acids; 20506 Da
Cofactor: Binds 2 zinc ions per subunit (Probable)
Subunit: Component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2.
Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane
protein (By similarity)
2 PDB 3D structures from and Proteopedia for VPS29:
1W24 (3D)        2R17 (3D)    
Secondary accessions: Q502Y5 Q6FIF8 Q6IAH3 Q9H0W0 Q9NRP1 Q9NRU7
Alternative splicing: 2 isoforms:  Q9UBQ0-1   Q9UBQ0-2   

Explore the universe of human proteins at neXtProt for VPS29: NX_Q9UBQ0

Explore proteomics data for VPS29 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UBQ0

  • 4/6 DME Specific Peptides for VPS29 (Q9UBQ0) (see all 6)
     FKKLLVP  DVHIVRGD  NPGSATGA  DVDILISGHT 

    VPS29 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    VPS29 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001269079.1  NP_001269080.1  NP_057310.1  NP_476528.1  

    ENSEMBL proteins: 
     ENSP00000447058   ENSP00000353786   ENSP00000449954   ENSP00000449044   ENSP00000447634  
     ENSP00000400048  
    Reactome Protein details: Q9UBQ0
    Human Recombinant Protein Products for VPS29: 
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    Cloud-Clone Corp. Proteins for VPS29 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IDA--
    GO:0005829cytosol TAS--
    GO:0010008endosome membrane IEA--

    VPS29 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR024654 Calcineurin-like_PEstase_dom
     IPR000979 Phosphodiesterase_MJ0936

    Graphical View of Domain Structure for InterPro Entry Q9UBQ0

    ProtoNet protein and cluster: Q9UBQ0

    1 Blocks protein domain: IPB000979 Protein of unknown function UPF0025

    UniProtKB/Swiss-Prot: VPS29_HUMAN, Q9UBQ0
    Similarity: Belongs to the VPS29 family


    VPS29 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VPS29_HUMAN, Q9UBQ0
    Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors
    (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the
    polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a
    serine-phosphorylated peptide derived from IGF2R (in vitro)
    Catalytic activity: O-phospho-L(or D)-serine + H(2)O = L(or D)-serine + phosphate

         Enzyme Number (IUBMB): EC 3.1.3.31 2

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004647phosphoserine phosphatase activity IEA--
    GO:0016788hydrolase activity, acting on ester bonds ----
    GO:0046872metal ion binding IEA--
         
    VPS29 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for VPS29:
     Decreased cilium length after  

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for VPS29 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Asparagine N-linked glycosylation
    WNT ligand biogenesis and trafficking0.77
    Signaling by Wnt0.62
    2Signaling by GPCR
    Signal Transduction0.55

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for VPS29
        Signaling by Wnt
    Signal Transduction
    WNT ligand biogenesis and trafficking



    VPS29 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VPS29

    5/63 Interacting proteins for VPS29 (Q9UBQ02, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 63)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RGS2P412202, 3MINT-63737 MINT-8268977 I2D: score=5 
    FRA10AC1Q70Z532, 3MINT-64742 I2D: score=4 
    CNOT10Q9H9A53I2D: score=5 
    CTR9Q6PD623I2D: score=5 
    VPS26BQ4G0F53I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--

    VPS29 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VPS29

    Search CenterWatch for drugs/clinical trials and news about VPS29

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for VPS29 gene (4 alternative transcripts): 
    NM_001282150.1  NM_001282151.1  NM_016226.4  NM_057180.2  

    Unigene Cluster for VPS29:

    Vacuolar protein sorting 29 homolog (S. cerevisiae)
    Hs.600114  [show with all ESTs]
    Unigene Representative Sequence: AL832866
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000549578(uc001tqy.3 uc001tqz.3) ENST00000360579 ENST00000552130(uc001tqw.3)
    ENST00000546588 ENST00000548539 ENST00000549970 ENST00000548259 ENST00000553128
    ENST00000551655 ENST00000550267 ENST00000447578
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate VPS29:
    hsa-miR-548t
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    Inhib. RNA
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    Additional mRNA sequence: 

    AB578890.1 AB578891.1 AB578892.1 AB618733.1 AF168716.1 AF175264.1 AF193795.1 AF201936.1 
    AF201946.1 AK000499.1 AK129767.1 AL136614.1 AL832866.1 BC000880.1 BC015095.1 BC017964.1 
    BC032462.1 BC095446.1 CR457182.1 CR533468.1 

    24/33 DOTS entries (see all 33):

    DT.100030621  DT.92454726  DT.95159343  DT.100693387  DT.99983727  DT.100798252  DT.99998055  DT.121216149 
    DT.100798246  DT.87015428  DT.121216063  DT.100030625  DT.91869808  DT.75185056  DT.121216079  DT.121216214 
    DT.121216061  DT.121216153  DT.92454730  DT.100030626  DT.121216291  DT.95159356  DT.95251589  DT.100798245 

    24/538 AceView cDNA sequences (see all 538):

    AI926100 BQ012751 BQ008168 AW022758 AA662929 BM664339 BQ011727 AA411461 
    CR594493 BG260117 BE349072 CN480615 BM698718 BU659680 AA360727 BM981748 
    BQ027237 CF455280 N91595 AK000499 AF193795 BU683261 AA912469 AW161052 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for VPS29 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c ^ 8a · 8b
    SP1:                          -     -     -     -     -     -                             -               
    SP2:                          -           -     -     -     -                             -               
    SP3:                    -     -     -     -     -     -     -                             -               
    SP4:                    -     -     -     -     -     -     -                                             
    SP5:                    -     -     -                                                                     


    ECgene alternative splicing isoforms for VPS29

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VPS29 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    VPS29 Expression
    About this image


    See VPS29 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VPS29

    SOURCE GeneReport for Unigene cluster: Hs.600114

    UniProtKB/Swiss-Prot: VPS29_HUMAN, Q9UBQ0
    Tissue specificity: Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes,
    thymus, colon skeletal muscle, kidney and brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for VPS29 gene from 10/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vps291 , 5 vacuolar protein sorting 29 (S. pombe)1, 5 90.19(n)1
    100(a)1
      5 (62.32 cM)5
    564331  NM_019780.11  NP_062754.11 
     1223543695 
    chicken
    (Gallus gallus)
    Aves VPS291 vacuolar protein sorting 29 homolog (S. cerevisiae) 85.41(n)
    97.3(a)
      416867  NM_001007837.1  NP_001007838.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    97(a)
    90(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    GL343423.1(308248-318192)
    GL343588.1(147296-147856)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG409918.12   -- 82.7(n)    BG409918.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb06g052 wufb06g05 79.26(n)   336820  BC045981.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG47641 , 3 CG47641 83(a)3
    70.93(n)1
    83.89(a)1
      21F23
    332951  NM_134731.21  NP_608575.11 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK1128.83
    vps-291
    Protein VPS-291 60(a)3
    60.72(n)1
    58.92(a)1
      III(10183817-10184985)3
    1764241  NM_001027817.11  NP_001022988.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS29(YHR012W)4
    VPS291
    Endosomal protein that is a subunit of the membrane-associated more4
    Vps29p1
    52.07(n)1
    49.64(a)1
      8(129481-130448)4
    8564031, 4  NP_011876.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons MAG11 vacuolar protein sorting 29 protein 62.06(n)
    65.75(a)
      823935  NM_114649.4  NP_190365.3 
    rice
    (Oryza sativa)
    Liliopsida Os.101982 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.19(n)    AK060027.1 


    ENSEMBL Gene Tree for VPS29 (if available)
    TreeFam Gene Tree for VPS29 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for VPS29 gene
    2 SIMAP similar genes for VPS29 using alignment to 4 protein entries:     VPS29_HUMAN (see all proteins):
    DKFZp667O202    vps29

    VPS29 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/143 SNPs in VPS29 are shown (see all 143)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1850568471,2
    --110928838(+) CGTTAC/TATATT 2 -- ds50010--------
    rs1454305581,2
    --110928951(+) GTGATC/TTCGGC 2 -- ds50010--------
    rs1492055881,2
    --110929011(+) TCCCGA/GGTAGC 2 -- ds50010--------
    rs47664921,2
    C,F,A,H--110929261(+) AATGTC/TGGCAT 2 -- ds500137Minor allele frequency- N:0.00NS EA NA WA 3278
    rs1468169121,2
    C--110929331(+) GCTCTA/GAAAGG 2 -- ut310--------
    rs1899345211,2
    --110929399(+) GTTTTG/TTTTTA 2 -- ut310--------
    rs751529211,2
    C,F--110929456(+) TACTGG/AAGAAG 2 -- ut311Minor allele frequency- A:0.02NA 120
    rs1998058271,2
    --110929959(+) TGTTTC/TGTAGC 2 -- int10--------
    rs1931844751,2
    --110929978(+) GCAGCA/GCTATA 2 -- int10--------
    rs1854507131,2
    --110930152(+) GGTGGA/GTCACC 2 -- int10--------

    HapMap Linkage Disequilibrium report for VPS29 (110928902 - 110939922 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for VPS29:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv826512CNV Loss20364138

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606932    OMIM disorders: --

    2 diseases for VPS29:    About MalaCards
    paraplegia    down syndrome


    VPS29 for disorders           About GeneDecksing


    Export disorders for VPS29 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VPS29 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with VPS29)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human homologues of yeast vacuolar protein sorting 29 and 35. (PubMed id 11062004)1, 2, 3, 9 Edgar A.J. and Polak J.M. (2000)
    2. The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide. (PubMed id 16737443)1, 2, 9 Damen E.... van Leeuwen J.E.M. (2006)
    3. Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites. (PubMed id 15788412)1, 2, 9 Wang D.... Liu P. (2005)
    4. Functional architecture of the retromer cargo-recognition complex. (PubMed id 17891154)1, 2 Hierro A.... Hurley J.H. (2007)
    5. The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. (PubMed id 15247922)1, 2 Verges M.... Mostov K.E. (2004)
    6. Exportin 7 defines a novel general nuclear export pathway. (PubMed id 15282546)1, 2 Mingot J.-M.... Goerlich D. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    9. Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. (PubMed id 11102511)1, 2 Renfrew Haft C.... Taylor S.I. (2000)
    10. Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP T BC1D5. (PubMed id 19531583)1, 9 Seaman M.N....Bright N. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51699 HGNC: 14340 AceView: VPS29 Ensembl:ENSG00000111237 euGenes: HUgn51699
    ECgene: VPS29 H-InvDB: VPS29

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VPS29 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VPS29 gene:
    Search GeneIP for patents involving VPS29

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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