Aliases for VPS28 Gene
External Ids for VPS28 Gene
Previous GeneCards Identifiers for VPS28 Gene
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
GeneCards Summary for VPS28 Gene
VPS28 (VPS28, ESCRT-I Subunit) is a Protein Coding gene. Diseases associated with VPS28 include Noonan Syndrome 1. Among its related pathways are Vesicle-mediated transport and Budding and maturation of HIV virion. Gene Ontology (GO) annotations related to this gene include protein complex binding and ubiquitin binding.
UniProtKB/Swiss-Prot for VPS28 Gene
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.