VPS28 Gene
protein-coding GIFtS: 60
GCID: GC08M145649
|
|
vacuolar protein sorting 28 homolog (S. cerevisiae)(Previous name: vacuolar protein sorting 28 (yeast) )
| |
Aliases
for VPS28 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Vacuolar Protein Sorting 28 Homolog (S. Cerevisiae)1 2 | | H-Vps282 3 | | ESCRT-I Complex Subunit VPS282 3 | | Vacuolar Protein Sorting 28 (Yeast)1 | | Vacuolar Protein Sorting-Associated Protein 28 Homolog2 | | Yeast Class E Protein Vps28p Homolog2 |
Export aliases for VPS28 gene to outside databasesPrevious GC identifers: GC08M143252 GC08M145686 GC08M145253 GC08M145653 GC08M145620 GC08M145622 GC08M140762 |
Summaries
for VPS28 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for VPS28:
This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/lateendosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexesrequired for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I arevesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37.Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts mayexist but the proteins encoded by these transcripts have not been verified experimentally. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: VPS28_HUMAN, Q9UK41Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process
Gene Wiki entry for VPS28
|
Genomic Views
for VPS28 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_037704.5
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the VPS28 gene promoter:
ATF-2 NRSF form 1 NRSF form 2 NF-kappaB c-Ets-1 GATA-2 PPAR-gamma1 NF-kappaB2 PPAR-gamma2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for VPS28
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS28 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3VPS28 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M145649: view genomic region
(about GC identifiers)
Start:
|
145,649,000 bp from pter |
End:
|
145,653,931 bp from pter |
Size:
|
4,932 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr8-,PATCHES 145,563,760-145,568,687 |
|
Proteins
for VPS28 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VPS28_HUMAN, Q9UK41 (See
protein sequence)Recommended Name: Vacuolar protein sorting-associated protein 28 homolog Size: 221 amino acids; 25425 Da
Subunit: Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists ofTSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoechiometry. Interacts with TSG101,VPS37B, VPS37C, MVB12A and MVB12B. Interacts WITH VPS36; the interaction mediates the association with the ESCRT-IIcomplex. Interacts with SNF8 and VPS25. Interacts with CEP55
Subcellular location: Cell membrane. Late endosome membrane; Peripheral membrane protein
Secondary accessions: Q86VK0Alternative splicing: 2 isoforms: Q9UK41-1 Q9UK41-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for VPS28: NX_Q9UK41
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UK41
VPS28 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_057292.1 NP_898880.1
ENSEMBL proteins: ENSP00000434556 ENSP00000433250 ENSP00000434064 ENSP00000433228 ENSP00000433652 ENSP00000436102 ENSP00000435590 ENSP00000436509 ENSP00000431243 ENSP00000434393 ENSP00000432395 ENSP00000292510 ENSP00000366565 Reactome Protein details: Q9UK41
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
VPS28 for ontologies About GeneDecksing
VPS28 Antibody Products:
Assay Products for VPS28: |
Protein
Domains /
Families
for VPS28 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VPS28 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UK41ProtoNet protein and cluster: Q9UK41 1 Blocks protein family: IPB007143 Vacuolar protein sorting-associated
UniProtKB/Swiss-Prot: VPS28_HUMAN, Q9UK41Similarity: Belongs to the VPS28 familySimilarity: Contains 1 VPS28 C-terminal domainSimilarity: Contains 1 VPS28 N-terminal domain |
Function
for VPS28 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VPS28_HUMAN, Q9UK41Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): VPS28 (NM_016208) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VPS28 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS28 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS28 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
VPS28 for ontologies About GeneDecksing
|
Pathways & Interactions
for VPS28 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal Transduction | | | 2 | Late Phase of HIV Life Cycle | | | 3 | HIV Infection | | | 4 | Disease | | | 5 | Membrane Trafficking | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 
Reactome Pathways for VPS28 (see all 9)
1 
Kegg Pathway (Kegg details for VPS28):
VPS28 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VPS28
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/84 Interacting proteins for VPS28 (Q9UK411, 2, 3 ENSP000003665654) via UniProtKB, MINT, STRING, and/or I2D (see all 84)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TSG101 | Q998161, 2, 3, ENSP000002519684 | EBI-727424,EBI-346882 MINT-6173737 MINT-6173772 I2D:
score=9 STRING: ENSP00000251968 | | VPS37B | Q9H9H42, 3, ENSP000002672024 | MINT-6173737 MINT-6173772 I2D:
score=3 STRING: ENSP00000267202 | | UBC | P0CG482, 3, ENSP000003448184 | MINT-15048 I2D:
score=2 STRING: ENSP00000344818 | | ASF1A | Q9Y2943, ENSP000002295954 | I2D:
score=4 STRING: ENSP00000229595 | | VPS37A | Q8NEZ23, ENSP000003186294 | I2D:
score=2 STRING: ENSP00000318629 |
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
VPS28 for ontologies About GeneDecksing
|
Drugs & Compounds
for VPS28 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VPS28
Search CenterWatch for drugs/clinical trials and news about VPS28
|
Transcripts
for VPS28 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VPS28 gene (2 alternative transcripts): NM_016208.2 NM_183057.1 Unigene Cluster for VPS28: Vacuolar protein sorting 28 homolog (S. cerevisiae) Hs.418175 [show with all ESTs]Unigene Representative Sequence: BC05071217 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000529182 ENST00000526977 ENST00000526054 ENST00000526204 ENST00000530983
ENST00000528142 ENST00000530836 ENST00000530804 ENST00000527797 ENST00000533806
ENST00000531032 ENST00000531924 ENST00000526734 ENST00000530790 ENST00000524521
ENST00000292510(uc003zcs.1) ENST00000377348(uc003zct.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): VPS28 (NM_016208) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VPS28 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS28 |
Additional cDNA sequence: AF182844.1 AF316887.1 AK026865.1 AK310062.1 BC006485.1 BC019321.1 BC050712.1 BC050713.2 24/36 DOTS entries (see all 36): DT.75199002 DT.100850481 DT.97802701 DT.95159209 DT.75140456 DT.100672326 DT.97864710 DT.433805 DT.100672323 DT.121484289 DT.100672333 DT.121484246 DT.100672339 DT.40315710 DT.91757882 DT.97864713 DT.99984654 DT.100672338 DT.121484291 DT.100672321 DT.121484231 DT.121484282 DT.92011321 DT.95159158 24/446 AceView cDNA sequences (see all 446): CR591710 AI027256 BM708550 AI445816 BC050713 CR615683 AW953711 BM478527 CA308437 CR603930 BX384781 BQ018292 AV710103 AI459958 CR600507 CB160419 BQ890455 AA357363 BX282132 BQ417046 BX379007 BU658837 BQ934279 BQ581773
GeneLoc Exon Structure
5/24 Alternative Splicing Database (ASD) splice patterns (SP) for VPS28 (see all 24) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f | · | 6g | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | · | 8c | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | - | | - | | - | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 8d | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | · | 10d | · | 10e |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for VPS28
|
Expression
for VPS28 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VPS28 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGAGCCCG
About this image
See VPS28 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VPS28
SOURCE GeneReport for Unigene cluster: Hs.418175
SABiosciences Custom PCR Arrays for VPS28
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VPS28
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VPS28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VPS28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS28 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS28 |
Orthologs
for VPS28 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for VPS28 gene from 9/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Vps281 , 5 |
vacuolar protein sorting 28 (yeast)1, 5 |
87.93(n)1
98.64(a)1 |
|
15 (36.17 cM)5
669141 NM_025842.31 NP_080118.11
766220885 |
lizard
(Anolis carolinensis) |
Reptilia |
VPS286 |
-- |
91(a) |
1 ↔ 1 |
GL343892.1(109745-121741) |
African clawed frog
(Xenopus laevis) |
Amphibia |
vps28-prov2 |
vacuolar protein sorting 28 (yeast) |
79.25(n) |
|
BC056011.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc660782 |
similar to vacuolar protein sorting 28 |
82.55(n) |
|
393562 BC056741.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Vps281 , 3 |
Vacuolar protein sorting 281 |
64(a)3
68.46(n)1
64.22(a)1 |
|
44A43
474081 NM_143796.31 NP_652053.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y87G2A.103
vps-281 |
Protein VPS-281 |
46(a)3
52.09(n)1
47.24(a)1 |
|
I(13594318-13596874)3
1732291 NM_060981.41 NP_493382.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
VPS28(YPL065W)4
VPS281 |
Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, more4
Vps28p1 |
45.01(n)1
34.52(a)1 |
|
16(427927-428655)4
8560401, 4 NP_015260.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
VPS28-21 |
vacuolar protein sorting-associated protein 28-2 |
49.65(n)
42.71(a) |
|
825842 NM_116739.3 NP_567281.2 |
rice
(Oryza sativa) |
Liliopsida |
Os01g07810001 |
hypothetical protein |
54.97(n)
41.36(a) |
|
4327840 NM_001050976.1 NP_001044441.1 |
ENSEMBL Gene Tree for VPS28 (if available)
TreeFam Gene Tree for VPS28 (if available) |
Paralogs
for VPS28 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for VPS28 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VPS28 (145649000 - 145653931 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for VPS28
6 CNVs: 30308 4613 3752 53129 30309 30306 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VPS28 |
|
Disorders
/ Diseases
for VPS28 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
VPS28 for disorders About GeneDecksing
OMIM gene information: 611952
OMIM disorders: --
2  diseases for VPS28: About MalaCardsinfluenza anemia
Export disorders for VPS28 gene to outside databases
|
Publications
for VPS28 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VPS28 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with VPS28) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. (PubMed id 15218037)1, 2, 9 Stuchell M.D....Sundquist W.I. (2004)
- Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. (PubMed id 18005716)1, 2, 9 Morita E....Sundquist W.I. (2007)
- Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. (PubMed id 18539118)1, 2 Im Y.J. and Hurley J.H. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The protein network of HIV budding. (PubMed id 14505570)1, 2 von Schwedler U.K.... Sundquist W.I. (2003)
- Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. (PubMed id 11916981)1, 2 Bishop N.... Woodman P. (2002)
- Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. (PubMed id 15509564)1, 9 Eastman S.W.... Bieniasz P.D. (2005)
- Bcr interacts with components of the endosomal sorting complex required for transport-I and is required for epidermal growth factor receptor turnover. (PubMed id 16778200)1, 9 Olabisi O.O....Whitehead I.P. (2006)
- The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B. (PubMed id 16004603)1, 9 Katoh K....Maki M. (2005)
- The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. (PubMed id 22405001)1 Agromayor M....Williams R.L. (2012)
|
External Searches for VPS28 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VPS28 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing VPS28 gene
(According to HUGE)
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Specialized Databases showing VPS28 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for VPS28 gene:
Search GeneIP for patents involving VPS28
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for VPS28 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for VPS28 | | OriGene shRNA RFP for VPS28 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VPS28 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VPS28 | | | OriGene Protein Over-expression Lysate for VPS28 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VPS28 | | OriGene 3'-UTR Clone for VPS28 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VPS28 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for VPS28 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VPS28 | | OriGene Custom Protein Services for VPS28 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VPS28 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VPS28 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS28 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VPS28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VPS28 |
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| | | | Search Tocris compounds for VPS28 |
| |  |  |  |  | | | | | | Recombinant Protein for VPS28 |
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 | | | VPS28 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS28 |
|  |  |  | | | | ThermoFisher Antibodies for VPS28 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VPS28 |
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