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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VPS13C Gene

protein-coding   GIFtS: 50
GCID: GC15M062144

Vacuolar Protein Sorting 13 Homolog C (S. Cerevisiae)

(Previous name: vacuolar protein sorting 13C (yeast))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Vacuolar Protein Sorting 13 Homolog C (S. Cerevisiae)1 2
Vacuolar Protein Sorting 13C (Yeast)1
Vacuolar Protein Sorting-Associated Protein 13C2
KIAA14213

External Ids:    HGNC: 235941   Entrez Gene: 548322   Ensembl: ENSG000001290037   OMIM: 6088795   UniProtKB: Q709C83   

Export aliases for VPS13C gene to outside databases

Previous GC identifers: GC15M059860 GC15M059931 GC15M038966


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VPS13C Gene:
This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results
in multiple transcript variants. (provided by RefSeq, Oct 2010)

GeneCards Summary for VPS13C Gene: 
VPS13C (vacuolar protein sorting 13 homolog C (S. cerevisiae)) is a protein-coding gene. Diseases associated with VPS13C include chorea-acanthocytosis, and acanthocytosis. An important paralog of this gene is VPS13B.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VPS13C gene promoter:
         USF1   AML1a   FOXO3   NF-E2 p45   POU3F2   Egr-2   USF-1   Pax-4a   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVPS13C promoter sequence
   Search SABiosciences Chromatin IP Primers for VPS13C

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VPS13C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.2   Ensembl cytogenetic band:  15q22.2   HGNC cytogenetic band: 15q21.3

VPS13C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VPS13C gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M062144:  view genomic region     (about GC identifiers)

Start:
62,144,588 bp from pter      End:
62,352,672 bp from pter
Size:
208,085 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VP13C_HUMAN, Q709C8 (See protein sequence)
Recommended Name: Vacuolar protein sorting-associated protein 13C  
Size: 3753 amino acids; 422390 Da
Sequence caution: Sequence=BAA90972.1; Type=Erroneous initiation; Sequence=BAA92659.1; Type=Erroneous initiation;
Secondary accessions: Q6ISR4 Q702P2 Q702P3 Q709C9 Q9NXN8 Q9P2C6
Alternative splicing: 4 isoforms:  Q709C8-1   Q709C8-2   Q709C8-3   Q709C8-4   

Explore the universe of human proteins at neXtProt for VPS13C: NX_Q709C8

Explore proteomics data for VPS13C at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q709C8

  • VPS13C Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    VPS13C Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001018098.1  NP_060154.3  NP_060550.2  NP_065872.1  

    ENSEMBL proteins: 
     ENSP00000249837   ENSP00000261517   ENSP00000379233   ENSP00000379235  

    Human Recombinant Protein Products for VPS13C: 
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    Cloud-Clone Corp. CLIAs for VPS13C


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR026847 VPS13
     IPR015412 Autophagy-rel_C
     IPR009543 VPSAP_dom
     IPR026854 VPS13A_N

    Graphical View of Domain Structure for InterPro Entry Q709C8

    ProtoNet protein and cluster: Q709C8

    1 Blocks protein domain: IPB009543 Protein of unknown function DUF1162

    UniProtKB/Swiss-Prot: VP13C_HUMAN, Q709C8
    Similarity: Belongs to the VPS13 family


    VPS13C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for VPS13C:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for VPS13C 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for VPS13C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VPS13C 
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    SwitchGear 3'UTR luciferase reporter plasmidVPS13C 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS13C


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VPS13C

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for VPS13C (Q709C83 ENSP000002615174) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB24Q969Q53I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VPS13C (VP13C)

    Search CenterWatch for drugs/clinical trials and news about VPS13C / VP13C

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for VPS13C gene (4 alternative transcripts): 
    NM_001018088.2  NM_017684.4  NM_018080.3  NM_020821.2  

    Unigene Cluster for VPS13C:

    Vacuolar protein sorting 13 homolog C (S. cerevisiae)
    Hs.511668  [show with all ESTs]
    Unigene Representative Sequence: NM_001018088
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000249837(uc002aha.3) ENST00000261517(uc002agz.3) ENST00000560637
    ENST00000559119 ENST00000395896(uc002ahb.2 uc002ahc.2) ENST00000395898
    ENST00000558919 ENST00000558338(uc002ahd.1) ENST00000558088 ENST00000561258

    miRNA
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    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate VPS13C (see all 51):
    hsa-miR-2052 hsa-miR-4307 hsa-miR-607 hsa-miR-106a hsa-miR-938 hsa-miR-29a hsa-miR-30d hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidVPS13C 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for VPS13C
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VPS13C
    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VPS13C
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VPS13C

    Additional mRNA sequence: 

    AB037842.1 AJ608770.1 AJ608771.1 AJ626860.1 AJ626861.1 AK000143.1 AK001243.1 AK025014.1 
    AK025364.1 AK056744.1 AK123851.1 AK128650.1 AK304408.1 AK307518.1 AL833377.1 BC069387.1 
    BX648470.1 BX648766.1 CR936716.1 

    15 DOTS entries:

    DT.311680  DT.102828000  DT.87046481  DT.91814093  DT.91764214  DT.401945  DT.309340  DT.40239598 
    DT.452212  DT.100777440  DT.91721406  DT.121073045  DT.100777439  DT.75183345  DT.95147891 

    24/225 AceView cDNA sequences (see all 225):

    AJ608770 AA284312 AB037842 AA305956 BE045929 BE222324 BM670088 AI393840 
    BU679870 AW591906 AW858807 AL833377 AW014566 BF224116 BP379432 BP344355 
    BF514622 AL040500 AA292722 C21371 BM930556 NM_017684 AJ608771 AJ626860 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for VPS13C (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^
    SP1:                                                                                                                                                            
    SP2:                                -     -                                                                                                                     
    SP3:                                                                                                                                                            
    SP4:                                -     -                                                                                                                     
    SP5:                                                                                                                                                            

    ExUns: 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41 ^ 42 ^ 43 ^ 44 ^ 45 ^ 46 ^ 47 ^ 48 ^ 49 ^ 50 ^ 51 ^ 52 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 53 ^ 54 ^ 55 ^ 56 ^ 57 ^ 58 ^ 59 ^ 60a · 60b ^ 61 ^ 62 ^ 63 ^ 64 ^ 65 ^ 66a · 66b ^ 67 ^ 68 ^ 69 ^ 70 ^ 71 ^ 72 ^ 73 ^ 74 ^ 75 ^ 76 ^
    SP1:                                                                                            -                                                               
    SP2:                                                                                            -                                                               
    SP3:                                                                                            -                                                               
    SP4:                                                                                            -                                                               
    SP5:                                                                                                                                                            

    ExUns: 77 ^ 78 ^ 79 ^ 80 ^ 81 ^ 82 ^ 83a · 83b ^ 84 ^ 85 ^
    SP1:                                -     -                     
    SP2:                                -     -                     
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for VPS13C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VPS13C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTTTAAGG
    VPS13C Expression
    About this image


    See VPS13C Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VPS13C

    SOURCE GeneReport for Unigene cluster: Hs.511668

    UniProtKB/Swiss-Prot: VP13C_HUMAN, Q709C8
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for VPS13C
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VPS13C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for VPS13C gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vps13c1 , 5 vacuolar protein sorting 13C (yeast)1, 5 84.42(n)1
    86.61(a)1
      9 (36.77 cM)5
    3205281  NM_177184.31  NP_796158.21 
     678403965 
    chicken
    (Gallus gallus)
    Aves VPS13C1 vacuolar protein sorting 13 homolog C (S. cerevisiae) 71.52(n)
    69.27(a)
      415376  XM_001232999.2  XP_001233000.2 
    lizard
    (Anolis carolinensis)
    Reptilia VPS13C6
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343428.1(774975-838032)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7987461 similar to vacuolar protein sorting 13C (yeast) 62.17(n)
    61.13(a)
      798746  XM_001922732.2  XP_001922767.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Vps136
    Vacuolar protein sorting 13
    30(a)
    1 → many
    2R(3454336-3468180)
    worm
    (Caenorhabditis elegans)
    Secernentea T08G11.16
    Protein T08G11.1, isoform b
    28(a)
    1 → many
    I(8905639-8916807)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS136
    Protein of unknown function; heterooligomeric or h...
    20(a)
    1 → many
    XII(54211-63645)


    ENSEMBL Gene Tree for VPS13C (if available)
    TreeFam Gene Tree for VPS13C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for VPS13C gene
    VPS13B2  VPS13D2  VPS13A2  
    1 SIMAP similar gene for VPS13C using alignment to 1 protein entry:     VP13C_HUMAN:
    VPS13A

    VPS13C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4866 SNPs in VPS13C are shown (see all 4866)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs785873221,2
    C--38982981(+) AAAAA-/TWCATC 4 -- int10--------
    rs340319181,2
    C--39016859(+) TCTTC-/AAAAAA 4 -- int11Minor allele frequency- A:0.00NA 2
    rs356378541,2
    C--39018820(+) AAAAAA/-TGTGA 4 -- int11Minor allele frequency- -:0.00NA 2
    rs113778341,2
    C--39037742(+) AAAAA-/AGGAAG 4 -- int1 trp31Minor allele frequency- A:0.50NA 2
    rs624022381,2
    C--39120148(-) CAAGCA/CAATGG 4 -- int10--------
    rs58131281,2
    C,F--39151020(+) TAATTA/-AAGTC 4 -- int14Minor allele frequency- -:0.38NA CSA 8
    rs1500724331,2
    --42205985(+) CCAGAA/CTGCCA 2 -- ds50010--------
    rs1844923721,2
    --42205994(+) CATGCA/CGTCTA 2 -- ds50010--------
    rs1454067981,2
    --42206033(+) TCTTCA/CAGCCA 2 -- ds50010--------
    rs1413655601,2
    --42206041(+) CCAAAC/GTCGGC 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for VPS13C (62144588 - 62352672 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for VPS13C (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2749762CNV Deletion23290073
    esv2582405CNV Deletion19546169
    esv273087CNV Insertion20981092
    esv1275705CNV Insertion17803354
    esv270546CNV Insertion20981092
    nsv521334CNV Loss19592680
    dgv2395n71CNV Loss21882294
    dgv2394n71CNV Loss21882294
    nsv457178CNV Loss19166990
    nsv457177CNV Loss19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608879    OMIM disorders: --

    4 diseases for VPS13C:    About MalaCards
    chorea-acanthocytosis    acanthocytosis    congenital myasthenic syndrome    chorea

    1 disease from the University of Copenhagen DISEASES database for VPS13C:
    chorea-acanthocytosis

    VPS13C for disorders           About GeneDecksing

    Genetic Association Database (GAD): VPS13C
    Human Genome Epidemiology (HuGE) Navigator: VPS13C (4 documents)

    Export disorders for VPS13C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VPS13C gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with VPS13C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. (PubMed id 20081857)1, 4 Saxena R....Zhao J.H. (2010)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
    3. Analysis of the human VPS13 gene family. (PubMed id 15498460)1, 2 Velayos-Baeza A....Monaco A.P. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
    7. Loci associated with N-glycosylation of human immunogl obulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (2013)
    8. Genetic variants in GCKR, GIPR, ADCY5 and VPS13C and t he risk of severe sulfonylurea-induced hypoglycaemia in patients with type 2 dia betes. (PubMed id 22956255)1 Holstein J.D....Holstein A. (2013)
    9. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resi stance. (PubMed id 22581228)1 Manning A.K....Langenberg C. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54832 HGNC: 23594 AceView: VPS13C Ensembl:ENSG00000129003 euGenes: HUgn54832
    ECgene: VPS13C H-InvDB: VPS13C

    (According to HUGE)
    About This Section
    HUGE: KIAA1421

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VPS13C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VPS13C gene:
    Search GeneIP for patents involving VPS13C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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