Aliases for VPS11 Gene
External Ids for VPS11 Gene
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
GeneCards Summary for VPS11 Gene
VPS11 (Vacuolar Protein Sorting 11 Homolog (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with VPS11 include chronic apical periodontitis. GO annotations related to this gene include nucleotide binding.
UniProtKB/Swiss-Prot for VPS11 Gene
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.