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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VOPP1 Gene

protein-coding   GIFtS: 49
GCID: GC07M055503

Vesicular, Overexpressed In Cancer, Prosurvival Protein...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Vesicular, Overexpressed In Cancer, Prosurvival Protein 11 2     GASP2 3 5
EGFR-Coamplified And Overexpressed Protein1 2 3     Putative NF-Kappa-B-Activating Protein 055N2 3
Glioblastoma-Amplified Secreted Protein1 2 3     Hypothetical Protein DKFZp564K08222
ECOP2 3 5     ECop3

External Ids:    HGNC: 345181   Entrez Gene: 815522   Ensembl: ENSG000001549787   OMIM: 6119155   UniProtKB: Q96AW13   

Export aliases for VOPP1 gene to outside databases

Previous GC identifer: GC07M055374


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for VOPP1 Gene: 
VOPP1 (vesicular, overexpressed in cancer, prosurvival protein 1) is a protein-coding gene. Diseases associated with VOPP1 include glioblastoma, and cervical adenocarcinoma. GO annotations related to this gene include signal transducer activity.

UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding
and associated apoptotic response, when overexpressed

Gene Wiki entry for VOPP1 (ECOP) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_033968.6  NC_018918.2  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for VOPP1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 7): VOPP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for VOPP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VOPP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p11.2   Ensembl cytogenetic band:  7p11.2   HGNC cytogenetic band: 7p11.2

VOPP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VOPP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M055503:  view genomic region     (about GC identifiers)

Start:
55,503,749 bp from pter      End:
55,640,681 bp from pter
Size:
136,933 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 55,542,585-55,644,447     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1 (See protein sequence)
Recommended Name: Vesicular, overexpressed in cancer, prosurvival protein 1 precursor  
Size: 172 amino acids; 19224 Da
Subcellular location: Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed,
localizes in the nucleus and perinuclear regions
Sequence caution: Sequence=AAK82888.1; Type=Erroneous translation; Note=Wrong choice of frame;
Secondary accessions: B0AZU1 B2RAT4 B3KS72 Q6FIE3 Q8NBN8 Q96RE5 Q9H0W4
Alternative splicing: 3 isoforms:  Q96AW1-1   Q96AW1-2   Q96AW1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VOPP1: NX_Q96AW1

Explore proteomics data for VOPP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96AW1

  • VOPP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    VOPP1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001271211.1  NP_001271212.1  NP_001271213.1  NP_110423.3  

    ENSEMBL proteins: 
     ENSP00000285279   ENSP00000415230   ENSP00000413948   ENSP00000389601   ENSP00000393210  
     ENSP00000411447   ENSP00000395533   ENSP00000407356   ENSP00000407579   ENSP00000416530  
     ENSP00000411737   ENSP00000408161   ENSP00000395131   ENSP00000446442  

    Human Recombinant Protein Products for VOPP1: 
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    Novus Biologicals VOPP1 Proteins
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for VOPP1
    Cloud-Clone Corp. Proteins for VOPP1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IDA--
    GO:0030659cytoplasmic vesicle membrane IDA--
    GO:0031301integral to organelle membrane IDA--

    VOPP1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026229 VOPP1

    Graphical View of Domain Structure for InterPro Entry Q96AW1

    ProtoNet protein and cluster: Q96AW1

    UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
    Similarity: Belongs to the VOPP1/ECOP family


    VOPP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VOPP1_HUMAN, Q96AW1
    Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding
    and associated apoptotic response, when overexpressed

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
         
    VOPP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for VOPP1:
     Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for VOPP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for VOPP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VOPP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VOPP1 

    miRNA
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    miRTarBase miRNAs that target VOPP1:
    hsa-mir-218 (MIRT004541)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VOPP1
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate VOPP1 (see all 25):
    hsa-miR-3678-3p hsa-miR-30c hsa-miR-4311 hsa-miR-4254 hsa-miR-631 hsa-miR-486-3p hsa-miR-30d hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidVOPP1 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of VOPP1 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VOPP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VOPP1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/17 Interacting proteins for VOPP1 (Q96AW13 ENSP000002852794) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MTF2Q9Y4833, ENSP000003593214I2D: score=1 STRING: ENSP00000359321
    C8orf33Q9H7E93I2D: score=1 
    CRIP1P502383I2D: score=1 
    GLYATQ6IB773I2D: score=1 
    HMOX2P305193I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007165signal transduction IMP12761501

    VOPP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VOPP1

    Search CenterWatch for drugs/clinical trials and news about VOPP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for VOPP1 gene (4 alternative transcripts): 
    NM_001284282.1  NM_001284283.1  NM_001284284.1  NM_030796.3  

    Unigene Cluster for VOPP1:

    Vesicular, overexpressed in cancer, prosurvival protein 1
    Hs.488307  [show with all ESTs]
    Unigene Representative Sequence: AK126848
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000462326 ENST00000285279(uc010kzi.3 uc003tqs.3) ENST00000433959(uc003tqq.3)
    ENST00000428648(uc011kcr.2) ENST00000428097 ENST00000418904 ENST00000454227
    ENST00000453256 ENST00000427700 ENST00000455023 ENST00000414113 ENST00000417399
    ENST00000481197 ENST00000452832 ENST00000453112 ENST00000471168 ENST00000545390(uc010kzh.3)

    miRNA
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    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate VOPP1 (see all 25):
    hsa-miR-3678-3p hsa-miR-30c hsa-miR-4311 hsa-miR-4254 hsa-miR-631 hsa-miR-486-3p hsa-miR-30d hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidVOPP1 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VOPP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VOPP1

    Additional mRNA sequence: 

    AB097004.1 AF395824.1 AK000539.1 AK075391.1 AK090825.1 AK092992.1 AK126848.1 AK225755.1 
    AK309288.1 AK314338.1 AK315882.1 AL136610.1 BC016650.1 CR533483.1 

    24 DOTS entries:

    DT.97772732  DT.455806  DT.100731418  DT.91859296  DT.100031062  DT.100815455  DT.100815453  DT.121100173 
    DT.99964077  DT.100815458  DT.121100241  DT.100815457  DT.102844864  DT.121100140  DT.121100152  DT.121100224 
    DT.121100226  DT.121100237  DT.121460203  DT.121460411  DT.95123860  DT.101967680  DT.121100138  DT.121460604 

    24/378 AceView cDNA sequences (see all 378):

    BM997768 BF432684 CF541266 BX956224 AA862278 BU630500 BQ638556 BG110964 
    CD107342 AX746636 CD366489 BQ446273 BU627451 BM998113 BE878057 CR606724 
    BG678931 BM990448 BM666268 AK090825 CA748494 BU075594 AW243364 BU507685 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for VOPP1 (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c ^ 16 ^ 17a ·
    SP1:                                                  -     -     -     -     -     -           -                 -     -     -                                 
    SP2:                                                                    -     -     -           -                 -     -     -                                 
    SP3:        -     -     -     -     -     -     -     -     -     -     -     -     -           -                                                               
    SP4:                          -     -     -     -     -     -     -     -     -     -           -                 -     -     -                                 
    SP5:                          -     -     -                 -     -     -     -     -           -                 -     -     -                                 

    ExUns: 17b · 17c · 17d · 17e · 17f · 17g · 17h · 17i
    SP1:                                                
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for VOPP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VOPP1 expression in normal human tissues (normalized intensities)      VOPP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTCCTCT
    VOPP1 Expression
    About this image


    VOPP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Blood (Cardiovascular System)
             Double Positive Thymocytes Thymus
     
     Oral Cavity (Gastrointestinal Tract)
             saliva   
     
     Larynx (Respiratory System)

    See VOPP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VOPP1

    SOURCE GeneReport for Unigene cluster: Hs.488307

    UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
    Tissue specificity: Widely expressed with highest levels in thymus and ovary

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VOPP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for VOPP1 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vopp11 , 5 vesicular, overexpressed in cancer, prosurvival protein more1, 5 84.11(n)1
    89.53(a)1
      6 (27.82 cM)5
    2320231  NM_146168.11  NP_666280.11 
     577278075 
    chicken
    (Gallus gallus)
    Aves VOPP11 vesicular, overexpressed in cancer, prosurvival protein more 74.95(n)
    86.96(a)
      776358  XM_001235487.2  XP_001235488.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.197412 Xenopus laevis transcribed sequence with moderate similarity more 77.15(n)    CD253216.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-24c2.91 si:dkey-24c2.9 54.08(n)
    48.34(a)
      100007510  NM_001115072.1  NP_001108544.1 


    ENSEMBL Gene Tree for VOPP1 (if available)
    TreeFam Gene Tree for VOPP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2218 SNPs in VOPP1 are shown (see all 2218)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1439802721,2
    --55537853(+) GGCCAA/GTGGTT 1 -- int10--------
    rs1486351801,2
    --55537877(+) GGAAAC/TGCAGT 1 -- int10--------
    rs26918501,2
    F--55537884(-) gggtcT/Acactg 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1113288831,2
    F--55537891(+) ACCCCG/ATCTCT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs17229851,2
    C,F,H--55537903(-) ATTTTA/GTGTTT 1 -- int115Minor allele frequency- G:0.13EA NA WA CSA 513
    rs171724861,2
    C,F,H--55538093(+) TCAGCG/AATGCT 1 -- int115Minor allele frequency- A:0.05NA NS EA WA 1626
    rs1511832211,2
    --55538125(+) GACAAC/TTGTCT 1 -- int10--------
    rs1849162981,2
    C--55538204(+) CCACCC/TACCTC 1 -- int10--------
    rs1120935581,2
    C--55538213(+) TCACCCCACT   
       GAA
    /-
    CCAAG
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs1901198081,2
    --55538221(+) CTGAAC/GCAAGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for VOPP1 (55503749 - 55640681 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for VOPP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734425CNV Deletion23290073
    esv997261CNV Deletion20482838
    esv28230CNV Gain+Loss19812545
    nsv469822CNV Complex16826518

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611915    OMIM disorders: --

    5 diseases for VOPP1:    About MalaCards
    glioblastoma    cervical adenocarcinoma    cervicitis    adenocarcinoma
    squamous cell carcinoma


    VOPP1 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: VOPP1 (0 documents)

    Export disorders for VOPP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VOPP1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with VOPP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner. (PubMed id 15735698)1, 2, 3, 9 Park S. and James C.D. (2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    6. MiR-218 sensitizes glioma cells to apoptosis and inhib its tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity. (PubMed id 23243056)1 Xia H....Jiang X. (2013)
    7. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    8. Loss of VOPP1 overexpression in squamous carcinoma ce lls induces apoptosis through oxidative cellular injury. (PubMed id 21519330)1 Baras A.S....Moskaluk C.A. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81552 HGNC: 34518 AceView: DKFZP564K0822 Ensembl:ENSG00000154978 euGenes: HUgn81552
    ECgene: VOPP1 H-InvDB: VOPP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VOPP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VOPP1 gene:
    Search GeneIP for patents involving VOPP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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