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VOPP1 Gene

protein-coding   GIFtS: 50
GCID: GC07M055503

Vesicular, Overexpressed In Cancer, Prosurvival Protein...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Vesicular, Overexpressed In Cancer, Prosurvival Protein 11 2     GASP2 3 5
EGFR-Coamplified And Overexpressed Protein1 2 3     Putative NF-Kappa-B-Activating Protein 055N2 3
Glioblastoma-Amplified Secreted Protein1 2 3     Hypothetical Protein DKFZp564K08222
ECOP2 3 5     ECop3

External Ids:    HGNC: 345181   Entrez Gene: 815522   Ensembl: ENSG000001549787   OMIM: 6119155   UniProtKB: Q96AW13   

Export aliases for VOPP1 gene to outside databases

Previous GC identifer: GC07M055374


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for VOPP1 Gene:
VOPP1 (vesicular, overexpressed in cancer, prosurvival protein 1) is a protein-coding gene. GO annotations related to this gene include signal transducer activity.

UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding
and associated apoptotic response, when overexpressed

Gene Wiki entry for VOPP1 (ECOP) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007819.18  
Regulatory elements:
   Search for regulatory transcription factor binding sites for VOPP1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 7): VOPP1 promoter sequence
   Search Chromatin IP Primers for VOPP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VOPP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p11.2   Ensembl cytogenetic band:  7p11.2   HGNC cytogenetic band: 7p11.2

VOPP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VOPP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M055503:  view genomic region     (about GC identifiers)

Start:
55,503,749 bp from pter      End:
55,640,681 bp from pter
Size:
136,933 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 55,542,585-55,644,447     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1 (See protein sequence)
Recommended Name: Vesicular, overexpressed in cancer, prosurvival protein 1 precursor  
Size: 172 amino acids; 19224 Da
Sequence caution: Sequence=AAK82888.1; Type=Erroneous translation; Note=Wrong choice of frame;
Secondary accessions: B0AZU1 B2RAT4 B3KS72 Q6FIE3 Q8NBN8 Q96RE5 Q9H0W4
Alternative splicing: 3 isoforms:  Q96AW1-1   Q96AW1-2   Q96AW1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VOPP1: NX_Q96AW1

Explore proteomics data for VOPP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See VOPP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001271211.1  NP_001271212.1  NP_001271213.1  NP_110423.3  

    ENSEMBL proteins: 
     ENSP00000285279   ENSP00000415230   ENSP00000413948   ENSP00000389601   ENSP00000393210  
     ENSP00000411447   ENSP00000395533   ENSP00000407356   ENSP00000407579   ENSP00000416530  
     ENSP00000411737   ENSP00000408161   ENSP00000395131   ENSP00000446442  

    VOPP1 Human Recombinant Protein Products:

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    Novus Biologicals VOPP1 Proteins
    Novus Biologicals VOPP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for VOPP1
    Cloud-Clone Corp. Proteins for VOPP1

     
    Search eBioscience for Proteins for VOPP1 

     
    antibodies-online proteins for VOPP1 (8 products) 

     
    antibodies-online peptides for VOPP1

    VOPP1 Antibody Products:

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    antibodies-online antibodies for VOPP1 (19 products) 

    VOPP1 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026229 VOPP1

    Graphical View of Domain Structure for InterPro Entry Q96AW1

    ProtoNet protein and cluster: Q96AW1

    UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
    Similarity: Belongs to the VOPP1/ECOP family


    Find genes that share domains with VOPP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VOPP1_HUMAN, Q96AW1
    Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding
    and associated apoptotic response, when overexpressed

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
         
    Find genes that share ontologies with VOPP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for VOPP1:
     Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for VOPP1

    miRNA
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    miRTarBase miRNAs that target VOPP1:
    hsa-mir-877-3p (MIRT036923), hsa-mir-320a (MIRT044677), hsa-mir-218-5p (MIRT004541), hsa-mir-15b-5p (MIRT046506), hsa-mir-320b (MIRT036210), hsa-mir-324-3p (MIRT042822)

    Block miRNA regulation of human, mouse, rat VOPP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VOPP1 (see all 25):
    hsa-miR-3678-3p hsa-miR-30c hsa-miR-4311 hsa-miR-4254 hsa-miR-631 hsa-miR-486-3p hsa-miR-30d hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidVOPP1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: VOPP1 (NM_030796)
    Sino Biological Human cDNA Clone for VOPP1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VOPP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VOPP1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VOPP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VOPP1_HUMAN, Q96AW1: Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed,
    localizes in the nucleus and perinuclear regions
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome4
    extracellular3
    plasma membrane3
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IDA--
    GO:0030659cytoplasmic vesicle membrane IDA--
    GO:0031301integral component of organelle membrane IDA--

    Find genes that share ontologies with VOPP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VOPP1
    Interactions:

        Search GeneGlobe Interaction Network for VOPP1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for VOPP1 (Q96AW13 ENSP000002852794) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MTF2Q9Y4833, ENSP000003593214I2D: score=1 STRING: ENSP00000359321
    C8orf33Q9H7E93I2D: score=1 
    CRIP1P502383I2D: score=1 
    GLYATQ6IB773I2D: score=1 
    HMOX2P305193I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007165signal transduction IMP12761501

    Find genes that share ontologies with VOPP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VOPP1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for VOPP1 gene (4 alternative transcripts): 
    NM_001284282.1  NM_001284283.1  NM_001284284.1  NM_030796.3  

    Unigene Cluster for VOPP1:

    Vesicular, overexpressed in cancer, prosurvival protein 1
    Hs.488307  [show with all ESTs]
    Unigene Representative Sequence: AK126848
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000462326 ENST00000285279(uc010kzi.3 uc003tqs.3) ENST00000433959(uc003tqq.3)
    ENST00000428648(uc011kcr.2) ENST00000428097 ENST00000418904 ENST00000454227
    ENST00000453256 ENST00000427700 ENST00000455023 ENST00000414113 ENST00000417399
    ENST00000481197 ENST00000452832 ENST00000453112 ENST00000471168 ENST00000545390(uc010kzh.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat VOPP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VOPP1 (see all 25):
    hsa-miR-3678-3p hsa-miR-30c hsa-miR-4311 hsa-miR-4254 hsa-miR-631 hsa-miR-486-3p hsa-miR-30d hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidVOPP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat VOPP1
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    GenScript: all cDNA clones in your preferred vector: VOPP1 (NM_030796)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VOPP1
    Primer
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    OriGene qPCR primer pairs and template standards for VOPP1
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    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat VOPP1
      QuantiTect SYBR Green Assays in human, mouse, rat VOPP1
      QuantiFast Probe-based Assays in human, mouse, rat VOPP1

    Additional mRNA sequence: 

    AB097004.1 AF395824.1 AK000539.1 AK075391.1 AK090825.1 AK092992.1 AK126848.1 AK225755.1 
    AK309288.1 AK314338.1 AK315882.1 AL136610.1 BC016650.1 CR533483.1 

    24 DOTS entries:

    DT.97772732  DT.455806  DT.100731418  DT.91859296  DT.100031062  DT.100815455  DT.100815453  DT.121100173 
    DT.99964077  DT.100815458  DT.121100241  DT.100815457  DT.102844864  DT.121100140  DT.121100152  DT.121100224 
    DT.121100226  DT.121100237  DT.121460203  DT.121460411  DT.95123860  DT.101967680  DT.121100138  DT.121460604 

    Selected AceView cDNA sequences (see all 378):

    BU507685 BE878057 CA748494 BM708399 BM997768 BQ637501 CD366489 BM693055 
    AA862278 BU178749 AW243364 CO248264 BQ446273 BX284094 BQ421973 CA437966 
    AA082143 BM990448 BM998113 BX956224 BM555009 AW328067 BG696226 BQ638915 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for VOPP1 (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c ^ 16 ^ 17a ·
    SP1:                                                  -     -     -     -     -     -           -                 -     -     -                                 
    SP2:                                                                    -     -     -           -                 -     -     -                                 
    SP3:        -     -     -     -     -     -     -     -     -     -     -     -     -           -                                                               
    SP4:                          -     -     -     -     -     -     -     -     -     -           -                 -     -     -                                 
    SP5:                          -     -     -                 -     -     -     -     -           -                 -     -     -                                 

    ExUns: 17b · 17c · 17d · 17e · 17f · 17g · 17h · 17i
    SP1:                                                
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for VOPP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VOPP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTCCTCT
    VOPP1 Expression
    About this image


    VOPP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Blood (Cardiovascular System)
             Double Positive Thymocytes Thymus
     
     Larynx (Respiratory System)
    VOPP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VOPP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.488307

    UniProtKB/Swiss-Prot: VOPP1_HUMAN, Q96AW1
    Tissue specificity: Widely expressed with highest levels in thymus and ovary

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VOPP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for VOPP1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vopp11 , 5 vesicular, overexpressed in cancer, prosurvival protein more1, 5 84.11(n)1
    89.53(a)1
      6 (27.82 cM)5
    2320231  NM_146168.11  NP_666280.11 
     577278075 
    chicken
    (Gallus gallus)
    Aves VOPP11 vesicular, overexpressed in cancer, prosurvival protein more 74.55(n)
    86.67(a)
      776358  XM_004939605.1  XP_004939662.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.197412 Xenopus laevis transcribed sequence with moderate similarity more 77.15(n)    CD253216.1 
    zebrafish
    (Danio rerio)
    Actinopterygii vopp11 vesicular, overexpressed in cancer, prosurvival protein more 65.38(n)
    63.87(a)
      101885019  XM_005170613.1  XP_005170670.1 


    ENSEMBL Gene Tree for VOPP1 (if available)
    TreeFam Gene Tree for VOPP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VOPP1 (see all 2218)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1439802721,2
    --55537853(+) GGCCAA/GTGGTT 1 -- int10--------
    rs1486351801,2
    --55537877(+) GGAAAC/TGCAGT 1 -- int10--------
    rs26918501,2
    F--55537884(-) gggtcT/Acactg 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1113288831,2
    F--55537891(+) ACCCCG/ATCTCT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs17229851,2
    C,F,H--55537903(-) ATTTTA/GTGTTT 1 -- int115Minor allele frequency- G:0.13EA NA WA CSA 513
    rs171724861,2
    C,F,H--55538093(+) TCAGCG/AATGCT 1 -- int115Minor allele frequency- A:0.05NA NS EA WA 1626
    rs1511832211,2
    --55538125(+) GACAAC/TTGTCT 1 -- int10--------
    rs1849162981,2
    C--55538204(+) CCACCC/TACCTC 1 -- int10--------
    rs1120935581,2
    C--55538213(+) TCACCCCACT   
       GAA
    /-
    CCAAG
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs1901198081,2
    --55538221(+) CTGAAC/GCAAGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for VOPP1 (55503749 - 55640681 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for VOPP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734425CNV Deletion23290073
    esv997261CNV Deletion20482838
    esv28230CNV Gain+Loss19812545
    nsv469822CNV Complex16826518

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611915    OMIM disorders: --


    Find genes that share disorders with VOPP1           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: VOPP1 (0 documents)

    Export disorders for VOPP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VOPP1 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with VOPP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner. (PubMed id 15735698)1, 2, 3, 9 Park S. and James C.D. (Oncogene 2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    4. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (Oncogene 2003)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    6. MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-I_B activity. (PubMed id 23243056)1 Xia H....Jiang X. (Neuro-oncology 2013)
    7. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)
    8. Loss of VOPP1 overexpression in squamous carcinoma cells induces apoptosis through oxidative cellular injury. (PubMed id 21519330)1 Baras A.S....Moskaluk C.A. ( a journal of technical methods and pathology 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81552 HGNC: 34518 AceView: DKFZP564K0822 Ensembl:ENSG00000154978 euGenes: HUgn81552
    ECgene: VOPP1 H-InvDB: VOPP1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for VOPP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for VOPP1 gene:
    Search GeneIP for patents involving VOPP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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