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Aliases for VN1R5 Gene

Aliases for VN1R5 Gene

  • Vomeronasal 1 Receptor 5 (Gene/Pseudogene) 2 3
  • G-Protein Coupled Receptor GPCR26 3 4
  • V1r-Like Receptor 5 3 4
  • HGPCR26 3 4
  • V1RL5 3 4
  • Vomeronasal Type-1 Receptor 5 3
  • Vomeronasal 1 Receptor 5 2
  • Pheromone Receptor 3
  • V1R-Like 5 3

External Ids for VN1R5 Gene

Previous GeneCards Identifiers for VN1R5 Gene

  • GC01U900013
  • GC01P243516
  • GC01P244366
  • GC01P243746
  • GC01P245485
  • GC01P247419
  • GC01P217813

Summaries for VN1R5 Gene

GeneCards Summary for VN1R5 Gene

VN1R5 (Vomeronasal 1 Receptor 5 (Gene/Pseudogene)) is a Protein Coding gene. GO annotations related to this gene include pheromone receptor activity.

UniProtKB/Swiss-Prot for VN1R5 Gene

  • Putative pheromone receptor

Gene Wiki entry for VN1R5 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VN1R5 Gene

Genomics for VN1R5 Gene

Regulatory Elements for VN1R5 Gene

Transcription factor binding sites by QIAGEN in the VN1R5 gene promoter:

Genomic Location for VN1R5 Gene

Start:
247,256,072 bp from pter
End:
247,257,145 bp from pter
Size:
1,074 bases
Orientation:
Plus strand

Genomic View for VN1R5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VN1R5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VN1R5 Gene

Proteins for VN1R5 Gene

  • Protein details for VN1R5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z5H4-VN1R5_HUMAN
    Recommended name:
    Vomeronasal type-1 receptor 5
    Protein Accession:
    Q7Z5H4
    Secondary Accessions:
    • A0AVG1
    • Q8NEU5
    • Q8TDU3

    Protein attributes for VN1R5 Gene

    Size:
    357 amino acids
    Molecular mass:
    40779 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The chimpanzee and orangutan orthologous proteins do not exist, their genes are pseudogenes

neXtProt entry for VN1R5 Gene

Proteomics data for VN1R5 Gene at MOPED

Post-translational modifications for VN1R5 Gene

  • Glycosylation at Asn297
  • Modification sites at PhosphoSitePlus

Other Protein References for VN1R5 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for VN1R5 Gene

Domains for VN1R5 Gene

Gene Families for VN1R5 Gene

HGNC:
  • VN1RU :GPCR / Unclassified : Vomeronasal receptors, type 1
  • VN1R :Vomeronasal receptors / Type 1

Protein Domains for VN1R5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for VN1R5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z5H4

UniProtKB/Swiss-Prot:

VN1R5_HUMAN :
  • Q7Z5H4
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with VN1R5: view

Function for VN1R5 Gene

Molecular function for VN1R5 Gene

UniProtKB/Swiss-Prot Function: Putative pheromone receptor

Gene Ontology (GO) - Molecular Function for VN1R5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016503 pheromone receptor activity IEA --
genes like me logo Genes that share ontologies with VN1R5: view

Phenotypes for VN1R5 Gene

genes like me logo Genes that share phenotypes with VN1R5: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for VN1R5 Gene

Localization for VN1R5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VN1R5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for VN1R5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with VN1R5: view

No data available for Subcellular locations from COMPARTMENTS for VN1R5 Gene

Pathways for VN1R5 Gene

SuperPathways for VN1R5 Gene

No Data Available

Interacting Proteins for VN1R5 Gene

Gene Ontology (GO) - Biological Process for VN1R5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0019236 response to pheromone IEA --
genes like me logo Genes that share ontologies with VN1R5: view

No data available for Pathways by source for VN1R5 Gene

Transcripts for VN1R5 Gene

mRNA/cDNA for VN1R5 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for VN1R5 Gene

No ASD Table

Relevant External Links for VN1R5 Gene

GeneLoc Exon Structure for
VN1R5
ECgene alternative splicing isoforms for
VN1R5

Expression for VN1R5 Gene

mRNA expression in normal human tissues for VN1R5 Gene

mRNA differential expression in normal tissues according to GTEx for VN1R5 Gene

This gene is overexpressed in Testis (6.7).

SOURCE GeneReport for Unigene cluster for VN1R5 Gene Hs.553686

genes like me logo Genes that share expressions with VN1R5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for VN1R5 Gene

Orthologs for VN1R5 Gene

Evolution for VN1R5 Gene

ENSEMBL:
Gene Tree for VN1R5 (if available)
TreeFam:
Gene Tree for VN1R5 (if available)

No data available for Orthologs for VN1R5 Gene

Paralogs for VN1R5 Gene

Selected SIMAP similar genes for VN1R5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with VN1R5: view

No data available for Paralogs for VN1R5 Gene

Variants for VN1R5 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for VN1R5 Gene

Q7Z5H4-VN1R5_HUMAN
There is an allele VN1R5*2 with a truncating mutation in position 46. It was found with a frequency of about 32%

Sequence variations from dbSNP and Humsavar for VN1R5 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1771925 -- 247,257,557(-) AATAC(C/T)CGTTA downstream-variant-500B
rs1771926 -- 247,255,041(-) CTAAA(A/C)ATACA upstream-variant-2KB
rs1771927 -- 247,255,020(-) CGGGC(A/G)TGGTG upstream-variant-2KB
rs1778539 -- 247,255,164(-) GGTGC(A/G)GTTAT upstream-variant-2KB
rs2386528 -- 247,254,214(+) GCCTG(A/G)CTTAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for VN1R5 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv833126 CNV Loss 17160897
nsv5299 CNV Insertion 18451855

Relevant External Links for VN1R5 Gene

HapMap Linkage Disequilibrium report
VN1R5

Disorders for VN1R5 Gene

No disorders were found for VN1R5 Gene.

No data available for UniProtKB/Swiss-Prot for VN1R5 Gene

Publications for VN1R5 Gene

  1. Novel human vomeronasal receptor-like genes reveal species-specific families. (PMID: 12123587) Rodriguez I. … Mombaerts P. (Curr. Biol. 2002) 2 3 4
  2. Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates. (PMID: 12826614) Zhang J. … Webb D.M. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 3 4
  5. Extreme variability among mammalian V1R gene families. (PMID: 19952141) Young J.M. … Trask B.J. (Genome Res. 2010) 3

Products for VN1R5 Gene

Sources for VN1R5 Gene

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