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vomeronasal 1 receptor 3 (gene/pseudogene)(Previous names: vomeronasal 1 receptor 3, vomeronasal 1 receptor 3 pseudogene...)
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Aliases
for VN1R3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Vomeronasal 1 Receptor 3 (Gene/Pseudogene)1 2 | | Vomeronasal 1 Receptor 3 Pseudogene1 | | V1RL31 2 3 | | V1RL3p2 | | FKSG461 | | V1r-Like Receptor 33 | | Vomeronasal 1 Receptor 31 | | |
| External Ids: | HGNC: 198671 | Entrez Gene: 3177022 | Ensembl: ENSG000001806637 | UniProtKB: Q9BXE93 | | ORGUL members: | |
|---|
| NONCODE:n382971 | |
Export aliases for VN1R3 gene to outside databasesPrevious GC identifers: GC16M032315 GC16M031815 GC16M031855 GC16M031856 GC16M031726 GC16M029379
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Summaries
for VN1R3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: VN1R3_HUMAN, Q9BXE9Function: Putative pheromone receptor
Gene Wiki entry for VN1R3
|
Genomic Views
for VN1R3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for VN1R3
Other transcription factors
Search SABiosciences Chromatin IP Primers for VN1R3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VN1R3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2VN1R3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M031818: view genomic region
(about GC identifiers)
Start:
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31,818,911 bp from pter |
End:
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31,820,167 bp from pter |
Size:
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1,257 bases |
Orientation:
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minus strand |
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Proteins
for VN1R3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VN1R3_HUMAN, Q9BXE9 (See
protein sequence)Recommended Name: Vomeronasal type-1 receptor 3 Size: 311 amino acids; 34713 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: The gorilla and orangutan orthologous proteins do not exist, their genes are pseudogenesExplore the universe of human proteins at neXtProt for VN1R3: NX_Q9BXE9
VN1R3 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products for VN1R3:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
VN1R3 for ontologies About GeneDecksing
VN1R3 Antibody Products:
Assay Products for VN1R3: |
Protein
Domains /
Families
for VN1R3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VN1R3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BXE9ProtoNet protein and cluster: Q9BXE9 1 Blocks protein family: IPB004072 Vomeronasal type 1 receptor family signature
UniProtKB/Swiss-Prot: VN1R3_HUMAN, Q9BXE9Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for VN1R3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Molecular Function:
UniProtKB/Swiss-Prot Summary: VN1R3_HUMAN, Q9BXE9Function: Putative pheromone receptor Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016503 | pheromone receptor activity |
IEA | -- |
VN1R3 for ontologies About GeneDecksing
Animal Models:
|
Pathways & Interactions
for VN1R3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VN1R3
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019236 | response to pheromone |
IEA | -- |
VN1R3 for ontologies About GeneDecksing
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Drugs & Compounds
for VN1R3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VN1R3
Search CenterWatch for drugs/clinical trials and news about VN1R3 
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Transcripts
for VN1R3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for VN1R3: Vomeronasal 1 receptor 3 (gene/pseudogene) Hs.257746 [show with all ESTs]Unigene Representative Sequence: AF3368732 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000418822(uc002ecr.3) ENST00000316512
Additional cDNA sequence: AF336873.1 BC107073.1 BC107074.1 1 DOTS entry: DT.99944779 2 AceView cDNA sequences: AF336873 NM_174980
GeneLoc Exon Structure
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Expression
for VN1R3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VN1R3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCCGCCATC
About this image
Genevestigator expression for VN1R3
SOURCE GeneReport for Unigene cluster: Hs.257746
SABiosciences Custom PCR Arrays for VN1R3
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VN1R3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat VN1R3 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VN1R3 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VN1R3 |
Orthologs
for VN1R3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for VN1R3 gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Vmn1r2355 |
vomeronasal 1 receptor 235 |
-- |
|
17 (11.40 cM) 21260427 |
ENSEMBL Gene Tree for VN1R3 (if available)
TreeFam Gene Tree for VN1R3 (if available) |
Paralogs
for VN1R3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for VN1R3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: VN1R3_HUMAN, Q9BXE9Polymorphism: There seems to be a deletion in the gene coding for this protein in about 98% of the population
| SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for VN1R3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for VN1R3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VN1R3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with VN1R3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates. (PubMed id 12826614)1, 2 Zhang J. and Webb D.M. (2003)
- Novel human vomeronasal receptor-like genes reveal species-specific families. (PubMed id 12123587)1, 2 Rodriguez I. and Mombaerts P. (2002)
- Extreme variability among mammalian V1R gene families . (PubMed id 19952141)1 Young J.M....Trask B.J. (2010)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for VN1R3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing VN1R3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VN1R3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VN1R3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for VN1R3 | Pharmacogenomics, SNPs, Pathways | | Protein Spotlight | http://web.expasy.org/spotlight/back_issues/sptlt061.shtml |
|
| | |
About This Section
| Patent Information for VN1R3 gene:
Search GeneIP for patents involving VN1R3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VN1R3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for VN1R3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VN1R3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VN1R3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VN1R3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VN1R3 | | OriGene Custom Protein Services for VN1R3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VN1R3 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VN1R3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VN1R3 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VN1R3 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VN1R3 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VN1R3 |
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 |  |  |  | |
| | | | Search Tocris compounds for VN1R3 |
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 | | | VN1R3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | ThermoFisher Antibodies for VN1R3 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat VN1R3 |
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