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Aliases for VN1R1 Gene

Aliases for VN1R1 Gene

  • Vomeronasal 1 Receptor 1 2 3
  • V1RL1 3 4 6
  • Vomeronasal Olfactory Receptor, (Chromosome 19) Subtype I, Member 1 2 3
  • Vomeronasal Olfactory Receptor Chromosome 19 Subtype I Member 1 3 4
  • G-Protein Coupled Receptor GPCR24 3 4
  • V3r-Related Gene Protein 3 4
  • V1r-Like Receptor 1 3 4
  • VNR19I1 3 4
  • HGPCR24 3 4
  • Vomeronasal Type-1 Receptor 1 3
  • V1R-Like 1 3
  • ZVNH1 3
  • ZVNR1 3

External Ids for VN1R1 Gene

Previous Symbols for VN1R1 Gene

  • VNR19I1

Summaries for VN1R1 Gene

Entrez Gene Summary for VN1R1 Gene

  • Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

GeneCards Summary for VN1R1 Gene

VN1R1 (Vomeronasal 1 Receptor 1) is a Protein Coding gene. Among its related pathways are GPCRs, Other. GO annotations related to this gene include pheromone receptor activity. An important paralog of this gene is VN1R2.

UniProtKB/Swiss-Prot for VN1R1 Gene

  • Putative pheromone receptor

Gene Wiki entry for VN1R1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VN1R1 Gene

Genomics for VN1R1 Gene

Genomic Location for VN1R1 Gene

Start:
57,454,790 bp from pter
End:
57,457,142 bp from pter
Size:
2,353 bases
Orientation:
Minus strand

Genomic View for VN1R1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VN1R1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VN1R1 Gene

Regulatory Elements for VN1R1 Gene

Proteins for VN1R1 Gene

  • Protein details for VN1R1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZP7-VN1R1_HUMAN
    Recommended name:
    Vomeronasal type-1 receptor 1
    Protein Accession:
    Q9GZP7
    Secondary Accessions:
    • B3KSV5
    • Q7Z5H8
    • Q7Z5H9

    Protein attributes for VN1R1 Gene

    Size:
    353 amino acids
    Molecular mass:
    40021 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The chimpanzee and orangutan orthologous proteins do not exist, their genes are pseudogenes

neXtProt entry for VN1R1 Gene

Proteomics data for VN1R1 Gene at MOPED

Post-translational modifications for VN1R1 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn117 and Asn198

Other Protein References for VN1R1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VN1R1 Gene

Domains for VN1R1 Gene

Gene Families for VN1R1 Gene

HGNC:
  • VN1R :Vomeronasal receptors / Type 1
  • VN1RU :GPCR / Unclassified : Vomeronasal receptors, type 1

Protein Domains for VN1R1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

VN1R1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9GZP7
genes like me logo Genes that share domains with VN1R1: view

Function for VN1R1 Gene

Molecular function for VN1R1 Gene

UniProtKB/Swiss-Prot Function: Putative pheromone receptor

Gene Ontology (GO) - Molecular Function for VN1R1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity --
GO:0016503 pheromone receptor activity IEA --
genes like me logo Genes that share ontologies with VN1R1: view

Phenotypes for VN1R1 Gene

GenomeRNAi human phenotypes for VN1R1:
genes like me logo Genes that share phenotypes with VN1R1: view

miRNA for VN1R1 Gene

miRTarBase miRNAs that target VN1R1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for VN1R1 Gene

Localization for VN1R1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VN1R1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for VN1R1 Gene COMPARTMENTS Subcellular localization image for VN1R1 gene
Compartment Confidence
plasma membrane 5
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for VN1R1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with VN1R1: view

Pathways for VN1R1 Gene

SuperPathways for VN1R1 Gene

Superpath Contained pathways
1 GPCRs, Other
genes like me logo Genes that share pathways with VN1R1: view

Pathways by source for VN1R1 Gene

1 BioSystems pathway for VN1R1 Gene

Interacting Proteins for VN1R1 Gene

Gene Ontology (GO) - Biological Process for VN1R1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0008150 biological_process ND --
GO:0019236 response to pheromone IEA --
GO:0050909 sensory perception of taste --
genes like me logo Genes that share ontologies with VN1R1: view

Transcripts for VN1R1 Gene

mRNA/cDNA for VN1R1 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(74) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for VN1R1 Gene

Vomeronasal 1 receptor 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for VN1R1 Gene

No ASD Table

Relevant External Links for VN1R1 Gene

GeneLoc Exon Structure for
VN1R1
ECgene alternative splicing isoforms for
VN1R1

Expression for VN1R1 Gene

mRNA expression in normal human tissues for VN1R1 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for VN1R1 Gene

SOURCE GeneReport for Unigene cluster for VN1R1 Gene Hs.677423

mRNA Expression by UniProt/SwissProt for VN1R1 Gene

Q9GZP7-VN1R1_HUMAN
Tissue specificity: Expressed in the olfactory mucosa, very low expression in brain, lung and kidney.
genes like me logo Genes that share expressions with VN1R1: view

Orthologs for VN1R1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for VN1R1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia VN1R3 37
  • 47 (a)
OneToOne
cow
(Bos Taurus)
Mammalia VN1R1 36
  • 74.97 (n)
  • 62.14 (a)
VN1R1 37
  • 59 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Vmn1r70 16
Vmn1r83 37
  • 36 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 38 (a)
OneToMany
-- 37
  • 35 (a)
OneToMany
monDomV1R1221 37
  • 35 (a)
OneToMany
monDomV1R1223 37
  • 39 (a)
OneToMany
monDomV1R1224 37
  • 41 (a)
OneToMany
monDomV1R1225 37
  • 40 (a)
OneToMany
monDomV1R1228 37
  • 39 (a)
OneToMany
monDomV1R1230 37
  • 37 (a)
OneToMany
monDomV1R1231 37
  • 36 (a)
OneToMany
monDomV1R1232 37
  • 37 (a)
OneToMany
monDomV1R1233 37
  • 38 (a)
OneToMany
monDomV1R1234 37
  • 42 (a)
OneToMany
monDomV1R1235 37
  • 45 (a)
OneToMany
monDomV1R1236 37
  • 37 (a)
OneToMany
monDomV1R1238 37
  • 38 (a)
OneToMany
monDomV1R1239 37
  • 37 (a)
OneToMany
monDomV1R1242 37
  • 34 (a)
OneToMany
monDomV1R1243 37
  • 37 (a)
OneToMany
monDomV1R1244 37
  • 35 (a)
OneToMany
monDomV1R1245 37
  • 35 (a)
OneToMany
monDomV1R1246 37
  • 36 (a)
OneToMany
monDomV1R1254 37
  • 34 (a)
OneToMany
monDomV1R1256 37
  • 33 (a)
OneToMany
monDomV1R1257 37
  • 34 (a)
OneToMany
monDomV1R1258 37
  • 34 (a)
OneToMany
monDomV1R1259 37
  • 35 (a)
OneToMany
monDomV1R1260 37
  • 34 (a)
OneToMany
monDomV1R1261 37
  • 35 (a)
OneToMany
monDomV1R1263 37
  • 32 (a)
OneToMany
monDomV1R1266 37
  • 35 (a)
OneToMany
monDomV1R1267 37
  • 36 (a)
OneToMany
monDomV1R1268 37
  • 34 (a)
OneToMany
monDomV1R1270 37
  • 37 (a)
OneToMany
monDomV1R1271 37
  • 39 (a)
OneToMany
monDomV1R1272 37
  • 39 (a)
OneToMany
monDomV1R1280 37
  • 35 (a)
OneToMany
monDomV1R1281 37
  • 39 (a)
OneToMany
monDomV1R1282 37
  • 39 (a)
OneToMany
monDomV1R1283 37
  • 39 (a)
OneToMany
monDomV1R1290 37
  • 36 (a)
OneToMany
monDomV1R1292 37
  • 36 (a)
OneToMany
monDomV1R1294 37
  • 37 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Vom1r52 36
  • 62.58 (n)
  • 45.7 (a)
Species with no ortholog for VN1R1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for VN1R1 Gene

ENSEMBL:
Gene Tree for VN1R1 (if available)
TreeFam:
Gene Tree for VN1R1 (if available)

Paralogs for VN1R1 Gene

Paralogs for VN1R1 Gene

Selected SIMAP similar genes for VN1R1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with VN1R1: view

Variants for VN1R1 Gene

Sequence variations from dbSNP and Humsavar for VN1R1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3746223 - 57,456,178(-) GGGAT(A/G)CCTCA reference, missense
rs6510072 -- 57,458,609(+) TTTAT(C/T)TTCAA upstream-variant-2KB
rs7247474 -- 57,455,094(+) AAGCA(A/C)CTGAA downstream-variant-500B
rs8101158 -- 57,454,712(+) cccac(A/C)tcagc downstream-variant-500B
rs8109760 -- 57,457,182(+) GCCCT(C/T)CAGCC upstream-variant-2KB

Relevant External Links for VN1R1 Gene

HapMap Linkage Disequilibrium report
VN1R1

No data available for Structural Variations from Database of Genomic Variants (DGV) for VN1R1 Gene

Disorders for VN1R1 Gene

Relevant External Links for VN1R1

Genetic Association Database (GAD)
VN1R1
Human Genome Epidemiology (HuGE) Navigator
VN1R1
genes like me logo Genes that share disorders with VN1R1: view

No data available for UniProtKB/Swiss-Prot for VN1R1 Gene

Publications for VN1R1 Gene

  1. A putative pheromone receptor gene expressed in human olfactory mucosa. (PMID: 10973240) Rodriguez I. … Mombaerts P. (Nat. Genet. 2000) 2 3 4
  2. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 3 4
  3. Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates. (PMID: 12826614) Zhang J. … Webb D.M. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for VN1R1 Gene

Sources for VN1R1 Gene

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