Aliases for VMO1 Gene
Aliases for VMO1 Gene
External Ids for VMO1 Gene
- HGNC: 30387
- Entrez Gene: 284013
- Ensembl: ENSG00000182853
- UniProtKB: Q7Z5L0
Previous GeneCards Identifiers for VMO1 Gene
- GC17M004636
- GC17M004688
- GC17M004576
Summaries for VMO1 Gene
GeneCards Summary for VMO1 Gene
VMO1 (Vitelline Membrane Outer Layer 1 Homolog) is a Protein Coding gene.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VMO1 Gene
Genomics for VMO1 Gene
Regulatory Elements for VMO1 Gene
Enhancers for VMO1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around VMO1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the VMO1 gene promoter:
Regulatory Element Products
Genomic Location for VMO1 Gene
- Chromosome:
- 17
- Start:
- 4,785,285 bp from pter
- End:
- 4,786,434 bp from pter
- Size:
- 1,150 bases
- Orientation:
- Minus strand
Genomic View for VMO1 Gene
Genes around VMO1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17p13.2 by Ensembl
- 17p13.2 by Entrez Gene
- 17p13.2 by HGNC
VMO1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for VMO1 Gene
Proteins for VMO1 Gene
-
Protein details for VMO1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z5L0-VMO1_HUMAN
- Recommended name:
- Vitelline membrane outer layer protein 1 homolog
- Protein Accession:
- Q7Z5L0
- C9JQ15
- E9PAU9
- E9PGP4
- Q3SXP1
- Q8IUY1
Protein attributes for VMO1 Gene
- Size:
- 202 amino acids
- Molecular mass:
- 21534 Da
- Quaternary structure:
- No Data Available
Protein Expression for VMO1 Gene
Post-translational modifications for VMO1 Gene
Other Protein References for VMO1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for VMO1
-
Abcam antibodies for VMO1
- Invitrogen Antibodies for VMO1
- GeneTex VMO1 antibody for VMO1
Protein Products
-
OriGene Purified Proteins for VMO1
- Search Origene for MassSpec and Protein Over-expression Lysates for VMO1
- Origene Custom Protein Services for VMO1
- Sino Biological Cell Lysates for VMO1
- Sino Biological Recombinant Proteins for VMO1
- Search GeneTex for Proteins for VMO1
-
Abcam proteins for VMO1
Assay Products
No data available for DME Specific Peptides for VMO1 Gene
Domains & Families for VMO1 Gene
Suggested Antigen Peptide Sequences for VMO1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q7Z5L0- Family:
-
- Belongs to the VMO1 family.
No data available for Gene Families for VMO1 Gene
Function for VMO1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for VMO1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for VMO1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for VMO1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for VMO1 gene
- Search ViGene Biosciences for VMO1
CRISPR Products
-
OriGene CRISPR knockouts for VMO1
- GenScript: Design CRISPR guide RNA sequences for VMO1
miRNA for VMO1 Gene
- miRTarBase miRNAs that target VMO1
miRNA Products
- Search ViGene Biosciences for VMO1
Inhibitory RNA Products
- Origene mouse_rna, siRNA, shRNA, and RNAi products in human, mouse, rat for VMO1
- Browse OriGene Inhibitory RNA Products For VMO1
-
ViGene Biosciences ready-to-package AAV shRNAs for VMO1 gene
Clone Products
- Sino Biological Human cDNA Clone for VMO1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for VMO1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for VMO1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for VMO1
-
ViGene Biosciences adenoviral particle packaged cDNA for VMO1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for VMO1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for VMO1 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for VMO1 Gene
Localization for VMO1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for VMO1 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0070062 | extracellular exosome | IDA | 19056867 |
Pathways & Interactions for VMO1 Gene
No Data Available
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for VMO1 Gene
Transcripts for VMO1 Gene
mRNA/cDNA for VMO1 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (34) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for VMO1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for VMO1
- GenScript: Design CRISPR guide RNA sequences for VMO1
miRNA Products
- Search ViGene Biosciences for VMO1
Inhibitory RNA Products
- Origene mouse_rna, siRNA, shRNA, and RNAi products in human, mouse, rat for VMO1
- Browse OriGene Inhibitory RNA Products For VMO1
-
ViGene Biosciences ready-to-package AAV shRNAs for VMO1 gene
Clone Products
- Sino Biological Human cDNA Clone for VMO1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for VMO1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for VMO1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||
| SP2: | |||||||||
| SP3: | - | - |
Expression for VMO1 Gene
mRNA differential expression in normal tissues according to GTEx for VMO1 Gene
This gene is overexpressed in Spleen (x7.3) and Pituitary (x7.1).
This gene is overexpressed in Urine (60.1) and Nasal epithelium (6.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for VMO1 Gene
NURSA nuclear receptor signaling pathways regulating expression of VMO1 Gene:
VMO1SOURCE GeneReport for Unigene cluster for VMO1 Gene:
Hs.122561Primer Products
-
OriGene qPCR primer pairs for VMO1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for VMO1 Gene
Orthologs for VMO1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | VMO1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | VMO1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Vmo1 34 |
|
||
| dog (Canis familiaris) |
Mammalia | VMO1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Vmo1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | VMO1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | VMO1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | VMO1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | VMO1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC101731130 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC793369 34 |
|
||
| VMO1 (1 of 2) 35 |
|
OneToMany | |||
| VMO1 (2 of 2) 35 |
|
OneToMany | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.804 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | Y38H6C.19 35 |
|
OneToMany | |
| F46F5.13 35 |
|
OneToMany | |||
| F28A10.8 35 |
|
OneToMany | |||
| T02H6.9 35 |
|
OneToMany | |||
| Y54E2A.9 35 |
|
OneToMany | |||
| K07E8.1 35 |
|
OneToMany | |||
| C47A10.12 35 |
|
OneToMany | |||
| Y40B10B.1 35 |
|
OneToMany | |||
| Y9C9A.1 35 |
|
OneToMany | |||
| Y39F10C.1 35 |
|
OneToMany | |||
| C08G5.3 35 |
|
OneToMany | |||
| Y57G11A.2 35 |
|
OneToMany |
- Species where no ortholog for VMO1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for VMO1 Gene
No data available for Paralogs for VMO1 Gene
Variants for VMO1 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs111749791 | -- | 4,785,985(+) | TCCCG(C/G/T)GCGCG | intron-variant, reference, missense | |
| rs111913196 | -- | 4,785,224(+) | GCGAT(A/T)CTCCG | downstream-variant-500B | |
| rs114217769 | -- | 4,785,305(+) | TTTAA(C/T)AGCAA | utr-variant-3-prime | |
| rs115427152 | -- | 4,785,246(+) | TAAAT(A/T)AATAA | downstream-variant-500B | |
| rs116393799 | -- | 4,785,856(+) | GCCAG(C/G/T)CTGCC | intron-variant |
Residual Variation Intolerance Score:
42.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.02;
68.54% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for VMO1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- VMO1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VMO1 Gene
Disorders for VMO1 Gene
Relevant External Links for VMO1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- VMO1
No disorders were found for VMO1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for VMO1 Gene
Publications for VMO1 Gene
- Analysis and comparison of proteomic profiles of tear fluid from human, cow, sheep, and camel eyes. (PMID: 22025569) Shamsi F.A. … Wu K. (Invest. Ophthalmol. Vis. Sci. 2011) 2 3 64
- Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4 64
- Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3 64
Products for VMO1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for VMO1
- Search Origene for MassSpec and Protein Over-expression Lysates for VMO1
- Origene Custom Protein Services for VMO1
- Origene mouse_rna, siRNA, shRNA, and RNAi products in human, mouse, rat for VMO1
- Browse OriGene Inhibitory RNA Products For VMO1
- OriGene qPCR primer pairs for VMO1
- OriGene CRISPR knockouts for VMO1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For VMO1
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for VMO1
- GenScript Custom Assay Services for VMO1
- GenScript Custom overexpressing Cell Line Services for VMO1
- GenScript: Design CRISPR guide RNA sequences for VMO1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for VMO1
- Sino Biological Human cDNA Clone for VMO1
- Sino Biological Cell Lysates for VMO1
- Sino Biological Recombinant Proteins for VMO1
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for VMO1
- Novus Biologicals proteins and lysates for VMO1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for VMO1
- Abcam proteins for VMO1
- Search for Assays for VMO1 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ViGene Biosciences adenoviral particle packaged cDNA for VMO1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for VMO1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for VMO1 gene
- Search ViGene Biosciences for VMO1
- Horizon Cell Lines for VMO1
- Cyagen custom Knockout/knockin (KOKI) mouse models for VMO1
- VectorBuilder custom plasmid, inducible vectors for VMO1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for VMO1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for VMO1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab