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Aliases for VMO1 Gene

Aliases for VMO1 Gene

  • Vitelline Membrane Outer Layer 1 Homolog (Chicken) 2 3
  • Vitelline Membrane Outer Layer Protein 1 Homolog 3
  • ERGA6350 3
  • PRO21055 3

External Ids for VMO1 Gene

Previous GeneCards Identifiers for VMO1 Gene

  • GC17M004636
  • GC17M004688
  • GC17M004576

Summaries for VMO1 Gene

GeneCards Summary for VMO1 Gene

VMO1 (Vitelline Membrane Outer Layer 1 Homolog (Chicken)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VMO1 Gene

Genomics for VMO1 Gene

Regulatory Elements for VMO1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for VMO1 Gene

Start:
4,785,285 bp from pter
End:
4,786,434 bp from pter
Size:
1,150 bases
Orientation:
Minus strand

Genomic View for VMO1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VMO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VMO1 Gene

Proteins for VMO1 Gene

  • Protein details for VMO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z5L0-VMO1_HUMAN
    Recommended name:
    Vitelline membrane outer layer protein 1 homolog
    Protein Accession:
    Q7Z5L0
    Secondary Accessions:
    • C9JQ15
    • E9PAU9
    • E9PGP4
    • Q3SXP1
    • Q8IUY1

    Protein attributes for VMO1 Gene

    Size:
    202 amino acids
    Molecular mass:
    21534 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for VMO1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for VMO1 Gene

Proteomics data for VMO1 Gene at MOPED

Post-translational modifications for VMO1 Gene

No Post-translational modifications

Other Protein References for VMO1 Gene

No data available for DME Specific Peptides for VMO1 Gene

Domains for VMO1 Gene

Protein Domains for VMO1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for VMO1 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z5L0

UniProtKB/Swiss-Prot:

VMO1_HUMAN :
  • Q7Z5L0
Family:
  • Belongs to the VMO1 family.
genes like me logo Genes that share domains with VMO1: view

No data available for Gene Families for VMO1 Gene

Function for VMO1 Gene

Gene Ontology (GO) - Molecular Function for VMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with VMO1: view

Phenotypes for VMO1 Gene

genes like me logo Genes that share phenotypes with VMO1: view

Animal Model Products

CRISPR Products

miRNA for VMO1 Gene

miRTarBase miRNAs that target VMO1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VMO1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for VMO1 Gene

Localization for VMO1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for VMO1 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for VMO1 Gene COMPARTMENTS Subcellular localization image for VMO1 gene
Compartment Confidence
extracellular 4
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for VMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with VMO1: view

Pathways for VMO1 Gene

SuperPathways for VMO1 Gene

No Data Available

Interacting Proteins for VMO1 Gene

Gene Ontology (GO) - Biological Process for VMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with VMO1: view

No data available for Pathways by source for VMO1 Gene

Transcripts for VMO1 Gene

Unigene Clusters for VMO1 Gene

Vitelline membrane outer layer 1 homolog (chicken):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VMO1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for VMO1
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VMO1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2:
SP3: - -

Relevant External Links for VMO1 Gene

GeneLoc Exon Structure for
VMO1
ECgene alternative splicing isoforms for
VMO1

Expression for VMO1 Gene

mRNA expression in normal human tissues for VMO1 Gene

mRNA differential expression in normal tissues according to GTEx for VMO1 Gene

This gene is overexpressed in Spleen (7.3) and Pituitary (7.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for VMO1 Gene

SOURCE GeneReport for Unigene cluster for VMO1 Gene Hs.122561

genes like me logo Genes that share expressions with VMO1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for VMO1 Gene

Orthologs for VMO1 Gene

This gene was present in the common ancestor of animals.

Orthologs for VMO1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia VMO1 35
  • 99.17 (n)
  • 98.02 (a)
VMO1 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia VMO1 35
  • 82.08 (n)
  • 78.89 (a)
VMO1 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia VMO1 35
  • 78.11 (n)
  • 76.62 (a)
VMO1 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Vmo1 35
  • 73.3 (n)
  • 71.64 (a)
Vmo1 16
Vmo1 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia VMO1 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia VMO1 36
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Vmo1 35
  • 78.56 (n)
  • 78.95 (a)
chicken
(Gallus gallus)
Aves VMO1 35
  • 58.28 (n)
  • 59.12 (a)
VMO1 36
  • 53 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia VMO1 36
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731130 35
  • 57.37 (n)
  • 56.97 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.804 35
zebrafish
(Danio rerio)
Actinopterygii LOC793369 35
  • 54.27 (n)
  • 53.66 (a)
VMO1 (1 of 2) 36
  • 47 (a)
OneToMany
VMO1 (2 of 2) 36
  • 43 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C08G5.3 36
  • 12 (a)
OneToMany
C47A10.12 36
  • 21 (a)
OneToMany
F28A10.8 36
  • 29 (a)
OneToMany
F46F5.13 36
  • 30 (a)
OneToMany
K07E8.1 36
  • 28 (a)
OneToMany
T02H6.9 36
  • 29 (a)
OneToMany
Y38H6C.19 36
  • 36 (a)
OneToMany
Y39F10C.1 36
  • 18 (a)
OneToMany
Y40B10B.1 36
  • 19 (a)
OneToMany
Y54E2A.9 36
  • 29 (a)
OneToMany
Y57G11A.2 36
  • 8 (a)
OneToMany
Y9C9A.1 36
  • 19 (a)
OneToMany
Species with no ortholog for VMO1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for VMO1 Gene

ENSEMBL:
Gene Tree for VMO1 (if available)
TreeFam:
Gene Tree for VMO1 (if available)

Paralogs for VMO1 Gene

No data available for Paralogs for VMO1 Gene

Variants for VMO1 Gene

Sequence variations from dbSNP and Humsavar for VMO1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2279961 - 4,786,018(-) CGACA(C/G)TGCAC reference, missense, intron-variant
rs2279962 -- 4,785,701(-) GTGAA(G/T)GGGGG intron-variant
rs3215170 -- 4,785,900(-) TGATG(-/G)TATGT splice-donor-variant, intron-variant
rs4790706 - 4,786,277(+) ATCTG(C/T)CTGTG reference, missense
rs55992208 -- 4,785,246(+) TAAAT(-/TAATAAATAAAT)AAATG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for VMO1 Gene

Variant ID Type Subtype PubMed ID
nsv833346 CNV Loss 17160897
nsv907618 CNV Loss 21882294
nsv833347 CNV Loss 17160897

Relevant External Links for VMO1 Gene

HapMap Linkage Disequilibrium report
VMO1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VMO1 Gene

Disorders for VMO1 Gene

No disorders were found for VMO1 Gene.

No data available for UniProtKB/Swiss-Prot for VMO1 Gene

Publications for VMO1 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Analysis and comparison of proteomic profiles of tear fluid from human, cow, sheep, and camel eyes. (PMID: 22025569) Shamsi F.A. … Wu K. (Invest. Ophthalmol. Vis. Sci. 2011) 2 3
  5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for VMO1 Gene

Sources for VMO1 Gene

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