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Aliases for VMAC Gene

Aliases for VMAC Gene

  • Vimentin-Type Intermediate Filament Associated Coiled-Coil Protein 2 3

External Ids for VMAC Gene

Previous GeneCards Identifiers for VMAC Gene

  • GC19P005855
  • GC19P005664

Summaries for VMAC Gene

GeneCards Summary for VMAC Gene

VMAC (Vimentin-Type Intermediate Filament Associated Coiled-Coil Protein) is a Protein Coding gene. An important paralog of this gene is ENSG00000267314.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for VMAC Gene

Genomics for VMAC Gene

Regulatory Elements for VMAC Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for VMAC Gene

Start:
5,904,841 bp from pter
End:
5,910,853 bp from pter
Size:
6,013 bases
Orientation:
Plus strand

Genomic View for VMAC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for VMAC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for VMAC Gene

Proteins for VMAC Gene

  • Protein details for VMAC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2NL98-VMAC_HUMAN
    Recommended name:
    Vimentin-type intermediate filament-associated coiled-coil protein
    Protein Accession:
    Q2NL98
    Secondary Accessions:
    • B3KW55

    Protein attributes for VMAC Gene

    Size:
    169 amino acids
    Molecular mass:
    18348 Da
    Quaternary structure:
    No Data Available

neXtProt entry for VMAC Gene

Proteomics data for VMAC Gene at MOPED

Post-translational modifications for VMAC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for VMAC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for VMAC Gene

Domains for VMAC Gene

Protein Domains for VMAC Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with VMAC: view

No data available for Gene Families and UniProtKB/Swiss-Prot for VMAC Gene

Function for VMAC Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for VMAC Gene

Localization for VMAC Gene

Subcellular locations from UniProtKB/Swiss-Prot for VMAC Gene

Cytoplasm. Note=Colocalizes with vimentin-type intermediate filaments. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for VMAC Gene COMPARTMENTS Subcellular localization image for VMAC gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for VMAC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with VMAC: view

Pathways for VMAC Gene

SuperPathways for VMAC Gene

No Data Available

Interacting Proteins for VMAC Gene

Selected Interacting proteins: Q2NL98-VMAC_HUMAN for VMAC Gene via I2D

Symbol External ID(s) Details
DLG4
ESR2

Gene Ontology (GO) - Biological Process for VMAC Gene

None

No data available for Pathways by source for VMAC Gene

Transcripts for VMAC Gene

mRNA/cDNA for VMAC Gene

(186) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for VMAC Gene

Vimentin-type intermediate filament associated coiled-coil protein:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for VMAC

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for VMAC Gene

No ASD Table

Relevant External Links for VMAC Gene

GeneLoc Exon Structure for
VMAC
ECgene alternative splicing isoforms for
VMAC

Expression for VMAC Gene

mRNA expression in normal human tissues for VMAC Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for VMAC Gene

SOURCE GeneReport for Unigene cluster for VMAC Gene Hs.620821

genes like me logo Genes that share expressions with VMAC: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for VMAC Gene

Orthologs for VMAC Gene

This gene was present in the common ancestor of chordates.

Orthologs for VMAC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia VMAC 35
  • 99.61 (n)
  • 99.41 (a)
VMAC 36
  • 99 (a)
OneToMany
cow
(Bos Taurus)
Mammalia VMAC 35
  • 86.35 (n)
  • 82.53 (a)
VMAC 36
  • 83 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 89 (a)
OneToMany
VMAC 35
  • 89.74 (n)
  • 89.35 (a)
mouse
(Mus musculus)
Mammalia Vmac 35
  • 78.9 (n)
  • 76.33 (a)
Vmac 16
Vmac 36
  • 74 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 54 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Vmac 35
  • 79.49 (n)
  • 75.74 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC570934 35
  • 57.79 (n)
  • 49.7 (a)
VMAC 36
  • 46 (a)
OneToMany
Species with no ortholog for VMAC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for VMAC Gene

ENSEMBL:
Gene Tree for VMAC (if available)
TreeFam:
Gene Tree for VMAC (if available)

Paralogs for VMAC Gene

Paralogs for VMAC Gene

genes like me logo Genes that share paralogs with VMAC: view

Variants for VMAC Gene

Sequence variations from dbSNP and Humsavar for VMAC Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs386803 -- 5,907,394(+) acgtg(G/T)tgtgg intron-variant
rs416676 -- 5,907,347(+) tgtgt(C/T)tccac intron-variant
rs417337 -- 5,907,570(+) gaatt(C/T)gagac intron-variant
rs420458 -- 5,909,769(-) CTTAC(A/G)CCTAT utr-variant-3-prime
rs432990 -- 5,907,538(-) gcttc(A/G)gcctc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for VMAC Gene

Variant ID Type Subtype PubMed ID
dgv3693n71 CNV Loss 21882294
nsv910904 CNV Loss 21882294
nsv910905 CNV Loss 21882294
nsv910906 CNV Loss 21882294
nsv910907 CNV Loss 21882294
esv27099 CNV Loss 19812545

Relevant External Links for VMAC Gene

HapMap Linkage Disequilibrium report
VMAC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for VMAC Gene

Disorders for VMAC Gene

No disorders were found for VMAC Gene.

No data available for UniProtKB/Swiss-Prot for VMAC Gene

Publications for VMAC Gene

  1. Vmac: a novel protein associated with vimentin-type intermediate filament in podocytes of rat kidney. (PMID: 14985129) Yamamoto Y. … Takai Y. (Biochem. Biophys. Res. Commun. 2004) 2 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for VMAC Gene

Sources for VMAC Gene

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