Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



VIT Gene

protein-coding   GIFtS: 51
GCID: GC02P036835

Vitrin

  Search for VIT
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
vitrin1 2
DDVIT15
EDPF15
MMS25
UBE2V25
UEV25

External Ids:    HGNC: 126971   Entrez Gene: 52122   Ensembl: ENSG000002052217   OMIM: 6030015   UniProtKB: Q6UXI73   

Export aliases for VIT gene to outside databases

Previous GC identifers: GC02P036888 GC02P037070 GC02P036898 GC02P036664


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for VIT Gene:
VIT (vitrin) is a protein-coding gene. GO annotations related to this gene include glycosaminoglycan binding. An important paralog of this gene is VWA1.

UniProtKB/Swiss-Prot: VITRN_HUMAN, Q6UXI7
Function: Promotes matrix assembly and cell adhesiveness (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VIT gene promoter:
         STAT5B   STAT1   AML1a   STAT4   STAT6   STAT1beta   STAT5A   STAT1alpha   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVIT promoter sequence
   Search Chromatin IP Primers for VIT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VIT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p22.2   Ensembl cytogenetic band:  2p22.2   HGNC cytogenetic band: 2p22.2

VIT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VIT gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P036835:  view genomic region     (about GC identifiers)

Start:
36,923,833 bp from pter      End:
37,041,937 bp from pter
Size:
118,105 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: VITRN_HUMAN, Q6UXI7 (See protein sequence)
Recommended Name: Vitrin precursor  
Size: 678 amino acids; 73930 Da
Subunit: Binds dermatan sulfate and chondroitin sulfate (By similarity)
Secondary accessions: A1A526 A6NKI9 A8K7Y4 E9PF47 Q6P7T3 Q96DM8 Q96DT1 Q9UDN0
Alternative splicing: 5 isoforms:  Q6UXI7-1   Q6UXI7-2   Q6UXI7-3   Q6UXI7-4   Q6UXI7-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VIT: NX_Q6UXI7

Explore proteomics data for VIT at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn390, Asn520
  • Modification sites at PhosphoSitePlus

  • See VIT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001171440.1  NP_001171441.1  NP_001171442.1  NP_001171443.1  NP_444506.2  

    ENSEMBL proteins: 
     ENSP00000368544   ENSP00000393561   ENSP00000417874   ENSP00000384154   ENSP00000368543  
     ENSP00000385658   ENSP00000419251   ENSP00000374625  

    VIT Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for VIT
    OriGene Custom MassSpec
    OriGene Custom Protein Services for VIT
    GenScript Custom Purified and Recombinant Proteins Services for VIT
    Novus Biologicals VIT Protein
    Novus Biologicals VIT Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for VIT

     
    Search eBioscience for Proteins for VIT 

    VIT Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for VIT
    Novus Biologicals VIT Antibody
    Abcam antibodies for VIT
    Cloud-Clone Corp. Antibodies for VIT
    ThermoFisher Antibodies for VIT
    LSBio Antibodies in human, mouse, rat for VIT

    VIT Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for VIT
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for VIT
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for VIT
    Cloud-Clone Corp. CLIAs for VIT
    Search eBioscience for ELISAs for VIT 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR004043 LCCL
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry Q6UXI7

    ProtoNet protein and cluster: Q6UXI7

    1 Blocks protein domain: IPB004043 LCCL domain

    UniProtKB/Swiss-Prot: VITRN_HUMAN, Q6UXI7
    Similarity: Contains 1 LCCL domain
    Similarity: Contains 2 VWFA domains


    Find genes that share domains with VIT           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VITRN_HUMAN, Q6UXI7
    Function: Promotes matrix assembly and cell adhesiveness (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005539glycosaminoglycan binding IEA--
         
    Find genes that share ontologies with VIT           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for VIT:
     Increased gamma-H2AX phosphory  Proliferating cells 

         1 MGI phenotypic allele for Vit (no phenotypes)

    Find genes that share phenotypes with VIT           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Vittm1Lex for VIT

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VIT
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VIT

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VIT
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VIT

    miRNA
    Products:
        
    miRTarBase miRNAs that target VIT:
    hsa-mir-124-3p (MIRT022689)

    Block miRNA regulation of human, mouse, rat VIT using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate VIT:
    hsa-miR-221* hsa-miR-425 hsa-miR-3662 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidVIT 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for VIT
    Predesigned siRNA for gene silencing in human, mouse, rat VIT

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for VIT

    Clone
    Products:
         
    OriGene clones in human, mouse for VIT (see all 24)
    OriGene ORF clones in mouse, rat for VIT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): VIT (NM_053276)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VIT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VIT

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for VIT
    Browse ESI BIO Cell Lines and PureStem Progenitors for VIT 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VIT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    VITRN_HUMAN, Q6UXI7: Secreted, extracellular space, extracellular matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum2
    extracellular2
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005614interstitial matrix IEA--
    GO:0031012extracellular matrix ----

    Find genes that share ontologies with VIT           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for VIT
        Ubiquitin-Proteasome Dependent Proteolysis
    Remodeling of Adherens Junctions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VIT
    Interactions:

        Search GeneGlobe Interaction Network for VIT

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010811positive regulation of cell-substrate adhesion IEA--
    GO:0030198extracellular matrix organization IEA--

    Find genes that share ontologies with VIT           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VIT (VITRN)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for VIT gene (5 alternative transcripts): 
    NM_001177969.1  NM_001177970.1  NM_001177971.1  NM_001177972.1  NM_053276.3  

    Unigene Cluster for VIT:

    Vitrin
    Hs.137415  [show with all ESTs]
    Unigene Representative Sequence: NM_053276
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379242(uc002rpl.3) ENST00000457137(uc002rpk.3) ENST00000497382
    ENST00000404084 ENST00000379241 ENST00000401530 ENST00000464309 ENST00000389975(uc010ynf.2 uc002rpm.3 uc010ezv.3 uc010ezw.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat VIT using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate VIT:
    hsa-miR-221* hsa-miR-425 hsa-miR-3662 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidVIT 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for VIT
    Predesigned siRNA for gene silencing in human, mouse, rat VIT
    Clone
    Products:
         
    OriGene clones in human, mouse for VIT (see all 24)
    OriGene ORF clones in mouse, rat for VIT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): VIT (NM_053276)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VIT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VIT
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for VIT
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VIT
      QuantiTect SYBR Green Assays in human, mouse, rat VIT
      QuantiFast Probe-based Assays in human, mouse, rat VIT

    Additional mRNA sequence: 

    AF063833.1 AK056772.1 AK292149.1 AK299426.1 AL832679.1 AY358338.1 BC061519.1 BC128260.1 

    7 DOTS entries:

    DT.437920  DT.40316582  DT.100736925  DT.100746868  DT.100023037  DT.97811644  DT.99976703 

    Selected AceView cDNA sequences (see all 56):

    AK056772 AA346825 BF726449 AW316554 NM_053276 AA687616 BM712204 BF726421 
    AL832679 CD679226 BX099804 AY358338 BM700057 BF727228 BU737859 BM700383 
    BM670265 AA227978 BF037138 CA421947 BF589678 CD516878 AI817458 BE612449 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    VIT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCACAGAAA
    VIT Expression
    About this image


    VIT expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 5 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Endothelial Cells Blood Brain Barrier
             Medulla Oblongata
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Neural Crest (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor
     
     Mesoderm (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor
    VIT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VIT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.137415
        Custom PCR Arrays for VIT
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for VIT
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VIT
    QuantiTect SYBR Green Assays in human, mouse, rat VIT
    QuantiFast Probe-based Assays in human, mouse, rat VIT
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VIT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for VIT gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vit1 , 5 vitrin1, 5 85.18(n)1
    84.77(a)1
      17 (49.38 cM)5
    741991  NM_028813.21  NP_083089.11 
     785080635 
    chicken
    (Gallus gallus)
    Aves VIT1 vitrin 71.14(n)
    68.44(a)
      421471  NM_001024580.1  NP_001019751.1 
    lizard
    (Anolis carolinensis)
    Reptilia VIT6
    vitrin
    62(a)
    1 ↔ 1
    1(232744807-232782615)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX735553.12   -- 74.26(n)    BX735553.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ch1073-291c23.11 ch1073-291c23.1 64.17(n)
    62.08(a)
      497398  XM_005156481.1  XP_005156538.1 


    ENSEMBL Gene Tree for VIT (if available)
    TreeFam Gene Tree for VIT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for VIT gene
    VWA12  MATN42  COL14A12  MATN32  MATN22  COL12A12  COCH2  COL20A12  
    VWA22  MATN12  
    5 SIMAP similar genes for VIT using alignment to 4 protein entries:     VITRN_HUMAN (see all proteins):
    ITGA2    COL21A1    COCH    COL6A6    COL6A5

    Find genes that share paralogs with VIT           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for VIT (see all 3100)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs106241191,2
    C--36921956(+) CTAGC-/ATT/  
      ATTATT
    attat
    10 -- cds11NA 2
    rs1996025491,2
    C--36922148(+) TATTT-/TGG   
      TAGAGA
    GGTAG
    5 -- us2k10--------
    rs3686779671,2
    C--36922151(+) tttgg-/TAG   
      AGATGG
    ggttt
    5 -- us2k10--------
    rs43463621,2
    --36922167(+) TTTCAC/GCATGT 5 -- us2k10--------
    rs1500015181,2
    C--36922264(+) GAGTCC/TAGCAG 5 -- us2k10--------
    rs1930177821,2
    C--36922292(+) TTAGGA/GATAAT 5 -- us2k10--------
    rs1452016831,2
    --36922436(+) AAAGAG/TGATTG 5 -- us2k10--------
    rs118997171,2
    C,F,A,H--36922541(+) CTTTAA/TTGGAG 5 -- us2k18Minor allele frequency- T:0.19NA WA CSA EA 368
    rs67076371,2
    C,A,H--36922547(+) TGGAGC/GAAGAT 5 -- us2k112Minor allele frequency- G:0.06NA WA CSA 256
    rs1856959121,2
    --36922622(+) ATCTAC/GATAGC 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for VIT (36923833 - 37041937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for VIT (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719924CNV Deletion23290073
    esv2668900CNV Deletion23128226
    nsv820661CNV Deletion20802225
    esv1427533CNV Deletion17803354
    dgv694e199CNV Deletion23128226
    esv1722218CNV Insertion17803354
    esv9230CNV Loss19470904
    nsv525132CNV Loss19592680
    nsv828920CNV Loss20364138
    nsv2682CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing VIT
    DNA2.0 Custom Variant and Variant Library Synthesis for VIT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 603001    OMIM disorders: --

    2 diseases from the University of Copenhagen DISEASES database for VIT:
    Hypersensitivity reaction type I disease     Mastocytosis

    Find genes that share disorders with VIT           About GenesLikeMe

    Genetic Association Database (GAD): VIT
    Human Genome Epidemiology (HuGE) Navigator: VIT (4 documents)

    Export disorders for VIT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for VIT gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with VIT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. VIT-1: the second member of a new branch of the von Willebrand factor A domain superfamily. (PubMed id 10830112)1, 2 Mayne R.... Narayana S. (Biochem. Soc. Trans. 1999)
    6. Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. (PubMed id 12388743)1, 9 Whittaker C.A. and Hynes R.O. (Mol. Biol. Cell 2002)
    7. Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin. (PubMed id 19729612)4 Paterson A.D....Bull S.B. (Arterioscler. Thromb. Vasc. Biol. 2009)
    8. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (BMC Med. Genet. 2007)
    9. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    10. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 5212 HGNC: 12697 AceView: VIT Ensembl:ENSG00000205221 euGenes: HUgn5212
    ECgene: VIT H-InvDB: VIT

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for VIT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for VIT gene:
    Search GeneIP for patents involving VIT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for VIT  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for VIT  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for VIT  
     OriGene qSTAR qPCR primer pairs in human, mouse for VIT   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for VIT   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for VIT   OriGene Custom Protein Services for VIT  

     
     
     Block miRNA regulation of human, mouse, rat VIT using miScript Target Protectors SeqTarget long-range PCR primers for resequencing VIT
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VIT Predesigned siRNA for gene silencing in human, mouse, rat VIT
     QuantiFast Probe-based Assays in human, mouse, rat VIT QuantiTect SYBR Green Assays in human, mouse, rat VIT
     Custom PCR Arrays for VIT Search Chromatin IP Primers for VIT
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VIT  Search GeneGlobe Interaction Network for VIT
     Regulatory tfbs in VIT promoter
     GenScript Custom Purified and Recombinant Proteins Services for VIT GenScript cDNA clones with any tag delivered in your preferred vector for VIT
     GenScript Custom Assay Services for VIT GenScript Custom overexpressing Cell Line Services for VIT
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for VIT (VITRN)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     VIT antibodies
     VIT proteins
     VIT lysates
     Antibodies for VIT
     See all of Abcam's Antibodies, Kits and Proteins for VIT
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for VIT
     Antibodies for VIT
     ELISAs for VIT
     CLIAs for VIT



     Browse ESI BIO Cell Lines and PureStem Progenitors for VIT
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VIT
     SwitchGear 3'UTR luciferase reporter plasmids for VIT
     SwitchGear Promoter luciferase reporter plasmids for VIT
     ThermoFisher Antibodies for VIT
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VIT
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VIT
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VIT
     LSBio Antibodies in human, mouse, rat for VIT
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for VIT
      Search eBioscience for proteins for VIT
      Search eBioscience for elisas for VIT
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      VIT gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4