Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



VILL Gene

protein-coding   GIFtS: 50
GCID: GC03P038029

Villin-Like

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
villin-like1 2
Villin-Like Protein2
EC 2.2.1.28
EC 6.3.2.68

External Ids:    HGNC: 309061   Entrez Gene: 508532   Ensembl: ENSG000001360597   UniProtKB: O151953   

Export aliases for VILL gene to outside databases

Previous GC identifers: GC03P037339 GC03P037845 GC03P037997 GC03P038013 GC03P037977


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for VILL Gene:
The protein encoded by this gene belongs to the villin/gelsolin family. It contains 6 gelsolin-like repeats and a
headpiece domain. It may play a role in actin-bundling. (provided by RefSeq, Jul 2008)

GeneCards Summary for VILL Gene:
VILL (villin-like) is a protein-coding gene. GO annotations related to this gene include actin binding and structural constituent of cytoskeleton. An important paralog of this gene is SVIL.

UniProtKB/Swiss-Prot: VILL_HUMAN, O15195
Function: Possible tumor suppressor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VILL gene promoter:
         Max1   GR   USF1   GR-beta   Max   Nkx6-1   USF-1   ARP-1   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVILL promoter sequence
   Search Chromatin IP Primers for VILL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VILL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p22.2   HGNC cytogenetic band: 3p21

VILL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VILL gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P038029:  view genomic region     (about GC identifiers)

Start:
38,029,550 bp from pter      End:
38,048,679 bp from pter
Size:
19,130 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: VILL_HUMAN, O15195 (See protein sequence)
Recommended Name: Villin-like protein  
Size: 856 amino acids; 95907 Da
Sequence caution: Sequence=AAH00243.1; Type=Erroneous initiation; Sequence=AAH04300.1; Type=Erroneous initiation;
Secondary accessions: A8MZP1 Q9BT80 Q9BWH7
Alternative splicing: 2 isoforms:  O15195-1   O15195-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VILL: NX_O15195

Explore proteomics data for VILL at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for VILL (O15195)
     KEAVAWG  LPEGVDP 


    See VILL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056957.3  
    ENSEMBL proteins: 
     ENSP00000283713   ENSP00000393661   ENSP00000427355   ENSP00000422096   ENSP00000387659  
     ENSP00000373266  

    VILL Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for VILL
    OriGene Protein Over-expression Lysate for VILL
    OriGene Custom MassSpec
    OriGene Custom Protein Services for VILL
    GenScript Custom Purified and Recombinant Proteins Services for VILL
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for VILL

     
    Search eBioscience for Proteins for VILL 

    VILL Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for VILL
    Novus Biologicals VILL Antibody
    Abcam antibodies for VILL
    Cloud-Clone Corp. Antibodies for VILL
    Search ThermoFisher Antibodies for VILL
    LSBio Antibodies in human, mouse, rat for VILL

    VILL Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for VILL
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for VILL
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for VILL
    Cloud-Clone Corp. CLIAs for VILL
    Search eBioscience for ELISAs for VILL 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    4 InterPro protein domains:
     IPR015626 Villin-like
     IPR007122 Villin/Gelsolin
     IPR003128 Villin_headpiece
     IPR007123 Gelsolin_dom

    Graphical View of Domain Structure for InterPro Entry O15195

    ProtoNet protein and cluster: O15195

    4 Blocks protein domains:
    IPB001199 Cytochrome b5
    IPB003128 Villin headpiece
    IPB007122 Gelsolin family signature
    IPB007123 Gelsolin region


    UniProtKB/Swiss-Prot: VILL_HUMAN, O15195
    Similarity: Belongs to the villin/gelsolin family
    Similarity: Contains 6 gelsolin-like repeats
    Similarity: Contains 1 HP (headpiece) domain


    Find genes that share domains with VILL           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VILL_HUMAN, O15195
    Function: Possible tumor suppressor

         Genatlas biochemistry entry for VILL:
    Villin-like

         Enzyme Numbers (IUBMB): EC 2.2.1.22 EC 6.3.2.62

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005200structural constituent of cytoskeleton TAS9179494
         
    Find genes that share ontologies with VILL           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VILL
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VILL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VILL
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VILL

    miRNA
    Products:
        
    miRTarBase miRNAs that target VILL:
    hsa-mir-335-5p (MIRT018239)

    Block miRNA regulation of human, mouse, rat VILL using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate VILL
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for VILL
    Predesigned siRNA for gene silencing in human, mouse, rat VILL

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for VILL

    Clone
    Products:
         
    OriGene clones in human, mouse for VILL (see all 8)
    OriGene ORF clones in mouse, rat for VILL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: VILL (NM_015873)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VILL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VILL

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for VILL
    Browse ESI BIO Cell Lines and PureStem Progenitors for VILL 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VILL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol3
    nucleus2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015629actin cytoskeleton TAS9179494

    Find genes that share ontologies with VILL           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VILL
    Interactions:

        Search GeneGlobe Interaction Network for VILL

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for VILL (ENSP000002837134) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FSCN1ENSP000003717984STRING: ENSP00000371798
    FSCN2ENSP000003346654STRING: ENSP00000334665
    FSCN3ENSP000002658254STRING: ENSP00000265825
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization IEA--
    GO:0051693actin filament capping IEA--

    Find genes that share ontologies with VILL           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VILL



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for VILL gene: 
    NM_015873.3  

    Unigene Cluster for VILL:

    Villin-like
    Hs.103665  [show with all ESTs]
    Unigene Representative Sequence: BC004300
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283713(uc003chj.3) ENST00000416303 ENST00000492491 ENST00000460040
    ENST00000484717(uc010hgu.3) ENST00000465644 ENST00000412008 ENST00000463080
    ENST00000486616 ENST00000488209 ENST00000383759(uc003chk.1 uc003chl.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat VILL using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate VILL
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for VILL
    Predesigned siRNA for gene silencing in human, mouse, rat VILL
    Clone
    Products:
         
    OriGene clones in human, mouse for VILL (see all 8)
    OriGene ORF clones in mouse, rat for VILL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: VILL (NM_015873)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VILL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VILL
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for VILL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VILL
      QuantiTect SYBR Green Assays in human, mouse, rat VILL
      QuantiFast Probe-based Assays in human, mouse, rat VILL

    Additional mRNA sequence: 

    AK309304.1 BC000243.1 BC004300.1 D88154.1 

    7 DOTS entries:

    DT.308947  DT.102823312  DT.95366465  DT.95310672  DT.91749545  DT.95183565  DT.97839913 

    Selected AceView cDNA sequences (see all 62):

    AA992660 BC000243 BE615005 CF131450 AA641469 AL551271 BU689745 BM714810 
    BC004300 CA433458 CR591344 BE707684 BM837100 BU689742 BM560282 BM673528 
    AL040451 BI825678 BM981806 BQ478235 CD627252 BM906462 AX810712 BE256745 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for VILL (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b
    SP1:                                                        -           -                             -                             -                     
    SP2:                                                                                                                                                      
    SP3:                                                        -                                                                                             
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for VILL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    VILL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCACGTGGA
    VILL Expression
    About this image


    VILL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 3 entries
             Hindgut
     
     Neural Tube (Nervous System)
             Mesencephalic Floor Plate
     
     Lung (Respiratory System)
     
     Stomach (Gastrointestinal Tract)
    VILL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VILL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.103665

    UniProtKB/Swiss-Prot: VILL_HUMAN, O15195
    Tissue specificity: Ubiquitously expressed in 16 tissues examined

        Custom PCR Arrays for VILL
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for VILL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VILL
    QuantiTect SYBR Green Assays in human, mouse, rat VILL
    QuantiFast Probe-based Assays in human, mouse, rat VILL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VILL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for VILL gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vill1 , 5 villin-like1, 5 79.94(n)1
    72.25(a)1
      9 (71.32 cM)5
    223511  NM_001164567.11  NP_001158039.11 
     1190527785 
    chicken
    (Gallus gallus)
    Aves VILL1 villin-like 64.67(n)
    59.16(a)
      420415  XM_004939116.1  XP_004939173.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkeyp-57f11.26
    si:dkeyp-57f11.2
    11(a)
    many ↔ many
    3(39107635-39166750) ENSDARG00000017036
    fruit fly
    (Drosophila melanogaster)
    Insecta qua6
    quail
    25(a)
    1 ↔ 1
    2L(17486806-17497203)
    worm
    (Caenorhabditis elegans)
    Secernentea gsnl-16
    Protein GSNL-1 (gsnl-1) mRNA, complete cds
    32(a)
    1 ↔ 1
    V(9497051-9499378) WBGene00010593


    ENSEMBL Gene Tree for VILL (if available)
    TreeFam Gene Tree for VILL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for VILL gene
    SVIL2  FLII2  AVIL2  SCIN2  GSN2  CAPG2  VIL12  
    7 SIMAP similar genes for VILL using alignment to 5 protein entries:     VILL_HUMAN (see all proteins):
    DKFZp313L0718    VIL1    AVIL    SVIL    GSN    SCIN
    CAPG

    Find genes that share paralogs with VILL           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for VILL (see all 489)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1868235881,2
    --38033090(+) GAGAAA/GGGGAA 1 -- us2k10--------
    rs1896336141,2
    --38033246(+) TCCCCA/TGAGGA 1 -- us2k10--------
    rs1123531921,2
    C,F--38033325(+) GAGGGC/TTTGGG 1 -- us2k12Minor allele frequency- T:0.50NA CSA 4
    rs1834066131,2
    C--38033346(+) TGGCAA/CTGTGG 1 -- us2k10--------
    rs1181011871,2
    F--38033370(+) CCCCAA/GTCTTT 1 -- us2k11Minor allele frequency- G:0.01EA 120
    rs98728041,2
    C,F,A--38033462(+) GAGGGC/TTTGGC 1 -- us2k19Minor allele frequency- T:0.32WA NA CSA EA 368
    rs1386061381,2
    C--38033473(+) TCTACA/GGGCTG 1 -- us2k10--------
    rs1878186391,2
    --38033509(+) GACCCC/TTGGGG 1 -- us2k10--------
    rs1923085511,2
    --38033515(+) TGGGGG/TCGATG 1 -- us2k10--------
    rs730608051,2
    C,F--38033516(+) GGGGGC/TGATGC 1 -- us2k14Minor allele frequency- T:0.08NA CSA WA 242

    HapMap Linkage Disequilibrium report for VILL (38029550 - 38048679 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for VILL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428416CNV Loss18775914
    nsv522354CNV Loss19592680
    dgv1448e1CNV Complex17122850
    dgv1447e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VILL
    DNA2.0 Custom Variant and Variant Library Synthesis for VILL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for VILL gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with VILL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line. (PubMed id 9179494)1, 2, 3 Ishikawa S.... Nakamura Y. (DNA Res. 1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. (PubMed id 18022635)1 Piana S....Martins J.C. (J. Mol. Biol. 2008)
    4. Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state. (PubMed id 18006815)1 Yamamichi N....Iba H. (Cancer Res. 2007)
    5. Interaction of phospholipase C-gamma1 with villin regulates epithelial cell migration. (PubMed id 16921170)1 Tomar A.... Khurana S. (J. Biol. Chem. 2006)
    6. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. The villin-like protein encoded by the Drosophila quail gene is required for actin bundle assembly during oogenesis. (PubMed id 8044841)9 Mahajan-Miklos S. and Cooley L. (Cell 1994)
    9. Villidin, a novel WD-repeat and villin-related protein from Dictyostelium, is associated with membranes and the cytoskeleton. (PubMed id 12857859)9 Gloss A....Noegel A.A. (Mol. Biol. Cell 2003)
    10. Drosophila fascin mutants are rescued by overexpression of the villin-like protein, quail. (PubMed id 9405306)9 Cant K....Cooley L. (J. Cell. Sci. 1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 50853 HGNC: 30906 AceView: VILL Ensembl:ENSG00000136059 euGenes: HUgn50853
    ECgene: VILL H-InvDB: VILL

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for VILL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for VILL gene:
    Search GeneIP for patents involving VILL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for VILL  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for VILL  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for VILL  
     OriGene qSTAR qPCR primer pairs in human, mouse for VILL   OriGene Purified Protein for VILL  
     OriGene ORF clones in mouse, rat for VILL   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for VILL   OriGene Custom Protein Services for VILL  

     
     
     Block miRNA regulation of human, mouse, rat VILL using miScript Target Protectors SeqTarget long-range PCR primers for resequencing VILL
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VILL Predesigned siRNA for gene silencing in human, mouse, rat VILL
     QuantiFast Probe-based Assays in human, mouse, rat VILL QuantiTect SYBR Green Assays in human, mouse, rat VILL
     Custom PCR Arrays for VILL Search Chromatin IP Primers for VILL
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VILL  Search GeneGlobe Interaction Network for VILL
     Regulatory tfbs in VILL promoter
     GenScript Custom Purified and Recombinant Proteins Services for VILL GenScript cDNA clones with any tag delivered in your preferred vector for VILL
     GenScript Custom Assay Services for VILL GenScript Custom overexpressing Cell Line Services for VILL
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for VILL
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     VILL antibodies
     Antibodies for VILL
     See all of Abcam's Antibodies, Kits and Proteins for VILL
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for VILL
     Antibodies for VILL
     ELISAs for VILL
     CLIAs for VILL



     Browse ESI BIO Cell Lines and PureStem Progenitors for VILL
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VILL
     Browse SwitchGear 3'UTR luciferase reporter plasmids for VILL
     SwitchGear Promoter luciferase reporter plasmids for VILL
     Search ThermoFisher Antibodies for VILL
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VILL
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VILL
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VILL
     LSBio Antibodies in human, mouse, rat for VILL
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for VILL
      Search eBioscience for proteins for VILL
      Search eBioscience for elisas for VILL
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      VILL gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4