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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VGF Gene

protein-coding   GIFtS: 49
GCID: GC07M100805

VGF nerve growth factor inducible
 Explore 17 diseases affiliated with
VGF via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for VGF    

Aliases
for VGF gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
VGF Nerve Growth Factor Inducible1 2
Neuro-Endocrine Specific Protein VGF2
Neurosecretory Protein VGF2

External Ids:    HGNC: 126841   Entrez Gene: 74252   Ensembl: ENSG000001285647   OMIM: 6021865   UniProtKB: O152403   

Export aliases for VGF gene to outside databases

Previous GC identifers: GC07M099289 GC07M100352 GC07M100365 GC07M100401 GC07M100592 GC07M095398


Summaries
for VGF gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for VGF:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth
factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the
untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also
shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: VGF_HUMAN, O15240
Function: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the
nervous system (By similarity)
Function: NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release
Function: Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity
against P. Pastoris




Genomic Views
for VGF gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VGF gene promoter:
         CREB   Pax-5   deltaCREB   Pax-6   HTF   Olf-1   STAT3   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): VGF promoter sequence
   Search SABiosciences Chromatin IP Primers for VGF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VGF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

VGF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VGF gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M100805:  view genomic region     (about GC identifiers)

Start:
 100,805,790 bp from pter      End:
 100,808,874 bp from pter
Size:
 3,085 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 100,164,177-100,167,239     

Proteins
for VGF gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: VGF_HUMAN, O15240 (See protein sequence)
Recommended Name: Neurosecretory protein VGF precursor  
Size: 615 amino acids; 67258 Da
Subcellular location: Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory vesicles and then
secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus
Secondary accessions: Q9UDW8

Explore the universe of human proteins at neXtProt for VGF: NX_O15240

Post-translational modifications:

  • Multiple peptides are derived from VGF, with activities in synaptic plasticity, antidepression, penile erection,
    • autonomic activation, and increases in energy expenditure (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15240

    • VGF Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003369.2  
    ENSEMBL proteins: 
     ENSP00000249330   ENSP00000400884  

    Human Recombinant Protein Products: 
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    Novus Biologicals VGF Protein
    Novus Biologicals VGF Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for VGF

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA15706611
    GO:0030133transport vesicle IEA--
    GO:0030667secretory granule membrane ----
    GO:0031410cytoplasmic vesicle IDA17440014
    GO:0043005neuron projection ----


    VGF for ontologies           About GeneDecksing



    VGF Antibody Products: 
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    Uscn Antibodies for VGF
    ThermoFisher Antibodies for VGF

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    Uscn ELISAs and CLIAs for VGF

    Protein Domains /
    Families
    for VGF gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    VGF for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026128 VGF

    Graphical View of Domain Structure for InterPro Entry O15240

    ProtoNet protein and cluster: O15240


    Function
    for VGF gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: VGF_HUMAN, O15240
    Function: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the
    nervous system (By similarity)
    Function: NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release
    Function: Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity
    against P. Pastoris

         Genatlas biochemistry entry for VGF:
    neurotrophin responsive factor,70kDa,expressed in the brain,with a C terminal region encoding posttranslationaly
    processed peptides

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VGF
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate VGF (see all 11):
    hsa-miR-3163 hsa-miR-548p hsa-miR-3184 hsa-miR-1914* hsa-miR-3605-3p hsa-miR-548o hsa-miR-138-2* hsa-miR-423-5p
    SwitchGear 3'UTR luciferase reporter plasmid: VGF 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VGF (see all 7)
    OriGene shRNA RFP: VGF
    OriGene siRNA: VGF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VGF

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VGF (see all 3)
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    Search LifeMap BioReagents cell lines for VGF

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005184neuropeptide hormone activity IEA--
    GO:0008083growth factor activity IEA--


    VGF for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Vgftm1Srjs for VGF
         9 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Vgf):
     adipose tissue  behavior/neurological  endocrine/exocrine gland  growth/size  homeostasis/metabolism 
     integument  mortality/aging  nervous system  reproductive system 

    VGF for phenotypes           About GeneDecksing


    Pathways & Interactions
    for VGF gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VGF

    3 Interacting proteins for VGF (O152403) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GRB2P629933I2D: score=2 
    APLP1P516933I2D: score=1 
    MAPK3P273613I2D: score=1 
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001541ovarian follicle development IEA--
    GO:0002021response to dietary excess IEA--
    GO:0006091generation of precursor metabolites and energy IEA--
    GO:0009409response to cold IEA--
    GO:0019953sexual reproduction IEA--


    VGF for ontologies           About GeneDecksing



    Drugs & Compounds
    for VGF gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    VGF for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VGF
    5 Novoseek chemical compound relationships for VGF gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    forskolin 25.8 3 8395923 (1), 7476021 (1)
    cyclic amp 23.4 1 9084409 (1)
    tyrosine 16.2 4 8525617 (3), 7875312 (1)
    thymidine 14.2 2 12522439 (1), 12603984 (1)
    vegf 0 1 14645477 (1)

    Search CenterWatch for drugs/clinical trials and news about VGF 

    Transcripts
    for VGF gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for VGF gene: 
    NM_003378.3  

    Unigene Cluster for VGF:

    VGF nerve growth factor inducible
    Hs.587325  [show with all ESTs]
    Unigene Representative Sequence: BC063835
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000249330(uc003uxx.4) ENST00000445482

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VGF
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate VGF (see all 11):
    hsa-miR-3163 hsa-miR-548p hsa-miR-3184 hsa-miR-1914* hsa-miR-3605-3p hsa-miR-548o hsa-miR-138-2* hsa-miR-423-5p
    SwitchGear 3'UTR luciferase reporter plasmid: VGF 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VGF (see all 7)
    OriGene shRNA RFP: VGF
    OriGene siRNA: VGF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VGF
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VGF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VGF

    Additional cDNA sequence: 

    AK225839.1 BC006217.2 BC036537.1 BC044212.1 BC063835.1 

    5 DOTS entries:

    DT.91892495  DT.97794502  DT.101984471  DT.300806  DT.75102021 

    24/86 AceView cDNA sequences (see all 86):

    BC006217 CK904657 AI636497 NM_003378 BM052867 BQ639541 BM068821 BQ637569 
    BE855486 BM263198 AW245132 BM142488 BM142297 CK820236 BU784525 BI963104 
    BM726762 BM126861 CD108874 CK904961 BC044212 BC063835 BG236881 BU166517 

    GeneLoc Exon Structure


    Expression
    for VGF gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VGF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGCCCCGGCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    VGF expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Ventral/hypothalamic-like neurons (Generation of midbra...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See VGF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VGF

    SOURCE GeneReport for Unigene cluster: Hs.587325

    UniProtKB/Swiss-Prot: VGF_HUMAN, O15240
    Tissue specificity: Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine
    cells

        SABiosciences Expression via Pathway-Focused PCR Array including VGF: 
              Neurotrophins & Receptors in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for VGF gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for VGF gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Vgf1 , 5 VGF nerve growth factor inducible1, 5 85.48(n)1
    86.3(a)1    		   5 (76.13 cM)5
    3816771  NM_001039385.11  NP_001034474.11 
     1370302955 
    zebrafish
    (Danio rerio)    		 Actinopterygii si:dkey-175g6.21 si:dkey-175g6.2 46.77(n)
    34.88(a)    		   793455  XM_001333183.1  XP_001333219.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.467622 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.39(n)    AK120364.1 


    ENSEMBL Gene Tree for VGF (if available)
    TreeFam Gene Tree for VGF (if available) 

    Paralogs
    for VGF gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for VGF gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/62 NCBI SNPs in VGF are shown (see all 62)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1162829121,2
    		F,--100805369(+) GTGAAC/TACAGG 1 -- ds50011Minor allele frequency- T:0.07WA 118
    rs1447682691,2
    		--100805451(+) ACCTTA/CTGCGG 1 -- ds50010--------
    rs107558661,2
    		C,F,A,H,--100805460(+) GGGTCA/GCCTTT 1 -- ds500128Minor allele frequency- G:0.40NS EA NA WA CSA 2777
    rs109533251,2
    		C,F,A,H,--100805508(+) AATTGG/ACTCTT 1 -- ds500129Minor allele frequency- A:0.44NS EA NA WA CSA 2957
    rs1876842011,2
    		--100805520(+) TATTGC/GATTCC 1 -- ds50010--------
    rs1457034721,2
    		--100805598(+) AATTTC/TGGGTT 1 -- ds50010--------
    rs21078041,2
    		C,H,--100805671(+) CCCCTC/TGCCTT 1 -- ds500111Minor allele frequency- T:0.01NA WA CSA EA 372
    rs1140632001,2
    		C,--100805678(+) CCTTAA/GTTTGG 1 -- ds50010--------
    rs99186351,2
    		C,F,A,H,--100805704(+) GGAGAT/CGGGGA 1 -- ds500127Minor allele frequency- C:0.40NS EA NA WA CSA 2755
    rs1846555711,2
    		--100805921(+) GGCCCA/GAAGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for VGF (100805790 - 100808874 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for VGF
         2 CNVs: 8576 5245

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    DNA2.0 Custom Variant and Variant Library Synthesis for VGF

    Disorders / Diseases
    for VGF gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    VGF for disorders           About GeneDecksing

    OMIM gene information: 602186    OMIM disorders: --

    17 diseases for VGF:    About MalaCards
    amyotrophic lateral sclerosis (als)    amyotrophic lateral sclerosis    pulmonary large cell neuroendocrine carcinoma    lateral sclerosis
    neuroendocrine carcinoma    pheochromocytoma    vaccinia    alzheimer's disease
    seizures    lung cancer    breast cancer    carcinoma
    neuroblastoma    schizophrenia    thyroiditis    pancreatitis
    neuronitis

    2 Novoseek disease relationships for VGF gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pheochromocytoma 38.8 3 9478934 (1), 1469059 (1), 9084409 (1)
    tumors 0 2 18328103 (1)

    Human Genome Epidemiology (HuGE) Navigator: VGF (3 documents)

    Export disorders for VGF gene to outside databases

    Publications
    for VGF gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VGF gene, integrated from 9 sources (see all 72):
    (articles sorted by number of sources associating them with VGF)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, structural organization analysis and chromosomal assignment of the human gene for neurosecretory protein VGF. (PubMed id 9344675)1, 2, 3, 9 Canu N.... Levi A. (1997)
    2. The expression of VGF is reduced in leukocytes of dep ressed patients and it is restored by effective antidepressant treatment. (PubMed id 20164831)1, 9 Cattaneo A....Gennarelli M. (2010)
    3. Molecular cloning and characterization of the human VGF promoter region. (PubMed id 9084409)1, 9 Canu N....Levi A. (1997)
    4. Neuroendocrine regulatory peptide-1 and -2: novel bio active peptides processed from VGF. (PubMed id 19194657)2, 9 Toshinai K. and Nakazato M. (2009)
    5. Staurosporine enhances cAMP-induced expression of neural-specific gene VGF and tyrosine hydroxylase. (PubMed id 10381005)1, 9 Nagasaki K....Yamaguchi K. (1999)
    6. Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families. (PubMed id 17684500)1, 9 Wedenoja J....Peltonen L. (2008)
    7. Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry. (PubMed id 23250050)2 Sasaki K.... Minamino N. (2012)
    8. VGF: an inducible gene product, precursor of a diverse array of neuro-endocrine peptides and tissue-specific disease biomarkers. (PubMed id 21621608)1 Ferri G.L....Cocco C. (2011)
    9. An inducer of VGF protects cells against ER stress-in duced cell death and prolongs survival in the mutant SOD1 animal models of fami lial ALS. (PubMed id 21151573)1 Shimazawa M....Hara H. (2010)
    10. Localization of neuroendocrine regulatory peptide-1 a nd-2 in human tissues. (PubMed id 20471433)1 Matsuo T....Nakazato M. (2010)

    External Searches for VGF gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing VGF gene

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    Entrez Gene: 7425 HGNC: 12684 AceView: VGF Ensembl:ENSG00000128564 euGenes: HUgn7425
    ECgene: VGF H-InvDB: VGF

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    Specialized Databases showing VGF gene

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