Aliases for VGF Gene
External Ids for VGF Gene
Previous GeneCards Identifiers for VGF Gene
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
GeneCards Summary for VGF Gene
VGF (VGF Nerve Growth Factor Inducible) is a Protein Coding gene. Diseases associated with VGF include Pulmonary Large Cell Neuroendocrine Carcinoma and Pheochromocytoma. Gene Ontology (GO) annotations related to this gene include growth factor activity and neuropeptide hormone activity.
UniProtKB/Swiss-Prot for VGF Gene
May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.
NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release.
Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris.