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VGF Gene

protein-coding   GIFtS: 52
GCID: GC07M100805

VGF Nerve Growth Factor Inducible

  See VGF-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
VGF Nerve Growth Factor Inducible1 2
Neuro-Endocrine Specific Protein VGF1 2
Neurosecretory Protein VGF2

External Ids:    HGNC: 126841   Entrez Gene: 74252   Ensembl: ENSG000001285647   OMIM: 6021865   UniProtKB: O152403   

Export aliases for VGF gene to outside databases

Previous GC identifers: GC07M099289 GC07M100352 GC07M100365 GC07M100401 GC07M100592 GC07M095398


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VGF Gene:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth
factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and
the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein
also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.
(provided by RefSeq, Jul 2008)

GeneCards Summary for VGF Gene:
VGF (VGF nerve growth factor inducible) is a protein-coding gene. Diseases associated with VGF include pulmonary large cell neuroendocrine carcinoma, and vaccinia. GO annotations related to this gene include neuropeptide hormone activity and growth factor activity.

UniProtKB/Swiss-Prot: VGF_HUMAN, O15240
Function: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of
the nervous system (By similarity)
Function: NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release
Function: Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity
against P. Pastoris




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VGF gene promoter:
         CREB   Pax-5   deltaCREB   Pax-6   HTF   Olf-1   STAT3   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): VGF promoter sequence
   Search Chromatin IP Primers for VGF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VGF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

VGF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VGF gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M100805:  view genomic region     (about GC identifiers)

Start:
100,805,790 bp from pter      End:
100,808,874 bp from pter
Size:
3,085 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 100,164,177-100,167,239     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: VGF_HUMAN, O15240 (See protein sequence)
Recommended Name: Neurosecretory protein VGF precursor  
Size: 615 amino acids; 67258 Da
Secondary accessions: Q9UDW8

Explore the universe of human proteins at neXtProt for VGF: NX_O15240

Explore proteomics data for VGF at MOPED

Post-translational modifications: 

  • Multiple peptides are derived from VGF, with activities in synaptic plasticity, antidepression, penile erection,
    autonomic activation, and increases in energy expenditure (By similarity)1
  • Glycosylation2 at Thr180, Thr187, Thr189, Thr191, Thr193, Ser252, Ser253, Thr256, Ser266, Thr554
  • Modification sites at PhosphoSitePlus

  • See VGF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003369.2  
    ENSEMBL proteins: 
     ENSP00000249330   ENSP00000400884  

    VGF Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for VGF 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026128 VGF

    Graphical View of Domain Structure for InterPro Entry O15240

    ProtoNet protein and cluster: O15240


    Find genes that share domains with VGF           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VGF_HUMAN, O15240
    Function: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of
    the nervous system (By similarity)
    Function: NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release
    Function: Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity
    against P. Pastoris

         Genatlas biochemistry entry for VGF:
    neurotrophin responsive factor,70kDa,expressed in the brain,with a C terminal region encoding posttranslationaly
    processed peptides

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005184neuropeptide hormone activity IEA--
    GO:0008083growth factor activity IEA--
         
    Find genes that share ontologies with VGF           About GenesLikeMe


    Phenotypes:
         9 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Vgf):
     adipose tissue  behavior/neurological  endocrine/exocrine gland  growth/size/body  homeostasis/metabolism 
     integument  mortality/aging  nervous system  reproductive system 

    Find genes that share phenotypes with VGF           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Vgftm1Srjs for VGF

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VGF
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VGF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VGF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VGF

    miRNA
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    Block miRNA regulation of human, mouse, rat VGF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VGF (see all 11):
    hsa-miR-3163 hsa-miR-548p hsa-miR-3184 hsa-miR-1914* hsa-miR-3605-3p hsa-miR-548o hsa-miR-138-2* hsa-miR-423-5p
    SwitchGear 3'UTR luciferase reporter plasmidVGF 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VGF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VGF_HUMAN, O15240: Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory vesicles and then
    secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    nucleus2
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA15706611
    GO:0030133transport vesicle IEA--
    GO:0031410cytoplasmic vesicle IDA17440014

    Find genes that share ontologies with VGF           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including VGF: 
              Neurotrophins & Receptors in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for VGF

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for VGF (O152403 ENSP000002493304) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK3P273613, ENSP000002630254I2D: score=1 STRING: ENSP00000263025
    GRB2P629933I2D: score=2 
    APLP1P516933I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001541ovarian follicle development IEA--
    GO:0002021response to dietary excess IEA--
    GO:0006091generation of precursor metabolites and energy IEA--
    GO:0009409response to cold IEA--
    GO:0019953sexual reproduction IEA--

    Find genes that share ontologies with VGF           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VGF

    5 Novoseek inferred chemical compound relationships for VGF gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    forskolin 25.8 3 8395923 (1), 7476021 (1)
    cyclic amp 23.4 1 9084409 (1)
    tyrosine 16.2 4 8525617 (3), 7875312 (1)
    thymidine 14.2 2 12522439 (1), 12603984 (1)
    vegf 0 1 14645477 (1)



    Find genes that share compounds with VGF           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for VGF gene: 
    NM_003378.3  

    Unigene Cluster for VGF:

    VGF nerve growth factor inducible
    Hs.587325  [show with all ESTs]
    Unigene Representative Sequence: BC063835
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000249330(uc003uxx.4) ENST00000445482
    miRNA
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    hsa-miR-3163 hsa-miR-548p hsa-miR-3184 hsa-miR-1914* hsa-miR-3605-3p hsa-miR-548o hsa-miR-138-2* hsa-miR-423-5p
    SwitchGear 3'UTR luciferase reporter plasmidVGF 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VGF
      QuantiTect SYBR Green Assays in human, mouse, rat VGF
      QuantiFast Probe-based Assays in human, mouse, rat VGF

    Additional mRNA sequence: 

    AK225839.1 BC006217.2 BC036537.1 BC044212.1 BC063835.1 

    5 DOTS entries:

    DT.91892495  DT.97794502  DT.101984471  DT.300806  DT.75102021 

    Selected AceView cDNA sequences (see all 86):

    BC044212 BM126861 BC006217 AW207250 CK820236 BI963104 BM263198 BU166517 
    AI636497 BM911486 BM718178 BM068821 BG236881 BE855486 AW245132 CD108874 
    CK904961 BM726762 BM142297 NM_003378 BU784525 BQ639541 BM052867 CK904657 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VGF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCCCCGGCC
    VGF Expression
    About this image


    VGF expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Neurons
             Ventral/hypothalamic-like neurons
     
     Brain (Nervous System)
             Ventral/hypothalamic-like neurons
     
     Pancreas (Endocrine System)
    VGF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VGF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.587325

    UniProtKB/Swiss-Prot: VGF_HUMAN, O15240
    Tissue specificity: Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine
    cells

        Pathway & Disease-focused RT2 Profiler PCR Array including VGF: 
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for VGF gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vgf1 , 5 VGF nerve growth factor inducible1, 5 84.67(n)1
    84.99(a)1
      5 (76.13 cM)5
    3816771  NM_001039385.11  NP_001034474.11 
     1370302955 
    rice
    (Oryza sativa)
    Liliopsida Os.467622 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.39(n)    AK120364.1 


    ENSEMBL Gene Tree for VGF (if available)
    TreeFam Gene Tree for VGF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VGF (see all 89)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1162829121,2
    C,F--100805369(+) GTGAAC/TACAGG 1 -- ds50011Minor allele frequency- T:0.07WA 118
    rs1447682691,2
    --100805451(+) ACCTTA/CTGCGG 1 -- ds50010--------
    rs107558661,2
    C,F,A,H--100805460(+) GGGTCA/GCCTTT 1 -- ds500128Minor allele frequency- G:0.40NS EA NA WA CSA 2777
    rs109533251,2
    C,F,A,H--100805508(+) AATTGG/ACTCTT 1 -- ds500129Minor allele frequency- A:0.44NS EA NA WA CSA 2957
    rs1876842011,2
    --100805520(+) TATTGC/GATTCC 1 -- ds50010--------
    rs1457034721,2
    C--100805598(+) AATTTC/TGGGTT 1 -- ds50010--------
    rs21078041,2
    C,H--100805671(+) CCCCTC/TGCCTT 1 -- ds500111Minor allele frequency- T:0.01NA WA CSA EA 372
    rs1140632001,2
    C,F--100805678(+) CCTTAA/GTTTGG 1 -- ds50010--------
    rs99186351,2
    C,F,A,H--100805704(+) GGAGAT/CGGGGA 1 -- ds500127Minor allele frequency- C:0.40NS EA NA WA CSA 2755
    rs1846555711,2
    --100805921(+) GGCCCA/GAAGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for VGF (100805790 - 100808874 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for VGF:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    esv2422376CNV Duplication17116639
    dgv7409n71CNV Loss21882294
    nsv831075CNV Loss17160897
    esv2752134CNV Gain17911159
    nsv824241CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VGF
    DNA2.0 Custom Variant and Variant Library Synthesis for VGF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602186    OMIM disorders: --

    3 diseases for VGF:    
    About MalaCards
    pulmonary large cell neuroendocrine carcinoma    vaccinia    pheochromocytoma


    Find genes that share disorders with VGF           About GenesLikeMe

    2 Novoseek inferred disease relationships for VGF gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pheochromocytoma 38.8 3 9478934 (1), 1469059 (1), 9084409 (1)
    tumors 0 2 18328103 (1)

    Genetic Association Database (GAD): VGF
    Human Genome Epidemiology (HuGE) Navigator: VGF (3 documents)

    Export disorders for VGF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VGF gene, integrated from 10 sources (see all 76):
    (articles sorted by number of sources associating them with VGF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, structural organization analysis and chromosomal assignment of the human gene for neurosecretory protein VGF. (PubMed id 9344675)1, 2, 3, 9 Canu N.... Levi A. (Genomics 1997)
    2. Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. (PubMed id 19598235)1, 4 Chakrabarti B....Baron-Cohen S. (Autism Res 2009)
    3. The expression of VGF is reduced in leukocytes of depressed patients and it is restored by effective antidepressant treatment. (PubMed id 20164831)1, 9 Cattaneo A....Gennarelli M. (Neuropsychopharmacology 2010)
    4. Molecular cloning and characterization of the human VGF promoter region. (PubMed id 9084409)1, 9 Canu N....Levi A. (J. Neurochem. 1997)
    5. Neuroendocrine regulatory peptide-1 and -2: novel bioactive peptides processed from VGF. (PubMed id 19194657)2, 9 Toshinai K. and Nakazato M. (Cell. Mol. Life Sci. 2009)
    6. Staurosporine enhances cAMP-induced expression of neural-specific gene VGF and tyrosine hydroxylase. (PubMed id 10381005)1, 9 Nagasaki K....Yamaguchi K. (Neurosci. Lett. 1999)
    7. Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families. (PubMed id 17684500)1, 9 Wedenoja J....Peltonen L. (Mol. Psychiatry 2008)
    8. Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry. (PubMed id 23250050)2 Sasaki K.... Minamino N. (Mol. Cell. Proteomics 2013)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7425 HGNC: 12684 AceView: VGF Ensembl:ENSG00000128564 euGenes: HUgn7425
    ECgene: VGF H-InvDB: VGF

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VGF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for VGF gene:
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