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Aliases & Descriptions for VEZF1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| DB1 1, 2, 3 | | ZNF161 2, 3, 5 |
| | | Descriptions |
|---|
| Putative transcription factor DB1 3 | | Zinc finger protein 161 1, 2, 3 | | vascular endothelial zinc finger 1 2 |
|
| | Search outside databases for aliases for VEZF1 gene |
Summaries for VEZF1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for VEZF1: Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.[supplied by OMIM] UniProtKB/Swiss-Prot: VEZF1_HUMAN, Q14119Function: Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3 |
Genomic Location for VEZF1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q22 Ensembl cytogenetic band: 17q22 HGNC cytogenetic band: 17q22VEZF1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M053403:
(about GC identifiers)
Start:
|
53,403,909 bp from pter |
End:
|
53,420,614 bp from pter |
Size:
|
16,706 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000017.9 NT_010783.14
| Proteins for VEZF1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: VEZF1_HUMAN, Q14119 (See
protein sequence)Recommended Name: Vascular endothelial zinc finger 1 Size: 516 amino acids; 56363 Da
Subunit: Interacts with ARHGAP22 (By similarity)
Subcellular location: NucleusPost-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_009077.2
ENSEMBL proteins: ENSP00000258963
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for VEZF1: Assays for VEZF1: | Protein
Domains/ Families for VEZF1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q14119
ProtoNet protein and cluster: Q14119 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: VEZF1_HUMAN, Q14119Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 6 C2H2-type zinc fingers | Gene Function for VEZF1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007146
Applied Biosystems Silencer® siRNAs for VEZF1
Sigma-Aldrich siRNA for VEZF1  Sigma-Aldrich shRNA for VEZF1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_007146                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_007146                                  untagged cDNA clone in CMV expression vector: NM_007146 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_007146
UniProtKB/Swiss-Prot: VEZF1_HUMAN, Q14119Function: Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-35 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Vezf1):
4 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for VEZF1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
3 Interacting proteins for VEZF1 (ENSP000002589633) via UniProtKB, MINT, and/or STRINGAbout this table
5 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for VEZF1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for VEZF1
|
Transcripts for VEZF1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_007146
Sigma-Aldrich siRNA for VEZF1  Sigma-Aldrich shRNA for VEZF1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_007146 REFSEQ mRNAs for VEZF1 gene: NM_007146.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_007146               OriGene GFP tagged cDNA clone in CMV expression vector: NM_007146                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_007146                                  untagged cDNA clone in CMV expression vector: NM_007146  Additional cDNA sequence: AK058024.1 BX648862.1 CR609476.1 D28118.1 10 DOTS entries: DT.100793587 DT.92431525 DT.95188994 DT.100793579 DT.120850471 DT.40294655 DT.75188496 DT.92431527 DT.100793576 DT.120937961 24/298 AceView cDNA sequences (see all 298
):AW183892 AA227945 BE669734 AI263125 AA026448 BX109922 BE672621 BM977996 AI208612 BU729102 BM669599 BI966844 BM873386 H87224 CK903633 AW079327 CR609476 BM676135 AI383027 AI689597 AA746113 CA941584 T92348 AI202735
highest scoring ESTs for VEZF1:AI128606 D28118 AA033866 AA034054 AA045464 AA115815 AA195025 AA195154 AA232647 AA336595 Unigene Cluster for VEZF1: Vascular endothelial zinc finger 1 Hs.463569 [show with all ESTs]Unigene Representative Sequence: NM_007146
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000258963
|
Expression for VEZF1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| VEZF1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for VEZF1
1 / 2 / 3 10 probe-sets matching VEZF1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.463569 UniProtKB/Swiss-Prot: VEZF1_HUMAN, Q14119Tissue specificity: Ubiquitously expressed. Highest levels in skeletal muscle and kidney |
Orthologs for VEZF1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for VEZF1 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for VEZF1
ENSEMBL Gene Tree for VEZF1 | Paralogs for VEZF1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for VEZF1 gene
- MAZ2 ENSG000002128502 PATZ12
Pseudogenes
- 1 related pseudogene
|
SNPs/Variants for VEZF1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for VEZF1 (up to first 250kb)
|
Disorders & Mutations for VEZF1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 606747
|
Medical News for VEZF1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for VEZF1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 5 PubMed articles for VEZF1 gene: |
Search for VEZF1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing VEZF1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing VEZF1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VEZF1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for VEZF1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for VEZF1:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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