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VEPH1 Gene

protein-coding   GIFtS: 49
GCID: GC03M156977

Ventricular Zone Expressed PH Domain-Containing 1

(Previous name: ventricular zone expressed PH domain homolog 1 (zebrafish))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ventricular Zone Expressed PH Domain-Containing 11 2     KIAA16923 5
Protein Melted2 3     Ventricular Zone Expressed PH Domain Homolog 1 (Zebrafish)1
VEPH2 3     Ventricular Zone Expressed PH Domain Homolog 12
MELT2 5     Ventricular Zone-Expressed PH Domain-Containing Protein Homolog 12

External Ids:    HGNC: 257351   Entrez Gene: 796742   Ensembl: ENSG000001974157   OMIM: 6095945   UniProtKB: Q14D043   

Export aliases for VEPH1 gene to outside databases

Previous GC identifers: GC03M158461 GC03M154373


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for VEPH1 Gene:
VEPH1 (ventricular zone expressed PH domain-containing 1) is a protein-coding gene. Diseases associated with VEPH1 include diabetic retinopathy, and atherosclerosis. GO annotations related to this gene include phospholipid binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VEPH1 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   LHX3b/Lhx3b   oct-B3   oct-B2   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): VEPH1 promoter sequence
   Search Chromatin IP Primers for VEPH1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VEPH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q24-q25   Ensembl cytogenetic band:  3q25.32   HGNC cytogenetic band: 3q24-q25

VEPH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VEPH1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M156977:  view genomic region     (about GC identifiers)

Start:
156,977,531 bp from pter      End:
157,251,408 bp from pter
Size:
273,878 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MELT_HUMAN, Q14D04 (See protein sequence)
Recommended Name: Ventricular zone-expressed PH domain-containing protein homolog 1  
Size: 833 amino acids; 94745 Da
Sequence caution: Sequence=BAB14165.1; Type=Erroneous initiation; Sequence=BAB21783.1; Type=Erroneous initiation;
Secondary accessions: D3DNL0 F5GZ91 Q2TAA9 Q3MIX2 Q6PEL3 Q86TL5 Q8TCR3 Q96SP7 Q9C0H1 Q9H9Q7
Alternative splicing: 4 isoforms:  Q14D04-1   Q14D04-2   Q14D04-3   Q14D04-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VEPH1: NX_Q14D04

Explore proteomics data for VEPH1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See VEPH1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001161383.1  NP_001161384.1  NP_001161387.1  NP_001161388.1  NP_001161389.1  NP_078897.2  

    ENSEMBL proteins: 
     ENSP00000376578   ENSP00000354919   ENSP00000376577   ENSP00000418963   ENSP00000419193  
     ENSP00000417268   ENSP00000420097   ENSP00000418175   ENSP00000417700   ENSP00000417157  
     ENSP00000417298   ENSP00000446258   ENSP00000443868  

    VEPH1 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for VEPH1

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    Cloud-Clone Corp. ELISAs for VEPH1
    Cloud-Clone Corp. CLIAs for VEPH1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing

    3 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q14D04

    ProtoNet protein and cluster: Q14D04

    UniProtKB/Swiss-Prot: MELT_HUMAN, Q14D04
    Domain: The PH domain is required for membrane targeting (By similarity)
    Similarity: Belongs to the MELT/VEPH family
    Similarity: Contains 1 PH domain


    VEPH1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
         
    VEPH1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for VEPH1:
     Decreased Wnt reporter activit 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Veph1):
     normal 

    VEPH1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Veph1tm1Wtnb for VEPH1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VEPH1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VEPH1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VEPH1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VEPH1

    miRNA
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    Block miRNA regulation of human, mouse, rat VEPH1 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate VEPH1:
    hsa-miR-3200-5p hsa-miR-607 hsa-miR-767-3p hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidVEPH1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for VEPH1
    Predesigned siRNA for gene silencing in human, mouse, rat VEPH1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 6): VEPH1 (NM_024621)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VEPH1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VEPH1

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    Browse ESI BIO Cell Lines and PureStem Progenitors for VEPH1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VEPH1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MELT_HUMAN, Q14D04: Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    nucleus2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--

    VEPH1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VEPH1
    Interactions:

        Search GeneGlobe Interaction Network for VEPH1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for VEPH1 (Q14D043 ENSP000003549194) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    TGFBR1P368973, ENSP000003641334I2D: score=2 STRING: ENSP00000364133
    SMAD1Q157973, ENSP000003057694I2D: score=2 STRING: ENSP00000305769
    BMPR1BO002383, ENSP000002645684I2D: score=2 STRING: ENSP00000264568
    TSC22D1Q157143, ENSP000003974354I2D: score=1 STRING: ENSP00000397435
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VEPH1 (MELT)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for VEPH1 gene (6 alternative transcripts): 
    NM_001167911.1  NM_001167912.1  NM_001167915.1  NM_001167916.1  NM_001167917.1  NM_024621.2  

    Unigene Cluster for VEPH1:

    Ventricular zone expressed PH domain-containing 1
    Hs.658046  [show with all ESTs]
    Unigene Representative Sequence: NM_024621
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000392833 ENST00000362010(uc003fbk.2 uc010hvu.2) ENST00000392832
    ENST00000472419 ENST00000488772 ENST00000482685 ENST00000469007 ENST00000479987
    ENST00000494677(uc003fbn.3) ENST00000490235 ENST00000468233(uc003fbm.3)
    ENST00000482434 ENST00000487753 ENST00000473907 ENST00000475050 ENST00000461299
    ENST00000489602 ENST00000483440
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat VEPH1 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate VEPH1:
    hsa-miR-3200-5p hsa-miR-607 hsa-miR-767-3p hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidVEPH1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for VEPH1
    Predesigned siRNA for gene silencing in human, mouse, rat VEPH1
    Clone
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    OriGene clones in human, mouse for VEPH1 (see all 32)
    OriGene ORF clones in mouse, rat for VEPH1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): VEPH1 (NM_024621)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VEPH1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VEPH1
    Primer
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    OriGene qPCR primer pairs and template standards for VEPH1
    OriGene qSTAR qPCR primer pairs in human, mouse for VEPH1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VEPH1
      QuantiTect SYBR Green Assays in human, mouse, rat VEPH1
      QuantiFast Probe-based Assays in human, mouse, rat VEPH1

    Additional mRNA sequence: 

    AB051479.1 AK022666.1 AK027625.1 AL713656.1 BC026235.1 BC042159.1 BC057999.1 BC078142.1 
    BC101660.1 BC111017.1 BC113555.1 

    14 DOTS entries:

    DT.100019893  DT.91743516  DT.210958  DT.86840814  DT.120868141  DT.92037020  DT.100686399  DT.120868181 
    DT.40119289  DT.91743511  DT.91743515  DT.91743517  DT.97788622  DT.100777112 

    Selected AceView cDNA sequences (see all 115):

    AK027625 AB051479 NM_024621 AW779807 AI283485 AA917969 AA913641 W81274 
    CA431070 BQ015118 AW236094 AA359252 BE048751 AI277666 AI740705 AW955316 
    BU631955 BC078142 BX419174 W81237 AI168722 BC042159 BC057999 BM083616 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for VEPH1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:                    -     -           -     -                             -                                                               
    SP2:                                      -     -                             -                                                               
    SP3:              -                       -     -                                                                                             
    SP4:              -     -     -           -     -                                                                                             
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for VEPH1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VEPH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATCTTGGA
    VEPH1 Expression
    About this image

    VEPH1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VEPH1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.658046
        Custom PCR Arrays for VEPH1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VEPH1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for VEPH1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Veph11 , 5 ventricular zone expressed PH domain homolog 1 (zebrafish)5
    ventricular zone expressed PH domain-containing 11
    85.15(n)1
    85.47(a)1
      3 (30.25 cM)5
    727891  NM_145820.31  NP_665819.21 
     660535585 
    chicken
    (Gallus gallus)
    Aves VEPH11 ventricular zone expressed PH domain homolog 1 (zebrafish) 73.56(n)
    74.4(a)
      100859365  XM_003641782.2  XP_003641830.1 
    lizard
    (Anolis carolinensis)
    Reptilia VEPH16
    ventricular zone expressed PH domain-containing 1
    70(a)
    1 ↔ 1
    3(14827969-14986402)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia veph11 ventricular zone expressed PH domain-containing 1 66.99(n)
    64.56(a)
      100496304  XM_002933254.2  XP_002933300.2 
    zebrafish
    (Danio rerio)
    Actinopterygii veph1 ventricular zone expressed PH domain protein 62.63(n)
    62.42(a)
      405756  NM_212831.1  NP_997996.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta melt1 melted 48.29(n)
    41.28(a)
      38785  NM_079229.4  NP_523953.2 
    worm
    (Caenorhabditis elegans)
    Secernentea K10B4.31 K10B4.3 45.33(n)
    34.63(a)
      173397  NM_061263.2  NP_493664.2 


    ENSEMBL Gene Tree for VEPH1 (if available)
    TreeFam Gene Tree for VEPH1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VEPH1 (see all 4517)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1836658011,2
    --156977071(+) CATTGC/TTTCTC 3 -- ds50010--------
    rs1162694281,2
    F--156977178(+) TTATTC/TTCTCT 3 -- ds50011Minor allele frequency- T:0.06WA 118
    rs130845221,2
    C,F,H--156977207(+) TTGCAT/CCTTTG 3 -- ds500123Minor allele frequency- C:0.43NA EA NS WA 2706
    rs738736171,2
    C,F--156977642(+) CAAGGC/TGTTGG 3 -- ut311Minor allele frequency- T:0.50WA 2
    rs1440020191,2
    --156977902(+) TTCACA/TTTTGT 3 -- ut310--------
    rs1461390401,2
    --156978000(+) ACTCAA/GTGGGG 3 -- ut310--------
    rs10469381,2
    C,F,A,H--156978173(+) TTTAAC/TGGAGA 3 -- ut3122Minor allele frequency- T:0.49MN NS EA NA WA CSA 2528
    rs1895386101,2
    --156978185(+) GGCACA/GTTATT 3 -- ut310--------
    rs1820043421,2
    --156978257(+) GATATA/GTGTCC 3 -- ut310--------
    rs1401863981,2
    C--156978330(+) GAAAGA/GCAAGT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for VEPH1 (156977531 - 157227531 bp, first 250kb of VEPH1)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for VEPH1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2582112CNV Deletion19546169
    esv274040CNV Insertion20981092
    nsv236425CNV Insertion16902084
    esv270978CNV Insertion20981092
    nsv877687CNV Loss21882294
    esv32988CNV Loss17666407
    nsv829766CNV Gain17160897
    esv275099CNV Gain+Loss21479260
    dgv1525e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VEPH1
    DNA2.0 Custom Variant and Variant Library Synthesis for VEPH1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609594    OMIM disorders: --

    5 diseases for VEPH1:    About MalaCards
    diabetic retinopathy    atherosclerosis    hepatitis b    hepatitis
    malaria


    VEPH1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): VEPH1
    Human Genome Epidemiology (HuGE) Navigator: VEPH1 (5 documents)

    Export disorders for VEPH1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VEPH1 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with VEPH1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates. (PubMed id 15388229)1, 2, 3 Muto E.... Watanabe S. (Biochimie 2004)
    2. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Genome-wide meta-analysis for severe diabetic retinopathy. (PubMed id 21441570)1 Grassi M.A....Nicolae D.L. (Hum. Mol. Genet. 2011)
    7. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    8. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    9. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    10. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PubMed id 17903303)4 O'Donnell C.J....Demissie S. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79674 HGNC: 25735 AceView: FLJ12604 Ensembl:ENSG00000197415 euGenes: HUgn79674
    ECgene: VEPH1 H-InvDB: VEPH1

    (According to HUGE)
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    HUGE: KIAA1692

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VEPH1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VEPH1 gene:
    Search GeneIP for patents involving VEPH1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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