Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

VENTX Gene

protein-coding GIFtS: 48
GCID: GC10P135051

VENT homeobox

(Previous names: VENT-like homeobox 2, VENT homeobox homolog (Xenopus laevis)...)
(Previous symbol: VENTX2)

Explore 4 diseases affiliated with
VENTX via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
VENT Homeobox¹ ²		VENT-Like Homeobox Protein 2² ³
HPX42B¹ ² ³ ⁵		VENT Homeobox Homolog (Xenopus Laevis)¹
VENTX2¹ ² ³ ⁵		NA88A²
VENT-Like Homeobox 2¹ ²		Hemopoietic Progenitor Homeobox Protein VENTX2²
VENT Homeobox Homolog² ³		Homeobox Protein VENTX²

External Ids:	HGNC: 13639¹	Entrez Gene: 27287²	Ensembl: ENSG00000151650⁷	OMIM: 607158⁵	UniProtKB: O95231³

Export aliases for VENTX gene to outside databases

Previous GC identifers: GC10P134941 GC10P128597

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VENTX:

This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a

transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple

pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in

certain melanomas. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: VENTX_HUMAN, O95231

Function: May be involved in ventralization

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_008818.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the VENTX gene promoter:
AhR Nkx3-1 v4 POU2F1 POU2F1a HOXA5 Arnt
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VENTX promoter sequence

Search SABiosciences Chromatin IP Primers for VENTX

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VENTX

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.3 Ensembl cytogenetic band: 10q26.3 HGNC cytogenetic band: 10q26.3

VENTX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VENTX gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P135051: view genomic region (about GC identifiers)

Start:	135,051,175 bp from pter	End:	135,055,433 bp from pter
Size:	4,259 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VENTX_HUMAN, O95231 (See protein sequence)

Recommended Name: Homeobox protein VENTX

Size: 258 amino acids; 27552 Da

Subcellular location: Nucleus (Probable)

Secondary accessions: Q32MZ3

Explore the universe of human proteins at neXtProt for VENTX: NX_O95231

VENTX Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055283.1

ENSEMBL proteins:

ENSP00000357556

Human Recombinant Protein Products for VENTX:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: VENTX OriGene Protein Over-expression Lysate: VENTX OriGene Custom Protein Services for VENTX
	GenScript Custom Purified and Recombinant Proteins Services for VENTX
	Novus Biologicals VENTX Proteins Novus Biologicals VENTX Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for VENTX

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

VENTX for ontologies About GeneDecksing

VENTX Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for VENTX
	GenScript Custom Superior Antibodies Services for VENTX
	Novus Biologicals VENTX Antibodies
	Abcam antibodies for VENTX
	Uscn Antibodies for VENTX
	ThermoFisher Antibodies for VENTX

Assay Products for VENTX:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for VENTX
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for VENTX

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

VENTX for domains About GeneDecksing

3 InterPro domains/families:

IPR017970 Homeobox_CS

IPR001356 Homeodomain

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry O95231

ProtoNet protein and cluster: O95231

UniProtKB/Swiss-Prot: VENTX_HUMAN, O95231

Similarity: Contains 1 homeobox DNA-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: VENTX_HUMAN, O95231

Function: May be involved in ventralization

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

VENTX for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for VENTX

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VENTX
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate VENTX
		SwitchGear 3'UTR luciferase reporter plasmid: VENTX 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VENTX OriGene shRNA RFP: VENTX OriGene siRNA: VENTX
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VENTX
		Sirion Biotech Custom design and validation of potent shRNA sequences against VENTX

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for VENTX
			Sirion Biotech Customized adenovirus for overexpression of VENTX Sirion Biotech Customized adenovirus for potent knockdown of VENTX

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: VENTX (NM_014468)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VENTX
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VENTX

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for VENTX
		Search LifeMap BioReagents cell lines for VENTX
		Sirion Biotech Customized stable knockdown cell line services for VENTX Sirion Biotech Customized inducible knockdown cell line services for VENTX Sirion Biotech Customized stable overexpressing cell line services for VENTX Sirion Biotech Customized inducible overexpressing cell line services for VENTX

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VENTX

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for VENTX

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for VENTX (O95231³ ENSP00000357556⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IRF9	Q00978³, ENSP00000380073⁴	I2D: score=1 STRING: ENSP00000380073
TLE1	Q04724³, ENSP00000365682⁴	I2D: score=1 STRING: ENSP00000365682
TLE2	Q04725³, ENSP00000262953⁴	I2D: score=1 STRING: ENSP00000262953

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	IEA	--

VENTX for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for VENTX
Search CenterWatch for drugs/clinical trials and news about VENTX

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for VENTX gene:

NM_014468.2

Unigene Cluster for VENTX:

VENT homeobox

Hs.125231 [show with all ESTs]

Unigene Representative Sequence: AF068006

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000325980(uc010quy.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VENTX
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate VENTX
		SwitchGear 3'UTR luciferase reporter plasmid: VENTX 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VENTX OriGene shRNA RFP: VENTX OriGene siRNA: VENTX
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VENTX
		Sirion Biotech Custom design and validation of potent shRNA sequences against VENTX

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: VENTX (NM_014468)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VENTX
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VENTX

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VENTX Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat VENTX
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VENTX
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VENTX

Additional cDNA sequence:

AF068006.1 BC108915.1 BC108916.1

1 DOTS entry:

DT.95220313

9 AceView cDNA sequences:

NM_014468 AA973729 CA390754 AF068006 BM676533 BX089390 W37703 AA872096

W37326

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

VENTX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

VENTX expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Line H9 (WA09) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See VENTX Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VENTX

SOURCE GeneReport for Unigene cluster: Hs.125231

UniProtKB/Swiss-Prot: VENTX_HUMAN, O95231

Tissue specificity: Expressed in bone marrow of patients recovering from chemotherapy. Also expressed in an

erythroleukemia cell line

SABiosciences Custom PCR Arrays for VENTX

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VENTX Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat VENTX
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VENTX
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VENTX

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VENTX

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for VENTX gene from 5/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	VENTX⁶	--	36(a)	1 ↔ 1	Un(48526824-48527651)
lizard (Anolis carolinensis)	Reptilia	-- --	--	50(a) 26(a)	many → 1 many → 1	GL343262.1(400132-402428) GL343262.1(342148-346774)
African clawed frog (Xenopus laevis)	Amphibia	U43938.1²	--	73.74(n)		U43938.1
zebrafish (Danio rerio)	Actinopterygii	vent⁶ vox⁶	ventral homeobox	30(a) 21(a)	many → 1 many → 1	13(54056772-54063429) 13(54046956-54049197)
worm (Caenorhabditis elegans)	Secernentea	ceh-7⁶ C02F12.10⁶	--	42(a) 26(a)	1 ↔ 1 possible ortholog	II(8703318-8703779) X(3672264-3673905)

Species with no ortholog for VENTX

ENSEMBL Gene Tree for VENTX (if available)
TreeFam Gene Tree for VENTX (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for VENTX gene

1 SIMAP similar gene for VENTX using alignment to 1 protein entry: VENTX_HUMAN:

VENTX1

VENTX for paralogs About GeneDecksing

5/7 Pseudogenes.org Pseudogenes for VENTX (see all 7)
PGOHUM00000239855 PGOHUM00000248448 PGOHUM00000237560 PGOHUM00000237957 PGOHUM00000249291

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181710072^1,2		--	135049438(+)	`GTGGGA/GGTGCT`	1	--	us2k¹		0	--	--	--	--
rs187130050^1,2		--	135049486(+)	`TGGGCC/TCCGGA`	1	--	us2k¹		0	--	--	--	--
rs191815266^1,2		--	135049574(+)	`GGAAGC/TTTCTG`	1	--	us2k¹		0	--	--	--	--
rs140875724^1,2		--	135049589(+)	`TTTTCC/TCTGCC`	1	--	us2k¹		0	--	--	--	--
rs2980715^1,2	H	--	135049984(+)	`AACCAG/AGGTCA`	1	--	us2k¹		4		NS EA	414
rs2980716^1,2	C,H	--	135050061(+)	`GCTGAG/AGTCCC`	1	--	us2k¹		4		NS EA	418
rs3763770^1,2	F,H	--	135050113(-)	`AGCCTC/ACCGGG`	1	--	us2k¹		4		NS EA	420
rs117990204^1,2		--	135050159(+)	`CCCGCC/TGGTCT`	1	--	us2k¹		1		EA	120
rs35772810^1,2	F	--	135050287(-)	`GCGCAG/TGTCCG`	1	--	us2k¹		1		NA	6
rs2980717^1,2	C,F,H	--	135050478(+)	`GAGCAG/ACGGCC`	1	--	us2k¹		6		NS EA NA	414

HapMap Linkage Disequilibrium report for VENTX (135051175 - 135055433 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for VENTX
10 CNVs: 29878 2896 4723 4721 30525 5272 29879 4722 5273 3829

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VENTX

DNA2.0 Custom Variant and Variant Library Synthesis for VENTX

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

VENTX for disorders           About GeneDecksing

OMIM gene information: 607158    OMIM disorders: --

4 diseases for VENTX:    About MalaCards

melanoma acute myeloid leukemia myeloid leukemia leukemia

Export disorders for VENTX gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for VENTX gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with VENTX)

Utopia: connect your pdf to the dynamic
world of online information

A processed pseudogene codes for a new antigen recognized by a CD8(+) T cell clone on melanoma. (PubMed id 10790436)^{1, 3, 9} Moreau-Aubry A.... Breathnach R. (2000)
Molecular cloning of a human Vent-like homeobox gene. (PubMed id 11549314)^{1, 2} Moretti P.A.B....D'Andrea R.J. (2001)
Suppression of homeobox transcription factor VentX pro motes expansion of human hematopoietic stem/multipotent progenitor cells. (PubMed id 22791709)¹ Gao H....Zhu Z. (2012)
VentX trans-activates p53 and p16ink4a to regulate ce llular senescence. (PubMed id 21325273)¹ Wu X....Zhu Z. (2011)
The homeobox transcription factor VentX controls huma n macrophage terminal differentiation and proinflammatory activation. (PubMed id 21670496)¹ Wu X....Zhu Z. (2011)
VentX, a novel lymphoid-enhancing factor/T-cell facto r-associated transcription repressor, is a putative tumor suppressor. (PubMed id 20028861)¹ Gao H....Zhu Z. (2010)
The vent-like homeobox gene VENTX promotes human myel oid differentiation and is highly expressed in acute myeloid leukemia. (PubMed id 20833819)¹ Rawat V.P....Feuring-Buske M. (2010)
An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)¹ Ravasi T....Hayashizaki Y. (2010)
Classification and nomenclature of all human homeobox genes. (PubMed id 17963489)¹ Holland P.W.H.... Bruford E.A. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 27287	HGNC: 13639	AceView: VENTX2	Ensembl:ENSG00000151650	euGenes: HUgn27287
ECgene: VENTX	H-InvDB: VENTX

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for VENTX	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for VENTX	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for VENTX gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for VENTX gene:
Search GeneIP for patents involving VENTX

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for VENTX
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VENTX		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VENTX
	OriGene Protein Over-expression Lysate for VENTX		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for VENTX		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VENTX
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for VENTX		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for VENTX		OriGene Custom Protein Services for VENTX
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VENTX
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VENTX
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VENTX
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VENTX
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VENTX
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VENTX

	GenScript Custom Purified and Recombinant Proteins Services for VENTX		GenScript cDNA clones with any tag delivered in your preferred vector for VENTX
	GenScript Custom Assay Services for VENTX		GenScript Custom Superior Antibodies Services for VENTX
	GenScript Custom overexpressing Cell Line Services for VENTX		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in VENTX promoter
	Search Chromatin IP Primers for VENTX
	RT² qPCR Primer Assay in human, mouse / rat VENTX
	Search GNC Networks for VENTX
	SABiosciences Custom PCR Arrays for VENTX

Search Tocris compounds for VENTX

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	VENTX antibodies
	VENTX proteins
	VENTX lysates

	Antibodies for VENTX
	See all of Abcam's Antibodies, Kits and Proteins for VENTX
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

VENTX Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for VENTX

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VENTX

	SwitchGear 3'UTR luciferase reporter plasmids for VENTX
	SwitchGear Promoter luciferase reporter plasmids for VENTX

ThermoFisher Antibodies for VENTX

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VENTX

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for VENTX

Sirion Biotech Customized:

	stable knockdown cell line services for VENTX
	inducible knockdown cell line services for VENTX
	design and validation of potent shRNA sequences against VENTX
	adenovirus for potent knockdown of VENTX
	adenovirus for overexpression of VENTX
	stable overexpressing cell line services for VENTX
	inducible overexpressing cell line services for VENTX

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes VENTX gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

VENTX Gene

VENT homeobox

Aliases
for VENTX gene

Summaries
for VENTX gene

Genomic Views
for VENTX gene

Proteins
for VENTX gene

Protein Domains /
Families
for VENTX gene

Function
for VENTX gene

Pathways & Interactions
for VENTX gene

Drugs & Compounds
for VENTX gene

Transcripts
for VENTX gene

Expression
for VENTX gene

Orthologs
for VENTX gene

Paralogs
for VENTX gene

Genomic Variants
for VENTX gene

Disorders / Diseases
for VENTX gene

Publications
for VENTX gene

External Searches for VENTX gene

Genome Databases showing VENTX gene

Other Databases showing VENTX gene

Specialized Databases showing VENTX gene

Intellectual Property
for VENTX gene

Products
for VENTX gene

View Random Gene

Advanced Search

Export list of displayed genes

VENTX Gene

VENT homeobox

Aliasesfor VENTX gene

Summariesfor VENTX gene

Genomic Viewsfor VENTX gene

Proteinsfor VENTX gene

Protein Domains /Familiesfor VENTX gene

Functionfor VENTX gene

Pathways & Interactionsfor VENTX gene

Drugs & Compoundsfor VENTX gene

Transcriptsfor VENTX gene

Expression for VENTX gene

Orthologsfor VENTX gene

Paralogsfor VENTX gene

Genomic Variantsfor VENTX gene

Disorders / Diseasesfor VENTX gene

Publicationsfor VENTX gene

External Searches for VENTX gene

Genome Databases showing VENTX gene

Other Databases showing VENTX gene

Specialized Databases showing VENTX gene

Intellectual Propertyfor VENTX gene

Productsfor VENTX gene

View Random Gene

Aliases
for VENTX gene

Summaries
for VENTX gene

Genomic Views
for VENTX gene

Proteins
for VENTX gene

Protein Domains /
Families
for VENTX gene

Function
for VENTX gene

Pathways & Interactions
for VENTX gene

Drugs & Compounds
for VENTX gene

Transcripts
for VENTX gene

Expression
for VENTX gene

Orthologs
for VENTX gene

Paralogs
for VENTX gene

Genomic Variants
for VENTX gene

Disorders / Diseases
for VENTX gene

Publications
for VENTX gene

Intellectual Property
for VENTX gene

Products
for VENTX gene