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VEGFB Gene

protein-coding GIFtS: 68

GC11P063758

vascular endothelial growth factor B
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: VRF)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
VEGF-B ^³
VEGFL ^¹, ²
VRF ^², ³, ⁵

Descriptions
VEGF-related factor ^³
vascular endothelial growth factor B ^²

External Ids
HGNC: 12681¹
Entrez Gene: 7423²
UniProtKB: P49765³
Ensembl: ENSG00000173511⁷

Search outside databases for aliases for VEGFB gene

Previous GC identifers: GC11P066518 GC11P065683 GC11P064253 GC11P063777

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: VEGFB_HUMAN, P49765

Function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the

binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis

Gene Wiki entry for VEGFB (Vascular_endothelial_growth_factor_B)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the VEGFB gene

Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13

VEGFB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P063758: (about GC identifiers)

Start:	63,758,842 bp from pter
End:	63,762,835 bp from pter
Size:	3,994 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: VEGFB_HUMAN, P49765 (See protein sequence)

Recommended Name: Vascular endothelial growth factor B precursor

Size: 207 amino acids; 21602 Da

Subunit: Homodimer; disulfide-linked. Can also form heterodimer with VEGF

Subcellular location: Secreted. Note=Secreted but remains associated to cells or to the

extracellular matrix unless released by heparin

PDB structure from and Proteopedia :

2C7W (3D)

2VWE (3D)

Secondary accessions: Q16528

Alternative splicing: 2 isoforms: P49765-1 P49765-2 (Additional isoforms seem to exist)

Post-translational modifications:

VEGF-B186 is O-glycosylated (By similarity)¹

REFSEQ proteins: NP_003368.1

ENSEMBL proteins:

ENSP00000311127

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for VEGFB (VEGF-B)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (VEGFB 167, VEGFB, VEGFB 186)
	Human Recombinant Proteins from Abnova (VEGFB)

OriGene Purified Recombinant Human Protein: VEGFB

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	NAS	8919691
GO:0016020	membrane	IEA	--
GO:0031093	platelet alpha granule lumen	EXP	9684805

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Antibodies for VEGFB:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for VEGFB
	R&D Systems Antibodies for VEGFB (VEGF-B)
	Cell Signaling Technology (CST) Antibodies for VEGFB (VEGF-B)
	Antibodies from Abcam (VEGFB 167, VEGFB, VEGFB 186), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (VEGFB)
	Novus Biologicals Antibodies for VEGFB

Assays for VEGFB:

	Browse Invitrogen for biochemical assays
	Millipore Kits and Assays for the Analysis of VEGFB
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P49765

ProtoNet protein and cluster: P49765

2 Blocks protein families:

IPB000072 Platelet-derived growth factor (PDGF)

IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: VEGFB_HUMAN, P49765

Similarity: Belongs to the PDGF/VEGF growth factor family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (VEGFB)
		Millipore RNAi Products for the Analysis of VEGFB Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (VEGFB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003377

Applied Biosystems Silencer® siRNAs for VEGFB

Sigma-Aldrich siRNA and siRNA Panels for VEGFB

Sigma-Aldrich shRNA Panels and shRNA for VEGFB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for VEGFB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003377
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003377
untagged cDNA clone in CMV expression vector: NM_003377

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003377

UniProtKB/Swiss-Prot: VEGFB_HUMAN, P49765

Function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the

binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis

Genatlas biochemistry entry for VEGFB:

vascular endothelial growth factor B,with two alternatively spliced forms differing at their C

terminal,universally expressed,PDGF family,hypoxia-inducible,involved in

vasculogenesis,downregulated by VHL

3 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Vegfb):

homeostasis/metabolism

vision/eye

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005172	vascular endothelial growth factor receptor binding	NAS	8919691
GO:0005515	protein binding	IEA	--
GO:0008083	growth factor activity	IEA	--
GO:0008201	heparin binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/10 Sigma-Aldrich "Your Favorite Gene" Pathways for VEGFB (Your Favorite Gene powered by Ingenuity) (see all 10 )

Axonal Guidance Signaling
Amyotrophic Lateral Sclerosis Signaling
Ephrin Receptor Signaling
Nitric Oxide Signaling in the Cardiovascular System
HIF1&alpha

GeneDecks VEGFB for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for VEGFB

5/22 Interacting proteins for VEGFB (ENSP00000311127³) via UniProtKB, MINT, and/or STRING (see all 22 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FLT1	ENSP00000282397³	STRING (score=.998)
NRP1	ENSP00000364001³	STRING (score=.997)
PDGFC	ENSP00000274071³	STRING (score=.921)
FIGF	ENSP00000297904³	STRING (score=.92)
VEGFC	ENSP00000280193³	STRING (score=.916)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001558	regulation of cell growth	NAS	8919691
GO:0007165	signal transduction	TAS	8637916
GO:0008284	positive regulation of cell proliferation	TAS	8637916

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for VEGFB

Sigma-Aldrich Small Molecules for VEGFB:

Inhibitor

Browse Tocris compounds for VEGFB
2 Novoseek chemical compound relationships for VEGFB gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	48.51	9	15032727 (1), 11306510 (1), 12888864 (1), 18794121 (1) (see all 8)
oxygen	0.00	1	10575000 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (VEGFB)
		Millipore RNAi Products for the Analysis of VEGFB Gene knock-down
		Abnova Chimera RNAi Products for Gene knock-down (VEGFB)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003377

Sigma-Aldrich siRNA and siRNA Panels for VEGFB

Sigma-Aldrich shRNA Panels and shRNA for VEGFB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003377

REFSEQ mRNAs for VEGFB gene:

NM_003377.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003377

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003377
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003377
                                 untagged cDNA clone in CMV expression vector: NM_003377

Additional cDNA sequence:

BC008818.2 CR602359.1 U43368.1 U43369.1 U48801.1 U52819.1

5 DOTS entries:

DT.456113 DT.92325533 DT.97845793 DT.95139285 DT.91745181

24/174 AceView cDNA sequences (see all 174 ):

BM694361 AA742966 BI962562 BU736807 U43369 CB155272 BG031449 AA746258

U43368 BM701452 BC008818 BM704880 R29477 T08411 AA400486 NM_003377

CR602359 AI687256 BQ009854 BM705235 BQ011717 AA419103 AI300509 CD671140

highest scoring ESTs for VEGFB:

U43368 U48801 AA040199 AA040843 AA082818 AA182397 AA304346 AA310070 AA352350 AA400486

Unigene Cluster for VEGFB:

Vascular endothelial growth factor B

Hs.78781 [show with all ESTs]

Unigene Representative Sequence: BM546651

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for VEGFB

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7a	·	7b
SP1:
SP2:											-

About this scheme

ECgene alternative splicing isoforms for VEGFB

1 Ensembl transcript including schematic representation:

ENST00000309422

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

VEGFB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for VEGFB

¹ / ² / ³

4 probe-sets matching VEGFB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37268_at²^{, 3}	U95-A	1	1.00	1.00	0.96	1.19	U43368	1.00	1.00	1.00	1
1926_at²^{, 3}	U95-A	2	1.00	0.97	0.98	0.81	U48801	1.00	1.00	1.00	1
203683_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003377	0.60	1.00	0.82	1
203683_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks VEGFB for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCTTTTCAGA

SOURCE GeneReport for Unigene cluster: Hs.78781
Expression variation in blood from EXPOLDB for VEGFB
UniProtKB/Swiss-Prot: VEGFB_HUMAN, P49765
Tissue specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal
muscle and pancreas

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for VEGFB gene from 1 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
mouse (Mus musculus)	Vegfb^{1, 5}	19⁵	vascular endothelial growth factor B^{1, 5}	89.69(n)¹ 86.96(a)¹	22340¹ NM_011697.2¹ NP_035827.1¹ AK148188⁵ AK178982⁵ (see all 20)

About this table Species with no ortholog for VEGFB

ENSEMBL Gene Tree for VEGFB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for VEGFB gene

VEGFC² PGF² FIGF² VEGFA²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/47 NCBI SNPs in VEGFB are shown (see all 47 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 52)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs594942^1,2	A,C,F,H	63762868(-)	`CCTGGG/ACAGTG`	1	--	ng3¹		13		NA EU EA WA	1144
	rs2302260^1,2	C,F	63761369(-)	`AAAAGG/AGAAAG`	1	--	int¹		2		EA	1474
	rs11603042^1,2	C	63760419(+)	`GGCTTG/TGGGGG`	1	--	int¹		0	--	--	--	--
	rs61761278^1,2	--	63762662(+)	`CACATA/GCCAGC`	1	--	ut3¹		0	--	--	--	--
--	rs61384522^1,2	--	63761684(+)	`TAGAGC/TTCAAC`	1	--	ut3¹		0	--	--	--	--
--	rs61761279^1,2	--	63762922(+)	`CTTGTC/TTTGCT`	1	--	ng3¹		0	--	--	--	--
--	rs61761267^1,2	--	63760010(+)	`CTGACA/GATGGC`	1	D/N	mis¹		0	--	--	--	--
--	rs61761277^1,2	--	63762652(+)	`CAAGAA/GGGGTC`	1	--	ut3¹		0	--	--	--	--
--	rs12366035^1,2	--	63761268(+)	`CCAGAC/TAGGTG`	1	D/D	syn¹ ese³		0	--	--	--	--
--	rs55896476^1,2	--	63759946(+)	`GGCACC/TGTGGC`	1	T/T	syn¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for VEGFB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601398

10/28 Novoseek disease relationships for VEGFB gene (see all 28 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neovascularization	62.42	8	15032727 (1), 18930733 (1), 19369214 (1), 16407796 (1) (see all 5)
metastasis	39.54	15	12866573 (4), 10873096 (2), 11241411 (2), 11505400 (1) (see all 8)
tumors	39.22	37	9665470 (4), 15107801 (3), 18537151 (2), 10815914 (2) (see all 17)
hnscc	27.72	1	11505400 (1)
cancer	25.58	1	15664381 (1)
adenocarcinoma lung	20.34	1	10873096 (1)
glioblastoma	19.25	2	12622137 (2)
primary tumor	19.03	2	10815914 (1), 15107801 (1)
carcinoma papillary	19.00	1	11306510 (1)
pancreatic carcinoma	16.87	1	15952180 (1)

About this table

Human Genome Epidemiology Navigator: VEGFB (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/140 PubMed articles for VEGFB gene (see all 140 ):

Vascular endothelial growth factor B, a novel growth factor for endothelial cells. (PubMed id 8637916)^{1, 2, 3, 4} Olofsson B.... Eriksson U. (1996)
Cloning and characterization of a novel human gene related to vascular endothelial growth factor. (PubMed id 8919691)^{1, 2, 3, 4} Grimmond S....Weber G. (1996)
Crystal structure of human vascular endothelial growth factor-B: identification of amino acids important for receptor binding. (PubMed id 16616187)^{1, 3, 4} Iyer S....Ravi Acharya K. (2006)
Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform. (PubMed id 8702615)^{1, 3, 4} Olofsson B....Eriksson U. (1996)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment. (PubMed id 18930733)^{1, 3} Leonard P....Acharya K.R. (2008)
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. (PubMed id 9751730)^{1, 3} Olofsson B....Eriksson U. (1998)
Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters. (PubMed id 18537151)^{1, 3} Kanda M....Nakao A. (2008)
Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1. (PubMed id 10409677)^{1, 3} Makinen T....Alitalo K. (1999)
Comparative expression of vascular endothelial growth factor family members, VEGF-B, -C and -D, by normal human keratinocytes and fibroblasts. (PubMed id 15009103)^{1, 3} Trompezinski S....Viac J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7423	HGNC: 12681	AceView: VEGFB	Ensembl:ENSG00000173511	euGenes: HUgn7423
ECgene: VEGFB	H-InvDB: VEGFB

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for VEGFB	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for VEGFB
(Available from WIS Yeda, Salk, Tufts)

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Licensable Technologies for VEGFB gene:

Weizmann Institute:

Porphyrin and Corrole -like analogs as potent inhibitors of Growth Factor Receptor Binding and Activation

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for VEGFB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for VEGFB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for VEGFB		Antibodies for VEGFB
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for VEGFB		Small molecules for VEGFB
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (VEGFB)
	Antibodies (VEGFB)
	Chimera RNAi (VEGFB)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for VEGFB (VEGF-B)

	Recombinant Proteins (VEGFB 167, VEGFB, VEGFB 186)
	Antibodies (VEGFB 167, VEGFB, VEGFB 186)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for VEGFB

	Drugs for VEGFB
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for VEGFB

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
VEGFB Gene at Home site.
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VEGFB Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for VEGFB

Summaries
for VEGFB

Genomic Location
for VEGFB

Proteins
for VEGFB

Protein Domains/
Families
for VEGFB

Gene Function
for VEGFB

Pathways & Interactions
for VEGFB

Drugs & Compounds
for VEGFB

Transcripts
for VEGFB

Expression
for VEGFB

Orthologs
for VEGFB

Paralogs
for VEGFB

SNPs/Variants
for VEGFB

Disorders & Mutations
for VEGFB

Medical News
for VEGFB

Publications
for VEGFB

Search for VEGFB

Genome Databases showing VEGFB

Other Databases showing VEGFB

Specialized Databases showing VEGFB

Licensable Technologies
for VEGFB

Services
for VEGFB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

VEGFB Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor VEGFB

Summariesfor VEGFB

Genomic Locationfor VEGFB

Proteinsfor VEGFB

Protein Domains/Familiesfor VEGFB

Gene Functionfor VEGFB

Pathways & Interactionsfor VEGFB

Drugs & Compoundsfor VEGFB

Transcriptsfor VEGFB

Expression for VEGFB

Orthologsfor VEGFB

Paralogsfor VEGFB

SNPs/Variantsfor VEGFB

Disorders & Mutationsfor VEGFB

Medical Newsfor VEGFB

Publicationsfor VEGFB

Search for VEGFB

Genome Databases showing VEGFB

Other Databases showing VEGFB

Specialized Databases showing VEGFB

Licensable Technologiesfor VEGFB

Servicesfor VEGFB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for VEGFB

Summaries
for VEGFB

Genomic Location
for VEGFB

Proteins
for VEGFB

Protein Domains/
Families
for VEGFB

Gene Function
for VEGFB

Pathways & Interactions
for VEGFB

Drugs & Compounds
for VEGFB

Transcripts
for VEGFB

Expression
for VEGFB

Orthologs
for VEGFB

Paralogs
for VEGFB

SNPs/Variants
for VEGFB

Disorders & Mutations
for VEGFB

Medical News
for VEGFB

Publications
for VEGFB

Licensable Technologies
for VEGFB

Services
for VEGFB