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Aliases & Descriptions for VCY
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| BPY1 1, 2, 3, 5 | | BPY1B 3 | | MGC119817 2 | | VCY1 1, 2 | | VCY1A 1, 2, 3 |
| | | Descriptions |
|---|
| Basic charge, Y-linked 1 3 | | Variably charged protein Y 3 | | basic protein on Y chromosome, 1 2 | | testis-specific basic protein on Y, 1 2 | | variable charge, Y chromosome 1, 2 | | variable charge, Y-linked 2 |
|
| | Search outside databases for aliases for VCY genePrevious GC identifers: GC0YP015485 GC0YM015407 GC0YM015106 |
Summaries for VCY(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for VCY: The protein encoded by this gene is a member of a family of human VCX/Y genes. This gene family has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. Members of the VCX/Y family share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. VCX/Y genes encode small and highly charged proteins of unknown function. This gene encodes a small, positively charged protein. The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq] UniProtKB/Swiss-Prot: VCY1_HUMAN, O14598Function: May mediate a process in spermatogenesis or may play a role in sex ratio distortion |
Genomic Location for VCY
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the VCY gene 
Entrez Gene cytogenetic band: Yq11.221 Ensembl cytogenetic band: Yq11.221 HGNC cytogenetic band: Yq11.221VCY Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome Y GeneLoc Exon Structure GeneLoc location for GC0YP014607:
(about GC identifiers)
Start:
|
14,677,492 bp from pter |
End:
|
14,678,234 bp from pter |
Size:
|
743 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000024.8 NT_011875.11
| Proteins for VCY
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: VCY1_HUMAN, O14598 (See
protein sequence)Recommended Name: Testis-specific basic protein Y 1 Size: 125 amino acids; 12917 DaREFSEQ proteins: NP_004670.1
ENSEMBL proteins: ENSP00000250823
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for VCY: Assays for VCY: | Protein
Domains/ Families for VCY(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: O14598 UniProtKB/Swiss-Prot: VCY1_HUMAN, O14598Similarity: Belongs to the VCX/VCY family | Gene Function for VCY
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004679
Applied Biosystems Silencer® siRNAs for VCY
Sigma-Aldrich siRNA for VCY  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004679                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004679                                  untagged cDNA clone in CMV expression vector: NM_004679 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_004679
UniProtKB/Swiss-Prot: VCY1_HUMAN, O14598Function: May mediate a process in spermatogenesis or may play a role in sex ratio distortionGenatlas biochemistry entry for VCY:variable charge X/Y,basic protein on chromosome Y,1,testis specific,in a AZF deleted region | Pathways & Interactions for VCY
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| -- |
Drugs & Compounds for VCY(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for VCY
|
Transcripts for VCY(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004679
Sigma-Aldrich siRNA for VCY  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_004679 REFSEQ mRNAs for VCY gene: NM_004679.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_004679               OriGene GFP tagged cDNA clone in CMV expression vector: NM_004679                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004679                                  untagged cDNA clone in CMV expression vector: NM_004679  Additional cDNA sequence: AF000979.1 BC096729.1 2 DOTS entries: DT.120654203 DT.443460 24/43 AceView cDNA sequences (see all 43
):BF508070 AF000979 AI650513 BF478074 AI917448 AW193704 NM_181880 BF059317 AI672566 AI634041 AA759284 AI917301 BC056508 NM_004679 AA496066 AI809663 AW196662 AI809702 AI621240 AA393129 AI611655 BX281130 AW303648 AI963982
highest scoring ESTs for VCY:AF000979 AA609921 AI149997 NM_004679 BC096729 AI633259 XM_379695 AA406064 AA621737 AA635143 Unigene Cluster for VCY: Variable charge, Y-linked Hs.632284 [show with all ESTs]Unigene Representative Sequence: AF000979
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000250823
|
Expression for VCY
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| VCY expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for VCY
1 / 2 / 3 3 probe-sets matching VCY gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.632284
Expression variation in blood from EXPOLDB for VCY UniProtKB/Swiss-Prot: VCY1_HUMAN, O14598Tissue specificity: Expressed exclusively in testis |
Orthologs for VCY
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for VCY | Paralogs for VCY(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for VCY gene
- VCY1B1 2 VCX3B2 VCX2 VCX22 VCX3A2 ENSG000002149502
|
SNPs/Variants for VCY(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations for VCY
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 400012
|
Medical News for VCY(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for VCY (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 6 PubMed articles for VCY gene: |
Search for VCY
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing VCY
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing VCY
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VCY(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for VCY(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for VCY:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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