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Aliases &
Descriptions
for VCX3B
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| MGC119815 2 | | VCX-C 1, 2, 3 | | VCXC 3 |
| | | Descriptions |
|---|
| Variably charged protein X-C 3 | | variable charge, X-linked 3B 2 | | variably charged X-C 2 |
|
| |
Search outside databases for aliases for VCX3B genePrevious GC identifer: GC0XU900564 |
Summaries
for VCX3B(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for VCX3B:
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes,
and all are expressed exclusively in male germ cells. The X-linked members are clustered on
chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic
region on Yq11. The family members share a high degree of sequence identity, with the exception
that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked
members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may
have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of
unknown function. The presence of a putative bipartite nuclear localization signal suggests that
VCX/Y members are nuclear proteins. This gene contains 11 repeats of the 30-bp unit. [provided by
RefSeq]
UniProtKB/Swiss-Prot: VCX3B_HUMAN, Q9H321Function: May mediate a process in spermatogenesis or may play a role in sex ratio distortion |
Genomic Location
for VCX3B
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22.31 Ensembl cytogenetic band: Xp22.31 HGNC cytogenetic band: Xp22.31VCX3B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP008393:
(about GC identifiers)
Start:
|
8,392,871 bp from pter |
End:
|
8,394,551 bp from pter |
Size:
|
1,681 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011757.15
| Proteins
for VCX3B
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: VCX3B_HUMAN, Q9H321 (See
protein sequence)Recommended Name: Variable charge X-linked protein 3B Size: 216 amino acids; 23494 Da
Secondary accessions: Q4KN12REFSEQ proteins: NP_001001888.2
ENSEMBL proteins: ENSP00000370420 ENSP00000370417
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for VCX3B:
Assays for VCX3B: | Protein
Domains/
Families
for VCX3B(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9H321 UniProtKB/Swiss-Prot: VCX3B_HUMAN, Q9H321Similarity: Belongs to the VCX/VCY family | Gene Function
for VCX3B
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001001888
 Applied Biosystems Silencer® siRNAs for VCX3B
 Sigma-Aldrich siRNA for VCX3B
Sigma-Aldrich shRNA for VCX3B
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001001888
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001001888
untagged cDNA clone in CMV expression vector: NM_001001888
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001001888
UniProtKB/Swiss-Prot: VCX3B_HUMAN, Q9H321Function: May mediate a process in spermatogenesis or may play a role in sex ratio distortion | Pathways & Interactions
for VCX3B
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
2 Interacting proteins for VCX3B (ENSP000003704203) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007283 | spermatogenesis |
ISS | -- |
About this table
|
Drugs & Compounds
for VCX3B(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for VCX3B
|
Transcripts
for VCX3B(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001001888
Sigma-Aldrich siRNA for VCX3B
Sigma-Aldrich shRNA for VCX3B
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001001888 REFSEQ mRNAs for VCX3B gene: NM_001001888.2
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001001888
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001001888
untagged cDNA clone in CMV expression vector: NM_001001888
Additional cDNA sequence: AF167080.2 BC098143.1 1 DOTS entry: DT.95160672 Unigene Cluster for VCX3B: Variable charge, X-linked 3B Hs.534814 Unigene Representative Sequence: AF167080
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000381032
ENST00000381029
|
Expression
for VCX3B
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| VCX3B expression in normal and diseased human tissues
1 / 2 2 probe-sets matching VCX3B gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.534814
UniProtKB/Swiss-Prot: VCX3B_HUMAN, Q9H321Tissue specificity: Expressed exclusively in testis |
Orthologs
for VCX3B
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for VCX3B | Paralogs
for VCX3B(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for VCX3B gene
- VCX3A1 2 VCX1 2 VCY2 VCX22 ENSG000002149502 VCY1B2
|
SNPs/Variants
for VCX3B(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for VCX3B (up to first 250kb)
|
Disorders & Mutations
for VCX3B
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for VCX3B(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for VCX3B (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 5 PubMed articles for VCX3B gene: |
Search for VCX3B
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VCX3B
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing VCX3B
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VCX3B(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for VCX3B(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for VCX3B:
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