Aliases for VCX Gene
External Ids for VCX Gene
Previous GeneCards Identifiers for VCX Gene
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
GeneCards Summary for VCX Gene
VCX (Variable Charge, X-Linked) is a Protein Coding gene. Diseases associated with VCX include Non-Syndromic X-Linked Intellectual Disability. GO annotations related to this gene include chromatin binding. An important paralog of this gene is VCX3B.
UniProtKB/Swiss-Prot for VCX Gene
May mediate a process in spermatogenesis or may play a role in sex ratio distortion.