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VCPIP1 Gene

protein-coding   GIFtS: 50
GCID: GC08M067540

Valosin Containing Protein (P97)/P47 Complex Interacting...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Valosin Containing Protein (P97)/P47 Complex Interacting Protein 11 2     DUBA32
Valosin-Containing Protein P97/P47 Complex-Interacting Protein 12 3     Deubiquitinating Protein VCIP1352
Valosin-Containing Protein P97/P47 Complex-Interacting Protein P1352 3     Valosin-Containing Protein (P97)/P47 Complex-Interacting Protein P1352
VCIP1352 3     EC 3.4.19.123
VCP/P47 Complex-Interacting 135-KDa Protein2 3     VCPIP1 VCIP1355
KIAA18503 5     

External Ids:    HGNC: 308971   Entrez Gene: 801242   Ensembl: ENSG000001750737   OMIM: 6117455   UniProtKB: Q96JH73   

Export aliases for VCPIP1 gene to outside databases

Previous GC identifers: GC08M067706 GC08M063032


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for VCPIP1 Gene:
VCPIP1 (valosin containing protein (p97)/p47 complex interacting protein 1) is a protein-coding gene. Diseases associated with VCPIP1 include pancreatic cancer, and pancreatitis. GO annotations related to this gene include ubiquitin-specific protease activity.

UniProtKB/Swiss-Prot: VCIP1_HUMAN, Q96JH7
Function: Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis.
May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of
the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked
polyubiquitin chains

Gene Wiki entry for VCPIP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NC_018919.2  NT_008183.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the VCPIP1 gene promoter:
         COUP-TF1   COUP   HNF-4alpha2   CUTL1   Tal-1beta   HNF-4alpha1   COUP-TF   FOXO1a   ITF-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): VCPIP1 promoter sequence
   Search Chromatin IP Primers for VCPIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VCPIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13   Ensembl cytogenetic band:  8q13.1   HGNC cytogenetic band: 8q13

VCPIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VCPIP1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M067540:  view genomic region     (about GC identifiers)

Start:
67,540,722 bp from pter      End:
67,579,452 bp from pter
Size:
38,731 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: VCIP1_HUMAN, Q96JH7 (See protein sequence)
Recommended Name: Deubiquitinating protein VCIP135  
Size: 1222 amino acids; 134321 Da
Subunit: Binds VCP and the ternary complex containing STX5A, NSFL1C and VCP (By similarity)
Sequence caution: Sequence=BAB15552.1; Type=Frameshift; Positions=1065, 1110; Sequence=BAB47479.1; Type=Erroneous
initiation;
Secondary accessions: Q504T4 Q86T93 Q86W01 Q8N3A9 Q9H5R8

Explore the universe of human proteins at neXtProt for VCPIP1: NX_Q96JH7

Explore proteomics data for VCPIP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys182, Lys199, Lys362, Lys376, Lys691, Lys729, Lys764, Lys870, Lys879, Lys1015,
                                 Lys1028
  • Modification sites at PhosphoSitePlus

  • See VCPIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079330.2  
    ENSEMBL proteins: 
     ENSP00000309031  

    VCPIP1 Human Recombinant Protein Products:

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    Novus Biologicals VCPIP1 Protein
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    Cloud-Clone Corp. Proteins for VCPIP1

    VCPIP1 Antibody Products:

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    VCPIP1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for VCPIP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for VCPIP1
    Cloud-Clone Corp. CLIAs for VCPIP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OTUD: OTU domain containing

    1 InterPro protein domain:
     IPR003323 OTU

    Graphical View of Domain Structure for InterPro Entry Q96JH7

    ProtoNet protein and cluster: Q96JH7

    1 Blocks protein domain: IPB003323 OTU-like cysteine protease

    UniProtKB/Swiss-Prot: VCIP1_HUMAN, Q96JH7
    Similarity: Contains 1 OTU domain


    VCPIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VCIP1_HUMAN, Q96JH7
    Function: Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis.
    May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of
    the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked
    polyubiquitin chains
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Number (IUBMB): EC 3.4.19.121

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004843ubiquitin-specific protease activity ISS--
         
    VCPIP1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VCPIP1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VCPIP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VCPIP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VCPIP1

    miRNA
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    miRTarBase miRNAs that target VCPIP1:
    hsa-mir-1260b (MIRT052693), hsa-mir-92a-3p (MIRT049244), hsa-mir-193b-3p (MIRT041551), hsa-mir-361-5p (MIRT044061), hsa-mir-877-3p (MIRT036959)

    Block miRNA regulation of human, mouse, rat VCPIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VCPIP1 (see all 86):
    hsa-miR-140-5p hsa-miR-26a-2* hsa-miR-642a hsa-miR-607 hsa-miR-3194-5p hsa-miR-300 hsa-miR-4272 hsa-miR-208b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    GenScript: all cDNA clones in your preferred vector: VCPIP1 (NM_025054)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VCPIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VCPIP1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VCPIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VCIP1_HUMAN, Q96JH7: Endoplasmic reticulum (By similarity). Golgi apparatus, Golgi stack (By similarity).
    Note=Associated with Golgi stacks and endoplasmic reticulum (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    endoplasmic reticulum2
    golgi apparatus2
    nucleus2
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005795Golgi stack IEA--

    VCPIP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VCPIP1
    Interactions:

        Search GeneGlobe Interaction Network for VCPIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    Selected Interacting proteins for VCPIP1 (Q96JH72, 3 ENSP000003090314) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD9O151982, 3MINT-62103 I2D: score=2 
    VCPP550723, ENSP000003517774I2D: score=3 STRING: ENSP00000351777
    FAF1Q9UNN53, ENSP000003794574I2D: score=2 STRING: ENSP00000379457
    NSFL1CQ9UNZ23, ENSP000002168794I2D: score=2 STRING: ENSP00000216879
    SVIPQ8NHG73, ENSP000003461304I2D: score=2 STRING: ENSP00000346130
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0007030Golgi organization ----
    GO:0007067mitosis IEA--
    GO:0016320endoplasmic reticulum membrane fusion IEA--
    GO:0016567protein ubiquitination ISS--

    VCPIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VCPIP1 (VCIP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for VCPIP1 gene: 
    NM_025054.4  

    Unigene Cluster for VCPIP1:

    Valosin containing protein (p97)/p47 complex interacting protein 1
    Hs.632066  [show with all ESTs]
    Unigene Representative Sequence: CR936659
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000310421(uc003xwn.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat VCPIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VCPIP1 (see all 86):
    hsa-miR-140-5p hsa-miR-26a-2* hsa-miR-642a hsa-miR-607 hsa-miR-3194-5p hsa-miR-300 hsa-miR-4272 hsa-miR-208b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat VCPIP1
    Clone
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    OriGene clones in human, mouse for VCPIP1 (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: VCPIP1 (NM_025054)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VCPIP1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for VCPIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VCPIP1
      QuantiTect SYBR Green Assays in human, mouse, rat VCPIP1
      QuantiFast Probe-based Assays in human, mouse, rat VCPIP1

    Additional mRNA sequence: 

    AB058753.1 AK026785.1 AK225580.1 AK297345.1 AL832606.2 AL834476.1 BC012498.1 BC049379.1 
    BC062426.1 BC094799.1 BC118917.1 CR936659.1 

    4 DOTS entries:

    DT.40308443  DT.100793230  DT.428776  DT.92352710 

    2 AceView cDNA sequences:

    BF377808 BF910941 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VCPIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTGTAGT
    VCPIP1 Expression
    About this image

    VCPIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VCPIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632066
        Custom PCR Arrays for VCPIP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VCPIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for VCPIP1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vcpip11 , 5 valosin containing protein (p97)/p47 complex interacting more1, 5 91.74(n)1
    95.51(a)1
      1 (2.08 cM)5
    706751  NM_173443.21  NP_775619.21 
     97186225 
    chicken
    (Gallus gallus)
    Aves VCPIP11 valosin containing protein (p97)/p47 complex interacting more 79.6(n)
    85.38(a)
      428359  NM_001012948.1  NP_001012966.1 
    lizard
    (Anolis carolinensis)
    Reptilia VCPIP16
    Uncharacterized protein
    81(a)
    1 ↔ 1
    4(30912771-30922720)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia vcpip11 valosin containing protein (p97)/p47 complex interacting more 73.15(n)
    79.12(a)
      100135732  XM_002935320.2  XP_002935366.1 
    zebrafish
    (Danio rerio)
    Actinopterygii vcpip11 valosin containing protein (p97)/p47 complex interacting more 66.01(n)
    73.55(a)
      570582  XM_694079.5  XP_699171.3 


    ENSEMBL Gene Tree for VCPIP1 (if available)
    TreeFam Gene Tree for VCPIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VCPIP1 (see all 590)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1913118751,2
    --67542045(+) GCCACA/GGCAAT 1 -- ds50010--------
    rs1809233881,2
    --67542099(+) ATTGCA/GCACTC 1 -- ds50010--------
    rs1416807391,2
    --67542126(+) ATTTCA/GTCTAG 1 -- ds50010--------
    rs1862257181,2
    --67542182(+) AACCCA/GCTTAA 1 -- ds50010--------
    rs775462691,2
    C--67542297(+) AAGCTA/GATGTG 1 -- ds50010--------
    rs1505174791,2
    --67542327(+) CAGTAC/TTAACT 1 -- ds50010--------
    rs1150750011,2
    F--67542341(+) AGTTTT/AATTAT 1 -- ds50011Minor allele frequency- A:0.05WA 118
    rs1386447311,2
    --67542357(+) TAAAAG/TAAAAC 1 -- ds50010--------
    rs1138988921,2
    C,F--67542806(+) CAACTG/AAAACT 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs1906997521,2
    --67542927(+) AATGGC/TATTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for VCPIP1 (67540722 - 67579452 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for VCPIP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv997781CNV Deletion20482838
    nsv831346CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VCPIP1
    DNA2.0 Custom Variant and Variant Library Synthesis for VCPIP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611745    OMIM disorders: --

    2 diseases for VCPIP1:    
    About MalaCards
    pancreatic cancer    pancreatitis


    VCPIP1 for disorders           About GeneDecksing


    Export disorders for VCPIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VCPIP1 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with VCPIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (Proteomics 2007)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin- containing protein/p97 during capacitation. (PubMed id 12509440)1, 3 Ficarro S....Visconti P.E. (J. Biol. Chem. 2003)
    6. VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. (PubMed id 12473691)1, 9 Uchiyama K....Kondo H. (J. Cell Biol. 2002)
    7. Mitotic phosphorylation of VCIP135 blocks p97ATPase-mediated Golgi membrane fusion. (PubMed id 23500464)1 Totsukawa G....Kondo H. (Biochem. Biophys. Res. Commun. 2013)
    8. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. (PubMed id 23827681)2 Mevissen T.E.... Komander D. (Cell 2013)
    9. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    10. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80124 HGNC: 30897 AceView: VCIP135 Ensembl:ENSG00000175073 euGenes: HUgn80124
    ECgene: VCPIP1 H-InvDB: VCPIP1

    (According to HUGE)
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    HUGE: KIAA1850

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VCPIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VCPIP1 gene:
    Search GeneIP for patents involving VCPIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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