Aliases for VBP1 Gene
External Ids for VBP1 Gene
Previous GeneCards Identifiers for VBP1 Gene
The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]
GeneCards Summary for VBP1 Gene
VBP1 (Von Hippel-Lindau Binding Protein 1) is a Protein Coding gene. Diseases associated with VBP1 include renal cell carcinoma. Among its related pathways are Transport to the Golgi and subsequent modification and Protein folding. GO annotations related to this gene include unfolded protein binding.
UniProtKB/Swiss-Prot for VBP1 Gene
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.