VAV2 Gene
protein-coding GIFtS: 64
GCID: GC09M136627
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|
vav 2 guanine nucleotide exchange factor(Previous name: vav 2 oncogene )
| |
Aliases
for VAV2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Vav 2 Guanine Nucleotide Exchange Factor1 2 | | Vav 2 Oncogene1 2 | | VAV-22 3 | | Guanine Nucleotide Exchange Factor VAV22 |
Export aliases for VAV2 gene to outside databasesPrevious GC identifers: GC09M127703 GC09M128297 GC09M130051 GC09M131970 GC09M131968 GC09M133657 GC09M135616 GC09M106127 |
Summaries
for VAV2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for VAV2:
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which isexpressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively splicedtranscript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Aug 2008)
UniProtKB/Swiss-Prot: VAV2_HUMAN, P52735Function: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role inangiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation andvascular endothelial cell migration and assembly (By similarity)
Gene Wiki entry for VAV2
|
Genomic Views
for VAV2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_035014.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the VAV2 gene promoter:
SRF AP-1 SRF (504 AA) ATF-2 STAT3 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for VAV2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAV2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.1 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q34.1VAV2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M136627: view genomic region
(about GC identifiers)
Start:
|
136,627,016 bp from pter |
End:
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136,857,726 bp from pter |
Size:
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230,711 bases |
Orientation:
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minus strand |
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Proteins
for VAV2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VAV2_HUMAN, P52735 (See
protein sequence)Recommended Name: Guanine nucleotide exchange factor VAV2 Size: 878 amino acids; 101289 Da
Subunit: Interacts (via SH2 domains) with the phosphorylated form of EPHA2 (By similarity). Interacts with NEK3 andPRLR and this interaction is prolactin-dependent
4 PDB 3D structures from  and Proteopedia  for VAV2:2DLZ (3D)
2DM1 (3D)
2LNW (3D)
2LNX (3D)
Secondary accessions: A2RUM4 A8MQ12 B6ZDF5 Q5SYV3 Q5SYV4 Q5SYV5 Q6N012 Q6PIJ9 Q6Q317Alternative splicing: 3 isoforms: P52735-1 P52735-2 P52735-3 (Contains a phosphoserine at position 769)Explore the universe of human proteins at neXtProt for VAV2: NX_P52735
Post-translational modifications:
Phosphorylated on tyrosine residues in response to FGR activation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P52735
VAV2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001127870.1 NP_003362.2
ENSEMBL proteins: ENSP00000360916 ENSP00000360917 ENSP00000385362 Reactome Protein details: P52735
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
VAV2 for ontologies About GeneDecksing
VAV2 Antibody Products:
Assay Products for VAV2: |
Protein
Domains /
Families
for VAV2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VAV2 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry P52735ProtoNet protein and cluster: P52735 5/6 Blocks protein families (see all 6): IPB000219 DH domain IPB000980 SH2 domain signature IPB001452 SH3 domain signature IPB001715 Calponin-like actin-binding IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: VAV2_HUMAN, P52735Similarity: Contains 1 CH (calponin-homology) domainSimilarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 PH domainSimilarity: Contains 1 phorbol-ester/DAG-type zinc fingerSimilarity: Contains 1 SH2 domainSimilarity: Contains 2 SH3 domains |
Function
for VAV2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VAV2_HUMAN, P52735Function: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role inangiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation andvascular endothelial cell migration and assembly (By similarity) Genatlas biochemistry entry for VAV2:VAV proto-oncogene 2,homolog,widely expressed with duplicated exons or pseudogene(s),in the same region
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for VAV2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VAV2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAV2 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
VAV2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for VAV2:
Animal Models:
Mouse knock-out Vav2tm1Tnr for VAV2
11 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Vav2):
VAV2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for VAV2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/56 super-pathways (see all 56) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development HGF signaling pathway | | | 2 | Cell death signalling via NRAGE, NRIF and NADE | | | 3 | PKC-Theta Pathway | | | 4 | Axon guidance | | | 5 | B cell receptor signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/14 EMD Millipore Pathways for VAV2 (see all 14)
5/19 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for VAV2 (see all 19)
1 
Cell Signaling Technology (CST) Pathway for VAV2
5/14  GeneGo (Thomson Reuters) Pathways for VAV2 (see all 14)
5/17  BioSystems Pathways for VAV2 (see all 17)
5/24 
Reactome Pathways for VAV2 (see all 24)
5/9 
Kegg Pathways (Kegg details for VAV2) (see all 9):
VAV2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VAV2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/190 Interacting proteins for VAV2 (P527351, 2, 3 ENSP000003609164) via UniProtKB, MINT, STRING, and/or I2D (see all 190)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ERBB2 | P046262, 3, ENSP000002695714 | MINT-74801 MINT-74800 MINT-74802 I2D:
score=2 STRING: ENSP00000269571 | | ABI1 | Q8IZP02, 3, ENSP000003653124 | MINT-7908043 MINT-7908394 I2D:
score=1 STRING: ENSP00000365312 | | NEK3 | P519561, 3, ENSP000003832104 | EBI-297549,EBI-476041 I2D:
score=2 STRING: ENSP00000383210 | | SYK | P434052, 3, ENSP000003648984 | MINT-7301412 I2D:
score=2 STRING: ENSP00000364898 | | TOM1L1 | O756741, 3, ENSP000004089584 | EBI-297549,EBI-712991 I2D:
score=1 STRING: ENSP00000408958 |
About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
VAV2 for ontologies About GeneDecksing
|
Drugs & Compounds
for VAV2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
VAV2 for compounds About GeneDecksing
 Browse Tocris compounds for VAV2
10/846 HMDB Compounds for VAV2 (see all 846) About this table
6 Novoseek chemical compound relationships for VAV2 gene About this table
Search CenterWatch for drugs/clinical trials and news about VAV2
|
Transcripts
for VAV2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VAV2 gene (2 alternative transcripts): NM_001134398.1 NM_003371.3 Unigene Clusters for VAV2: Vav 2 guanine nucleotide exchange factor Hs.369921 [show with all ESTs], Hs.689325 Unigene Representative Sequences: NM_001134398, AK1305755 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371850(uc004ces.3) ENST00000371851(uc004cer.3) ENST00000406606(uc004cet.1)
ENST00000486113 ENST00000472905
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): VAV2 (NM_003371) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VAV2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VAV2 |
Additional cDNA sequence: AK130575.1 11 DOTS entries: DT.415120 DT.101968052 DT.100755376 DT.40296426 DT.95113897 DT.121156304 DT.91663125 DT.91758100 DT.91758101 DT.95306291 DT.100728201 1 AceView cDNA sequence: AK130575
GeneLoc Exon Structure
|
Expression
for VAV2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VAV2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCACGAAGG
About this image
See VAV2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VAV2
SOURCE GeneReport for Unigene clusters: Hs.369921 Hs.689325
UniProtKB/Swiss-Prot: VAV2_HUMAN, P52735Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Array including VAV2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VAV2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VAV2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VAV2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VAV2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAV2 |
Orthologs
for VAV2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for VAV2 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
VAV21 |
vav 2 guanine nucleotide exchange factor |
83.51(n)
91.78(a) |
|
373938 NM_204142.1 NP_989473.1 |
lizard
(Anolis carolinensis) |
Reptilia |
VAV26 |
-- |
68(a) |
1 ↔ 1 |
GL343736.1(160737-211228) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC057726.12 |
-- |
78.35(n) |
|
BC057726.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
vav21 |
vav 2 guanine nucleotide exchange factor |
77.05(n)
82.29(a) |
|
556413 XM_002665976.1 XP_002666022.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
vav3 |
Rho protein signal transduction
guanyl-nucleotide more |
28(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
vav-16 |
Protein vav-1 |
24(a) |
possible ortholog |
X(9216817-9232016) |
ENSEMBL Gene Tree for VAV2 (if available)
TreeFam Gene Tree for VAV2 (if available) |
Paralogs
for VAV2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for VAV2 gene
- ARHGEF62 VAV12 PLEKHG22 PLEKHG32 PREX22 ARHGEF72 TIAM12 SPATA132
- TIAM22 ARHGEF92 VAV32 ARHGEF42 PLEKHG12 PREX12
5 SIMAP similar genes for VAV2 using alignment to 1 protein entry: VAV2_HUMAN:VAV3 SH3GL2 VAV1 CNN3 ITSN1
VAV2 for paralogs About GeneDecksing
|
Genomic Variants
for VAV2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VAV2 (136627016 - 136857726 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for VAV2
9 CNVs: 65545 70815 100797 4657 4658 100798 0132 70814 62957
6 Indels: 29071 47660 47661 47659 10813 70813 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VAV2 |
|
Disorders
/ Diseases
for VAV2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
VAV2 for disorders About GeneDecksing
OMIM gene information: 600428
OMIM disorders: --
15  diseases for VAV2: About MalaCardsangle-closure glaucoma primary angle-closure glaucoma oral squamous cell carcinoma squamous cell carcinoma
glaucoma tuberous sclerosis multiple sclerosis spasticity
pharyngitis pancreatic cancer breast cancer pancreatitis
carcinoma melanoma neuronitis
1 Novoseek disease relationship for VAV2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
3 |
11606575 (1), 19435813 (1) |
Human Genome Epidemiology (HuGE) Navigator: VAV2 (4 documents)
Export disorders for VAV2 gene to outside databases
|
Publications
for VAV2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VAV2 gene, integrated from 9 sources (see all 100):
(articles sorted by number of sources associating them with VAV2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1. (PubMed id 7762982)1, 2, 3 Henske E.P.... Kwiatkowski D.J. (1995)
- Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac. (PubMed id 12454019)1, 2, 9 Tamas P.... Buday L. (2003)
- Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor. (PubMed id 15618286)1, 2, 9 Miller S.L....Clevenger C.V. (2005)
- Vav2 is required for cell spreading. (PubMed id 11448999)1, 9 Marignani P.A. and Carpenter C.L. (2001)
- Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor. (PubMed id 11516622)1, 9 Tamas P....Buday L. (2001)
- Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte. (PubMed id 11262396)1, 9 Tartare-Deckert S....Deckert M. (2001)
- Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes. (PubMed id 11080163)1, 9 Doody G.M....Turner M. (2000)
- Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. (PubMed id 10982832)1, 9 Liu B.P. and Burridge K. (2000)
- VAV2 regulates epidermal growth factor receptor endoc ytosis and degradation. (PubMed id 20140013)1, 9 Thalappilly S....Dusetti N.J. (2010)
- Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation. (PubMed id 11909943)1, 9 Booden M.A....Der C.J. (2002)
|
External Searches for VAV2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VAV2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VAV2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing VAV2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for VAV2 gene:
Search GeneIP for patents involving VAV2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VAV2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for VAV2 | | OriGene shRNA RFP for VAV2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VAV2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VAV2 | | | OriGene Protein Over-expression Lysate for VAV2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VAV2 | | OriGene 3'-UTR Clone for VAV2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VAV2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for VAV2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VAV2 | | OriGene Custom Protein Services for VAV2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VAV2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VAV2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAV2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VAV2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VAV2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VAV2 |
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| | Antibodies & Assays for VAV2 |
| | | | Search Tocris compounds for VAV2 |
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 | | | VAV2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAV2 |
|  |  |  | | | | ThermoFisher Antibodies for VAV2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VAV2 |
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