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VASH1 Gene

protein-coding   GIFtS: 51
GCID: GC14P077228

Vasohibin 1

(Previous name: KIAA1036)
(Previous symbol: KIAA1036)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Vasohibin 11 2
KIAA10361 2 3
vasohibin-12
VASH3

External Ids:    HGNC: 199641   Entrez Gene: 228462   Ensembl: ENSG000000712467   OMIM: 6090115   UniProtKB: Q7L8A93   

Export aliases for VASH1 gene to outside databases

Previous GC identifers: GC14P076299 GC14P057396


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for VASH1 Gene:
VASH1 (vasohibin 1) is a protein-coding gene. Diseases associated with VASH1 include female breast carcinoma, and severe pre-eclampsia. An important paralog of this gene is VASH2.

UniProtKB/Swiss-Prot: VASH1_HUMAN, Q7L8A9
Function: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as
well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the
migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but
inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation
and macrophage infiltration. Exhibits heparin-binding activity

Gene Wiki entry for VASH1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the VASH1 gene promoter:
         AhR   Egr-3   Egr-1   MyoD   LUN-1   CUTL1   LCR-F1   Arnt   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVASH1 promoter sequence
   Search Chromatin IP Primers for VASH1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VASH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.3   Ensembl cytogenetic band:  14q24.3   HGNC cytogenetic band: 14q24.3

VASH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VASH1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P077228:  view genomic region     (about GC identifiers)

Start:
77,228,235 bp from pter      End:
77,249,363 bp from pter
Size:
21,129 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: VASH1_HUMAN, Q7L8A9 (See protein sequence)
Recommended Name: Vasohibin-1  
Size: 365 amino acids; 40957 Da
Caution: Although probably secreted, it lacks a canonical signal sequence
Sequence caution: Sequence=AAD44361.1; Type=Erroneous gene model prediction; Sequence=BAA82988.2; Type=Erroneous
initiation;
Secondary accessions: Q96H02 Q9UBF4 Q9Y629
Alternative splicing: 2 isoforms:  Q7L8A9-1   Q7L8A9-2   

Explore the universe of human proteins at neXtProt for VASH1: NX_Q7L8A9

Explore proteomics data for VASH1 at MOPED

Post-translational modifications: 

  • 2 major forms (42 and 36 kDa) and 2 minors (32 and 27 kDa) may be processed by proteolytic cleavage. The largest
    form (42 kDa) seems to be secreted and the other major form (63 kDa) seems to accumulate within the cells or
    pericellular milieu. Polypeptide consisting of Met-77 to Arg-318 may correspond to the 27 kDa form and that
    consisting of Met-77 to Val-365 may correspond to the 36 kDa form1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See VASH1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055724.1  
    ENSEMBL proteins: 
     ENSP00000167106   ENSP00000451613   ENSP00000451908  

    VASH1 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for VASH1

    VASH1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for VASH1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR028132 Vasohibin-1
     IPR028131 Vasohibin

    Graphical View of Domain Structure for InterPro Entry Q7L8A9

    ProtoNet protein and cluster: Q7L8A9

    UniProtKB/Swiss-Prot: VASH1_HUMAN, Q7L8A9
    Similarity: Belongs to the vasohibin family


    VASH1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VASH1_HUMAN, Q7L8A9
    Function: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as
    well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the
    migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but
    inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation
    and macrophage infiltration. Exhibits heparin-binding activity
    Induction: By VEGF

    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Vash1):

     cardiovascular system 

    VASH1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Vash1tm1Ysat for VASH1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VASH1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for VASH1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VASH1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VASH1

    miRNA
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    miRTarBase miRNAs that target VASH1:
    hsa-mir-335-5p (MIRT017737)

    Block miRNA regulation of human, mouse, rat VASH1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VASH1 (see all 37):
    hsa-miR-3194-5p hsa-miR-429 hsa-miR-765 hsa-miR-29a hsa-miR-30d hsa-miR-486-3p hsa-miR-30a hsa-miR-1184
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Sino Biological Human cDNA Clone for VASH1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VASH1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VASH1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VASH1_HUMAN, Q7L8A9: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    extracellular5
    mitochondrion2
    cytoskeleton1
    cytosol1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA15467828
    GO:0005737cytoplasm IDA15467828
    GO:0005783endoplasmic reticulum IDA15467828
    GO:0045177apical part of cell IDA--

    VASH1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VASH1
    Interactions:

        Search GeneGlobe Interaction Network for VASH1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for VASH1 (Q7L8A93 ENSP000001671064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC23Q8N3003, ENSP000003615994I2D: score=1 STRING: ENSP00000361599
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IDA15467828
    GO:0001937negative regulation of endothelial cell proliferation IDA15467828
    GO:0007050cell cycle arrest IEA--
    GO:0009611response to wounding IDA--
    GO:0010596negative regulation of endothelial cell migration IGI--

    VASH1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VASH1

    1 Novoseek inferred chemical compound relationship for VASH1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    vegf 63.1 22 18486097 (3), 15649403 (2), 17095714 (2), 20035291 (2) (see all 10)



    VASH1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for VASH1 gene: 
    NM_014909.4  

    Unigene Cluster for VASH1:

    Vasohibin 1
    Hs.525479  [show with all ESTs]
    Unigene Representative Sequence: NM_014909
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000167106(uc001xst.2) ENST00000554237(uc001xss.3) ENST00000556038
    ENST00000553518 ENST00000554743
    miRNA
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    Block miRNA regulation of human, mouse, rat VASH1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate VASH1 (see all 37):
    hsa-miR-3194-5p hsa-miR-429 hsa-miR-765 hsa-miR-29a hsa-miR-30d hsa-miR-486-3p hsa-miR-30a hsa-miR-1184
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    GenScript: all cDNA clones in your preferred vector: VASH1 (NM_014909)
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    Primer
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    OriGene qPCR primer pairs and template standards for VASH1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VASH1
      QuantiTect SYBR Green Assays in human, mouse, rat VASH1
      QuantiFast Probe-based Assays in human, mouse, rat VASH1

    Additional mRNA sequence: 

    AB028959.1 AF055021.1 AK094330.1 AK291377.1 AL832588.2 BC009031.1 BC051896.1 

    9 DOTS entries:

    DT.453848  DT.311953  DT.70100318  DT.108020  DT.65284442  DT.100654054  DT.95241664  DT.100781249 
    DT.95375355 

    Selected AceView cDNA sequences (see all 166):

    BM990580 BQ233634 BE220471 AK094330 AL041425 BM708077 AI338488 AF055021 
    AW172651 BM675057 CK725196 BQ445879 H08665 BE349025 BM713191 BU782643 
    AI694412 AI801580 AI873697 AB028959 AW236989 AI990120 AA115240 CA389776 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VASH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGTGCTTG
    VASH1 Expression
    About this image


    VASH1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract
     
     Endothelium (Cardiovascular System)
             Endothelial-like cells
    VASH1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VASH1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.525479

    UniProtKB/Swiss-Prot: VASH1_HUMAN, Q7L8A9
    Tissue specificity: Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in
    brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of
    atherosclerotic lesions

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VASH1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for VASH1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vash11 , 5 vasohibin 11, 5 88.68(n)1
    92.88(a)1
      12 (40.84 cM)5
    2383281  NM_177354.41  NP_796328.21 
     866787005 
    chicken
    (Gallus gallus)
    Aves VASH11 vasohibin 1 83.1(n)
    86.62(a)
      423369  XM_003641364.2  XP_003641412.1 
    lizard
    (Anolis carolinensis)
    Reptilia VASH16
    vasohibin 1
    86(a)
    1 ↔ 1
    1(21397377-21413976)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia vash11 vasohibin 1 66.99(n)
    72.49(a)
      100216209  NM_001142178.1  NP_001135650.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000017481 vasohibin-1-like 72.95(n)
    72.2(a)
      100001748  XM_003200403.2  XP_003200451.1 


    ENSEMBL Gene Tree for VASH1 (if available)
    TreeFam Gene Tree for VASH1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for VASH1 gene
    VASH22  
    1 SIMAP similar gene for VASH1 using alignment to 2 protein entries:     VASH1_HUMAN (see all proteins):
    VASH2

    VASH1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VASH1 (see all 480)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs133792091,2
    C,F,H--77226307(+) ttcatT/Aagaca 1 -- us2k118Minor allele frequency- A:0.07NS EA NA WA CSA 2224
    rs1910883861,2
    --77226350(+) AAAGGA/CATTAG 1 -- us2k10--------
    rs801135951,2
    F--77226401(+) AATTTT/GAAAAC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1495406681,2
    --77226440(+) ATGTAC/TAGAGT 1 -- us2k10--------
    rs1857187611,2
    --77226572(+) TGTTGA/GTCCCT 1 -- us2k10--------
    rs1905399001,2
    --77226573(+) GTTGAC/TCCCTA 1 -- us2k10--------
    rs1431634921,2
    --77226576(+) GATCCC/TTAGTG 1 -- us2k10--------
    rs118475661,2
    C,F,H--77226654(+) TGGAGT/ACTTGC 1 -- us2k116Minor allele frequency- A:0.17NS EA NA WA 1442
    rs1823832441,2
    --77226692(+) GTTTCC/TGACCC 1 -- us2k10--------
    rs7305481,2
    C,F,O,A,H--77226721(+) GCTACG/CGGAGC 1 -- us2k124Minor allele frequency- C:0.29NA EA MN NS WA 2052

    HapMap Linkage Disequilibrium report for VASH1 (77228235 - 77249363 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for VASH1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VASH1
    DNA2.0 Custom Variant and Variant Library Synthesis for VASH1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609011    OMIM disorders: --

    16 diseases for VASH1:    
    About MalaCards
    female breast carcinoma    severe pre-eclampsia    bronchiolitis obliterans    pre-eclampsia
    eclampsia    bronchiolitis    proliferative diabetic retinopathy    diabetic retinopathy
    choroiditis    diabetic nephropathy    endotheliitis    hypoxia
    renal cell carcinoma    hepatocellular carcinoma    prostate cancer    prostatitis

    1 disease from the University of Copenhagen DISEASES database for VASH1:
    Female breast carcinoma

    VASH1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for VASH1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 15 19498005 (4), 19886910 (2), 15467828 (1)


    Export disorders for VASH1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VASH1 gene, integrated from 10 sources (see all 49):
    (articles sorted by number of sources associating them with VASH1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Vasohibin prevents arterial neointimal formation through angiogenesis inhibition. (PubMed id 16707096)1, 2, 9 Yamashita H.... Sato Y. (Biochem. Biophys. Res. Commun. 2006)
    2. Gene regulation of a novel angiogenesis inhibitor, vasohibin, in endothelial cells. (PubMed id 15649403)1, 2, 9 Shimizu K.... Sato Y. (Biochem. Biophys. Res. Commun. 2005)
    3. Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis. (PubMed id 15467828)1, 2, 9 Watanabe K.... Sato Y. (J. Clin. Invest. 2004)
    4. Multiple processing forms and their biological activities of a novel angiogenesis inhibitor vasohibin. (PubMed id 16488400)1, 2, 9 Sonoda H.... Sato Y. (Biochem. Biophys. Res. Commun. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (Nature 2003)
    7. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R.... Ohara O. (DNA Res. 1999)
    8. Vasohibin-1 in human breast carcinoma: a potential negative feedback regulator of angiogenesis. (PubMed id 19037993)1, 9 Tamaki K....Sasano H. (Cancer Sci. 2009)
    9. Expression of vasohibin as a novel endothelium-derived angiogenesis inhibitor in endometrial cancer. (PubMed id 18325046)1, 9 Yoshinaga K....Sato Y. (Cancer Sci. 2008)
    10. Inflammatory cytokine-induced expression of vasohibin-1 by rheumatoid synovial fibroblasts. (PubMed id 20035291)1, 9 Miyake K....Makino H. (Acta Med. Okayama 2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22846 HGNC: 19964 AceView: KIAA1036 Ensembl:ENSG00000071246 euGenes: HUgn22846
    ECgene: VASH1 H-InvDB: VASH1

    (According to HUGE)
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    HUGE: KIAA1036

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VASH1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VASH1 gene:
    Search GeneIP for patents involving VASH1

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