External Ids for VASH1 Gene
Previous HGNC Symbols for VASH1 Gene
Previous GeneCards Identifiers for VASH1 Gene
GeneCards Summary for VASH1 Gene
VASH1 (Vasohibin 1) is a Protein Coding gene. An important paralog of this gene is VASH2.
UniProtKB/Swiss-Prot for VASH1 Gene
Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.