VARS2 Gene
protein-coding GIFtS: 59
GCID: GC06P030876
|
|
valyl-tRNA synthetase 2, mitochondrial(Previous names: valyl-tRNA synthetase 2-like, valyl-tRNA synthetase like,...)
(Previous symbols: VARS2L, VARSL)
| |
Aliases
for VARS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Valyl-TRNA Synthetase 2, Mitochondrial1 2 | | Valyl-TRNA Synthetase 2-Like1 | | VARS2L1 2 3 | | ValRS3 | | VARSL1 2 3 | | Valine TRNA Ligase 2, Mitochondrial (Putative)2 | | KIAA18851 3 5 | | Valine--TRNA Ligase, Mitochondrial2 | | G7a1 2 | | Valyl-TRNA Synthetase, Mitochondrial2 | | Valyl-TRNA Synthetase 2, Mitochondrial (Putative)1 2 | | ValRS3 | | Valyl-TRNA Synthetase Like1 2 | | Valyl-TRNA Synthetase3 | | EC 6.1.1.93 8 | | Valyl-TRNA Synthetase-Like3 | | DKFZP434L14351 | | EC 6.1.18 |
Export aliases for VARS2 gene to outside databasesPrevious GC identifers: GC06M031816 GC06M031516 GC06M031851 GC06M031852 GC06M031853 GC06Pc31014 GC06P030992 GC06P030682 |
Summaries
for VARS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for VARS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the VARS2 gene promoter:
E2F-4 E2F-3a E2F-5 STAT1 E2F-2 CREB E2F E2F-1 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for VARS2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VARS2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.33 Ensembl cytogenetic band: 6p21.33 HGNC cytogenetic band: 6p21.33VARS2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P030876: view genomic region
(about GC identifiers)
Start:
|
30,876,019 bp from pter |
End:
|
30,894,236 bp from pter |
Size:
|
18,218 bases |
Orientation:
|
plus strand |
5 alternative locations:
| Chr6+,ALT_REF_LOCI_6 30,865,607-30,919,416 | Chr6+,ALT_REF_LOCI_4 30,849,720-30,861,976 | Chr6+,ALT_REF_LOCI_2 30,865,890-30,923,147 | | Chr6+,ALT_REF_LOCI_3 30,866,734-30,896,002 | Chr6+,ALT_REF_LOCI_5 30,875,360-30,887,623 |
|
Proteins
for VARS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SYVM_HUMAN, Q5ST30 (See
protein sequence)Recommended Name: Valine--tRNA ligase, mitochondrial precursor Size: 1063 amino acids; 118490 Da
Subcellular location: Mitochondrion (Potential)
Sequence caution: Sequence=BAB15191.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB67778.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAD92716.1;Type=Miscellaneous discrepancy; Note=The sequence differs from that shown because it seems to be derived from apre-mRNA; Sequence=CAM24842.1; Type=Erroneous gene model prediction; Sequence=CAM25404.1; Type=Erroneous gene modelprediction; Sequence=CAQ06763.1; Type=Erroneous gene model prediction; Sequence=CAQ09774.1; Type=Erroneous gene modelprediction; Sequence=CAQ10925.1; Type=Erroneous gene model prediction;
Secondary accessions: A2ABL7 B4DET4 B4E3P5 F5GXJ0 F5H323 Q2M2A0 Q59FI1 Q5SQ96 Q5SS98 Q6DKJ5 Q6ZV24Q96GN2 Q96H77 Q96Q02 Q9H6R2 Q9UFH7Alternative splicing: 4 isoforms: Q5ST30-1 Q5ST30-2 Q5ST30-3 Q5ST30-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for VARS2: NX_Q5ST30
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5ST30
4/28 DME Specific Peptides for VARS2 (Q5ST30) (see all 28)
VARS2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001161205.1 NP_001161206.1 NP_065175.4
ENSEMBL proteins: ENSP00000316092 ENSP00000403749 ENSP00000416390 ENSP00000441000 ENSP00000394802 ENSP00000438200 Reactome Protein details: Q5ST30
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IEA | -- |
VARS2 for ontologies About GeneDecksing
VARS2 Antibody Products:
Assay Products for VARS2: |
Protein
Domains /
Families
for VARS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
VARS2 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q5ST30ProtoNet protein and cluster: Q5ST30 3 Blocks protein families: IPB002300 Aminoacyl-tRNA synthetase IPB002303 Valyl-tRNA synthetase signature IPB013155 tRNA synthetase
UniProtKB/Swiss-Prot: SYVM_HUMAN, Q5ST30Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family |
Function
for VARS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SYVM_HUMAN, Q5ST30Catalytic activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) Genatlas biochemistry entry for VARS2:valyl-tRNA synthetase 2,same as G7a,see HTFAG@
Enzyme Numbers (IUBMB): EC 6.1.1.91 2 EC 6.1.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): VARS2 (NM_020442) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VARS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VARS2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VARS2 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002161 | aminoacyl-tRNA editing activity |
IEA | -- | | GO:0004812 | aminoacyl-tRNA ligase activity |
-- | -- | | GO:0004832 | valine-tRNA ligase activity |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- |
VARS2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for VARS2:
|
Pathways & Interactions
for VARS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Valine, leucine and isoleucine biosynthesis | | | 3 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for VARS2
2 
Kegg Pathways (Kegg details for VARS2):
VARS2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for VARS2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/232 Interacting proteins for VARS2 (Q5ST302, 3 ENSP000003948024) via UniProtKB, MINT, STRING, and/or I2D (see all 232)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006418 | tRNA aminoacylation for protein translation |
TAS | -- | | GO:0006438 | valyl-tRNA aminoacylation |
IEA | -- | | GO:0010467 | gene expression |
TAS | -- |
VARS2 for ontologies About GeneDecksing
|
Drugs & Compounds
for VARS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for VARS2
5 HMDB Compounds for VARS2 About this table
Search CenterWatch for drugs/clinical trials and news about VARS2 / SYVM
|
Transcripts
for VARS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for VARS2 gene (3 alternative transcripts): NM_001167733.1 NM_001167734.1 NM_020442.4 Unigene Cluster for VARS2: Valyl-tRNA synthetase 2, mitochondrial Hs.597526 [show with all ESTs]Unigene Representative Sequence: NM_00116773414 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000477288(uc003nsa.1 uc003nsc.2) ENST00000321897(uc003nsd.3 uc011dmx.2 uc011dmy.2 uc011dmz.2 uc011dna.2 uc011dnb.2 uc011dnc.2)
ENST00000428017 ENST00000467717 ENST00000421263 ENST00000490699 ENST00000469358(uc011dnd.2 uc010jsg.2)
ENST00000476162 ENST00000465948 ENST00000477052 ENST00000473916(uc010jsh.2)
ENST00000541562 ENST00000416670 ENST00000542001
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): VARS2 (NM_020442) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for VARS2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VARS2 |
Additional cDNA sequence: AK000511.1 AK025618.1 AK026063.1 AK094483.1 AK125069.1 AK293780.1 AK294451.1 AK303415.1 AK304807.1 AK315733.1 AL122037.1 BC008844.2 BC009355.2 BC063427.1 BC073838.1 BC112054.1 BC113605.1 BC143534.1 BC143535.1 BC143536.1 10 DOTS entries: DT.414330 DT.99956622 DT.97848345 DT.101967025 DT.100783857 DT.100783864 DT.100783861 DT.121348680 DT.100783856 DT.95370180 24/149 AceView cDNA sequences (see all 149): BQ056176 BG910407 BQ065988 BQ057929 AA496582 BQ641944 BQ643980 M78120 BQ063571 BM852646 AW439283 BQ065373 BQ066769 BM827439 BQ061525 CB161826 BQ064403 BQ883157 BQ057069 BQ063639 AB067472 BG910473 BQ061568 BQ061299
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for VARS2 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · |
|---|
|
| SP1: | | | - | | - | | | | | | - | | | | | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | |
| SP4: | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14b | · | 14c |
|---|
|
| SP1: | | | | | |
| SP2: | | | | | |
| SP3: | | | | | |
| SP4: | | | | | |
| SP5: | | | | |
ECgene alternative splicing isoforms for VARS2
|
Expression
for VARS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| VARS2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGCTGCAGG
About this image
See VARS2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VARS2
SOURCE GeneReport for Unigene cluster: Hs.597526
SABiosciences Expression via Pathway-Focused PCR Array including VARS2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VARS2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat VARS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VARS2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VARS2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VARS2 |
Orthologs
for VARS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for VARS2 gene from 7/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
VARS26 |
-- |
57(a) |
1 ↔ 1 |
2(191555897-191586316) |
zebrafish
(Danio rerio) |
Actinopterygii |
vars21 |
valyl-tRNA synthetase 2, mitochondrial (putative) |
57.73(n)
54.72(a) |
|
100170827 NM_001130661.1 NP_001124133.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Aats-val3 |
valyl-tRNA aminoacylation glutamate-tRNA
ligase |
61(a)
(best of 2) |
|
49F7 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
vrs-23 |
-- |
53(a)
(best of 2) |
|
I(13556522-13567394) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
VALRS6EMB22476 |
valyl-tRNA synthetase |
40(a)34(a) |
1 ↔ manypossible ortholog |
1(5008244-5014533) 5(5485353-5493520) |
rice
(Oryza sativa) |
Liliopsida |
----(see all 5) |
valyl-tRNA synthetase, putative, expressed(see all 5) |
43(a)41(a)(see all 5) |
many ↔ manymany ↔ many(see all 5) |
3(12421200-12431416) 3(665219-673056) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
valS6 |
valyl-tRNA synthetase |
34(a) |
possible ortholog |
Chromosome(4479005-4481860) |
ENSEMBL Gene Tree for VARS2 (if available)
TreeFam Gene Tree for VARS2 (if available) |
Paralogs
for VARS2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for VARS2 gene
- VARS2
1 SIMAP similar gene for VARS2 using alignment to 13 protein entries: SYVM_HUMAN (see all proteins):VARS
VARS2 for paralogs About GeneDecksing
|
Genomic Variants
for VARS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for VARS2 (30876019 - 30894236 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for VARS2
1 Indel: 47098 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VARS2 |
|
Disorders
/ Diseases
for VARS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
VARS2 for disorders About GeneDecksing
OMIM gene information: 612802
OMIM disorders: --
7  diseases for VARS2: About MalaCardssystemic lupus erythematosus lupus erythematosus breast cancer pneumonia
tuberculosis malaria mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: VARS2 (7 documents)
Export disorders for VARS2 gene to outside databases
|
Publications
for VARS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for VARS2 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with VARS2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2, 3 Nagase T....Ohara O. (2001)
- Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation. (PubMed id 18400783)1, 3 Rorbach J....Lightowlers R.N. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Evidence that gene G7a in the human major histocompatibility complex encodes valyl-tRNA synthetase. (PubMed id 1898367)1, 3 Hsieh H.-L. and Campbell R.D. (1991)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- VARS2 V552V variant as prognostic marker in patients with early breast cancer. (PubMed id 20503108)1 Chae Y.S....Lee S.W. (2010)
|
External Searches for VARS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing VARS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing VARS2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing VARS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for VARS2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for VARS2 gene:
Search GeneIP for patents involving VARS2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for VARS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for VARS2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VARS2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VARS2 | | | OriGene Protein Over-expression Lysate for VARS2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for VARS2 | | OriGene 3'-UTR Clone for VARS2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VARS2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for VARS2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for VARS2 | | OriGene Custom Protein Services for VARS2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat VARS2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VARS2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VARS2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VARS2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VARS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VARS2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for VARS2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | VARS2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VARS2 |
|  |  |  | | | | Search ThermoFisher Antibodies for VARS2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VARS2 |
|
|
|
|
